In silico characterization of plasmodial transketolases as potential malaria drug target
- Authors: Boateng, Rita Afriyie
- Date: 2018
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/63540 , vital:28433
- Description: Expected release date-April 2019
- Full Text:
- Date Issued: 2018
- Authors: Boateng, Rita Afriyie
- Date: 2018
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/63540 , vital:28433
- Description: Expected release date-April 2019
- Full Text:
- Date Issued: 2018
Diversified computational approaches for the identification of orthosteric drugs, allosteric modulators and unveiling drug resistance mechanisms: application to infectious diseases
- Authors: Boateng, Rita Afriyie
- Date: 2022-04-08
- Subjects: Uncatalogued
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/234173 , vital:50169
- Description: Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-04-08
- Authors: Boateng, Rita Afriyie
- Date: 2022-04-08
- Subjects: Uncatalogued
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/234173 , vital:50169
- Description: Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-04-08
Margaret, the daughter of Rita Levey
- Subjects: Class reunions -- South Africa -- Grahamstown -- Photographs Grahamstown Teachers' Training College (South Africa) -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/28359 , vital:23641 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , PIC/A 2897_117
- Description: Photograph of Margaret, the daughter of Rita Levey , Leila Kerr (Linington) (Donor)
- Full Text: false
- Subjects: Class reunions -- South Africa -- Grahamstown -- Photographs Grahamstown Teachers' Training College (South Africa) -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/28359 , vital:23641 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , PIC/A 2897_117
- Description: Photograph of Margaret, the daughter of Rita Levey , Leila Kerr (Linington) (Donor)
- Full Text: false
Rhodes University 2018 Graduation Ceremony: 1820 Settlers' National Monument, Thursday, 5 April at 14:30
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64579 , vital:28562 , https://www.youtube.com/watch?v=W249OFk3Orc , https://www.youtube.com/watch?v=57N4HWWgao8 , https://www.youtube.com/watch?v=Xo-GsMBjaGQ
- Description: Rhodes University 2018 Graduation Programme, 5 April at 14:30: Bachelor’s: Bachelor of Pharmacy, Bachelor of Laws. Honours: Bachelor of Commerce Honours, Bachelor of Economics Honours. Postgrad Diplomas: Postgraduate Diploma in Accountancy, Postgraduate Diploma in Taxation. Master’s: Master of Science, Master of Science (Pharmacy), Master of Pharmacy, Master of Laws. Doctorate: Doctor of Pharmacy, PhD in Pharmacy, PhD in Law.
- Full Text:
- Date Issued: 2018
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64579 , vital:28562 , https://www.youtube.com/watch?v=W249OFk3Orc , https://www.youtube.com/watch?v=57N4HWWgao8 , https://www.youtube.com/watch?v=Xo-GsMBjaGQ
- Description: Rhodes University 2018 Graduation Programme, 5 April at 14:30: Bachelor’s: Bachelor of Pharmacy, Bachelor of Laws. Honours: Bachelor of Commerce Honours, Bachelor of Economics Honours. Postgrad Diplomas: Postgraduate Diploma in Accountancy, Postgraduate Diploma in Taxation. Master’s: Master of Science, Master of Science (Pharmacy), Master of Pharmacy, Master of Laws. Doctorate: Doctor of Pharmacy, PhD in Pharmacy, PhD in Law.
- Full Text:
- Date Issued: 2018
The representation of women's reproductive rights in the American feminist blogosphere: an analysis of the debate around women's reproductive rights and abortion legislation in response to the reformation of the United States health care system in 2009/10
- Authors: Yelverton, Brittany
- Date: 2010
- Subjects: Abortion -- Law and legislation -- United States Reproductive rights -- Law and legislation -- United States Fertility -- Law and legislation -- United States Feminism Blogs -- United States Health care reform -- United States -- 21st century Women -- Blogs -- United States Social change -- United States Discourse analysis Feministing Jezebel
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3494 , http://hdl.handle.net/10962/d1002949
- Description: This study investigates the representation of women's reproductive rights in the feminist blogopshere during 2009/10 United States health care reform. Focusing on two purposively selected feminist blogsites - Feministing and Jezebel- it critically examines the discursive and rhetorical strategies employed by feminist bloggers to contest the erosion of women's reproductive rights as proposed in health care reform legislation. While the reformation of the U.S. health care system was a lengthy process, my analysis is confined to feminist blog posts published in November 2009, December 2009 and March 2010. These three months have been designated as they are roughly representative of three pivotal stages in health care reform: the drafting of the House of Representatives health care reform bill and Stupak Amendment in November 2009, the creation of the Senate health care bill inclusive of the Nelson compromise in December 2009, and the passage of the finalised health care reform bill, the Patient Protection and Affordable Care Act and supplementary executive order, in March 2010. This study is informed by feminist poststructuralist theory and Foucault's conceptions of discourse and power - an appropriate framework for identifying and analysing the unequal power relations that exist between men and women in patriarchal societies. Foucault conceives of discourse as both socially constituted and constitutive and contends that through the constitution of knowledge, discourses designate acceptable ways of talking, writing, and behaving, while simultaneously restricting and prohibiting alternatives, thereby granting power and authority to specific discourses. However, Foucault also stresses the multi-directionality of power and asserts that though hegemonic discourses are privileged over others, power lays in discursive practice at all social sites; hence the socially and politically transformative power of contesting discourses. Critical discourse analysis is informed by this critical theory of language and regards the use of language as a form of social practice located within its specific historical context. Therefore, it is through engaging in the struggle over meaning and producing different 'truths' through the reappropriation of language that the possibility of social change exists. Employing narrative, linguistic and rhetorical analysis, this study identifies the discursive strategies and tactics utilised by feminist bloggers to combat and contest anti-choice health care legislation. The study further seeks to determine how arguments supportive of women's reproductive rights are framed and how feminist discourses are privileged while patriarchal discourse is contested. Drawing on public sphere theory, I argue that the feminist blogosphere constitutes a counter-public which facili tates the articulation and circulation of marginalised and counter-discourses. I conclude this study by examining the feminist blogopshere's role in promoting political change and transformation through alternative representations of women and their reproductive rights.
