A comparison of implementation platforms for the visualisation of animal family trees
- Authors: Kanotangudza, Priviledge
- Date: 2024-04
- Subjects: Business intelligence -- Computer programs , Human-computer interaction , Computer science
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64105 , vital:73653
- Description: Genealogy is the study of family history. Family trees are used to show ancestry and visualise family history. Animal family trees are different from human family trees as animals have more offspring to represent in a family tree visualisation. Auctioneering organisations, such as Boere Korporasie Beperk (BKB), provide livestock auction catalogues containing pictures of the animal on sale, the animal’s family tree and its breeding and selection data. Modern-day farming has become data-driven and livestock farmers use various online devices and platforms to obtain information, such as real-time milk production, animal health monitoring and to manage farming operations. This study investigated and compared two Business Intelligence (BI) platforms namely Microsoft Power BI and Tableau (Salesforce) and the Python programming language used in the implementation of cattle family tree charts. Animal family tree visualisation requirements were identified from analysing data collected from 23 agriculture users and auction attendees who responded to an online questionnaire. The results of an online survey showed that agriculture users preferred an animal family tree that resembled a human one, which is not currently used in livestock auction catalogues. A conference paper was published based on the survey results. The Design Science Research Methodology (DSRM) was used to aid in creating animal family tree charts using Power BI, Tableau and Python. The author compared the visualisation tools against selected criteria, such as learnability, portability interoperability and security. Usability evaluations using eye tracking were conducted with agriculture users in a usability lab to compare the artefacts developed using Power BI and Python. Tableau was discarded during the implementation process as it did not produce the required family tree visualisation The Technology Acceptance Model (TAM) theory, which seeks to predict the acceptance and use of technology based on users' perception of its usefulness and ease of use, was used to guide the research study in evaluating the artefacts. According to TAM, the adoption of the proposed technology to solve the problem of a static animal family tree in livestock auction catalogues was dependent on the agriculture user’s beliefs. This was based upon that the technology would help them make better buying decisions at livestock auctions effortlessly. The other theory used in this study was the Task Technology Fit (TTF). This theory was used mainly to create the task list to be used in the usability test. The results showed that the author of this work and the agriculture users preferred the artefact produced by Power BI. The learnability and development time was shorter and the User Interface (UI) created was more intuitive. The findings of this study indicated that the present auction catalogue could be supplemented using interactive online animal family tree visualisations created using Power BI. This study recommended that livestock auctioneering organisations should, in addition to providing paper catalogues, provide farmers with an online platform to view the family trees of cattle on auction to enhance purchasing decisions. , Thesis (MCom) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2024
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- Date Issued: 2024-04
A methodology for modernising legacy web applications: subtitle if needed. If no subtitle follow instructions in manual
- Authors: Malgraff, Maxine
- Date: 2024-04
- Subjects: Management information systems , Information technology , Application software -- Development
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64148 , vital:73657
- Description: One problem faced in the Information Systems domain is that of poorly maintained, poorly documented, and/or unmanageable systems, known as Legacy Information Systems (LISs). As a result of the everchanging web development landscape, web applications have also become susceptible to the challenges faced in keeping up with technological advances, and older applications are starting to display the characteristics of becoming Legacy Web Applications (LWAs). As retaining business process support and meeting business requirements is often necessary, one method of recovering vital LWAs is to modernise them. System modernisation aims to recover business knowledge and provide an enhanced system that overcomes the problems plagued by LISs. When planning to modernise an LWA, guidance and support are essential to ensure that the modernisation exercise is performed efficiently and effectively. Modernisation methodologies can provide this required guidance and support as they provide models, tools and techniques that serve as guiding principles for the modernisation process. Although many modernisation methodologies exist, very few offer a comprehensive approach to modernisation that provides guidelines for each modernisation phase, tools to assist in the modernisation and techniques that can be used throughout. Existing methodologies also do not cater for cases that include both the LWA and migration to modernised web-specific environments. This research study aimed to investigate modernisation methodologies and identify which methodologies, or parts thereof, could be adapted for modernising LWAs. Existing methodologies were analysed and compared using the definition of a methodology, as well as other factors that improve the modernisation process. Modernisation case studies were reviewed to identify lessons learned from these studies so that these could be considered when planning an LWA modernisation. The ARTIST methodology was the most comprehensive modernisation methodology identified from those researched and was selected as the most appropriate methodology for modernising an LWA. ARTIST was modified to the mARTIST methodology to cater for web-based environments.mARTIST was used to modernise an existing LWA, called OldMax, at an automotive manufacturer, anonymously referred to as AutoCo, to determine its ability to support the modernisation of LWAs. Additional tools and evaluation methods were also investigated and used in place of those recommended by ARTIST, where deemed appropriate for the modernisation of OldMax. Limitations set by AutoCo on the hosting and technical environments for the modernised application also required ARTIST to be adapted to better suit the use case. The steps taken during this modernisation were documented and reported on to highlight the effectiveness of mARTIST and the tools used. The result of this modernisation was that the modernised web application, ModMax, was evaluated to determine the success of the modernisation. The modernisation of OldMax to ModMax, using the mARTIST methodology, was found to be successful based on the criteria set by the ARTIST methodology. Based on this, mARTIST can successfully be used for the modernisation of LWAs. To support future modernisations, an evaluation method for determining technical feasibility was developed for LWA, and alternate tools that could be used throughout modernisation exercises were recommended. , Thesis (MSc) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2024
