Stigma resistance in online child free communities : the limitations of choice rhetoric
- Morison, Tracy, Macleod, Catriona I, Lynch, Ingrid, Mijas, Magda, Shivakumar, Seemanthini T
- Authors: Morison, Tracy , Macleod, Catriona I , Lynch, Ingrid , Mijas, Magda , Shivakumar, Seemanthini T
- Date: 2015
- Language: English
- Type: Article
- Identifier: vital:6311 , http://hdl.handle.net/10962/d1019799 , http://journals.sagepub.com/doi/10.1177/0361684315603657
- Description: People who are voluntarily childless, or ‘‘childfree,’’ face considerable stigma. Researchers have begun to explore how these individuals respond to stigma, usually focusing on interpersonal stigma management strategies. We explored participants’ responses to stigma in a way that is cognisant of broader social norms and gender power relations. Using a feminist discursive psychology framework, we analysed women’s and men’s computer-assisted communication about their childfree status. Our analysis draws attention to ‘‘identity work’’ in the context of stigma. We show how the strategic use of ‘‘choice’’ rhetoric allowed participants to avoid stigmatised identities and was used in two contradictory ways. On the one hand, participants drew on a ‘‘childfree-by-choice script,’’ which enabled them to hold a positive identity of themselves as autonomous, rational, and responsible decision makers. On the other hand, they mobilised a ‘‘disavowal of choice script’’ that allowed a person who is unable to choose childlessness (for various reasons) to hold a blameless identity regarding deviation from the norm of parenthood. We demonstrate how choice rhetoric allowed participants to resist stigma and challenge pronatalism to some extent; we discuss the political potential of these scripts for reproductive freedom.
- Full Text:
- Date Issued: 2015
- Authors: Morison, Tracy , Macleod, Catriona I , Lynch, Ingrid , Mijas, Magda , Shivakumar, Seemanthini T
- Date: 2015
- Language: English
- Type: Article
- Identifier: vital:6311 , http://hdl.handle.net/10962/d1019799 , http://journals.sagepub.com/doi/10.1177/0361684315603657
- Description: People who are voluntarily childless, or ‘‘childfree,’’ face considerable stigma. Researchers have begun to explore how these individuals respond to stigma, usually focusing on interpersonal stigma management strategies. We explored participants’ responses to stigma in a way that is cognisant of broader social norms and gender power relations. Using a feminist discursive psychology framework, we analysed women’s and men’s computer-assisted communication about their childfree status. Our analysis draws attention to ‘‘identity work’’ in the context of stigma. We show how the strategic use of ‘‘choice’’ rhetoric allowed participants to avoid stigmatised identities and was used in two contradictory ways. On the one hand, participants drew on a ‘‘childfree-by-choice script,’’ which enabled them to hold a positive identity of themselves as autonomous, rational, and responsible decision makers. On the other hand, they mobilised a ‘‘disavowal of choice script’’ that allowed a person who is unable to choose childlessness (for various reasons) to hold a blameless identity regarding deviation from the norm of parenthood. We demonstrate how choice rhetoric allowed participants to resist stigma and challenge pronatalism to some extent; we discuss the political potential of these scripts for reproductive freedom.
- Full Text:
- Date Issued: 2015
Men's pathways to parenthood: Silences and heterosexual gender norms
- Morison, Tracy, Macleod, Catriona I
- Authors: Morison, Tracy , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: Book
- Identifier: vital:548 , http://hdl.handle.net/10962/d1018815 , http://www.hsrcpress.ac.za/product.php?productid=2332
- Description: How does the decision to become a parent unfold for heterosexual men? Is becoming a father a 'decision' at all or a series of events? These questions are the starting point for this critical book, in which the authors unravel the social and interpersonal processes – shaped by deeply entrenched socio-cultural norms – that come to bear on parenthood decision-making in the South African context. Drawing on the narratives of white, Afrikaans women and men, Men's Pathways to Parenthood uses an innovative discursive method to illuminate the roles masculinity, whiteness, class, and heteronormativity play in these accounts. Men's Pathways to Parenthood addresses an under-researched topic in gender studies – namely, men and reproductive decision-making – and will be an important resource for scholars in gender studies, sexualities, and reproductive health, as well as those interested in innovative approaches to discursive research.
- Full Text:
- Date Issued: 2015
- Authors: Morison, Tracy , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: Book
- Identifier: vital:548 , http://hdl.handle.net/10962/d1018815 , http://www.hsrcpress.ac.za/product.php?productid=2332
- Description: How does the decision to become a parent unfold for heterosexual men? Is becoming a father a 'decision' at all or a series of events? These questions are the starting point for this critical book, in which the authors unravel the social and interpersonal processes – shaped by deeply entrenched socio-cultural norms – that come to bear on parenthood decision-making in the South African context. Drawing on the narratives of white, Afrikaans women and men, Men's Pathways to Parenthood uses an innovative discursive method to illuminate the roles masculinity, whiteness, class, and heteronormativity play in these accounts. Men's Pathways to Parenthood addresses an under-researched topic in gender studies – namely, men and reproductive decision-making – and will be an important resource for scholars in gender studies, sexualities, and reproductive health, as well as those interested in innovative approaches to discursive research.
- Full Text:
- Date Issued: 2015
Rhodes University Research Report 2015
- Rhodes University, Gillitt, Tarryn, Goba, Busi, Macgregor, Jill, Roberts, Jaine, Dore, Sally
- Authors: Rhodes University , Gillitt, Tarryn , Goba, Busi , Macgregor, Jill , Roberts, Jaine , Dore, Sally
- Date: 2015
- Language: English
- Type: Text
- Identifier: http://hdl.handle.net/10962/59298 , vital:27546
- Description: From Foreword by Dr Sizwe Mabizela: A further feature of research at Rhodes University has long been international collaborations, many of them responsible for raising the international competitiveness and voice of scholarship involving Rhodes academics and students. In March 2015, Rhodes University became a founder member of the African Research Universities’ Alliance (ARUA), launched at the African Higher Education Summit in Senegal. Leading universities with strong programmes of research and Postgraduate training formed the network of 16 institutions, which aim to bring together intersecting and complementary strengths in the interest of building critical mass in the key development priorities of the African continent. , A publication of the Rhodes University Research Office, compiled and edited by Tarryn Gillitt, Busi Goba, Patricia Jacob, Jill Macgregor and Jaine Roberts. Design & Layout: Sally Dore.
- Full Text:
- Date Issued: 2015
- Authors: Rhodes University , Gillitt, Tarryn , Goba, Busi , Macgregor, Jill , Roberts, Jaine , Dore, Sally
- Date: 2015
- Language: English
- Type: Text
- Identifier: http://hdl.handle.net/10962/59298 , vital:27546
- Description: From Foreword by Dr Sizwe Mabizela: A further feature of research at Rhodes University has long been international collaborations, many of them responsible for raising the international competitiveness and voice of scholarship involving Rhodes academics and students. In March 2015, Rhodes University became a founder member of the African Research Universities’ Alliance (ARUA), launched at the African Higher Education Summit in Senegal. Leading universities with strong programmes of research and Postgraduate training formed the network of 16 institutions, which aim to bring together intersecting and complementary strengths in the interest of building critical mass in the key development priorities of the African continent. , A publication of the Rhodes University Research Office, compiled and edited by Tarryn Gillitt, Busi Goba, Patricia Jacob, Jill Macgregor and Jaine Roberts. Design & Layout: Sally Dore.
- Full Text:
- Date Issued: 2015
The development of biological tools to aid in the genetic investigation of the black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros mitochondrial genomes
- Authors: Parsons, Michelle
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/56059 , vital:26769
- Description: The black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros are found in South Africa. A decline in the populations of these species has resulted due to human activities such as habitat fragmentation and poaching. This has contributed to the loss of genetic diversity amongst the black and white rhinoceros. Conservation and anti-poaching efforts are needed to help maintain genetic diversity. These efforts could be improved through the development of non-invasive techniques to examine DNA from threatened animals. The aim of this research was to develop a molecular technique which would allow for the identification of the black and white rhinoceros and to develop a molecular technique which would allow for intraspecies genetic variation to be examined. DNA extractions were performed on matched faecal and tissue samples that were collected from two regions in South Africa. Polymerase chain reaction (PCR) primer sets were designed to investigate several regions of the rhinoceros mitochondrial genome. PCR optimisation was completed for the target regions. Sequencing was conducted on all final PCR products. The cytochrome c oxidase subunit 1 (COIi) gene allowed for the rhinoceros family to be identified. This region was digested with the HindIII restriction enzyme, which allowed for the specific identification of either the black or white rhinoceros. A subsequent region of the cytochrome c oxidase subunit 1 (COIii) as well as the D-loop, hypervariable regions (HV1 and HV2), cytochrome b (cytb) and 16s rRNA regions were investigated. These regions displayed potential for establishing geographic origin for black rhinoceros samples, whereas the D-loop and HV2 show potential for the white rhinoceros. The white rhinoceros displayed sequence variation in the HV2 and cytb region, while variation was observed in the COIi and HV1 for the black rhinoceros. All investigated target regions allowed for the rhinoceros family to be identified. The COI (COIi and COIii), HV2 and cytb regions allowed for the subspecies of rhinoceros to be identified, however the D-loop was not able to identify the white rhinoceros species. The 16s rRNA and HV1 regions allowed for the correct subspecies of rhinoceros to be identified, however as the primers were only compatible for the black rhinoceros therefore a subsequent investigation is required for the white rhinoceros. The establishment of this novel PCR based technique to identify white and black rhinoceros will allow for efficient species identification in wildlife forensic cases. A biological method was established to study intraspecies variation for the white and black rhinoceros; however the investigated target regions did not yield sufficient genetic variation. The core techniques developed in this study will be valuable for future studies that wish to investigate genetic variation in mammal species.