- Full Text:
- Date Issued: 2010
- Authors: Yelverton, Brittany
- Date: 2010
- Subjects: Abortion -- Law and legislation -- United States Reproductive rights -- Law and legislation -- United States Fertility -- Law and legislation -- United States Feminism Blogs -- United States Health care reform -- United States -- 21st century Women -- Blogs -- United States Social change -- United States Discourse analysis Feministing Jezebel
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3494 , http://hdl.handle.net/10962/d1002949
- Description: This study investigates the representation of women's reproductive rights in the feminist blogopshere during 2009/10 United States health care reform. Focusing on two purposively selected feminist blogsites - Feministing and Jezebel- it critically examines the discursive and rhetorical strategies employed by feminist bloggers to contest the erosion of women's reproductive rights as proposed in health care reform legislation. While the reformation of the U.S. health care system was a lengthy process, my analysis is confined to feminist blog posts published in November 2009, December 2009 and March 2010. These three months have been designated as they are roughly representative of three pivotal stages in health care reform: the drafting of the House of Representatives health care reform bill and Stupak Amendment in November 2009, the creation of the Senate health care bill inclusive of the Nelson compromise in December 2009, and the passage of the finalised health care reform bill, the Patient Protection and Affordable Care Act and supplementary executive order, in March 2010. This study is informed by feminist poststructuralist theory and Foucault's conceptions of discourse and power - an appropriate framework for identifying and analysing the unequal power relations that exist between men and women in patriarchal societies. Foucault conceives of discourse as both socially constituted and constitutive and contends that through the constitution of knowledge, discourses designate acceptable ways of talking, writing, and behaving, while simultaneously restricting and prohibiting alternatives, thereby granting power and authority to specific discourses. However, Foucault also stresses the multi-directionality of power and asserts that though hegemonic discourses are privileged over others, power lays in discursive practice at all social sites; hence the socially and politically transformative power of contesting discourses. Critical discourse analysis is informed by this critical theory of language and regards the use of language as a form of social practice located within its specific historical context. Therefore, it is through engaging in the struggle over meaning and producing different 'truths' through the reappropriation of language that the possibility of social change exists. Employing narrative, linguistic and rhetorical analysis, this study identifies the discursive strategies and tactics utilised by feminist bloggers to combat and contest anti-choice health care legislation. The study further seeks to determine how arguments supportive of women's reproductive rights are framed and how feminist discourses are privileged while patriarchal discourse is contested. Drawing on public sphere theory, I argue that the feminist blogosphere constitutes a counter-public which facili tates the articulation and circulation of marginalised and counter-discourses. I conclude this study by examining the feminist blogopshere's role in promoting political change and transformation through alternative representations of women and their reproductive rights.
- Full Text:
- Date Issued: 2010
A case-study of principal succession : the experience of a high school principal and staff
- Authors: Dowding, Susan Patricia
- Date: 1997
- Subjects: Educational leadership School principals -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1440 , http://hdl.handle.net/10962/d1003321
- Description: This is a study of a principal succession In a non-racial, multicultural High-School in the North West Province of South Africa, formerly the independent homeland known as "Bophuthatswana". I was employed at the school at the time and am, therefore, a complete member-researcher. I use a qualitative research approach which relies mostly on in-depth interviews, individually and in groups. I chose my sample by administering a short biographical questionnaire. I have sought to establish "what is happening?" in the succession process by reporting the insights and experiences of a staff and its new principal. While I use the stage frameworks of more traditional researchers in succession to provide a coherent structure for my analysis, I use the organisational socialisation perspective extensively to analyse the insights provided by the staff and principal. Unlike other principal succession studies, I include the insights of both the principal and the staff. The organisational socialisation approach emphasises that succession is an interactive, multidirectional process. My study reinforces many of the observations of other researchers in leadership succession, whether in business or Education. However, two elements of succession emerge which appear to be unique in terms of other succession literature. These elements include the impact of socio-political events and what I call "ethno-cultural" aspects on the succession socialisation process. I provide examples of the influence these factors exert in this principal succession. This study is therefore of potential significance to administrators in both Education and business in the South African context where there are significant changes taking place in the power structures and ethnic makeup of relevant organisations. I also identify a number of areas for further research.
- Full Text:
- Date Issued: 1997
- Authors: Dowding, Susan Patricia
- Date: 1997
- Subjects: Educational leadership School principals -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1440 , http://hdl.handle.net/10962/d1003321
- Description: This is a study of a principal succession In a non-racial, multicultural High-School in the North West Province of South Africa, formerly the independent homeland known as "Bophuthatswana". I was employed at the school at the time and am, therefore, a complete member-researcher. I use a qualitative research approach which relies mostly on in-depth interviews, individually and in groups. I chose my sample by administering a short biographical questionnaire. I have sought to establish "what is happening?" in the succession process by reporting the insights and experiences of a staff and its new principal. While I use the stage frameworks of more traditional researchers in succession to provide a coherent structure for my analysis, I use the organisational socialisation perspective extensively to analyse the insights provided by the staff and principal. Unlike other principal succession studies, I include the insights of both the principal and the staff. The organisational socialisation approach emphasises that succession is an interactive, multidirectional process. My study reinforces many of the observations of other researchers in leadership succession, whether in business or Education. However, two elements of succession emerge which appear to be unique in terms of other succession literature. These elements include the impact of socio-political events and what I call "ethno-cultural" aspects on the succession socialisation process. I provide examples of the influence these factors exert in this principal succession. This study is therefore of potential significance to administrators in both Education and business in the South African context where there are significant changes taking place in the power structures and ethnic makeup of relevant organisations. I also identify a number of areas for further research.
- Full Text:
- Date Issued: 1997
The Brotherhood of Breath
- Authors: Plougastel, Yann
- Language: French
- Type: Article
- Identifier: vital:13635 , http://hdl.handle.net/10962/d1012522
- Description: Photocopied article from the French newspaper L'Evénement du Jeudi about Chris McGregor and the Brotherhood of Breath and the release of their last recording "Country Cooking". There is also a picture of Chris McGregor playing flute with this article.
- Full Text:
- Authors: Plougastel, Yann
- Language: French
- Type: Article
- Identifier: vital:13635 , http://hdl.handle.net/10962/d1012522
- Description: Photocopied article from the French newspaper L'Evénement du Jeudi about Chris McGregor and the Brotherhood of Breath and the release of their last recording "Country Cooking". There is also a picture of Chris McGregor playing flute with this article.
- Full Text:
Determining the unbinding events and conserved motions associated with the pyrazinamide release due to resistance mutations of Mycobacterium tuberculosis pyrazinamidase:
- Amamuddy, Olivier S, Musyoka, Thommas M, Boateng, Rita A, Zabo, Sophakama, Tastan Bishop, Özlem
- Authors: Amamuddy, Olivier S , Musyoka, Thommas M , Boateng, Rita A , Zabo, Sophakama , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148869 , vital:38781 , https://doi.org/10.1016/j.csbj.2020.05.0099
- Description: Pyrazinamide (PZA) is the only first-line antitubercular drug active against latent Mycobacterium tuberculosis (Mtb). It is activated to pyrazinoic acid by the pncA-encoded pyrazinamidase enzyme (PZase). Despite the emergence of PZA drug resistance, the underlying mechanisms of resistance remain unclear. This study investigated part of these mechanisms by modelling a PZA-bound wild type and 82 mutant PZase structures before applying molecular dynamics (MD) with an accurate Fe2+ cofactor coordination geometry.