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- Date Issued: 2024-04
A model for measuring and predicting stress for software developers using vital signs and activities
- Authors: Hibbers, Ilze
- Date: 2024-04
- Subjects: Machine learning , Neural networks (Computer science) , Computer software developers
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63799 , vital:73614
- Description: Occupational stress is a well-recognised issue that affects individuals in various professions and industries. Reducing occupational stress has multiple benefits, such as improving employee's health and performance. This study proposes a model to measure and predict occupational stress using data collected in a real IT office environment. Different data sources, such as questionnaires, application software (RescueTime) and Fitbit smartwatches were used for collecting heart rate (HR), facial emotions, computer interactions, and application usage. The results of the Demand Control Support and Effort and Reward questionnaires indicated that the participants experienced high social support and an average level of workload. Participants also reported their daily perceived stress and workload level using a 5- point score. The perceived stress of the participants was overall neutral. There was no correlation found between HR, interactions, fear, and meetings. K-means and Bernoulli algorithms were applied to the dataset and two well-separated clusters were formed. The centroids indicated that higher heart rates were grouped either with meetings or had a higher difference in the center point values for interactions. Silhouette scores and 5-fold-validation were used to measure the accuracy of the clusters. However, these clusters were unable to predict the daily reported stress levels. Calculations were done on the computer usage data to measure interaction speeds and time spent working, in meetings, or away from the computer. These calculations were used as input into a decision tree with the reported daily stress levels. The results of the tree helped to identify which patterns lead to stressful days. The results indicated that days with high time pressure led to more reported stress. A new, more general tree was developed, which was able to predict 82 per cent of the daily stress reported. The main discovery of the research was that stress does not have a straightforward connection with computer interactions, facial emotions, or meetings. High interactions sometimes lead to stress and other times do not. So, predicting stress involves finding patterns and how data from different data sources interact with each other. Future work will revolve around validating the model in more office environments around South Africa. , Thesis (MSc) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2024
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- Date Issued: 2024-04
A model for speech-driven lesson summary generation in a noisy educational environment
- Authors: Blunt, Phillip John
- Date: 2024-04
- Subjects: Automatic speech recognition , Speech processing systems , Educational technology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64500 , vital:73741
- Description: The application of Automatic Speech Recognition (ASR) technology for generating lesson transcripts and closed captions in the classroom has shown to improve the learning experience of people in disadvantaged student groups. This dissertation proposes a concept model for applying ASR technology in the educational environment for lesson transcription or closed captioning. The model aims further to bolster students’ secondary contact with the lesson content using keyword identification and subsequent association to generate a summary of the educator’s key points with reference to known course content material. To reinforce this concept, three core theoretical areas are discussed in this work, namely the existing applications of ASR technology in the classroom, the prominent machine-learning solutions that are capable of performing ASR, either for keyword spotting or for continuous speech recognition, and finally, the speech enhancement techniques used to mitigate the negative effects of environmental noise in the educational space. After a groundwork investigation into these three core theoretical areas, an initial model was created for incorporating an ASR system into the educational environment using the speech of the educator to drive the process of generating the lesson summary. After analysis for prototype development, the feasibility of developing a keyword-spotting system using South African speech data to train a machine-learning model revealed a number of challenges. Hence, it was decided that it would be more appropriate to implement a cloud-based ASR solution to establish proof of concept in a prototype system. In addition, the advent of a cloud-based ASR solution meant that a more reliable lesson transcript could be generated and, as a result, the direction of this work could move towards exploiting the utility provided by lesson transcription to generate a meaningful lesson summary. An initial prototype implementation was then developed based on the initial model using a cloud-based ASR approach. The final model presented in this work makes use of keyword identification in the transcription process, in collaboration with a course content database to identify known, educator-defined keyword terms during a lesson that are tied to relevant course content items for the specified lesson. As the model or prototype was improved and adapted, its counterpart was modified appropriately, ensuring that each reflected both the theoretical and practical aspects of the other. After a series of improvement cycles, a final version of the model was ascertained, supported by a performance evaluation of an acceptable prototype system. Ultimately, the prototype proved capable of generating a lesson summary, presented to students to bolster secondary contact with lesson content. This lesson summary provides students with a lesson transcript, but also helps them to monitor educator-defined keyword terms, their prevalence as communicated in the lesson by the educator, and their associations with educator-defined sections of course content. The prototype was developed with a modular approach so that its speech recognition component was interchangeable between CMU’s Sphinx and Google Cloud’ Speech-to-Text speech recognition systems, both accessed via a cloud-based programming library. In addition to the ASR module, noise injection, cancellation and reduction were also introduced to the prototype as a speech enhancement module to demonstrate the effects of noise on the prototype. The prototype was tested using different configurations of speech recognition- and speech enhancement techniques to demonstrate the change in accuracy of lesson summary generation. Proof of concept was established using the Google Cloud Continuous Speech Recognition System, which prevailed over CMU’s Sphinx and enabled the prototype to achieve 100,00% accuracy in keyword identification and subsequent association on noise-free speech, contrasted with a 96,93% accuracy in keyword identification and subsequent association on noise-polluted speech when applying noise cancellation. , Thesis (MIT) -- Faculty of Engineering, the Built Environment, and Technology, School of Information Technology, 2024