- Full Text:
- Date Issued: 2015
- Authors: Parsons, Michelle
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/56059 , vital:26769
- Description: The black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros are found in South Africa. A decline in the populations of these species has resulted due to human activities such as habitat fragmentation and poaching. This has contributed to the loss of genetic diversity amongst the black and white rhinoceros. Conservation and anti-poaching efforts are needed to help maintain genetic diversity. These efforts could be improved through the development of non-invasive techniques to examine DNA from threatened animals. The aim of this research was to develop a molecular technique which would allow for the identification of the black and white rhinoceros and to develop a molecular technique which would allow for intraspecies genetic variation to be examined. DNA extractions were performed on matched faecal and tissue samples that were collected from two regions in South Africa. Polymerase chain reaction (PCR) primer sets were designed to investigate several regions of the rhinoceros mitochondrial genome. PCR optimisation was completed for the target regions. Sequencing was conducted on all final PCR products. The cytochrome c oxidase subunit 1 (COIi) gene allowed for the rhinoceros family to be identified. This region was digested with the HindIII restriction enzyme, which allowed for the specific identification of either the black or white rhinoceros. A subsequent region of the cytochrome c oxidase subunit 1 (COIii) as well as the D-loop, hypervariable regions (HV1 and HV2), cytochrome b (cytb) and 16s rRNA regions were investigated. These regions displayed potential for establishing geographic origin for black rhinoceros samples, whereas the D-loop and HV2 show potential for the white rhinoceros. The white rhinoceros displayed sequence variation in the HV2 and cytb region, while variation was observed in the COIi and HV1 for the black rhinoceros. All investigated target regions allowed for the rhinoceros family to be identified. The COI (COIi and COIii), HV2 and cytb regions allowed for the subspecies of rhinoceros to be identified, however the D-loop was not able to identify the white rhinoceros species. The 16s rRNA and HV1 regions allowed for the correct subspecies of rhinoceros to be identified, however as the primers were only compatible for the black rhinoceros therefore a subsequent investigation is required for the white rhinoceros. The establishment of this novel PCR based technique to identify white and black rhinoceros will allow for efficient species identification in wildlife forensic cases. A biological method was established to study intraspecies variation for the white and black rhinoceros; however the investigated target regions did not yield sufficient genetic variation. The core techniques developed in this study will be valuable for future studies that wish to investigate genetic variation in mammal species.
- Full Text:
- Date Issued: 2015
The exploration of influence as a leadership competency amongst emerging adult males
- Authors: Munyai, Pfarelo Pardon
- Date: 2015
- Subjects: Leadership , Leadership -- Psychological aspects , Influence (Psychology) , Control (Psychology) , Social media , Executives -- Training of , Executive ability , College students , Young adults , Educational leadership , Executive coaching , Male college students , Leadership -- Study and teaching (Higher) , College student government
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:852 , http://hdl.handle.net/10962/d1017520
- Description: The association between leadership, influence and power is well developed in the literature. However, there is a notable lack of research on youth leadership development, especially as it pertains to their exercise of influence. This paper was borne out of the need to explore how youth - emerging adults’ males in particular - exercise influence as a leadership competency within their voluntary leadership positions. Using semi-structured face-to-face interviews and the Critical Incident Technique (CIT), the research primarily focused on influence tactics and how they were employed. This included assessing the related power bases and principles of influence that were manifest, as well as the learning and development that occurred when reflecting on the outcome of the influence process. Data was analysed using an open coding procedure. Incidents explored in the study were primarily interpersonal in nature. This was reminiscent of lateral influence that characterised the peer to peer contextual environment of the study. The study found that in their influence pursuits, emerging adults followed a rational approach to influence. The distinguishable power bases and their relative importance in application were context dependent (Krause and Kearney, 2006:59-86). In addition, various proactive influence tactics were employed with a leaning towards those perceived as positive, honest and non-manipulative in application, which was congruent with Head Student role expectations and the culture of the organization. The utilization of social media as a communication platform from which various tactics could be launched was a novel and notable finding. Consequently, the results were presented primarily under two themes, exploring how tactics of influence are used face to face and via the social media platform. In addition, the study emphasised the ethical implications of the exercise of influence in both of these platforms and related to this, the challenge of influencing friends or close associates, without undermining leadership integrity. Overall, the various influence incidents presented and their outcomes, evidently shaped leadership development by reinforcing tactics which worked and stimulating continuous reflection and learning, adaptive strategies and the development of new means to deal with resistance and non-compliance. All of these are critical to shaping future influence behaviour. Primary recommendations include the need for a proactive approach to educating youth on leadership and influence through formal programmes, if they were to be empowered with tools to develop and maximize their leadership potential. Equally, practitioners need to be sensitized to the significance of their role as catalysts in nurturing youth leadership development. In addition, the novel use of social media as a leadership influence platform was recognised as significant and as such, a candidate for further research. Beyond the limited scope of this study, other angles worthy of further research include, factoring in elements such as gender, cross-cultural differences and the aspect of voluntary versus incentivised (or paid) leadership positions. The research is presented in an academic paper format, and is structured in three sections. These sections are written up as relatively independent sections, but are complementary in covering the full scope of the research. Section One, which is essentially a paper in a format of an academic journal article, represent the primary section and covers the results of the study, together with discussions and recommendations. This is followed by a literature review (i.e. Section Two), which delves into all the relevant literature explored. Section Three covers the methodology, research design and research procedure pursued. As part of the addendum, a comprehensive summary of the incidents explored is presented. This gives insight into the nature of the various incidents, the influence tactics preferred, power bases and influence principles manifested, together with the outcomes of the incidents. Furthermore, lessons drawn in reflection are noted, which participants viewed as critical, in that they shaped the way they now intend to exercise influence and thereby reflects their personal leadership development.
- Full Text:
- Date Issued: 2015
- Authors: Munyai, Pfarelo Pardon
- Date: 2015
- Subjects: Leadership , Leadership -- Psychological aspects , Influence (Psychology) , Control (Psychology) , Social media , Executives -- Training of , Executive ability , College students , Young adults , Educational leadership , Executive coaching , Male college students , Leadership -- Study and teaching (Higher) , College student government
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:852 , http://hdl.handle.net/10962/d1017520
- Description: The association between leadership, influence and power is well developed in the literature. However, there is a notable lack of research on youth leadership development, especially as it pertains to their exercise of influence. This paper was borne out of the need to explore how youth - emerging adults’ males in particular - exercise influence as a leadership competency within their voluntary leadership positions. Using semi-structured face-to-face interviews and the Critical Incident Technique (CIT), the research primarily focused on influence tactics and how they were employed. This included assessing the related power bases and principles of influence that were manifest, as well as the learning and development that occurred when reflecting on the outcome of the influence process. Data was analysed using an open coding procedure. Incidents explored in the study were primarily interpersonal in nature. This was reminiscent of lateral influence that characterised the peer to peer contextual environment of the study. The study found that in their influence pursuits, emerging adults followed a rational approach to influence. The distinguishable power bases and their relative importance in application were context dependent (Krause and Kearney, 2006:59-86). In addition, various proactive influence tactics were employed with a leaning towards those perceived as positive, honest and non-manipulative in application, which was congruent with Head Student role expectations and the culture of the organization. The utilization of social media as a communication platform from which various tactics could be launched was a novel and notable finding. Consequently, the results were presented primarily under two themes, exploring how tactics of influence are used face to face and via the social media platform. In addition, the study emphasised the ethical implications of the exercise of influence in both of these platforms and related to this, the challenge of influencing friends or close associates, without undermining leadership integrity. Overall, the various influence incidents presented and their outcomes, evidently shaped leadership development by reinforcing tactics which worked and stimulating continuous reflection and learning, adaptive strategies and the development of new means to deal with resistance and non-compliance. All of these are critical to shaping future influence behaviour. Primary recommendations include the need for a proactive approach to educating youth on leadership and influence through formal programmes, if they were to be empowered with tools to develop and maximize their leadership potential. Equally, practitioners need to be sensitized to the significance of their role as catalysts in nurturing youth leadership development. In addition, the novel use of social media as a leadership influence platform was recognised as significant and as such, a candidate for further research. Beyond the limited scope of this study, other angles worthy of further research include, factoring in elements such as gender, cross-cultural differences and the aspect of voluntary versus incentivised (or paid) leadership positions. The research is presented in an academic paper format, and is structured in three sections. These sections are written up as relatively independent sections, but are complementary in covering the full scope of the research. Section One, which is essentially a paper in a format of an academic journal article, represent the primary section and covers the results of the study, together with discussions and recommendations. This is followed by a literature review (i.e. Section Two), which delves into all the relevant literature explored. Section Three covers the methodology, research design and research procedure pursued. As part of the addendum, a comprehensive summary of the incidents explored is presented. This gives insight into the nature of the various incidents, the influence tactics preferred, power bases and influence principles manifested, together with the outcomes of the incidents. Furthermore, lessons drawn in reflection are noted, which participants viewed as critical, in that they shaped the way they now intend to exercise influence and thereby reflects their personal leadership development.