- Full Text:
- Date Issued: 2020
- Authors: Amamuddy, Olivier S , Musyoka, Thommas M , Boateng, Rita A , Zabo, Sophakama , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148869 , vital:38781 , https://doi.org/10.1016/j.csbj.2020.05.0099
- Description: Pyrazinamide (PZA) is the only first-line antitubercular drug active against latent Mycobacterium tuberculosis (Mtb). It is activated to pyrazinoic acid by the pncA-encoded pyrazinamidase enzyme (PZase). Despite the emergence of PZA drug resistance, the underlying mechanisms of resistance remain unclear. This study investigated part of these mechanisms by modelling a PZA-bound wild type and 82 mutant PZase structures before applying molecular dynamics (MD) with an accurate Fe2+ cofactor coordination geometry.
- Full Text:
- Date Issued: 2020
A psychobiographical study of Robert Nesta “Bob” Marley
- Authors: Willis, Lynn Sherri
- Date: 2017
- Subjects: Developmental psychology , Life cycle, Human -- Psychological aspects Marley, Bob , Psychology -- Biographical methods
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/13480 , vital:27209
- Description: Psychobiography is a qualitative research design used to explore and understand the life story of an individual through the lens of psychological theory. The application of theory is typically done to finished lives of well-known or enigmatic people, and covers the person’s entire lifespan. The aim of the study was to explore and describe the personality development of the Rastafarian reggae musician Bob Marley.To meet this aim the study created a comprehensive picture of Marley’s life within the particular social, economic and historical context in which he lived. Marley’s work was considered influential both during and after his life. His music is listened to by diverse groups of people, and is known internationally. Marley’s personality was explored by applying Eric Berne’s theory of Transactional Analysis (TA) to his life story. Data was collected and analyzed using a strategy consisting of three steps, namely, data reduction, data display, and conclusion drawing and verification. Results of the study indicated that TA is a suitable theory for creating insight into the life of this historical figure, and has led to an increased understanding of the application of this psychological theory. Lastly, the study has contributed towards increasing the number of psychobiographical studies conducted in the South African context.
- Full Text:
- Date Issued: 2017
- Authors: Willis, Lynn Sherri
- Date: 2017
- Subjects: Developmental psychology , Life cycle, Human -- Psychological aspects Marley, Bob , Psychology -- Biographical methods
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/13480 , vital:27209
- Description: Psychobiography is a qualitative research design used to explore and understand the life story of an individual through the lens of psychological theory. The application of theory is typically done to finished lives of well-known or enigmatic people, and covers the person’s entire lifespan. The aim of the study was to explore and describe the personality development of the Rastafarian reggae musician Bob Marley.To meet this aim the study created a comprehensive picture of Marley’s life within the particular social, economic and historical context in which he lived. Marley’s work was considered influential both during and after his life. His music is listened to by diverse groups of people, and is known internationally. Marley’s personality was explored by applying Eric Berne’s theory of Transactional Analysis (TA) to his life story. Data was collected and analyzed using a strategy consisting of three steps, namely, data reduction, data display, and conclusion drawing and verification. Results of the study indicated that TA is a suitable theory for creating insight into the life of this historical figure, and has led to an increased understanding of the application of this psychological theory. Lastly, the study has contributed towards increasing the number of psychobiographical studies conducted in the South African context.
- Full Text:
- Date Issued: 2017
The soul of Mozambique: an autoethnographic and performance-based study on the correlation of glabalisation, Chopi people migrations and the reinterpretation of timbila music in Mozambique
- Authors: Bande Júnior, Venâncio
- Date: 2022-10-14
- Subjects: Timbila , Chopi (African people) Mozambique , Music festivals Mozambique , Traditional knowledge , Music and globalization , Modernity , Traditional folk music
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406818 , vital:70310
- Description: This is an autoethnographic and performance-based study on the correlation between indigenous and modern cultures. It discusses the influence of globalisation, modernity, and of the Chopi people migrations to Maputo, the main city of Mozambique and to gold and platinum mines in South Africa, on timbila music. Timbila is both the name of a musical instrument (xylophone) and of a cultural manifestation, practiced by the Chopi people from Mozambique. It is one of the most documented music and dance cultures in Mozambique and was proclaimed as a masterpiece of the oral and immaterial heritage of humanity by UNESCO in 2005. The oldest references by Father Andre Fernandes date from the 16th century. However, the most well-known timbila sources were written and recorded by Hugh Tracey, the founder of the International Library of African Music (ILAM), from 1940s. All these sources were based on traditional timbila music. None refers to contemporary timbila music, which is a mixture of timbila with Western musical instruments. The research is thus based on both historical and is new research to understand the role of the phenomena mentioned above to the reinterpretation of timbila music over the time. Performance based and autoethnography methods were selected because of my role as a pedagogue of the music and culture of timbila, allowing me to express my knowledge on this cultural expression. Literature review and interviews are the two procedures of data collecting employed to get an understanding of the research methods; the phenomena of modernity, globalisation and of the Chopis migration for the searching of better living conditions in Maputo and South Africa; and the approaches of different scholars who have written about timbila. The use of these methods and methodologies, allowed me to conclude that, Chopis migrations, modernity and globalisation has allowed the emergence of a modern version of timbila music; internationalisation and dissemination of this musical expression; and contributes to the extinction of traditional timbila orchestras in Zavala. Despite considerable studies on timbila music and culture, this thesis is important and pioneering, from the perspective of studying the influence of Chopis migrations, globalisation and modernity on timbila and is one of the few sources that approach the contemporary timbila music. , Thesis (MMus) -- Faculty of Humanities, Music and Musicology, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Bande Júnior, Venâncio
- Date: 2022-10-14
- Subjects: Timbila , Chopi (African people) Mozambique , Music festivals Mozambique , Traditional knowledge , Music and globalization , Modernity , Traditional folk music
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406818 , vital:70310