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- Date Issued: 2024-04
A process for integrated fitness and menstrual cycle data visualisations
- Authors: Taljaard, Isabelle
- Date: 2024-04
- Subjects: Human-computer interaction , Personal information management , Medical informatics -- Standards
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64379 , vital:73689
- Description: The increase in female participation in sport has led to an increase in research reporting on the relationship between fitness and menstrual cycle (F&M) data. Fitness variables such as VO2 max and heart rate are influenced by menstrual hormones and change with the different phases of a cycle. People frequently track both their F&M data, to understand their long-term activity and their body’s changes during the different cycle phases. Both these data sets are tracked and visualised separately to help people understand their data, however little work has been done to visualise the relationship between the two data sets. A process that guides the creation of an integrated F&M visualisation does not exist. This research aimed to develop and adopt a process that could be used to successfully guide the creation of an integrated F&M visualisation. The study followed the Design Science Research Methodology (DSRM) to create a primary and secondary artefact – the process and instantiation thereof. The DSRM was applied in iterative cycles where the process was developed, instantiations created and evaluated by participants. To develop the process, existing data processing and visualisation processes were reviewed from literature, to assess their successes and shortcomings. The review of existing processes revealed what steps, and factors related to those steps, would need to be considered. The process review highlighted the importance of five process steps: planning, collection, access, integration, and visualisation. Once the conceptual process was designed, it was adapted for the goal of creating an integrated F&M data visualisation. Prior to implementation, the process was first tested in a pilot study to ensure its validity before involving participants in data collection. After the process pilot study, the final implementation of the process took place and participants were recruited. In the first step of the process, the different fitness data types that are influenced by the menstrual cycle, and vice versa, were identified through a literature review. In the second step, devices to be used for data collection were evaluated and tested through exploratory testing and review of user manuals available online. The third and fourth steps, access, and integration were informed by further exploratory testing and review of relevant literature. The fifth step, data visualisation, was guided by relevant studies, Hick’s law, and the Schema Theory. Two Iterations of DSR were conducted in two phases. Phase 1 (P1) was the instantiation of the planning, collection, access, and processing steps. Participants wore smartwatches while going about their daily lives and working out and tracked their menstrual cycle to collect data. P1data was used to create several instantiations of the process. The second phase (P2) was the instantiation the visualisation step. The final visualisations, resulting from the instantiations, were evaluated by participants in P2. The review notes were used to improve both the process and the final visualisations. Both P1 and P2 were repeated (iterated) twice. The recommended process can be used by anyone who wants to create an integrated F&M visualisation and was designed to be modular so that users could choose to follow the whole process or only specific steps. The findings of this research can provide guidance to users, developers and smartwatch manufacturers of what people’s preferences are for these integrated visualisations. It also provides guidance for those who wish to create their own visualisations without needing prior programming experience or knowledge, since easy to use, online visualisation tools are recommended. The process instantiations will assist people, especially women, to better understand their menstrual cycle and how it affects their physical well-being. , Thesis (MCom) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2024
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- Date Issued: 2024-04
A qualitative review on the manner in which psychologists address language barriers in psychological testing with isiXhosa speaking clients
- Authors: Fouche, Nicoleen Leonie
- Date: 2024-04
- Subjects: Language and languages -- Psychological aspects , Psychological tests -- South Africa -- Eastern Cape , Counseling psychology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63835 , vital:73618
- Description: A racially segregated culture historically influenced the growth of psychological testing and evaluation in South Africa. Thus, South Africa's multicultural and multilingual community poses difficulties for psychologists in their daily work. Most of the psychological tests used by psychologists are predominantly normed in either or only English/Afrikaans. Given the economic and professional resources required to develop new standardised tests for the broader South African population, the current status quo is set to continue for the foreseeable future. Consequently, language barriers pose a challenge when psychometric standardised tests are administered in a language that is different from that of the client, and as a result, psychologists must develop ways to enhance the fairness of these measures for their client base. The avenue of research that was explored is how psychologists overcome the language boundary when assessing clients who speak an indigenous first language, particularly isiXhosa. As such, this study explored this question through qualitative methods. Through purposive sampling, nine psychologists were invited to share their practical expertise on this topic, using semi-structured online interviews. The findings of this study suggested several core themes providing useful methods for other psychologists facing the same challenge, including the challenges with administering psychological tests with isiXhosa clients, the availability of standardised tests in the South African context, and the importance of determining the client’s language proficiency. Five themes with several sub-themes emerged from the study. The study contributes to the currently limited existing body of knowledge, and subsequently to the research area that this study explores - thus further providing guidelines that practitioners can employ when working with clients who are isiXhosa speaking. , Thesis (MA) -- Faculty of Health Science, School of Behavioural & Lifestyle Sciences, 2024