- Full Text:
- Date Issued: 2015
Women's micro-narratives of the process of abortion decision-making : justifying the decision to have an abortion
- Mavuso, Jabulile Mary-Jane Jace
- Authors: Mavuso, Jabulile Mary-Jane Jace
- Date: 2015
- Subjects: Abortion -- Psychological aspects , Pregnancy, Unwanted -- Psychological aspects , Narrative therapy , Post-abortion syndrome
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:3262 , http://hdl.handle.net/10962/d1017885
- Description: Much of the research on abortion is concerned with determining women’s psychological outcomes post-abortion. There is a small, but increasing, body of research around women’s experiences of abortion (conducted predominantly in Scandinavian countries where abortion laws are liberal). However, research around the decision-making process regarding abortion, particularly research that locates the decision to have an abortion within the economic, religious, social, political, and cultural aspects of women’s lives and that looks at women’s narratives, is virtually non-existent. Drawing on Foucauldian and feminist post-structuralism as well as a narrative-discursive approach, this study sought to explore women’s micro-narratives of the abortion decision-making process in terms of the discourses used to construct these micro-narratives and the subject positions made available within these discourses. This study also sought to determine whether the power relations referred to by participants contributed to unsupported and unsupportable pregnancies and the implications this had for reproductive justice. Purposive sampling was used to recruit a total of 25 participants from three different abortion facilities in the Eastern Cape. Participants were ‘Black’ women, mostly unemployed and unmarried with ages ranging between 19 and 35 years old. In analysing and interpreting participants’ narratives, the picture that emerged was an over-arching narrative in which women described the abortion decision as something that they were ‘forced’ into by their circumstances. To construct this narrative, women justified the decision to have an abortion by drawing on discourses that normalise certain practices located within the husband-wife and parent-child axes and make the pregnancy a problematic, unsupported and unsupportable one. Gendered and generational power relations reinforced this and contributed to the denial of reproductive justice
- Full Text:
- Date Issued: 2015
- Authors: Mavuso, Jabulile Mary-Jane Jace
- Date: 2015
- Subjects: Abortion -- Psychological aspects , Pregnancy, Unwanted -- Psychological aspects , Narrative therapy , Post-abortion syndrome
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:3262 , http://hdl.handle.net/10962/d1017885
- Description: Much of the research on abortion is concerned with determining women’s psychological outcomes post-abortion. There is a small, but increasing, body of research around women’s experiences of abortion (conducted predominantly in Scandinavian countries where abortion laws are liberal). However, research around the decision-making process regarding abortion, particularly research that locates the decision to have an abortion within the economic, religious, social, political, and cultural aspects of women’s lives and that looks at women’s narratives, is virtually non-existent. Drawing on Foucauldian and feminist post-structuralism as well as a narrative-discursive approach, this study sought to explore women’s micro-narratives of the abortion decision-making process in terms of the discourses used to construct these micro-narratives and the subject positions made available within these discourses. This study also sought to determine whether the power relations referred to by participants contributed to unsupported and unsupportable pregnancies and the implications this had for reproductive justice. Purposive sampling was used to recruit a total of 25 participants from three different abortion facilities in the Eastern Cape. Participants were ‘Black’ women, mostly unemployed and unmarried with ages ranging between 19 and 35 years old. In analysing and interpreting participants’ narratives, the picture that emerged was an over-arching narrative in which women described the abortion decision as something that they were ‘forced’ into by their circumstances. To construct this narrative, women justified the decision to have an abortion by drawing on discourses that normalise certain practices located within the husband-wife and parent-child axes and make the pregnancy a problematic, unsupported and unsupportable one. Gendered and generational power relations reinforced this and contributed to the denial of reproductive justice
- Full Text:
- Date Issued: 2015
The synthesis and analysis of (2R,3R)-1,1,4,4- tetraphenylbutane-1,2,3,4-tetraol (tetrol) and derivatives, and a study of their host potential
- Authors: Weitz, Selwyn Herbert
- Date: 2015
- Subjects: Chemistry, Organic
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/3735 , vital:20459
- Description: This investigation focussed on the inclusion and resolution ability of (2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetraol (TETROL), studies on the stoichiometry of its derivatives and the formation of inclusion compounds for single crystal analysis. The guest compounds that featured in the main study were cyclohexanone, 2-methylcyclohexanone, 3-methylcyclohexanone and 4-methylcyclohexanone. It was found that 3- and 4-methylcyclohexanone were trapped in their energetically unfavourable axial conformations in the inclusion crystal. Resolution experiments proved that (2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetraol can be used as a resolving agent for 2- and 3-methylcyclohexanone, with ee values of 13% and 22%, respectively (according to the method of Hiemstra), in favour of the R-enantiomer. Single crystal X-ray diffraction (SCXRD) studies, however, showed that 2-methylcyclohexanone was resolved with an ee of 30% in R. An ee of 56% in R was obtained for 3-methylcyclohexanone. Enantiomer enrichment of 2-methylcyclohexanone was achieved in basic medium (ee of 18% according to the method of Hiemstra) and showed that by using the host in either half or double the molar ratio of the guest, a higher ee was obtained than for a 1:1 ratio. The following TETROL derivatives were also synthesized and their stoichiometries with various guest compounds were determined: (2R,3R)-1,1,4,4-tetra(naphthalen-1-yl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(naphthalen-2-yl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(p-anisyl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(p-tolyl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(m-tolyl)butane-1,2,3,4-tetraol and; (2R,3R)-1,1,4,4-tetra(o-tolyl)butane-1,2,3,4-tetraol.
- Full Text:
- Date Issued: 2015
- Authors: Weitz, Selwyn Herbert
- Date: 2015
- Subjects: Chemistry, Organic
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/3735 , vital:20459
- Description: This investigation focussed on the inclusion and resolution ability of (2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetraol (TETROL), studies on the stoichiometry of its derivatives and the formation of inclusion compounds for single crystal analysis. The guest compounds that featured in the main study were cyclohexanone, 2-methylcyclohexanone, 3-methylcyclohexanone and 4-methylcyclohexanone. It was found that 3- and 4-methylcyclohexanone were trapped in their energetically unfavourable axial conformations in the inclusion crystal. Resolution experiments proved that (2R,3R)-1,1,4,4-tetraphenylbutane-1,2,3,4-tetraol can be used as a resolving agent for 2- and 3-methylcyclohexanone, with ee values of 13% and 22%, respectively (according to the method of Hiemstra), in favour of the R-enantiomer. Single crystal X-ray diffraction (SCXRD) studies, however, showed that 2-methylcyclohexanone was resolved with an ee of 30% in R. An ee of 56% in R was obtained for 3-methylcyclohexanone. Enantiomer enrichment of 2-methylcyclohexanone was achieved in basic medium (ee of 18% according to the method of Hiemstra) and showed that by using the host in either half or double the molar ratio of the guest, a higher ee was obtained than for a 1:1 ratio. The following TETROL derivatives were also synthesized and their stoichiometries with various guest compounds were determined: (2R,3R)-1,1,4,4-tetra(naphthalen-1-yl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(naphthalen-2-yl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(p-anisyl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(p-tolyl)butane-1,2,3,4-tetraol; (2R,3R)-1,1,4,4-tetra(m-tolyl)butane-1,2,3,4-tetraol and; (2R,3R)-1,1,4,4-tetra(o-tolyl)butane-1,2,3,4-tetraol.
- Full Text:
- Date Issued: 2015
Nonlinear optical studies of phthalocyanines and their conjugates with nanomaterials
- Authors: Sanusi, Sikiru Olukayode
- Date: 2015
- Subjects: Phthalocyanines , Nonlinear optics
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4545 , http://hdl.handle.net/10962/d1017925
- Description: A number of metallophthalocyanines (MPcs) and metal-free phthalocyanines (H₂Pcs) have been synthesized and characterized using various characterization tools such as ¹H-NMR, TOF mass spectrometry, FT-IR, UV-visible spectrophotometry and CHNS elemental analysis. Some of the MPcs were covalently linked to nanomaterials such as silica nanoparticles (SiNPs), single-walled carbon nanotubes (SWCNTs), magnetite nanoparticles (MNPs) and quantum dots (QDs), or embedded in polymer thin-films using poly(methyl methacrylate) (PMMA) and poly(acrylic acid) (PAA) as the polymer sources. The phthalocyanine-nanomaterial composites (Pc-NMCs) were characterized with FT-IR, UV-visible spectrophotometry, transmission electron microscopy (TEM), thermogravimetry analysis and X-ray diffractometry. The nonlinear optical (NLO) properties (using the open-aperture Z-scan technique) of the MPcs and the Pc-NMCs were investigated. In general, most of the investigated MPcs showed good optical limiting behaviors, except for a few, like the non-peripherally-substituted 2-pyridyloxy phthalocyanines, which showed inhibited NLO response as a result of the ring-strain effects. The absence of a metal center was found to greatly reduce the inherent high nonlinearities expected of some of the phthalocyanine complexes. The octaphenoxy derivatives (61a – 61e) were found to exhibit reverse saturable absorption (RSA) that depends on the singlet-singlet transitions, hence making them less reliable optical limiters. The optical limiting properties of the MPcs were improved in the presence of nanomaterials such as the QDs, MNPs and SWCNTs, with MPc-QDs showing the best optical limiting behavior of the three. SiNPs have no significant effect on the optical limiting behavior of the MPcs. The optical limiting properties of the MPcs were greatly enhanced in the presence of PMMA or PAA polymers. The PAA polymer showed better optical limiting behavior compared to PMMA
- Full Text:
- Date Issued: 2015
- Authors: Sanusi, Sikiru Olukayode
- Date: 2015
- Subjects: Phthalocyanines , Nonlinear optics
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4545 , http://hdl.handle.net/10962/d1017925
- Description: A number of metallophthalocyanines (MPcs) and metal-free phthalocyanines (H₂Pcs) have been synthesized and characterized using various characterization tools such as ¹H-NMR, TOF mass spectrometry, FT-IR, UV-visible spectrophotometry and CHNS elemental analysis. Some of the MPcs were covalently linked to nanomaterials such as silica nanoparticles (SiNPs), single-walled carbon nanotubes (SWCNTs), magnetite nanoparticles (MNPs) and quantum dots (QDs), or embedded in polymer thin-films using poly(methyl methacrylate) (PMMA) and poly(acrylic acid) (PAA) as the polymer sources. The phthalocyanine-nanomaterial composites (Pc-NMCs) were characterized with FT-IR, UV-visible spectrophotometry, transmission electron microscopy (TEM), thermogravimetry analysis and X-ray diffractometry. The nonlinear optical (NLO) properties (using the open-aperture Z-scan technique) of the MPcs and the Pc-NMCs were investigated. In general, most of the investigated MPcs showed good optical limiting behaviors, except for a few, like the non-peripherally-substituted 2-pyridyloxy phthalocyanines, which showed inhibited NLO response as a result of the ring-strain effects. The absence of a metal center was found to greatly reduce the inherent high nonlinearities expected of some of the phthalocyanine complexes. The octaphenoxy derivatives (61a – 61e) were found to exhibit reverse saturable absorption (RSA) that depends on the singlet-singlet transitions, hence making them less reliable optical limiters. The optical limiting properties of the MPcs were improved in the presence of nanomaterials such as the QDs, MNPs and SWCNTs, with MPc-QDs showing the best optical limiting behavior of the three. SiNPs have no significant effect on the optical limiting behavior of the MPcs. The optical limiting properties of the MPcs were greatly enhanced in the presence of PMMA or PAA polymers. The PAA polymer showed better optical limiting behavior compared to PMMA