- Description: This is an autoethnographic and performance-based study on the correlation between indigenous and modern cultures. It discusses the influence of globalisation, modernity, and of the Chopi people migrations to Maputo, the main city of Mozambique and to gold and platinum mines in South Africa, on timbila music. Timbila is both the name of a musical instrument (xylophone) and of a cultural manifestation, practiced by the Chopi people from Mozambique. It is one of the most documented music and dance cultures in Mozambique and was proclaimed as a masterpiece of the oral and immaterial heritage of humanity by UNESCO in 2005. The oldest references by Father Andre Fernandes date from the 16th century. However, the most well-known timbila sources were written and recorded by Hugh Tracey, the founder of the International Library of African Music (ILAM), from 1940s. All these sources were based on traditional timbila music. None refers to contemporary timbila music, which is a mixture of timbila with Western musical instruments. The research is thus based on both historical and is new research to understand the role of the phenomena mentioned above to the reinterpretation of timbila music over the time. Performance based and autoethnography methods were selected because of my role as a pedagogue of the music and culture of timbila, allowing me to express my knowledge on this cultural expression. Literature review and interviews are the two procedures of data collecting employed to get an understanding of the research methods; the phenomena of modernity, globalisation and of the Chopis migration for the searching of better living conditions in Maputo and South Africa; and the approaches of different scholars who have written about timbila. The use of these methods and methodologies, allowed me to conclude that, Chopis migrations, modernity and globalisation has allowed the emergence of a modern version of timbila music; internationalisation and dissemination of this musical expression; and contributes to the extinction of traditional timbila orchestras in Zavala. Despite considerable studies on timbila music and culture, this thesis is important and pioneering, from the perspective of studying the influence of Chopis migrations, globalisation and modernity on timbila and is one of the few sources that approach the contemporary timbila music. , Thesis (MMus) -- Faculty of Humanities, Music and Musicology, 2022
- Full Text:
- Date Issued: 2022-10-14
Where dreams become reality: professionalism in flight training in the Eastern Cape
- Authors: Allison, Martin
- Date: 2019
- Subjects: Professional socialization , Flight training -- South Africa , Flight schools -- South Africa -- Case studies , Air pilots -- Training of -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/95376 , vital:31150
- Description: This study explores the construction of the identity of professional pilots through a case study of a flying school in South Africa. Here, a 15-20-month period of intensive study and training of students, fresh from school or college, leads in most cases to the attainment of a Commercial or Airline Transport Pilot’s Licence. The construction of identity is a continuous process and a lifelong project and hence this study can only reflect upon the factors influencing the early stages of a pilot’s career, until the point where the licenced Pilot leaves the Air School and enters full time employment with a commercial undertaking, but it is argued that this is a crucial step in the formation of professional identity, habitus in Bourdieu’s terms. The culture of the air School reflects the military background of the founders of the school and the staff employed in senior positions. The school, which is residential, observes a strict regime of Ground School and Practical Flying Training and a high standard of performance and personal conduct is demanded, both during training and in off duty hours and excessive consumption of alcohol and smoking are discouraged, and drug use absolutely taboo. Progress with training at the school is closely monitored and a disciplined environment maintained by surveillance cameras, house monitors and security guards; in Foucauldian terms, a modern version of the Panopticon, but somewhat less than Goffman’s Total Institution. It was found that the construction of a flying identity for most of the students entering the air school commenced in childhood or early adulthood, through the influence of friends and relatives and they enter the school with the firm intention of becoming Professional pilots. Full participation of the author in the Ground School revealed how professionalization is implemented through the discipline and rigor of the training methods employed. Through mastery of a complex body of theoretical knowledge in the Ground School and the practical skill of learning to fly in a one-on-one relationship with an instructor, the students gain confidence and efficacy which contributes to their self-respect and maturity. The international reputation of the school, confers prestige upon its graduates and they benefit from membership of a profession which commands respect and a high level of income. In large measure, the thesis shows, the success of the School is a function of the founders’ ‘invention of tradition’ focusing on the wartime training school that existed on the site and the many echoes of those times in the (re)construction of its buildings and facilities, continuing in the approach of the multinational that now owns the School.
- Full Text:
- Date Issued: 2019
- Authors: Allison, Martin
- Date: 2019
- Subjects: Professional socialization , Flight training -- South Africa , Flight schools -- South Africa -- Case studies , Air pilots -- Training of -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/95376 , vital:31150
- Description: This study explores the construction of the identity of professional pilots through a case study of a flying school in South Africa. Here, a 15-20-month period of intensive study and training of students, fresh from school or college, leads in most cases to the attainment of a Commercial or Airline Transport Pilot’s Licence. The construction of identity is a continuous process and a lifelong project and hence this study can only reflect upon the factors influencing the early stages of a pilot’s career, until the point where the licenced Pilot leaves the Air School and enters full time employment with a commercial undertaking, but it is argued that this is a crucial step in the formation of professional identity, habitus in Bourdieu’s terms. The culture of the air School reflects the military background of the founders of the school and the staff employed in senior positions. The school, which is residential, observes a strict regime of Ground School and Practical Flying Training and a high standard of performance and personal conduct is demanded, both during training and in off duty hours and excessive consumption of alcohol and smoking are discouraged, and drug use absolutely taboo. Progress with training at the school is closely monitored and a disciplined environment maintained by surveillance cameras, house monitors and security guards; in Foucauldian terms, a modern version of the Panopticon, but somewhat less than Goffman’s Total Institution. It was found that the construction of a flying identity for most of the students entering the air school commenced in childhood or early adulthood, through the influence of friends and relatives and they enter the school with the firm intention of becoming Professional pilots. Full participation of the author in the Ground School revealed how professionalization is implemented through the discipline and rigor of the training methods employed. Through mastery of a complex body of theoretical knowledge in the Ground School and the practical skill of learning to fly in a one-on-one relationship with an instructor, the students gain confidence and efficacy which contributes to their self-respect and maturity. The international reputation of the school, confers prestige upon its graduates and they benefit from membership of a profession which commands respect and a high level of income. In large measure, the thesis shows, the success of the School is a function of the founders’ ‘invention of tradition’ focusing on the wartime training school that existed on the site and the many echoes of those times in the (re)construction of its buildings and facilities, continuing in the approach of the multinational that now owns the School.