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- Date Issued: 2024-04
A review of the quality of the covid-19 terminology that has been translated into isiXhosa
- Authors: Kamtein, Khanyisa
- Date: 2024-04
- Subjects: African languages -- Translating , Communication -- Language , Communication in medicine
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63080 , vital:73185
- Description: The outbreak of the Covid-19 pandemic affected the whole world. Consequently, countries were forced to lock down and citizens had to be quarantined to control the spread of the virus. Accordingly, the World Health Organization (WHO) came up with safety measures to try and mitigate the spread of the virus. These measures included Covid-19 health communication, and this communication was transmitted mostly through the media. However, this crucial health communication was mostly conveyed in English. The cascading of the Covid-19 health communication in English proved to be problematic worldwide especially for linguistically diverse countries like South Africa. As a result, the South African government had to put measures in place to ensure that the health communication regarding Covid-19 could reach every citizen in the country by commissioning translation services to urgently translate terms relating to Covid-19 into all the South African indigenous languages including isiXhosa. Hence the South African government and City of Tshwane decided to enlist the services of the South African Centre for Digital Language Resources (SaDiLaR) and the Pan South African Language Board (PanSALB) to translate the Covid-19 terminology into all the indigenous languages spoken in the country. This study therefore aims to examine the quality and the accuracy of the translated Covid-19 terms into isiXhosa especially since the translation of these terms had to be done urgently. The study will follow a qualitative method approach and use the skopos theory as the lens of the study. Skopos refers to purpose, intention, and aim. The theory is known as a purpose for action and the reader in this theory is important in determining the purpose of the translation at hand. In evaluating the terminology that has been translated the theory will be applied to determine whether the purpose and the aim of the terminology was adequately carried out to the intended audience. The English terms and isiXhosa terms collected in this research which will be analysed are sourced from the material that was developed and compiled by SaDiLaR and PanSALB and subsequently cascaded to the public during the Covid-19 pandemic. The study will analyse only the (75) translated isiXhosa terms. , Thesis (MA) -- Faculty of Humanities, School of Language, Media and Communication, 2024
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- Date Issued: 2024-04
An assessment of community participation in disaster management: A Case Study of Nelson Mandela Bay Municipality
- Authors: Stemele, Lwandiso Phololo
- Date: 2024-04
- Subjects: Disaster relief -- South Africa -- Port Elizabeth , Crisis management -- South Africa -- Port Elizabeth , Political participation -- South Africa -- Eastern Cape -- Nelson Mandela Bay Municipality
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63540 , vital:73489
- Description: This study sought to assess the level of community participation in disaster management by the communities that are most affected by floods and fires in informal settlements. The study aimed to assess the level of awareness of disaster risks at a community level and thereby provide recommendations to increase the level of participation, involvement and awareness in disaster management by the communities. This research adopted both qualitative and quantitative research approaches to form a mixed-method research approach. Data was collected using both approaches and converged to form the results and analysis of the empirical survey. From these results and analysis, recommendations are presented, which also draw insight from the literature review, to assist the Nelson Mandela Bay Municipality to better involve communities in disaster management. , Thesis (MA) -- Faculty of Humanities, School of Governmental and Social Sciences, 2024
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- Date Issued: 2024-04
An assessment of the presidential youth employment programme on job creation in the department of Education, Eastern Cape
- Authors: Mnqwazi, Zweledinga
- Date: 2024-04
- Subjects: Job creation -- South Africa -- Eastern Cape , Youth development -- South Africa -- Eastern Cape , Youth -- Services for
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63357 , vital:73260
- Description: The presidential youth employment stimulus programme is a prominent imitative by the South African government aimed at addressing poverty and youth unemployment in the country. the programme has created many job opportunities for the youth in various government departments. in this study, the primary focus was on examining the impact of the programme on job creation within the Eastern Cape Department of Education, a province characterized by unique socio-economic challenges. The focused approach aimed to provide contextually relevant findings that may possibly contribute to the broader understanding of youth employment interventions on job creation. A qualitative study based on secondary data collection techniques was used to find answers to the research questions. Government reports, textbooks, and reports from the Eastern Cape Department of Education were the sources of data collection . In analyzing the gathered data, thematic analysis was employed following the guidelines by Braun and Clarke (2006). The study findings provide insights into the strengths of the presidential youth employment initiative, which includes employment opportunities, skills development and training. , Thesis (MPA) -- Faculty of Humanities, School of Governmental and Social Sciences, 2024
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- Date Issued: 2024-04
An assessment of the youth employment creation strategy in Buffalo City Metropolitan Municipality: a case of Isiqalo Youth Fund
- Authors: Tantsi, Yanga Ntombizodidi
- Date: 2024-04
- Subjects: Youth -- Employment -- South Africa -- Eastern Cape -- Buffalo City Metropolitan Municipality , Youth -- Employment -- Government policy , Youth development -- South Africa Eastern Cape -- Finance
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63551 , vital:73492