- Full Text:
- Date Issued: 2015
Chemical constituents and biological studies of Tagetes minuta L. and Rauvolfia caffra Sond
- Authors: Mlala, Sithenkosi
- Date: 2015
- Language: English
- Type: Thesis , Masters , MSc (Organic Chemistry)
- Identifier: vital:11358 , http://hdl.handle.net/10353/d1021325
- Description: Consequently, specific parts or the whole plant can be used for various treatments. The aim of this study was to extract, isolate and characterize the biologically active volatile and non-volatile compounds from Tagetes minuta and Rauvolfia caffra respectively. Tagetes minuta plant was considered for extraction of essential oils using hydrodistillation method. Cis-β-ocimene (38.03%), caryophyllene oxide (18.04%), alloocimene (25.35 %), isopropyl tetradecanoate (17.02 %), cis-ocimene (38.14%) and trans-β-ocimene (37.03%) were the major components of essential oil analyzed from fresh stem, dried stem, fresh leaf, dried leaf, fresh flower and dried flower respectively. The volatile compounds were identified by Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography (GC). Essential oil of dried stem leaf and flower parts of T. minuta exhibit antioxidant activity as demonstrated by the DPPH and FRAP bioassays. Crude extracts were extracted from R. caffra stem bark using sequence of solvents namely n-hexane, dichloromethane, ethyl acetate, methanol and ethanol. A white powder, a β-sitosterol (non-volatile compound) was isolated by column chromatography from ethyl acetate fractions of R. caffra stem bark and identified on various spectroscopic techniques such as FTIR and (1D and 2D) NMR. Melting point was also determined to be a sharp 129-130 ºC. DCM, EA, MetOH and EtOH fractions as well as β-Sitosterol (compound SM/01), showed antioxidant activity when tested on DPPH, FRAP, total phenolic and flavonoid bioassays. This antioxidant activity might be due to the presence of hydroxyl groups in the compound and crude fractions. On the other hand, T. minuta’s essential oil showed high antioxidant activity when evaluated on the DPPH and FRAP bioassays, which can be attributed to the presence of oxygenated monoterpenes and sesquiterpenes known to act as free radical scavenging and reducing agents. The use of R. caffra stem bark extracts against hypertension and other diseases by traditional healers could be attributed to the presence of phytochemicals (polyphenols and flavonoids) with known health benefits. Thus, it is recommended that the plant should be exploited further using modern techniques involving separation and purification of compounds that can be used for drug formulation. This study supports the use of T. minuta and R. caffra as the potential natural antioxidant source to manage various diseases including hypertension.
- Full Text:
- Date Issued: 2015
- Authors: Mlala, Sithenkosi
- Date: 2015
- Language: English
- Type: Thesis , Masters , MSc (Organic Chemistry)
- Identifier: vital:11358 , http://hdl.handle.net/10353/d1021325
- Description: Consequently, specific parts or the whole plant can be used for various treatments. The aim of this study was to extract, isolate and characterize the biologically active volatile and non-volatile compounds from Tagetes minuta and Rauvolfia caffra respectively. Tagetes minuta plant was considered for extraction of essential oils using hydrodistillation method. Cis-β-ocimene (38.03%), caryophyllene oxide (18.04%), alloocimene (25.35 %), isopropyl tetradecanoate (17.02 %), cis-ocimene (38.14%) and trans-β-ocimene (37.03%) were the major components of essential oil analyzed from fresh stem, dried stem, fresh leaf, dried leaf, fresh flower and dried flower respectively. The volatile compounds were identified by Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography (GC). Essential oil of dried stem leaf and flower parts of T. minuta exhibit antioxidant activity as demonstrated by the DPPH and FRAP bioassays. Crude extracts were extracted from R. caffra stem bark using sequence of solvents namely n-hexane, dichloromethane, ethyl acetate, methanol and ethanol. A white powder, a β-sitosterol (non-volatile compound) was isolated by column chromatography from ethyl acetate fractions of R. caffra stem bark and identified on various spectroscopic techniques such as FTIR and (1D and 2D) NMR. Melting point was also determined to be a sharp 129-130 ºC. DCM, EA, MetOH and EtOH fractions as well as β-Sitosterol (compound SM/01), showed antioxidant activity when tested on DPPH, FRAP, total phenolic and flavonoid bioassays. This antioxidant activity might be due to the presence of hydroxyl groups in the compound and crude fractions. On the other hand, T. minuta’s essential oil showed high antioxidant activity when evaluated on the DPPH and FRAP bioassays, which can be attributed to the presence of oxygenated monoterpenes and sesquiterpenes known to act as free radical scavenging and reducing agents. The use of R. caffra stem bark extracts against hypertension and other diseases by traditional healers could be attributed to the presence of phytochemicals (polyphenols and flavonoids) with known health benefits. Thus, it is recommended that the plant should be exploited further using modern techniques involving separation and purification of compounds that can be used for drug formulation. This study supports the use of T. minuta and R. caffra as the potential natural antioxidant source to manage various diseases including hypertension.
- Full Text:
- Date Issued: 2015
The influence of the physical environment, topography and time on the inshore distribution of invertebrate larvae : a multi-taxon approach
- Authors: Duna, Oliver Olwethu
- Date: 2015
- Subjects: Benthic animals -- Larvae , Benthic animals -- Ecology , Plankton -- Larvae
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5926 , http://hdl.handle.net/10962/d1017804
- Description: Coastal hydrodynamics regulate population dynamics through the distribution and dispersal of the meroplankton of many benthic invertebrates. I examined the hydrodynamics at four different sites on the south-east coast of South Africa and coupled them with larval sampling done at high temporal and spatial resolution. Day and night sampling was done at all four sites and a continuous 24 hour study was done in one site, both forms of sampling were carried out in autumn and spring. Samples were taken at two stations, 900 metres offshore and 300 metres apart, within each site. Water properties measured were depth, temperature and current velocity and direction. Plankton samples were collected using a plankton pump at various depths, from the surface, bottom and either side of the thermocline when present. A wide range of taxa (mostly bryozoans, bivalves, barnacles and decapods) was examined. 2-way ANOVAs were used to test the effects of time and depth on each taxon. In addition, multiple regression analyses were performed on each taxon to investigate the effects of hydrodynamics on the distribution of larvae. Bryozoanlarvae proved to be positively phototactic whilst bivalve veligers, barnacle larvae and decapod zoeae performed diel vertical migration. Turbulence and temperature had an effect on the vertical distribution/migration of decapod zoeae. These results highlight the role of taxon-specific responses to flow and the potential differential effects on larval retention and ultimately connectivity of benthic populations.
- Full Text:
- Date Issued: 2015
- Authors: Duna, Oliver Olwethu
- Date: 2015
- Subjects: Benthic animals -- Larvae , Benthic animals -- Ecology , Plankton -- Larvae
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5926 , http://hdl.handle.net/10962/d1017804
- Description: Coastal hydrodynamics regulate population dynamics through the distribution and dispersal of the meroplankton of many benthic invertebrates. I examined the hydrodynamics at four different sites on the south-east coast of South Africa and coupled them with larval sampling done at high temporal and spatial resolution. Day and night sampling was done at all four sites and a continuous 24 hour study was done in one site, both forms of sampling were carried out in autumn and spring. Samples were taken at two stations, 900 metres offshore and 300 metres apart, within each site. Water properties measured were depth, temperature and current velocity and direction. Plankton samples were collected using a plankton pump at various depths, from the surface, bottom and either side of the thermocline when present. A wide range of taxa (mostly bryozoans, bivalves, barnacles and decapods) was examined. 2-way ANOVAs were used to test the effects of time and depth on each taxon. In addition, multiple regression analyses were performed on each taxon to investigate the effects of hydrodynamics on the distribution of larvae. Bryozoanlarvae proved to be positively phototactic whilst bivalve veligers, barnacle larvae and decapod zoeae performed diel vertical migration. Turbulence and temperature had an effect on the vertical distribution/migration of decapod zoeae. These results highlight the role of taxon-specific responses to flow and the potential differential effects on larval retention and ultimately connectivity of benthic populations.
- Full Text:
- Date Issued: 2015
Invariant control systems and sub-Riemannian structures on lie groups: equivalence and isometries
- Authors: Biggs, Rory
- Date: 2015
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/64815 , vital:28607
- Description: In this thesis we consider invariant optimal control problems and invariant sub-Riemannian structures on Lie groups. Primarily, we are concerned with the equivalence and classification of problems (resp. structures). In the first chapter, both the class of invariant optimal control problems and the class of invariant sub-Riemannian structures are organised as categories. The latter category is shown to be functorially equivalent to a subcategory of the former category. Via the Pontryagin Maximum Principle, we associate to each invariant optimal control problem (resp. invariant sub-Riemannian structure) a quadratic Hamilton-Poisson system on the associated Lie-Poisson space. These Hamiltonian systems are also organised as a category and hence the Pontryagin lift is realised as a contravariant functor. Basic properties of these categories are investigated. The rest of this thesis is concerned with the classification (and investigation) of certain subclasses of structures and systems. In the second chapter, the homogeneous positive semidefinite quadratic Hamilton-Poisson systems on three-dimensional Lie-Poisson spaces are classified up to compatibility with a linear isomorphism; a list of 23 normal forms is exhibited. In the third chapter, we classify the invariant sub-Riemannian structures in three dimensions and calculate the isometry group for each normal form. By comparing our results with known results, we show that most isometries (in three dimensions) are in fact the composition of a left translation and a Lie group isomorphism. In the fourth and last chapter of this thesis, we classify the sub-Riemannian and Riemannian structures on the (2n + 1)-dimensional Heisenberg groups. Furthermore, we find the isometry group and geodesics of each normal form.