- Full Text:
- Date Issued: 2019
In silico identification of natural inhibitory compounds against the Mycobacterium tuberculosis Enzyme Pyrazinamidase using high-throughput virtual screening techniques
- Authors: Kenyon, Thomas
- Date: 2021-10-29
- Subjects: Mycobacterium tuberculosis , Pyrazinamide , Molecular dynamics , High throughput screening (Drug development) , Mutagenesis , South African Natural Compounds database (SANCDB)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192074 , vital:45193
- Description: Tuberculosis (TB) is most commonly a pulmonary infection caused by the bacterium Mycobacterium tuberculosis. With the exception of the COVID-19 pandemic, TB was the most common cause of death due to an infectious disease for a number of years up until 2020. In 2019, 10 million people fell ill with TB worldwide and 1.4 million people died (WHO, 2020a). Additionally, multidrug-resistant TB (MDR-TB) remains a public health crisis and a health security threat. A global total of 206 030 people with multidrug- or rifampicin-resistant TB (MDR/RR-TB) were reported in 2019, a 10% increase from 186 883 in 2018. South Africa is ranked among the 48 high TB burden countries, with an estimated 360 000 people falling ill in 2019, resulting in 58 000 deaths, the majority of which being among people living with HIV. Unlike HIV, however, TB is a curable disease when managed correctly with long durations of antitubercular chemotherapy. Pyrazinamide (PZA) is an important first-line tuberculosis drug unique for its activity against latent TB. PZA is a prodrug, being converted into its active form, pyrazinoic acid (POA) by the Mtb gene pncA, coding for the pyrazinamidase enzyme (PZase). TB resistance to first-line drugs such as PZA is commonly associated with mutations in the pncA/PZase enzyme. This study aimed to identify potential novel inhibitors that bind to the active site of PZase. By making use of molecular docking studies and molecular dynamics (MD) simulations, high throughput virtual screening was performed on 623 compounds from the South African Natural Compounds database (SANCDB; https://sancdb.rubi.ru.ac.za). Ligands that selectively bound to the PZase active site were identified using docking studies, followed by MD simulations to assess ligand-PZase complex stability, Finally, hit compounds identified from the first round of MD simulations were screened again against PZase structures with high confidence point mutations known to infer PZA resistance in order to identify any novel compounds which had inhibitory potential against both WT and mutant forms of the PZase enzyme. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Kenyon, Thomas
- Date: 2021-10-29
- Subjects: Mycobacterium tuberculosis , Pyrazinamide , Molecular dynamics , High throughput screening (Drug development) , Mutagenesis , South African Natural Compounds database (SANCDB)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192074 , vital:45193
- Description: Tuberculosis (TB) is most commonly a pulmonary infection caused by the bacterium Mycobacterium tuberculosis. With the exception of the COVID-19 pandemic, TB was the most common cause of death due to an infectious disease for a number of years up until 2020. In 2019, 10 million people fell ill with TB worldwide and 1.4 million people died (WHO, 2020a). Additionally, multidrug-resistant TB (MDR-TB) remains a public health crisis and a health security threat. A global total of 206 030 people with multidrug- or rifampicin-resistant TB (MDR/RR-TB) were reported in 2019, a 10% increase from 186 883 in 2018. South Africa is ranked among the 48 high TB burden countries, with an estimated 360 000 people falling ill in 2019, resulting in 58 000 deaths, the majority of which being among people living with HIV. Unlike HIV, however, TB is a curable disease when managed correctly with long durations of antitubercular chemotherapy. Pyrazinamide (PZA) is an important first-line tuberculosis drug unique for its activity against latent TB. PZA is a prodrug, being converted into its active form, pyrazinoic acid (POA) by the Mtb gene pncA, coding for the pyrazinamidase enzyme (PZase). TB resistance to first-line drugs such as PZA is commonly associated with mutations in the pncA/PZase enzyme. This study aimed to identify potential novel inhibitors that bind to the active site of PZase. By making use of molecular docking studies and molecular dynamics (MD) simulations, high throughput virtual screening was performed on 623 compounds from the South African Natural Compounds database (SANCDB; https://sancdb.rubi.ru.ac.za). Ligands that selectively bound to the PZase active site were identified using docking studies, followed by MD simulations to assess ligand-PZase complex stability, Finally, hit compounds identified from the first round of MD simulations were screened again against PZase structures with high confidence point mutations known to infer PZA resistance in order to identify any novel compounds which had inhibitory potential against both WT and mutant forms of the PZase enzyme. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2021
- Full Text:
- Date Issued: 2021-10-29
Reaching the isolated through the design of air clinic facility in Moshoeshoe II, Maseru Lesotho pre-hospital care and transport
- Authors: Lesia, Tumelo Emmanuel
- Date: 2016
- Subjects: Medical centers -- Lesotho -- Maseru -- Designs and plans Health facilities -- Lesotho -- Maseru
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/39284 , vital:35071
- Description: The purpose of this research is to develop a design of an Air Clinic Facility, to reach the isolated people in the highlands of Lesotho. This came through the realization of the access barrier created by the mountainous terrain, making it difficult to supply medical care to isolated communities. The aim of this research is to investigate a suitable architectural approach to an air clinic facility as a device that will make reaching the isolated effortless. Emergency healthcare architecture principles have been employed as a remedial strategy to the design. The motive behind this treatise originates from the authors desire to understand the role that architecture can play to solve the accessibility issues facing the uplands. The choice to address the realm of emergency healthcare architecture also originates from the desire to understand the effect that architecture can have on the lives of ordinary people. The main architectural intervention will focus on the process of accessing and using the air clinic facility, whereby a mutually beneficial interaction between the program and the context will be realised.
- Full Text:
- Date Issued: 2016
- Authors: Lesia, Tumelo Emmanuel
- Date: 2016
- Subjects: Medical centers -- Lesotho -- Maseru -- Designs and plans Health facilities -- Lesotho -- Maseru
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/39284 , vital:35071
- Description: The purpose of this research is to develop a design of an Air Clinic Facility, to reach the isolated people in the highlands of Lesotho. This came through the realization of the access barrier created by the mountainous terrain, making it difficult to supply medical care to isolated communities. The aim of this research is to investigate a suitable architectural approach to an air clinic facility as a device that will make reaching the isolated effortless. Emergency healthcare architecture principles have been employed as a remedial strategy to the design. The motive behind this treatise originates from the authors desire to understand the role that architecture can play to solve the accessibility issues facing the uplands. The choice to address the realm of emergency healthcare architecture also originates from the desire to understand the effect that architecture can have on the lives of ordinary people. The main architectural intervention will focus on the process of accessing and using the air clinic facility, whereby a mutually beneficial interaction between the program and the context will be realised.
- Full Text:
- Date Issued: 2016
Our languishing heritage comes home
- Authors: Thomas, Cornelius
- Date: 2001-02-02
- Subjects: Dyani, Johnny Mbizo Johnny Dyani Quartet Jazz musicians -- South Africa Jazz -- South Africa -- History and criticism
- Type: article
- Identifier: http://hdl.handle.net/10962/38037 , vital:24727 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 025
- Description: Photocopied article from the newspaper The Daily Dispatch about Jonny Dyani, a jazz musician , Article from The Daily Dispatch, 2 February 2001 about Johnny Dyani and his music.
- Full Text:
- Date Issued: 2001-02-02
- Authors: Thomas, Cornelius
- Date: 2001-02-02
- Subjects: Dyani, Johnny Mbizo Johnny Dyani Quartet Jazz musicians -- South Africa Jazz -- South Africa -- History and criticism
- Type: article
- Identifier: http://hdl.handle.net/10962/38037 , vital:24727 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 025
- Description: Photocopied article from the newspaper The Daily Dispatch about Jonny Dyani, a jazz musician , Article from The Daily Dispatch, 2 February 2001 about Johnny Dyani and his music.