- Description: Youth unemployment is a persistent and pressing challenge faced by communities and governments worldwide. In Buffalo City Metropolitan Municipality, a region characterised by its diverse socioeconomic landscape and unique set of opportunities and constraints, the issue of youth unemployment is of particular concern. The Isiqalo Youth Fund was established as a strategic initiative to address this challenge and promote economic empowerment and employability among the youth. This fund was designed to provide financial support and resources to young individuals in the municipality, offering them the opportunity to gain the skills, training, and experience required to enter the workforce and make meaningful contributions to the local economy. The study aimed to assess the implementation of the Isiqalo Youth Fund, which aims to facilitate youth employment in Buffalo City Metropolitan Municipality. The study utilised the qualitative research methodology, and the sample was selected using a purposive sampling technique. The sample for this study comprised ten youth beneficiaries of the Isiqalo Youth Fund, five officials from the Office of the Premier, and five officials from the Department of Economic Development, Environmental Affairs and Tourism (DEDEAT) responsible for the administration and oversight of the fund. Semi-structured interviews were conducted to capture the experiences and perceptions of the youth beneficiaries and the insights of the officials involved in the implementation of the Isiqalo Youth Fund. The study’s findings from the beneficiaries’ perspective indicate that accessing the Isiqalo Youth Fund is associated with several challenges, such as high levels of bureaucracy, poor fund management, a lack of information, lack of proper monitoring and evaluation mechanisms, and complex application procedures. The findings from the administrators’ perspectives indicated that a lack of ethics, fair dealing, and accountability adversely influenced the effective administration of the Isiqalo Youth Fund. The study recommends that local authorities and stakeholders collaborate to simplify the application process, improve fund management, increase awareness, offer support and mentorship, and enhance project monitoring and evaluation. , Thesis (MA) -- Faculty of Humanities, School of Public Management and Leadership, 2024
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- Date Issued: 2024-04
An evaluation of the monitoring and evaluation process of the scholar transport programme: a case of Amthole West Education District
- Authors: Tengile, Sindisiwe
- Date: 2024-04
- Subjects: Monitoring , Evaluation , Transportation -- South Africa -- Eastern Cape
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63562 , vital:73503
- Description: Access to education is a constitutional right, calling for the state to institute reasonable measures to ensure every learner has access to education. The scholar transport programme was introduced to ensure access to education for learners who live far from school, particularly those living in rural areas. The study aimed to evaluate the processes that the scholar transport programme utilizes in the Amatole West Education District. Change theory served as the theoretical framework underpinning this qualitative study. Secondary data was collected and analyzed using thematic analysis. The study revealed that the Amatole West Education District employs several strategies, including stakeholder participation, route scrutiny, and safety checks. The research identified a lack of resources and capacity constraints as challenges to the Amatole West Education District encounter. The study recommends that the district enhance the competence of employees and other stakeholders with the necessary skills and knowledge to enable them to perform monitoring and evaluation(M&E) completely. , Thesis (MPA) -- Faculty of Humanities, School of Governmental and Social Sciences, 2024
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- Date Issued: 2024-04
An in vitro assessment of pharmacodynamic interactions between selected herbal extracts and anticancer chemotherapeutic agents
- Authors: Hwehwe, Nyashadzashe , Swanepoel, Bresler
- Date: 2024-04
- Subjects: Chemotherapy , Herbs -- Therapeutic use , Antineoplastic agents
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63506 , vital:73383
- Description: Cancer is a disease caused by uncontrolled growth and spreading of abnormal cells to distant body parts. Approximately 19.3 million and 10 million new cancer cases and cancer deaths, respectively were recorded in 2020. Despite advancements in prevention and therapeutic strategies, cancer remains a global health problem. Cancer patients are increasingly seeking complementary and alternative medicines, of which herbal medicines are the most common form of CAM used by patients. Numerous in vitro and in vivo studies of herbal medicines in cancer have shown that they have antioxidant and anticancer (antitumor and anti-proliferative) properties. While concurrent use with conventional cancer treatments may improve treatment efficacy, alleviate chemotherapy-related side effects, boost the immune system, or impede drug resistance, it can also prompt drug-herbal interactions, and this may affect the pharmacodynamics and pharmacokinetics of the chemotherapeutic drug. This study aimed to determine relevant pharmacodynamic interactions with chemotherapeutic drugs and investigate such interactions' mechanisms. The objectives of the study were to screen the cytotoxicity effects of drug compounds, herbal extracts, and drug-herb combinations, to determine the ability of treatments to induce apoptosis, and to determine the most beneficial treatment. The cytotoxic effects of cisplatin in HeLa cells, tamoxifen in MCF7 cells, 5-fluorouracil in Caco-2 cells, and grapeseed, green tea, fermented rooibos, and green rooibos in all the listed cell lines were evaluated individually and in combination using the bis-Benzamide H 33342 trihydrochloride/propidium iodide (Hoechst 33342/PI) dual staining method. CompuSyn 1.0 Software was used to quantify synergism and antagonism. The mechanism of apoptosis induction of the different synergetic combinations, drug compounds, and herbal extracts was illustrated by quantitative fluorescence image analysis, specifically cell cycle analysis, phosphatidylserine translocation, mitochondrial membrane potential analysis, caspase 3 activation, and reactive oxygen species production using the relevant contrast dyes. Grapeseed displayed cytotoxicity towards MCF7 and HeLa cells (IC50 57.98 and 83.28 μg/mL, respectively). Green tea was only cytotoxic against HeLa cells at an IC50 of 91,92 μg/mL. None of the extracts displayed cytotoxicity against Caco-2 cells (IC50 values > 200μg/mL). If the herbal extracts had inconclusive IC50 values in the three cell lines subsequent experiments were conducted using 100 μg/mL. The results showed that most of the combinations were antagonistic but, some combinations had synergistic or enhancement effects(1:3 for cisplatin with grape seed or green tea and tamoxifen with grapeseed or green tea, and 3:1 for cisplatin with green tea as well as for tamoxifen with fermented rooibos or green rooibos, and all the 1:1 combinations of 5- fluorouracil with all herbal extracts) with a combination index (CI) < 1. Grape seed and green tea were found to induce apoptosis in the three cell lines. Assays that were conducted to detect apoptosis induction showed positive staining for phosphatidylserine (PS), activated caspase 3, and reactive oxygen species (ROS), mitochondrial membrane depolarization. Analysis of the cell cycle showed two things; 1) that grape seed and green tea were apoptotic in HeLa and MCF7 cells only, and 2) the extracts of green tea and green rooibos, and the combinations of grape seed with all drug compounds arrested the cell in more than one phase of the cell cycle. The combinations of grapeseed and green tea potentially induced apoptosis in various manners but those with both rooibos extracts were unclear in all the cell lines. The results for combinations with grapeseed and green tea are promising and provide a basis for further research as combinations of chemotherapeutic drugs and herbal extracts may be effective therapeutic strategies. , Thesis (MPharm) -- Faculty of Health Sciences, School of Clinical Care & Medicinal Sciences, 2024