- Full Text:
- Date Issued: 2015
- Authors: Biggs, Rory
- Date: 2015
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/64815 , vital:28607
- Description: In this thesis we consider invariant optimal control problems and invariant sub-Riemannian structures on Lie groups. Primarily, we are concerned with the equivalence and classification of problems (resp. structures). In the first chapter, both the class of invariant optimal control problems and the class of invariant sub-Riemannian structures are organised as categories. The latter category is shown to be functorially equivalent to a subcategory of the former category. Via the Pontryagin Maximum Principle, we associate to each invariant optimal control problem (resp. invariant sub-Riemannian structure) a quadratic Hamilton-Poisson system on the associated Lie-Poisson space. These Hamiltonian systems are also organised as a category and hence the Pontryagin lift is realised as a contravariant functor. Basic properties of these categories are investigated. The rest of this thesis is concerned with the classification (and investigation) of certain subclasses of structures and systems. In the second chapter, the homogeneous positive semidefinite quadratic Hamilton-Poisson systems on three-dimensional Lie-Poisson spaces are classified up to compatibility with a linear isomorphism; a list of 23 normal forms is exhibited. In the third chapter, we classify the invariant sub-Riemannian structures in three dimensions and calculate the isometry group for each normal form. By comparing our results with known results, we show that most isometries (in three dimensions) are in fact the composition of a left translation and a Lie group isomorphism. In the fourth and last chapter of this thesis, we classify the sub-Riemannian and Riemannian structures on the (2n + 1)-dimensional Heisenberg groups. Furthermore, we find the isometry group and geodesics of each normal form.
- Full Text:
- Date Issued: 2015
Application of Baylis-Hillman methodology in the synthesis of HIV-1 enzyme inhibitors
- Authors: Manyeruke, Meloddy Hlatini
- Date: 2015
- Subjects: HIV infections , Enzyme inhibitors , AZT (Drug) , Bioconjugates
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4540 , http://hdl.handle.net/10962/d1017920
- Description: The application of Baylis-Hillman methodology has afforded access to a range of β-hydroxypropionate ester-AZT conjugates as potential dual-action HIV-1 IN/RT inhibitors. Two families comprising a total of nine β-hydroxypropionate ester-AZT conjugates were synthesised. The first family was accessed using O-benzylated salicylaldehydes and methyl acrylate and the second from unprotected salicylaldehydes using tert-butyl acrylate as the activated alkene. Spectroscopic methods were employed to fully characterize the compounds. Propargylation of the respective Baylis-Hillman adducts was achieved via conjugate addition of propargylamine. The resulting products were then employed in Cu(I)-catalysed “click” reactions with azidothymidine (AZT) to yield the desired β-hydroxypropionate ester-AZT conjugates. Exploratory studies were also conducted to access 4-hydroxycoumarins from Baylis-Hillman derived adducts and to construct customized chiral Baylis-Hillman reaction sites. Many 4- hydroxycoumarins are known to exhibit a wide range of biological activities, and extending Baylis-Hillman methodology to access these systems is an important challenge. Two approaches were investigated. The first involved the formation of a 4-phthalimidocoumarin, aromatisation and hydrolysis of which was expected to lead to the 4-hydroxycoumarin target. The second, a variation of the first, involved the use of 4-(chrolomethyl)coumarin intermediates. Unfortunately, while various intermediates were prepared and characterised, neither approach led ultimately to the desired targets. N-substituted borneol-10-sulfonamides were constructed from camphor-10- sulfonyl chloride as chiral Baylis-Hillman reaction sites. In a preliminary study, however, none of the N-substituted borneol-10-sulfonamides exhibited Baylis-Hillman catalytic activity.
- Full Text:
- Date Issued: 2015
- Authors: Manyeruke, Meloddy Hlatini
- Date: 2015
- Subjects: HIV infections , Enzyme inhibitors , AZT (Drug) , Bioconjugates
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4540 , http://hdl.handle.net/10962/d1017920
- Description: The application of Baylis-Hillman methodology has afforded access to a range of β-hydroxypropionate ester-AZT conjugates as potential dual-action HIV-1 IN/RT inhibitors. Two families comprising a total of nine β-hydroxypropionate ester-AZT conjugates were synthesised. The first family was accessed using O-benzylated salicylaldehydes and methyl acrylate and the second from unprotected salicylaldehydes using tert-butyl acrylate as the activated alkene. Spectroscopic methods were employed to fully characterize the compounds. Propargylation of the respective Baylis-Hillman adducts was achieved via conjugate addition of propargylamine. The resulting products were then employed in Cu(I)-catalysed “click” reactions with azidothymidine (AZT) to yield the desired β-hydroxypropionate ester-AZT conjugates. Exploratory studies were also conducted to access 4-hydroxycoumarins from Baylis-Hillman derived adducts and to construct customized chiral Baylis-Hillman reaction sites. Many 4- hydroxycoumarins are known to exhibit a wide range of biological activities, and extending Baylis-Hillman methodology to access these systems is an important challenge. Two approaches were investigated. The first involved the formation of a 4-phthalimidocoumarin, aromatisation and hydrolysis of which was expected to lead to the 4-hydroxycoumarin target. The second, a variation of the first, involved the use of 4-(chrolomethyl)coumarin intermediates. Unfortunately, while various intermediates were prepared and characterised, neither approach led ultimately to the desired targets. N-substituted borneol-10-sulfonamides were constructed from camphor-10- sulfonyl chloride as chiral Baylis-Hillman reaction sites. In a preliminary study, however, none of the N-substituted borneol-10-sulfonamides exhibited Baylis-Hillman catalytic activity.
- Full Text:
- Date Issued: 2015
Counsellors’ talk about their understanding of, and practices in response to, intimate partner violence during pregnancy: a narrative-discursive analytic study.
- Authors: Fleischack, Anne
- Date: 2015
- Subjects: Intimate partner violence -- South Africa , Intimate partner violence -- Psychological aspects , Abused women -- Counseling of , Pregnant women -- South Africa -- Abuse of , Pregnant women -- Counseling of
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3255 , http://hdl.handle.net/10962/d1016391
- Description: South Africa is a very violent society, where violence is often used as a social resource to maintain control and establish authority. Global and local research suggests that there is a high prevalence of intimate partner violence (IPV), a facet of this violence, although little research has been conducted into the effects of IPV during pregnancy in the South African non-governmental organisation (NGO) context. NGOs globally and in South Africa have attempted to address IPV and IPV during pregnancy by providing services that aim to assist (largely female) clients emotionally and logistically. In light of this phenomenon, this qualitative study presents data generated through the use of a lightly-structured narrative interview schedule. The interviews were conducted over three sessions with eight counsellors, all based at two NGOs in South Africa and experienced in counselling women who have suffered IPV and IPV during pregnancy. This study used Taylor and Littleton’s (2006) narrative-discursive analytical lens, infused with theoretical insights from Foucault about power, discourse and narrative in order to identify the discursive resources that shape the narratives that the counsellors shared in the interviews and how these translate into subject positions and (gendered) power relations of the men and women about whom they speak. Six discursive resources emerged from the narratives, namely a discourse of ‘traditional “African” culture’, ‘patriarchal masculinity’, ‘nurturing femininity’, ‘female victimhood’, ‘female survivorhood’ and ‘human rights’. These informed the three main narratives that emerged: narratives about IPV in general, IPV during pregnancy, and the counsellors’ narratives about their intervention strategies. Within these narratives (and the micro-narratives which comprised them), men were largely positioned as subscribing to violent patriarchal behaviour whilst women were mostly positioned as nurturing and victims of this violence. The counsellors also constructed women as largely ignorant of their options about IPV and IPV during pregnancy; they constructed these phenomena as problems that require intervention and identified a number of factors that indicate what successful IPV interventions should entail. In reflecting upon this analysis, this study also aimed to address the questions of what is achieved or gained by using these narratives and discursive resources, what the significance or consequences are of constructing and using these particular narratives and discourses and whether different narratives or discourses would have been possible. Recommendations for further research includes incorporating more sites as well as interviewing perpetrators and IPV survivors themselves, perhaps in their home language where relevant rather than English, to gain a broader and more faceted understanding of the dynamics surrounding IPV during pregnancy. A recommendation for practice in intervention against IPV during pregnancy is to introduce more holistic/systemic intervention strategies and working with communities to address this issue.