- Full Text:
- Date Issued: 2001-02-02
The design of a retirement home: bridging the gap for the elderly generation through the design of a retirement complex in the heart of a growing city core located in Walmer, Port Elizabeth
- Authors: Watson, Robin Anthony
- Date: 2016
- Subjects: Adult day care centers -- South Africa -- Port Elizabeth -- Design and construction , Nursing homes -- South Africa -- Port Elizabeth -- Design and construction , Older people -- Dwellings -- South Africa -- Port Elizabeth -- Planning , Old age homes -- South Africa -- Port Elizabeth -- Design and construction
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/39185 , vital:35054
- Description: This treatise has been developed from a combination of a specific programme and site related issues. The project centred around the design of a new retirement complex in Walmer, Port Elizabeth. The specific urban condition is of particular interest as the site is centrally located at a meeting point of three different spatial urban conditions, namely commercial, institutional and suburban residential. The programme developed from the need to develop a new typology of elderly housing for the growing elderly population in Port Elizabeth in order to address the often overlooked issues of the existing typologies. These issues were looked into, leading to the understanding that the existing retirement options available within Port Elizabeth are based on the functional separation of the different levels of care required by the elderly in establishments that are isolated from the greater community and are, in some cases, institutional in nature. However, when looking at models for retirement facilities available within other contexts, it is clear that new and innovated models have been developed which have advantages over these 'traditional' establishments. This treatise aims at developing a retirement model within the suburb of Walmer that supports a variety of unique residential options and comprehensive services that meet the needs of recently retired persons who remain active, as well as frail residents. The identifiable challenge is the establishment of an architectural model that provides its occupants with privacy and identity while allowing them to integrate with their environment and avoids the need to move as they grow older.
- Full Text:
- Date Issued: 2016
- Authors: Watson, Robin Anthony
- Date: 2016
- Subjects: Adult day care centers -- South Africa -- Port Elizabeth -- Design and construction , Nursing homes -- South Africa -- Port Elizabeth -- Design and construction , Older people -- Dwellings -- South Africa -- Port Elizabeth -- Planning , Old age homes -- South Africa -- Port Elizabeth -- Design and construction
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/39185 , vital:35054
- Description: This treatise has been developed from a combination of a specific programme and site related issues. The project centred around the design of a new retirement complex in Walmer, Port Elizabeth. The specific urban condition is of particular interest as the site is centrally located at a meeting point of three different spatial urban conditions, namely commercial, institutional and suburban residential. The programme developed from the need to develop a new typology of elderly housing for the growing elderly population in Port Elizabeth in order to address the often overlooked issues of the existing typologies. These issues were looked into, leading to the understanding that the existing retirement options available within Port Elizabeth are based on the functional separation of the different levels of care required by the elderly in establishments that are isolated from the greater community and are, in some cases, institutional in nature. However, when looking at models for retirement facilities available within other contexts, it is clear that new and innovated models have been developed which have advantages over these 'traditional' establishments. This treatise aims at developing a retirement model within the suburb of Walmer that supports a variety of unique residential options and comprehensive services that meet the needs of recently retired persons who remain active, as well as frail residents. The identifiable challenge is the establishment of an architectural model that provides its occupants with privacy and identity while allowing them to integrate with their environment and avoids the need to move as they grow older.
- Full Text:
- Date Issued: 2016
BBS_2021_03_Obalade.pdf
- Authors: Adelin Kantore
- Identifier: http://hdl.handle.net/11260/7635 , vital:54735
- Full Text:
- Authors: Adelin Kantore
- Identifier: http://hdl.handle.net/11260/7635 , vital:54735
- Full Text:
Customer satisfaction with the guesthouse experience in Ghana
- Authors: Amoah, Felix
- Date: 2016
- Subjects: Consumer satisfaction -- Ghana , Hospitality industry -- Ghana -- Management , Tourism -- Ghana -- Marketing
- Language: English
- Type: Thesis , Doctoral , DTech
- Identifier: http://hdl.handle.net/10948/6073 , vital:21036
- Description: Guesthouse accommodation plays an important role in Ghana’s hospitality industry and was therefore the focus of this study as little research dealing with guesthouses in Ghana could be found. The number of guesthouses in Ghana continues to grow and they thus represent an important alternative to hotels. However, these establishments seem to perform poorly and face several challenges such as lack of managerial knowledge, insufficiently skilled employees, poor interaction with customers, and criticisms of the provision of low quality service. The main reason for undertaking this research was to provide guesthouse managers in Ghana with information that might assist them in making decisions about the experience they offer. Such knowledge could make this type of accommodation more competitive and eventually help the hospitality sector in Ghana attract tourists and grow. It is imperative that guesthouses focus on the experience they offer, because contemporary tourism and hospitality literature suggest that successful businesses require a shift from functional and financial interests to a more profound focus on total experiences which embody emotional aspects. It is thus argued that, if guesthouse managers in Ghana do not know how their guests perceive their guesthouse experience, they might make costly mistakes and allocate resources to aspects that already provide quality and value in a functional sense, instead of those elements perceived as providing quality and value in the total experience. Two dominating concepts, namely experience quality and experience value, formed the basis of the examination of guests’ experience with the guesthouses in Ghana. In addition, the relationships between the experience and satisfaction were also investigated. Four experience quality dimensions, namely hedonics, peace of mind, involvement, and recognition, and seven value dimensions were examined. The experience value dimensions included atmospherics, enjoyment, entertainment, efficiency, excellence, escape, and economic value. A proportional stratified random sampling procedure was followed to select the guesthouses for the study. Thereafter, a structured questionnaire was distributed to the guesthouse guests selected by means of convenience sampling. Five hundred and forty one useable questionnaires were received. The guesthouse guests formed the primary sampling unit for this study. The results of the empirical study showed a strong positive correlation between all the dimensions of experience quality and experience value, while the factor analysis confirmed that all these dimensions loaded on a single factor. Therefore, experience quality and experience value cannot be separated, and the resulting single multi-dimensional factor was subsequently renamed, overall experience. The results also indicated a positive relationship between hedonics, peace of mind, involvement, recognition, atmospherics, enjoyment, entertainment, efficiency, excellence, escape, economic value, and overall satisfaction. The inferentially established rank-order of the dimensions contributing to satisfaction can guide managers when allocating resources. Overall, atmospherics was ranked first, followed by economic value. Escape was the lowest ranked dimension. In addition, it was found that, except for escape, all the experience dimensions were perceived as basic satisfiers. This implies that guests will be dissatisfied when provision of these dimensions is inadequate. With regard to escape, listed as a performance factor, guests will be satisfied when performance is improved and dissatisfied when performance is low. A positive relationship was also found between overall experience and overall satisfaction. The latter include the likelihood of return and recommending the guesthouse to others. Finally, structural equation modelling confirmed a model representing the 11 experience dimensions (hedonics, peace of mind, involvement, recognition, atmospherics, enjoyment, entertainment, escape, efficiency, excellence, and economic value) and the relationships between overall experience and overall satisfaction pertaining to guesthouses in Ghana.