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- Date Issued: 2024-04
An in vitro evaluation of the anti-breast cancer activity of Nigella sativa extracts and its bioactive compound in combination with curcumin
- Authors: Botha, Susanna Gertruida
- Date: 2024-04
- Subjects: Herbs -- Therapeutic use , Radiation-protective agents , Breast -- Cancer -- Treatment
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63639 , vital:73571
- Description: Breast cancer constitutes 23% of all cancers in South African females. Curcumin and Nigella sativa have anti-cancer, anti-metastatic and antioxidant-properties and may be effective against breast cancer. This study focused on the effect of N. sativa extracts or thymoquinone and curcumin, individually and in combination, on breast cancer cells. An MTT assay showed that curcumin reduced cell viability by 50% (IC50) at 18 ± 2.63 μg/mL and thymoquinone (TQ) at 5 ± 0.95 μg/mL against the MDA-MB-231 cells. The IC50 values for curcumin and TQ were 35 ± 6.98 μg/mL and 4 ± 0.96 μg/mL against the MCF-7 cells, respectively. The IC50 value for the NSBE was determined to be 350 ± 55 μg/mL. The IC50 value of NSAE did not fall within the selected concentration range. Synergism was noted for combinations of NSBE with curcumin, and combinations of TQ with curcumin, against both MCF-7 and MDA-MB-231 cells. Two synergistic combinations per treatment per cell line, as determined by the combination index analysis, were chosen for further investigation. The combinations and individual treatments tested against the MCF-10A cells, were not significant, except for NSBE80:CURC20 combination. Curcumin had the most significant anti-oxidant activity; however, no link was noted between the anti-oxidant activity and the cytotoxicity of the combinations. The combination treatments induced apoptosis more effectively than the individual treatments. Caspase-3 dependent apoptosis was noted for NSBE10:CURC90 and TQ80:CURC20 combinations against the MDA-MB-231 cells, and the TQ60:CURC40 combination against the MCF-7 cells. The individual and combined treatments effectively reduced MDA-MB-231 cell adhesion to fibronectin, but not all reduced the cell adhesion to laminin. Based on these results, the combinations of curcumin with TQ or NSBE, have promising anticancer benefits against breast cancer. , Thesis (MSc) -- Faculty of Science, School of Biomolecular & Chemical Sciences, 2024
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- Date Issued: 2024-04
An Investigation into the challenges of translating mathematical terminologies into Xitsonga
- Authors: Sambo, Tintswalo Teressa
- Date: 2024-04
- Subjects: Mathematical linguistics , Mathematics , Translating and interpreting
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63495 , vital:73382
- Description: Mathematics in South Africa is one of the subjects that is considered ‘difficult’ by many learners. The proof of this statement is reflected by the low mathematical pass rate in many South African schools. One of the challenges that has been highlighted by learners and teachers is that the language of mathematics is challenging. This implies that learners find it difficult to understand some of the mathematical terminologies and content that is being taught. The main reason for the challenge of grasping mathematical terminologies that has been cited by learners and educators is the language of learning and teaching (LOLT). Mathematics is taught in English in most South African schools even though many learners speak one of the indigenous South African official languages (if one excludes English and Afrikaans) at home and get to use and be exposed to English as the medium of learning and teaching only at school. While mathematics remains a challenge in South Africa, research shows that when home languages are used in a mathematics classroom, it enhances the learners understanding. However, it is not always simple to transfer mathematics from English to an African language. There are complexities associated with translation that include the lack of vocabulary in the target language which in this case is Xitsonga. The lack of terminologies in Xitsonga is one of the challenges that occur during the process of translation. This purpose of this research is to examine the challenges of translating mathematical terminologies from English into Xitsonga and to find the strategies that can be used to assist learners to improve their understanding of mathematics. As such, a qualitative research method will be used to select the mathematical terminologies extracted froma mathematics bilingual dictionary with the aim of examining the quality of the translation and identifying the challenges that have been experience by translators. , Thesis (MA) -- Faculty of Humanities, School of Language, Media and Communication, 2024
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- Date Issued: 2024-04
Assessing rural senior primary school natural science teachers’ TPACK: a case study
- Authors: Silvanus, Secilia Tulikefo
- Date: 2024-04
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/423902 , vital:72103
- Description: In today's world, technology has changed how people live and behave. The influence of technology contemplates a similar change in the education processes of teaching and learning. Many governments worldwide invest hugely in providing technological tools and facilities and training teachers to improve teaching and learning. The availability and access to technologies in schools seem to offer teachers opportunities to develop technological knowledge and integrate technology into teaching. Literature indicates that teachers must possess technological pedagogical content knowledge (TPACK) to integrate technology into teaching and learning processes effectively. However, other scholars have also suggested that teachers' TPACK develops and is shaped by many contexts. This study, therefore, sought to assess the rural senior primary Natural science teachers' TPACK. This qualitative case study was conducted with senior primary Natural science teachers in the educational circuit of Endola. An interpretive paradigm underpinned the study. The study employed semi-structured questionnaires, semi-structured interviews, focus group interviews, and observation to collect the data. The study