- Full Text:
- Date Issued: 2015
- Authors: Fleischack, Anne
- Date: 2015
- Subjects: Intimate partner violence -- South Africa , Intimate partner violence -- Psychological aspects , Abused women -- Counseling of , Pregnant women -- South Africa -- Abuse of , Pregnant women -- Counseling of
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3255 , http://hdl.handle.net/10962/d1016391
- Description: South Africa is a very violent society, where violence is often used as a social resource to maintain control and establish authority. Global and local research suggests that there is a high prevalence of intimate partner violence (IPV), a facet of this violence, although little research has been conducted into the effects of IPV during pregnancy in the South African non-governmental organisation (NGO) context. NGOs globally and in South Africa have attempted to address IPV and IPV during pregnancy by providing services that aim to assist (largely female) clients emotionally and logistically. In light of this phenomenon, this qualitative study presents data generated through the use of a lightly-structured narrative interview schedule. The interviews were conducted over three sessions with eight counsellors, all based at two NGOs in South Africa and experienced in counselling women who have suffered IPV and IPV during pregnancy. This study used Taylor and Littleton’s (2006) narrative-discursive analytical lens, infused with theoretical insights from Foucault about power, discourse and narrative in order to identify the discursive resources that shape the narratives that the counsellors shared in the interviews and how these translate into subject positions and (gendered) power relations of the men and women about whom they speak. Six discursive resources emerged from the narratives, namely a discourse of ‘traditional “African” culture’, ‘patriarchal masculinity’, ‘nurturing femininity’, ‘female victimhood’, ‘female survivorhood’ and ‘human rights’. These informed the three main narratives that emerged: narratives about IPV in general, IPV during pregnancy, and the counsellors’ narratives about their intervention strategies. Within these narratives (and the micro-narratives which comprised them), men were largely positioned as subscribing to violent patriarchal behaviour whilst women were mostly positioned as nurturing and victims of this violence. The counsellors also constructed women as largely ignorant of their options about IPV and IPV during pregnancy; they constructed these phenomena as problems that require intervention and identified a number of factors that indicate what successful IPV interventions should entail. In reflecting upon this analysis, this study also aimed to address the questions of what is achieved or gained by using these narratives and discursive resources, what the significance or consequences are of constructing and using these particular narratives and discourses and whether different narratives or discourses would have been possible. Recommendations for further research includes incorporating more sites as well as interviewing perpetrators and IPV survivors themselves, perhaps in their home language where relevant rather than English, to gain a broader and more faceted understanding of the dynamics surrounding IPV during pregnancy. A recommendation for practice in intervention against IPV during pregnancy is to introduce more holistic/systemic intervention strategies and working with communities to address this issue.
- Full Text:
- Date Issued: 2015
Contributions to the study of a class of optimal control problems on the orthogonal groups SO(3) and SO(4)
- Authors: Adams, Ross Montague
- Date: 2015
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/64826 , vital:28608
- Description: In this thesis we investigate a class of invariant optimal control problems, and their associated quadratic Hamilton-Poisson systems, on the orthogonal groups SO(3) and SO(4). Specifically, we are concerned with the class of left-invariant control affine systems. We begin by classifying all cost-extended systems on SO(3) under cost equivalence. (Cost-extended systems are closely related to optimal control problems.) A classification of all quadratic Hamilton-Poisson systems on the (minus) Lie-Poisson space so(3)*, under affine equivalence, is also obtained. For the normal forms obtained in our classification (of Hamilton-Poisson systems) we investigate the (Lyapunov) stability nature of the equilibria using spectral and energy-Casimir methods. For a subclass of these systems, we obtain analytic expressions for the integral curves of the associated Hamiltonian vector fields in terms of (basic) Jacobi elliptic functions. The explicit relationship between the classification of cost-extended systems on SO(3) and the classification of quadratic Hamilton- Poisson systems on so(3)* is provided. On SO(4), a classification of all left-invariant control affine systems under L-equivalence is obtained. We then determine which of these representatives are controllable, thus obtaining a classification under detached feedback equivalence. We also obtain a partial classification of quadratic Hamilton-Poisson systems on the Lie-Poisson space so(4)*. An investigation of the stability nature of the equilibria for a subclass of these systems is also done. Several illustrative examples of optimal control problems on the orthogonal group SO(3) are provided. More specifically, we consider an optimal control problem corresponding to a representative of our classification (of cost-extended system) for each possible number of control inputs. For each of these problems, we obtain explicit expressions for the extremal trajectories on the homogeneous space S2 by projecting the extremal trajectories on the group SO(3). The examples provided show how our classifications of cost-extended systems and Hamilton-Poisson systems can be used to obtain the optimal controls and the extremal trajectories corresponding to a large class of optimal control problems on SO(3). An example of a four-input optimal control problem on SO(4) is also provided. This example is provided to show how the solutions of certain problems on SO(4) can be related to the solutions of certain optimal control problems on SO(3).
- Full Text:
- Date Issued: 2015
- Authors: Adams, Ross Montague
- Date: 2015
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/64826 , vital:28608
- Description: In this thesis we investigate a class of invariant optimal control problems, and their associated quadratic Hamilton-Poisson systems, on the orthogonal groups SO(3) and SO(4). Specifically, we are concerned with the class of left-invariant control affine systems. We begin by classifying all cost-extended systems on SO(3) under cost equivalence. (Cost-extended systems are closely related to optimal control problems.) A classification of all quadratic Hamilton-Poisson systems on the (minus) Lie-Poisson space so(3)*, under affine equivalence, is also obtained. For the normal forms obtained in our classification (of Hamilton-Poisson systems) we investigate the (Lyapunov) stability nature of the equilibria using spectral and energy-Casimir methods. For a subclass of these systems, we obtain analytic expressions for the integral curves of the associated Hamiltonian vector fields in terms of (basic) Jacobi elliptic functions. The explicit relationship between the classification of cost-extended systems on SO(3) and the classification of quadratic Hamilton- Poisson systems on so(3)* is provided. On SO(4), a classification of all left-invariant control affine systems under L-equivalence is obtained. We then determine which of these representatives are controllable, thus obtaining a classification under detached feedback equivalence. We also obtain a partial classification of quadratic Hamilton-Poisson systems on the Lie-Poisson space so(4)*. An investigation of the stability nature of the equilibria for a subclass of these systems is also done. Several illustrative examples of optimal control problems on the orthogonal group SO(3) are provided. More specifically, we consider an optimal control problem corresponding to a representative of our classification (of cost-extended system) for each possible number of control inputs. For each of these problems, we obtain explicit expressions for the extremal trajectories on the homogeneous space S2 by projecting the extremal trajectories on the group SO(3). The examples provided show how our classifications of cost-extended systems and Hamilton-Poisson systems can be used to obtain the optimal controls and the extremal trajectories corresponding to a large class of optimal control problems on SO(3). An example of a four-input optimal control problem on SO(4) is also provided. This example is provided to show how the solutions of certain problems on SO(4) can be related to the solutions of certain optimal control problems on SO(3).
- Full Text:
- Date Issued: 2015
Comparison between Endothelin, Nitric Oxide and their Association to Blood Pressure and Body Composition in HIV Patients, in Mthatha
- Authors: Zono, Sinethemba
- Date: 2015
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/2909 , vital:43105
- Description: Background: Dysfunction of the vascular endothelium is an early finding in the progression of cardiovascular disease and is closely related to clinical events in patients with obesity and hypertension. Vascular function is mediated by nitric oxide (NO) and endothelin (ET-1) which serve as natural counterparts. The aim of the study was to determine the physiological effects of HIV infection, blood pressure and body composition on the changes of ET-1 and NO and association between ET-1 and NO. Methods and results: This was a descriptive and comparative study. A Quota sample method was used. The study population consisted of 154 participants categorized into the following groups: 57 HIV negative participants (A), 40 HIV positive not on treatment participants and 57 HIV positive on treatment participants. Enzyme immunoassay kit was used for the quantitative determination of ET-1 and Nitrate/nitrite colorimetric assay kit was used for the determination of NO. Anthropometric measurements, body composition were determined. Hemodynamic measurements were also taken into account. Results: Resting metabolism, waist circumference (WC) and hip circumference had low mean levels in both HIV positives groups compared to HIV negative group. On lipid profiles visceral fat (VF), whole fat (WF) had low mean levels but skeletal muscle fat (SMF) showed the highest mean levels in both HIV positive groups. All the blood pressures between HIV groups were on a normal range scale. Mean values of endothelin and nitric oxide are increased in HIV positive not on ART and HIV (+) on ART compared with the HIV negative group. Conclusion: NO, ET-1, ART and HIV itself were associated with the pathogenesis of endothelial dysfunction in persons with HIV infection. Elevated endothelial markers namely ET-1 and NO can lead to improvement of endothelium dependent relaxation to some extent but not completely. Although these markers have deleterious effect on the endothelium but can also serve as up-regulator of hypertension. Key words: HIV-infection, antiretroviral therapy, endothelial dysfunction, Endothelin1 (ET-1), nitric oxide (NO), blood pressures (BPs). , Thesis (MSc) -- Faculty of Health Sciences, 2015
- Full Text:
- Date Issued: 2015
- Authors: Zono, Sinethemba
- Date: 2015
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/2909 , vital:43105
- Description: Background: Dysfunction of the vascular endothelium is an early finding in the progression of cardiovascular disease and is closely related to clinical events in patients with obesity and hypertension. Vascular function is mediated by nitric oxide (NO) and endothelin (ET-1) which serve as natural counterparts. The aim of the study was to determine the physiological effects of HIV infection, blood pressure and body composition on the changes of ET-1 and NO and association between ET-1 and NO. Methods and results: This was a descriptive and comparative study. A Quota sample method was used. The study population consisted of 154 participants categorized into the following groups: 57 HIV negative participants (A), 40 HIV positive not on treatment participants and 57 HIV positive on treatment participants. Enzyme immunoassay kit was used for the quantitative determination of ET-1 and Nitrate/nitrite colorimetric assay kit was used for the determination of NO. Anthropometric measurements, body composition were determined. Hemodynamic measurements were also taken into account. Results: Resting metabolism, waist circumference (WC) and hip circumference had low mean levels in both HIV positives groups compared to HIV negative group. On lipid profiles visceral fat (VF), whole fat (WF) had low mean levels but skeletal muscle fat (SMF) showed the highest mean levels in both HIV positive groups. All the blood pressures between HIV groups were on a normal range scale. Mean values of endothelin and nitric oxide are increased in HIV positive not on ART and HIV (+) on ART compared with the HIV negative group. Conclusion: NO, ET-1, ART and HIV itself were associated with the pathogenesis of endothelial dysfunction in persons with HIV infection. Elevated endothelial markers namely ET-1 and NO can lead to improvement of endothelium dependent relaxation to some extent but not completely. Although these markers have deleterious effect on the endothelium but can also serve as up-regulator of hypertension. Key words: HIV-infection, antiretroviral therapy, endothelial dysfunction, Endothelin1 (ET-1), nitric oxide (NO), blood pressures (BPs). , Thesis (MSc) -- Faculty of Health Sciences, 2015
- Full Text:
- Date Issued: 2015
Lived experiences of professional nurses caring for mechanically ventilated patients
- Authors: Else, Liana
- Date: 2015
- Subjects: Respiratory intensive care , Respiratory therapy , Respirators (Medical equipment) , Artificial respiration
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/8295 , vital:26320
- Description: Critical care nursing is a speciality that continues to evolve and transform. Critical care nurses of the 21st century routinely care for the complex, critically ill patient, integrating sophisticated technology with the accompanying psychosocial challenges and the ethical conflicts associated with critical illness – while, at the same time, addressing the needs and concerns of the family. Providing nursing care in such a dynamic and fast-track unit can pose various challenges for the critical care nurse. Professional nurses are the backbone of any health-care system. The quality of nursing directly affects the patients’ outcomes, and nursing care must therefore be rendered meticulously. Mechanical ventilator support is routinely needed for critically ill adults in these care units and is also a common therapy in sub-acute and long-term care settings. The care of the mechanically ventilated patient is the core of a professional nurse`s practice in the critical care unit. The mechanically ventilated patient presents many challenges for the professional nurse, while the critical care unit poses as a stressful environment for the professional nurse as well as the patient. The objectives of this study therefore were to explore and describe the lived experiences of professional nurses while caring for mechanically ventilated patients, and to develop recommendations to support professional nurses while caring for mechanically ventilated patients. A qualitative, explorative, descriptive and contextual research design was utilised. Data was collected by means of semi-structured interviews and analysed according to the framework provided by Tesch. Purposive sampling was used to select a sample of professional nurses working in a critical care environment. Guba’s model was utilised to verify data and to ensure trustworthiness of the study. Ethical principles were adhered to throughout this research study. With the analysed data, recommendations were to support professional nurses while caring for mechanically ventilated.