- Full Text:
- Date Issued: 2016
- Authors: Amoah, Felix
- Date: 2016
- Subjects: Consumer satisfaction -- Ghana , Hospitality industry -- Ghana -- Management , Tourism -- Ghana -- Marketing
- Language: English
- Type: Thesis , Doctoral , DTech
- Identifier: http://hdl.handle.net/10948/6073 , vital:21036
- Description: Guesthouse accommodation plays an important role in Ghana’s hospitality industry and was therefore the focus of this study as little research dealing with guesthouses in Ghana could be found. The number of guesthouses in Ghana continues to grow and they thus represent an important alternative to hotels. However, these establishments seem to perform poorly and face several challenges such as lack of managerial knowledge, insufficiently skilled employees, poor interaction with customers, and criticisms of the provision of low quality service. The main reason for undertaking this research was to provide guesthouse managers in Ghana with information that might assist them in making decisions about the experience they offer. Such knowledge could make this type of accommodation more competitive and eventually help the hospitality sector in Ghana attract tourists and grow. It is imperative that guesthouses focus on the experience they offer, because contemporary tourism and hospitality literature suggest that successful businesses require a shift from functional and financial interests to a more profound focus on total experiences which embody emotional aspects. It is thus argued that, if guesthouse managers in Ghana do not know how their guests perceive their guesthouse experience, they might make costly mistakes and allocate resources to aspects that already provide quality and value in a functional sense, instead of those elements perceived as providing quality and value in the total experience. Two dominating concepts, namely experience quality and experience value, formed the basis of the examination of guests’ experience with the guesthouses in Ghana. In addition, the relationships between the experience and satisfaction were also investigated. Four experience quality dimensions, namely hedonics, peace of mind, involvement, and recognition, and seven value dimensions were examined. The experience value dimensions included atmospherics, enjoyment, entertainment, efficiency, excellence, escape, and economic value. A proportional stratified random sampling procedure was followed to select the guesthouses for the study. Thereafter, a structured questionnaire was distributed to the guesthouse guests selected by means of convenience sampling. Five hundred and forty one useable questionnaires were received. The guesthouse guests formed the primary sampling unit for this study. The results of the empirical study showed a strong positive correlation between all the dimensions of experience quality and experience value, while the factor analysis confirmed that all these dimensions loaded on a single factor. Therefore, experience quality and experience value cannot be separated, and the resulting single multi-dimensional factor was subsequently renamed, overall experience. The results also indicated a positive relationship between hedonics, peace of mind, involvement, recognition, atmospherics, enjoyment, entertainment, efficiency, excellence, escape, economic value, and overall satisfaction. The inferentially established rank-order of the dimensions contributing to satisfaction can guide managers when allocating resources. Overall, atmospherics was ranked first, followed by economic value. Escape was the lowest ranked dimension. In addition, it was found that, except for escape, all the experience dimensions were perceived as basic satisfiers. This implies that guests will be dissatisfied when provision of these dimensions is inadequate. With regard to escape, listed as a performance factor, guests will be satisfied when performance is improved and dissatisfied when performance is low. A positive relationship was also found between overall experience and overall satisfaction. The latter include the likelihood of return and recommending the guesthouse to others. Finally, structural equation modelling confirmed a model representing the 11 experience dimensions (hedonics, peace of mind, involvement, recognition, atmospherics, enjoyment, entertainment, escape, efficiency, excellence, and economic value) and the relationships between overall experience and overall satisfaction pertaining to guesthouses in Ghana.
- Full Text:
- Date Issued: 2016
Congruence between fine-scale genetic breaks and dispersal potential in an estuarine seaweed across multiple transition zones:
- Nicastro, Katy R, Assis, Jorge, Serrão, Ester A, Pearson, Gareth A, Neiva, Joao, Valero, Myriam, Jacinto, Rita, Zardi, Gerardo I
- Authors: Nicastro, Katy R , Assis, Jorge , Serrão, Ester A , Pearson, Gareth A , Neiva, Joao , Valero, Myriam , Jacinto, Rita , Zardi, Gerardo I
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149873 , vital:38908 , https://0-doi.org.wam.seals.ac.za/10.1093/icesjms/fsz179
- Description: Genetic structure in biogeographical transition zones can be shaped by several factors including limited dispersal across barriers, admixture following secondary contact, differential selection, and mating incompatibility. A striking example is found in Northwest France and Northwest Spain, where the estuarine seaweed Fucus ceranoides L. exhibits sharp, regional genetic clustering. This pattern has been related to historical population fragmentation and divergence into distinct glacial refugia, followed by post-glacial expansion and secondary contact. The contemporary persistence of sharp ancient genetic breaks between nearby estuaries has been attributed to prior colonization effects (density barriers) but the effect of oceanographic barriers has not been tested. Here, through a combination of mesoscale sampling (15 consecutive populations) and population genetic data (mtIGS) in NW France, we define regional genetic disjunctions similar to those described in NW Iberia. Most importantly, using high resolution dispersal simulations for Brittany and Iberian populations, we provide evidence for a central role of contemporary hydrodynamics in maintaining genetic breaks across these two major biogeographic transition zones. Our findings further show the importance of a comprehensive understanding of oceanographic regimes in hydrodynamically complex coastal regions to explain the maintenance of sharp genetic breaks along continuously populated coastlines.
- Full Text:
- Date Issued: 2020
- Authors: Nicastro, Katy R , Assis, Jorge , Serrão, Ester A , Pearson, Gareth A , Neiva, Joao , Valero, Myriam , Jacinto, Rita , Zardi, Gerardo I
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149873 , vital:38908 , https://0-doi.org.wam.seals.ac.za/10.1093/icesjms/fsz179
- Description: Genetic structure in biogeographical transition zones can be shaped by several factors including limited dispersal across barriers, admixture following secondary contact, differential selection, and mating incompatibility. A striking example is found in Northwest France and Northwest Spain, where the estuarine seaweed Fucus ceranoides L. exhibits sharp, regional genetic clustering. This pattern has been related to historical population fragmentation and divergence into distinct glacial refugia, followed by post-glacial expansion and secondary contact. The contemporary persistence of sharp ancient genetic breaks between nearby estuaries has been attributed to prior colonization effects (density barriers) but the effect of oceanographic barriers has not been tested. Here, through a combination of mesoscale sampling (15 consecutive populations) and population genetic data (mtIGS) in NW France, we define regional genetic disjunctions similar to those described in NW Iberia. Most importantly, using high resolution dispersal simulations for Brittany and Iberian populations, we provide evidence for a central role of contemporary hydrodynamics in maintaining genetic breaks across these two major biogeographic transition zones. Our findings further show the importance of a comprehensive understanding of oceanographic regimes in hydrodynamically complex coastal regions to explain the maintenance of sharp genetic breaks along continuously populated coastlines.