used the TPACK as a theoretical and analytical framework. The study results showed that participants had a firmer grasp of subject content (CK) and traditional teaching methods (Pedagogical Knowledge - PK and Pedagogical Content Knowledge - PCK) compared to technological knowledge (TK) and technology-based pedagogies (Technological Pedagogical Knowledge - TPK, Technological Content Knowledge - TCK, and Technological Pedagogical Content Knowledge (TPCK). Findings support that the participants draw upon sources of Technological Pedagogical Content Knowledge (TPACK) closely aligned with Content Knowledge (CK), Technological Content Knowledge (TCK), and Technological Pedagogical Knowledge (TPK) to integrate technology. The study included inadequate professional development, teachers' attitudes, insufficient hardware and internet connectivity, limited technological knowledge, time constraints, and restricted access to technology tools and resources as obstacles for teachers attempting to incorporate technology into their classrooms effectively. Furthermore, the data highlights ICT training and teachers' interest as enablers that motivated participants to integrate technology into their teaching practices. Therefore, the study recommends professional development programs focusing on providing science teachers with practical skills to utilise different technologies and address common technical issues. , Thesis (MEd) -- Faculty of Education, Secondary and Post-School Education, 2024
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- Date Issued: 2024-04
Assessing the management of water services in Fairview, Harry Gwala district municipality
- Authors: Mazibuko, Nosipho Faith
- Date: 2024-04
- Subjects: Water-supply -- Research -- Management , Water-supply -- Developing countries -- Management , Infrastructure (Economics) -- Developing countries
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63276 , vital:73243
- Description: This study sought to assess the management of water services in the Fairview community within the Ixopo town under the Harry Gwala District Municipality (HGDM). The study was further motivated by the need to ascertain stakeholders’ perceptions on the response to water shortage challenges in the Fairview community, assess Fairview community members’ knowledge, and identify opportunities brought about by water shortages in this community. The study was anchored on the service quality model (SERVQUAL) as the theoretical framework. The research design of the study was exploratory and used both qualitative and quantitative methods. The target population of the study consisted of ordinary members of the Fairview community and managerial staff at the HGDM. The qualitative part of the study involved eight (n = 8) managerial employees at the municipality. In total, 120 questionnaires were despatched, and 110 were returned, which gave a 92% response rate for the quantitative part of the study. The questionnaire respondents were chosen by random sampling, while the interview respondents were chosen by purposive sampling. The quantitative data were analysed using descriptive and inferential statistics, while the qualitative data were analysed using applied thematic analysis. The study revealed that there is generally a negative perception of the municipal responses to addressing water supply challenges and that the municipality does not always act promptly to water supply challenges. Perceptions of poor-quality service provision regarding responsiveness, reliability, assurance, and empathy were found. The findings also revealed that the Fairview community members are generally knowledgeable about water conservation. The study unveiled opportunities for addressing water supply challenges, such as mobilising funds from stakeholders to build additional water reticulation, harvesting capacity, and modernisation of water management, and recommends that the municipality immediately conduct public participation meetings and citizen satisfaction surveys to ascertain community service delivery expectations, followed by developing service quality standards and performance agreements with municipal staff to improve residents’ perceptions of the municipality’s ability to respond to water supply challenges. , Thesis (MPA) -- Faculty of Humanities, School of Governmental and Social Sciences, 2024
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- Date Issued: 2024-04
Attitude of physical sciences teachers towards the role of formal assessment of practical work: a case study in Buffalo City metropolitan district in the Eastern Cape
- Authors: Mzinyane, Lindiwe
- Date: 2024-04
- Subjects: Physical sciences -- Study and teaching , Life sciences -- Study and teaching , Science -- Study and teaching -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64016 , vital:73639
- Description: The Curriculum and Assessment Policy Statement (CAPS) for Physical sciences in South African states that learners should carryout formal experiments Formal experiments contribute immensely to the development of laboratory skills and scientific knowledge, as well as understanding science concepts and theories. However, research shows that many teachers do not support and/or guide learners in formal experiments. The aim of this study was to explore and understand the attitude of Grade 11 Physical sciences teachers in Buffalo City Metropolitan District (BCM), in the Eastern Cape province regarding formal experiments. The TALIS framework was used to unpack teachers’ perceptions and understanding of formal experiments and related practical activities. A qualitative approach within the interpretative paradigm was employed in which an open-ended questionnaire and face to face interviews were conducted as data collection tools. The sample comprised ten participants (4 males and 6 females) of ages ranging from 20 to 54 years The data collection process involved three phases that included a pre-intervention questionnaire, an intervention workshop and post intervention face to face interview. Most of the participants 7(70%) confirmed that they did not carry out all formal experiments as prescribed in the CAPS document. The results revealed that most teachers do not understand the purpose of practical work and /or formal experiments, which is a possible explanation for the negative attitude towards the formal experiments teachers hold. The study also revealed that some participants 4(40%) did not understand the link between science pedagogy and the nature of science. It was discovered from the results that negative attitude towards formal experiments was due to lack of resources, lack of knowledge to guide learners to carry out the experiments, lack of time, and overcrowded classes. , Thesis (MEd) -- Faculty of Education, School of Postgraduate Education, 2024
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- Date Issued: 2024-04
Augmenting encoder-decoder networks for first-order logic formula parsing using attention pointer mechanisms
- Authors: Tissink, Kade
- Date: 2024-04
- Subjects: Translators (Computer programs) , Computational linguistics , Computer science