- Full Text:
- Date Issued: 2015
- Authors: Else, Liana
- Date: 2015
- Subjects: Respiratory intensive care , Respiratory therapy , Respirators (Medical equipment) , Artificial respiration
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/8295 , vital:26320
- Description: Critical care nursing is a speciality that continues to evolve and transform. Critical care nurses of the 21st century routinely care for the complex, critically ill patient, integrating sophisticated technology with the accompanying psychosocial challenges and the ethical conflicts associated with critical illness – while, at the same time, addressing the needs and concerns of the family. Providing nursing care in such a dynamic and fast-track unit can pose various challenges for the critical care nurse. Professional nurses are the backbone of any health-care system. The quality of nursing directly affects the patients’ outcomes, and nursing care must therefore be rendered meticulously. Mechanical ventilator support is routinely needed for critically ill adults in these care units and is also a common therapy in sub-acute and long-term care settings. The care of the mechanically ventilated patient is the core of a professional nurse`s practice in the critical care unit. The mechanically ventilated patient presents many challenges for the professional nurse, while the critical care unit poses as a stressful environment for the professional nurse as well as the patient. The objectives of this study therefore were to explore and describe the lived experiences of professional nurses while caring for mechanically ventilated patients, and to develop recommendations to support professional nurses while caring for mechanically ventilated patients. A qualitative, explorative, descriptive and contextual research design was utilised. Data was collected by means of semi-structured interviews and analysed according to the framework provided by Tesch. Purposive sampling was used to select a sample of professional nurses working in a critical care environment. Guba’s model was utilised to verify data and to ensure trustworthiness of the study. Ethical principles were adhered to throughout this research study. With the analysed data, recommendations were to support professional nurses while caring for mechanically ventilated.
- Full Text:
- Date Issued: 2015
A comparative study of the in vitro antidiabetic properties, cytotoxicity and mechanism of action of Albuca bracteata and Albuca setosa bulb extracts
- Authors: Odeyemi, Samuel Wale
- Date: 2015
- Subjects: Medicinal plants Herbs -- Therapeutic use Diabetics -- Alternative treatment
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/3154 , vital:28327
- Description: The search for cheap, non toxic and readily available antidiabetic drugs has been a challenge for researchers and the pharmaceutical industries. Diabetes mellitus is a metabolic disease characterized by defects in the synthesis of insulin and/or insensitivity to the action of insulin at the target cells. The disease has been on the increase mostly in developing countries where large proportions of the population have little access to good medical care due to either accessibility or non availability of synthetic drugs. This has led to the use of medicinal plants to treat diabetes because it is safe, cheap and with few side effects. There is little scientific evidence on the dosages, active compounds, mechanisms of action and toxicity of these traditionally used plants. Two of the most frequently used plants; Albuca setosa and Albuca bracteata were investigated in this study. The qualitative analysis of different extractions of these plants revealed the presence of phenolics, alkaloids, tannins and saponins. The antioxidant properties of aqueous, acetone and methanollic extracts of Albuca setosa and Albuca bracteata were investigated using models such as Diphenyl-1-Picrylhydrazyl (DPPH), 2, 2’-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), Ferric ion reducing antioxidant potential (FRAP), Nitric Oxide and Hydrogen Peroxide (H2O2). Both plants revealed inhibitions against DPPH in a concentration - dependent manner with Albuca setosa (0.330 mg/ml) showing higher activity than Albuca bracteata (0.647 mg/ml) determined from the IC50. The aqueous extract of Albuca setosa showed a higher inhibition against DPPH radical compared to the Albuca bracteata aqueous extract at all concentrations investigated. The isolated saponins from Albuca bracteata had a higher DPPH scavenging activity than the crude methanolic extract of the plant in a concentration - dependent manner but are significantly different from each other at 0.4, 0.6 and 1.0 mg/ml only. The IC50 of the saponins was also observed to be higher than the crude extracts and standards.The Albuca setosa aqueous extract showed a higher percentage inhibition of ABTS radicals than Albuca bracteata at all the concentrations investigated. Overall, the Albuca setosa aqueous extract (0.0809 mg/ml) showed maximum activity against ABTS radicals. The iron reducing power was significantly higher (P < 0.05) in the methanolic extract of both plants compared to the aqueous counterpart. Overall, the Albuca bracteata aqueous extract (0.344 mg/ml) showed maximum activity as indicated by the IC50. The aqueous extracts of both plants also revealed percentage inhibitions in a concentration - dependent manner against NO2. The aqueous extract of Albuca bracteata bulb was more active against nitric oxide and hydrogen peroxide inhibition. In this study, the cytotoxicity of the extracts was evaluated at a high dose of 100 μg/ml on Chang liver cells and determined using MTT, crystal violet, glucose consumption, lactate production and lactate dehydrogenase release and FRAP. The aqueous extracts of both Albuca setosa and Albuca bracteata were non-toxic on Chang liver cells at the concentrations investigated. The MTT revealed that the aqueous extract of Albuca setosa bulb had the optimum cell viability of 108.09 percent while the acetonic extract of Albuca bracteata showed the least cell viability (37.72 percent) compared with the control. The crystal violet test also revealed the acetone extract of Albuca bracteata to have the least percentage of cell viability at 31.47 percent, while the aqueous extract of Albuca setosa showed the maximum cell viability at 112.5 percent. The aqueous extracts of both plants showed higher percentage cell density on the second day of incubation from the proliferation assay. All the tested samples were observed to consume more glucose than the blank except for the methanollic and acetone extracts of Albuca bracteata bulb. The aqueous and methanolic extracts of Albuca setosa bulbs produced the highest lactate with 120.2 μg/ml and 113.7 μg/ml respectively. The acetone extracts of both Albuca setosa and Albuca bracteata revealed toxicity with a higher lactate dehydrogenase release compared to the control.
- Full Text:
- Date Issued: 2015
- Authors: Odeyemi, Samuel Wale
- Date: 2015
- Subjects: Medicinal plants Herbs -- Therapeutic use Diabetics -- Alternative treatment
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/3154 , vital:28327
- Description: The search for cheap, non toxic and readily available antidiabetic drugs has been a challenge for researchers and the pharmaceutical industries. Diabetes mellitus is a metabolic disease characterized by defects in the synthesis of insulin and/or insensitivity to the action of insulin at the target cells. The disease has been on the increase mostly in developing countries where large proportions of the population have little access to good medical care due to either accessibility or non availability of synthetic drugs. This has led to the use of medicinal plants to treat diabetes because it is safe, cheap and with few side effects. There is little scientific evidence on the dosages, active compounds, mechanisms of action and toxicity of these traditionally used plants. Two of the most frequently used plants; Albuca setosa and Albuca bracteata were investigated in this study. The qualitative analysis of different extractions of these plants revealed the presence of phenolics, alkaloids, tannins and saponins. The antioxidant properties of aqueous, acetone and methanollic extracts of Albuca setosa and Albuca bracteata were investigated using models such as Diphenyl-1-Picrylhydrazyl (DPPH), 2, 2’-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), Ferric ion reducing antioxidant potential (FRAP), Nitric Oxide and Hydrogen Peroxide (H2O2). Both plants revealed inhibitions against DPPH in a concentration - dependent manner with Albuca setosa (0.330 mg/ml) showing higher activity than Albuca bracteata (0.647 mg/ml) determined from the IC50. The aqueous extract of Albuca setosa showed a higher inhibition against DPPH radical compared to the Albuca bracteata aqueous extract at all concentrations investigated. The isolated saponins from Albuca bracteata had a higher DPPH scavenging activity than the crude methanolic extract of the plant in a concentration - dependent manner but are significantly different from each other at 0.4, 0.6 and 1.0 mg/ml only. The IC50 of the saponins was also observed to be higher than the crude extracts and standards.The Albuca setosa aqueous extract showed a higher percentage inhibition of ABTS radicals than Albuca bracteata at all the concentrations investigated. Overall, the Albuca setosa aqueous extract (0.0809 mg/ml) showed maximum activity against ABTS radicals. The iron reducing power was significantly higher (P < 0.05) in the methanolic extract of both plants compared to the aqueous counterpart. Overall, the Albuca bracteata aqueous extract (0.344 mg/ml) showed maximum activity as indicated by the IC50. The aqueous extracts of both plants also revealed percentage inhibitions in a concentration - dependent manner against NO2. The aqueous extract of Albuca bracteata bulb was more active against nitric oxide and hydrogen peroxide inhibition. In this study, the cytotoxicity of the extracts was evaluated at a high dose of 100 μg/ml on Chang liver cells and determined using MTT, crystal violet, glucose consumption, lactate production and lactate dehydrogenase release and FRAP. The aqueous extracts of both Albuca setosa and Albuca bracteata were non-toxic on Chang liver cells at the concentrations investigated. The MTT revealed that the aqueous extract of Albuca setosa bulb had the optimum cell viability of 108.09 percent while the acetonic extract of Albuca bracteata showed the least cell viability (37.72 percent) compared with the control. The crystal violet test also revealed the acetone extract of Albuca bracteata to have the least percentage of cell viability at 31.47 percent, while the aqueous extract of Albuca setosa showed the maximum cell viability at 112.5 percent. The aqueous extracts of both plants showed higher percentage cell density on the second day of incubation from the proliferation assay. All the tested samples were observed to consume more glucose than the blank except for the methanollic and acetone extracts of Albuca bracteata bulb. The aqueous and methanolic extracts of Albuca setosa bulbs produced the highest lactate with 120.2 μg/ml and 113.7 μg/ml respectively. The acetone extracts of both Albuca setosa and Albuca bracteata revealed toxicity with a higher lactate dehydrogenase release compared to the control.