- Full Text:
- Date Issued: 2020
Governing pregnancy in South Africa: political and health debate, policy and procedures
- Authors: Du Plessis, Ulandi
- Date: 2019
- Subjects: South Africa. Department of Health (1994- ) , Maternal health services -- South Africa , Mothers -- Mortality -- South Africa , Prenatal care -- South Africa , African mothers -- Mortality -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/76552 , vital:30600
- Description: South Africa democratised in 1994. However, due to the discriminatory and segregationist character of the preceding regime, vast swathes of the country’s spaces and people entered the democratic period heavily deprived of essential government services. This was the case with health care in general, including maternal health care. There were also little to no national data available on maternal deaths, especially among the black population. One of the first tasks of the new National Department of Health (NDoH) was to target the high maternal mortality rate. The NDoH made maternal deaths notifiable by law and instituted auditing and information gathering systems in the health sector; health infrastructure was expanded exponentially, and maternal health care was made free. Despite this, the last 24 years have seen the maternal mortality escalate. The latest statistics show that between 1200 and 1300 women die in the South African public health sector each year during pregnancy and the puerperium. This puts the current institutional maternal mortality rate (MMR) at around 154/100 000 live births. The international target for ‘developing’ countries was to reduce the MMR rate by three quarters by 2015, which would have meant a reduction to 38/100 000 live births. The aim of this dissertation is to examine how the democratic South African government (influenced heavily by global health thinking) has laboured to reduce that statistic. I analyse, using Foucauldian discourse analysis, all relevant health and maternal health policies, procedural documents and reports produced by and for the NDoH in the last 24 years. I draw on Foucauldian concepts, specifically those related to Foucault’s work on governmentality. In this dissertation I introduce a new perspective towards the maternal health practices implemented in South Africa, practices that have generally remained unquestioned, been perceived as self-evident, and thus often escaping critical analysis. Through an analysis of the intended operation of the public antenatal clinic (within the larger institutional system) I show how ‘development’ has come to operate as a truth regime in South Africa – facilitating the introduction of liberal governmentality (including some advanced liberal practices) into public health service provision.
- Full Text:
- Date Issued: 2019
- Authors: Du Plessis, Ulandi
- Date: 2019
- Subjects: South Africa. Department of Health (1994- ) , Maternal health services -- South Africa , Mothers -- Mortality -- South Africa , Prenatal care -- South Africa , African mothers -- Mortality -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/76552 , vital:30600
- Description: South Africa democratised in 1994. However, due to the discriminatory and segregationist character of the preceding regime, vast swathes of the country’s spaces and people entered the democratic period heavily deprived of essential government services. This was the case with health care in general, including maternal health care. There were also little to no national data available on maternal deaths, especially among the black population. One of the first tasks of the new National Department of Health (NDoH) was to target the high maternal mortality rate. The NDoH made maternal deaths notifiable by law and instituted auditing and information gathering systems in the health sector; health infrastructure was expanded exponentially, and maternal health care was made free. Despite this, the last 24 years have seen the maternal mortality escalate. The latest statistics show that between 1200 and 1300 women die in the South African public health sector each year during pregnancy and the puerperium. This puts the current institutional maternal mortality rate (MMR) at around 154/100 000 live births. The international target for ‘developing’ countries was to reduce the MMR rate by three quarters by 2015, which would have meant a reduction to 38/100 000 live births. The aim of this dissertation is to examine how the democratic South African government (influenced heavily by global health thinking) has laboured to reduce that statistic. I analyse, using Foucauldian discourse analysis, all relevant health and maternal health policies, procedural documents and reports produced by and for the NDoH in the last 24 years. I draw on Foucauldian concepts, specifically those related to Foucault’s work on governmentality. In this dissertation I introduce a new perspective towards the maternal health practices implemented in South Africa, practices that have generally remained unquestioned, been perceived as self-evident, and thus often escaping critical analysis. Through an analysis of the intended operation of the public antenatal clinic (within the larger institutional system) I show how ‘development’ has come to operate as a truth regime in South Africa – facilitating the introduction of liberal governmentality (including some advanced liberal practices) into public health service provision.
- Full Text:
- Date Issued: 2019
Where are the men? : an investigation into female-headed households in Rini, with reference to household structures, the dynamics of gender and strategies against poverty
- Authors: Brown, Brenda
- Date: 1996
- Subjects: Women heads of households -- South Africa , Poor women -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2097 , http://hdl.handle.net/10962/d1002660 , Women heads of households -- South Africa , Poor women -- South Africa
- Description: An in-depth study is conducted into ten female-headed households in the township of Rini, an underprivileged section of Grahamstown in the Eastem Cape region of South Africa. The study provides information on the way in which such households function in conditions of poverty and underemployment. The meaning of the term 'household' is clearly defined. A household consists of a group of people, who may or may not be kin-related, but who usually live under the same roof, eat together and share resources. Household members may be absent for varying periods of time, but are still considered to have rights in the household to which they belong. The female-headed household usually contains a core of adult women who are often uterine kin. Men are frequently members of these households and are usually related to the women who form the core. Their status and roles in such households are defined and intra-household relations between household members are discussed. In this study, female headship is observed to occur in conditions of poverty when an elderly woman is widowed, receives a regular income in the form of and old age pension, and when her status as the senior member of the household is acknowledged. The presence of men in female-headed households has not been widely emphasised in other studies, either of the female-headed household itself, or in research done in this area of South Africa. An attempt is therefore made to illustrate the way in which men function in these households and the varying roles they play. An attempt is also made to describe other structures and practices which support the female-headed household in a rapidly changing urban environment. These include church membership, burial society membership, the informal economy, wider kinship networks and, in the case of the men, the rite of circumcision.
- Full Text:
- Date Issued: 1996
- Authors: Brown, Brenda
- Date: 1996
- Subjects: Women heads of households -- South Africa , Poor women -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2097 , http://hdl.handle.net/10962/d1002660 , Women heads of households -- South Africa , Poor women -- South Africa
- Description: An in-depth study is conducted into ten female-headed households in the township of Rini, an underprivileged section of Grahamstown in the Eastem Cape region of South Africa. The study provides information on the way in which such households function in conditions of poverty and underemployment. The meaning of the term 'household' is clearly defined. A household consists of a group of people, who may or may not be kin-related, but who usually live under the same roof, eat together and share resources. Household members may be absent for varying periods of time, but are still considered to have rights in the household to which they belong. The female-headed household usually contains a core of adult women who are often uterine kin. Men are frequently members of these households and are usually related to the women who form the core. Their status and roles in such households are defined and intra-household relations between household members are discussed. In this study, female headship is observed to occur in conditions of poverty when an elderly woman is widowed, receives a regular income in the form of and old age pension, and when her status as the senior member of the household is acknowledged. The presence of men in female-headed households has not been widely emphasised in other studies, either of the female-headed household itself, or in research done in this area of South Africa. An attempt is therefore made to illustrate the way in which men function in these households and the varying roles they play. An attempt is also made to describe other structures and practices which support the female-headed household in a rapidly changing urban environment. These include church membership, burial society membership, the informal economy, wider kinship networks and, in the case of the men, the rite of circumcision.
- Full Text:
- Date Issued: 1996