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/64390 , vital:73692
- Description: Semantic parsing is the task of extracting a structured machine-interpretable representation from natural language utterance. This representation can be used for various applications such as question answering, information extraction, and dialogue systems. However, semantic parsing is a challenging problem that requires dealing with the ambiguity, variability, and complexity of natural language. This dissertation investigates neural parsing of natural language (NL) sentences to first-order logic (FOL) formulas. FOL is a widely used formal language for expressing logical statements and reasoning. FOL formulas can capture the meaning and structure of natural language sentences in a precise and unambiguous way. The problem is initially approached as a sequence-to-sequence mapping task using both LSTM-based and transformer encoder-decoder architectures for character-, subword-, and wordlevel text tokenisation. These models are trained on NL-FOL datasets using supervised learning and evaluated on various metrics such as exact match accuracy, syntactic validity, formula structure accuracy, and predicate/constant similarity. A novel augmented model is then introduced that decomposes the task of neural FOL parsing into four inter-dependent subtasks: template decoding, predicate and constant recognition, predicate set pointing, and object set pointing. The components for the four subtasks are jointly trained using multi-task learning and evaluated using the same metrics from the sequence-tosequence models. The results indicate improved performance over the sequence-to-sequence models and the modular design allows for more interpretability and flexibility. Additionally, to compensate for the scarcity of open-source, labelled NL-FOL datasets, a new benchmark is constructed from publicly accessible data. The data consists of NL sentences paired with corresponding FOL formulas in a standardised notation. The data is split into training, validation, and test sets. The main contributions of this dissertation are: an in-depth literature review covering decades of research presented with a consistent notation, the formation of a complex NL-FOL benchmark that includes algorithmically generated and human-annotated FOL formulas, proposal of a novel transformer encoder-decoder architecture that is shown to successfully train at significant depths, evaluation of twenty sequence-to-sequence models on the task of neural FOL parsing for different text representations and encoder-decoder architectures, the proposal of a novel augmented FOL parsing architecture, and an in-depth analysis of the strengths and weaknesses of these models. , Thesis (MSc) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics , 2024
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- Date Issued: 2024-04
Augmenting the Moore-Penrose generalised Inverse to train neural networks
- Authors: Fang, Bobby
- Date: 2024-04
- Subjects: Neural networks (Computer science) , Machine learning , Mathematical optimization -- Computer programs
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63755 , vital:73595
- Description: An Extreme Learning Machine (ELM) is a non-iterative and fast feedforward neural network training algorithm which uses the Moore-Penrose generalised inverse of a matrix to compute the weights of the output layer of the neural network, using a random initialisation for the hidden layer. While ELM has been used to train feedforward neural networks, the effectiveness of the MP generalised to train recurrent neural networks is yet to be investigated. The primary aim of this research was to investigate how biases in the output layer and the MP generalised inverse can be used to train recurrent neural networks. To accomplish this, the Bias Augmented ELM (BA-ELM), which concatenated the hidden layer output matrix with a ones-column vector to simulate the biases in the output layer, was proposed. A variety of datasets generated from optimisation test functions, as well as using real-world regression and classification datasets, were used to validate BA-ELM. The results showed in specific circumstances that BA-ELM was able to perform better than ELM. Following this, Recurrent ELM (R-ELM) was proposed which uses a recurrent hidden layer instead of a feedforward hidden layer. Recurrent neural networks also rely on having functional feedback connections in the recurrent layer. A hybrid training algorithm, Recurrent Hybrid ELM (R-HELM), was proposed, which uses a gradient-based algorithm to optimise the recurrent layer and the MP generalised inverse to compute the output weights. The evaluation of R-ELM and R-HELM algorithms were carried out using three different recurrent architectures on two recurrent tasks derived from the Susceptible- Exposed-Infected-Removed (SEIR) epidemiology model. Various training hyperparameters were evaluated through hyperparameter investigations to investigate their effectiveness on the hybrid training algorithm. With optimal hyperparameters, the hybrid training algorithm was able to achieve better performance than the conventional gradient-based algorithm. , Thesis (MSc) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2024
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- Date Issued: 2024-04
Community perceptions on teenage pregnancy: the case of Kamvelihle Township in Nelson Mandela Bay Municipality
- Authors: Mtakati, Faith
- Date: 2024-04
- Subjects: Teenage pregnancy -- South Africa -- Port Elizabeth , Teenage mothers -- South Africa -- Port Elizabeth , Teenagers -- Sexual behavior
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63368 , vital:73263
- Description: Increasingly, teenagers in South Africa get pregnant while studying and this disrupt their schooling program. The above problem in many instances ended up affecting their performance at school and they drop-out of the school. This study investigates the community perceptions on teenage pregnancy in Kamvelihle Township. The study objectives are as follows: to investigate the community perception on teenage pregnancy in Kamvelihle Township, to contribute within the South African Sociological field with specific reference to Kamvelihle Township in the Eastern Cape and to come up with the recommendations with the view to addressing some of the problem in Kamvelihle Township. The research methodology employed in this study is qualitative in approach and it included amongst others, individual interviews using an interview guide containing relevant questions posed to participants. Research ethics protocol has been adhered to from the initial up to the last stages of the study. To supplement the above, relevant secondary sources were consulted ranging from scholarly journal articles as well as scholarly books including other available reading material. In this study, sex education has been used as a conceptual framework to understand the problem of teenage pregnancy in Kamvelihle Township. , Thesis (MA) -- Faculty of Humanities, School of Governmental and Social Sciences, 2024
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- Date Issued: 2024-04