- Full Text:
- Date Issued: 2015
An exploration of the effects of mindfulness on people with an HIV positive diagnosis living in the Eastern Cape, South Africa
- Authors: McIntyre, Tracy-Leigh
- Date: 2015
- Subjects: Mindfulness-based cognitive therapy Stress management HIV infections
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/9903 , vital:26631
- Description: Mindfulness research is growing considerably, though there is very little research in the area of HIV and mindfulness. This study explored and described the experience of a sample of HIV positive people, before and after an 8 week Mindfulness Based Stress Reduction (MBSR) programme, to ascertain whether mindfulness can positively impact the CD4 count of the participants, with the consequent improvement to their immune systems. The incidence of depression, anxiety and stress levels were also explored. The research sample consisted of 17 participants recruited from a local hospital clinic. Purposive sampling was used to source participants. The mixed method approach of data gathering was made up of a pre-test post-test battery of questionnaires and blood tests. Mindfulness levels were assessed with the Five Facet Mindfulness Questionnaire (FFMQ) and Mindfulness Attention Awareness Scale (MAAS) at 3 intervals, while depression, anxiety and stress were assessed by means of the Depression Anxiety Stress Scale (DASS-21). Key findings included the following: the drop out rate for this population group was large, mindfulness practices do not always have a positive effect on immune functioning when there are other confounding variables at play, all participants reported they benefited from the 8 week MBSR course, though their results did not always indicate this. In conclusion it is proposed that mindfulness is potentially beneficial.
- Full Text:
- Date Issued: 2015
- Authors: McIntyre, Tracy-Leigh
- Date: 2015
- Subjects: Mindfulness-based cognitive therapy Stress management HIV infections
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/9903 , vital:26631
- Description: Mindfulness research is growing considerably, though there is very little research in the area of HIV and mindfulness. This study explored and described the experience of a sample of HIV positive people, before and after an 8 week Mindfulness Based Stress Reduction (MBSR) programme, to ascertain whether mindfulness can positively impact the CD4 count of the participants, with the consequent improvement to their immune systems. The incidence of depression, anxiety and stress levels were also explored. The research sample consisted of 17 participants recruited from a local hospital clinic. Purposive sampling was used to source participants. The mixed method approach of data gathering was made up of a pre-test post-test battery of questionnaires and blood tests. Mindfulness levels were assessed with the Five Facet Mindfulness Questionnaire (FFMQ) and Mindfulness Attention Awareness Scale (MAAS) at 3 intervals, while depression, anxiety and stress were assessed by means of the Depression Anxiety Stress Scale (DASS-21). Key findings included the following: the drop out rate for this population group was large, mindfulness practices do not always have a positive effect on immune functioning when there are other confounding variables at play, all participants reported they benefited from the 8 week MBSR course, though their results did not always indicate this. In conclusion it is proposed that mindfulness is potentially beneficial.
- Full Text:
- Date Issued: 2015
A geochemical and morphological investigation of placer gold grains from the southern Seward Peninsula, Alaska : implications for source and transport mechanisms
- Gauntlett, Ernest John Herbert
- Authors: Gauntlett, Ernest John Herbert
- Date: 2015
- Subjects: Placer deposits -- Alaska -- Seward Peninsula , Gold alloys , Gold mines and mining -- Alaska -- Seward Peninsula , Geochemical surveys -- Alaska -- Seward Peninsula , Trace elements -- Alaska -- Seward Peninsula , Drift -- Alaska -- Seward Peninsula , Gold -- Standards of fineness
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5085 , http://hdl.handle.net/10962/d1018202
- Description: [Partial abstract]: This study presents the first detailed geochemical and morphological characterisation of gold grains from the southern Seward Peninsula, Alaska, a region with significant historical and on-going placer gold mining. Quantitative Au, Ag, Hg, and Cu data are presented for gold grains from eleven sites. Additionally, quantitative Te, W, As, and Sb trace element data are presented for gold grains from ten of the eleven sites. Although it is acknowledged that quantitative trace element analysis of gold grains is a relatively new endeavour, the limited trace element data obtained in this study suggest that trace element analysis could be useful for characterising gold sources on the southern Seward Peninsula. Major and minor element geochemical profiling is sufficient at differentiating between sites from regional provenance systems but insufficient at differentiating between sites within a single system. Differentiating among sites within a single system will likely require microchemical analysis of mineral inclusions and analysis of trace element signatures.
- Full Text:
- Date Issued: 2015
- Authors: Gauntlett, Ernest John Herbert
- Date: 2015
- Subjects: Placer deposits -- Alaska -- Seward Peninsula , Gold alloys , Gold mines and mining -- Alaska -- Seward Peninsula , Geochemical surveys -- Alaska -- Seward Peninsula , Trace elements -- Alaska -- Seward Peninsula , Drift -- Alaska -- Seward Peninsula , Gold -- Standards of fineness
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5085 , http://hdl.handle.net/10962/d1018202
- Description: [Partial abstract]: This study presents the first detailed geochemical and morphological characterisation of gold grains from the southern Seward Peninsula, Alaska, a region with significant historical and on-going placer gold mining. Quantitative Au, Ag, Hg, and Cu data are presented for gold grains from eleven sites. Additionally, quantitative Te, W, As, and Sb trace element data are presented for gold grains from ten of the eleven sites. Although it is acknowledged that quantitative trace element analysis of gold grains is a relatively new endeavour, the limited trace element data obtained in this study suggest that trace element analysis could be useful for characterising gold sources on the southern Seward Peninsula. Major and minor element geochemical profiling is sufficient at differentiating between sites from regional provenance systems but insufficient at differentiating between sites within a single system. Differentiating among sites within a single system will likely require microchemical analysis of mineral inclusions and analysis of trace element signatures.
- Full Text:
- Date Issued: 2015
A discourse of disconnect : young people from the Eastern Cape talk about the failure of adult communications to provide habitable sexual subject positions
- Jearey-Graham, Nicola, Macleod, Catriona I
- Authors: Jearey-Graham, Nicola , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: Article
- Identifier: vital:6308 , http://hdl.handle.net/10962/d1018864 , http://0-hdl.handle.net.wam.seals.ac.za/10520/EJC171669
- Description: Face-to-face adult communication with young people about sexuality is, for the most part, assigned to two main groups of people: educators tasked with teaching schoolbased sexuality education that is provided as part of the compulsory Life Orientation (LO) learning area, and parents. In this paper, we report on a study conducted with Further Education and Training College students in an Eastern Cape town. Using a discursive psychology lens, we analysed data from, first, a written question on what participants remember being taught about sexuality in LO classes and, second, focus group discussions held with mixed and same-sex groups. Discussions were structured around the sexualities of high school learners and the LO sexuality education that participants received at high school. We highlight participants’ common deployment of a ‘discourse of disconnect’ in their talk. In this discourse, the messages of ‘risk’ and ‘responsibility’ contained in adult face-to-face communications, by both parents and LO teachers, are depicted as being delivered through inadequate or nonrelational styles of communication, and as largely irrelevant to participants’ lives. Neither of these sources of communication was seen as understanding the realities of youth sexualities or as creating habitable or performable sexual subject positions. The dominance of this ‘discourse of disconnect’ has implications for how sexuality education and parent communication interventions are conducted.
- Full Text:
- Date Issued: 2015
- Authors: Jearey-Graham, Nicola , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: Article
- Identifier: vital:6308 , http://hdl.handle.net/10962/d1018864 , http://0-hdl.handle.net.wam.seals.ac.za/10520/EJC171669
- Description: Face-to-face adult communication with young people about sexuality is, for the most part, assigned to two main groups of people: educators tasked with teaching schoolbased sexuality education that is provided as part of the compulsory Life Orientation (LO) learning area, and parents. In this paper, we report on a study conducted with Further Education and Training College students in an Eastern Cape town. Using a discursive psychology lens, we analysed data from, first, a written question on what participants remember being taught about sexuality in LO classes and, second, focus group discussions held with mixed and same-sex groups. Discussions were structured around the sexualities of high school learners and the LO sexuality education that participants received at high school. We highlight participants’ common deployment of a ‘discourse of disconnect’ in their talk. In this discourse, the messages of ‘risk’ and ‘responsibility’ contained in adult face-to-face communications, by both parents and LO teachers, are depicted as being delivered through inadequate or nonrelational styles of communication, and as largely irrelevant to participants’ lives. Neither of these sources of communication was seen as understanding the realities of youth sexualities or as creating habitable or performable sexual subject positions. The dominance of this ‘discourse of disconnect’ has implications for how sexuality education and parent communication interventions are conducted.
- Full Text:
- Date Issued: 2015