A multinational study of authors’ perceptions of and practical approaches to writing geography textbooks:
- Lee, Jongwon, Catling, Simon, Kidman, Gillian, Bednarz, Robert, Krause, Uwe, Martija, Andoni A, Ohnishi, Koji, Wilmot, P Dianne, Zecha, Stefane
- Authors: Lee, Jongwon , Catling, Simon , Kidman, Gillian , Bednarz, Robert , Krause, Uwe , Martija, Andoni A , Ohnishi, Koji , Wilmot, P Dianne , Zecha, Stefane
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158269 , vital:40168 , https://doi.org/10.1080/10382046.2020.1743931
- Description: Like all school textbooks, geography textbooks are authored. Almost all textbook research in and beyond geography has neglected their authors. This questionnaire-based multinational research project investigated the perceptions of 71 primary and secondary school geography textbook authors from seven countries in five continents. Though not intended as a definitive study, the findings identified several values and areas of expertise which many textbook authors in different countries held to be important for their work.
- Full Text:
- Date Issued: 2020
- Authors: Lee, Jongwon , Catling, Simon , Kidman, Gillian , Bednarz, Robert , Krause, Uwe , Martija, Andoni A , Ohnishi, Koji , Wilmot, P Dianne , Zecha, Stefane
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158269 , vital:40168 , https://doi.org/10.1080/10382046.2020.1743931
- Description: Like all school textbooks, geography textbooks are authored. Almost all textbook research in and beyond geography has neglected their authors. This questionnaire-based multinational research project investigated the perceptions of 71 primary and secondary school geography textbook authors from seven countries in five continents. Though not intended as a definitive study, the findings identified several values and areas of expertise which many textbook authors in different countries held to be important for their work.
- Full Text:
- Date Issued: 2020
Charlie Hebdo as a critical event in a secondary school: Muslim students’ complex positioning in relation to the attack
- Tize, Carola, Berckmoes, Lidewyde, de Jong, Joop, Reis, Ria
- Authors: Tize, Carola , Berckmoes, Lidewyde , de Jong, Joop , Reis, Ria
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156400 , vital:39986 , DOI: 10.1177/1363461520903814
- Description: This paper examines responses to the 2015 terror attack on Charlie Hebdo, a French satirical magazine, amongst students in a secondary school in Berlin-Neukölln, Germany. The Charlie Hebdo attack occurred in the final weeks of a 19-month ethnographic study in the community. By analyzing the responses in the school to this critical event, we identify what is at stake for Muslim students.
- Full Text:
- Date Issued: 2020
- Authors: Tize, Carola , Berckmoes, Lidewyde , de Jong, Joop , Reis, Ria
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156400 , vital:39986 , DOI: 10.1177/1363461520903814
- Description: This paper examines responses to the 2015 terror attack on Charlie Hebdo, a French satirical magazine, amongst students in a secondary school in Berlin-Neukölln, Germany. The Charlie Hebdo attack occurred in the final weeks of a 19-month ethnographic study in the community. By analyzing the responses in the school to this critical event, we identify what is at stake for Muslim students.
- Full Text:
- Date Issued: 2020
Debunking the myth of lack of vocabulary for teaching content knowledge in primary schools: exploring terminology for science in Ekegusii of Kenya
- Authors: Mose, Peter
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150095 , vital:38939 , DOI: 10.1080/02572117.2020.1733827
- Description: The language-in-education policy to teach in mother tongues at lower primary level is not adhered to by classroom teachers in Kenya due to, among other reasons, lack of content terminology. The purpose of this study was to demonstrate that mother tongues can be used to teach science up to the end of grade three, considering the nature of topics for this level and other extra-classroom realities. Our research objectives were to examine the nature and content of science topics and sub-topics from grade one to grade three; examine conceptual and technical terms in grade one to grade three science textbooks; describe the Ekegusii equivalents of these terms; and explain the feasibility of teaching science in Ekegusii up to the end of grade three.
- Full Text:
- Date Issued: 2020
- Authors: Mose, Peter
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150095 , vital:38939 , DOI: 10.1080/02572117.2020.1733827
- Description: The language-in-education policy to teach in mother tongues at lower primary level is not adhered to by classroom teachers in Kenya due to, among other reasons, lack of content terminology. The purpose of this study was to demonstrate that mother tongues can be used to teach science up to the end of grade three, considering the nature of topics for this level and other extra-classroom realities. Our research objectives were to examine the nature and content of science topics and sub-topics from grade one to grade three; examine conceptual and technical terms in grade one to grade three science textbooks; describe the Ekegusii equivalents of these terms; and explain the feasibility of teaching science in Ekegusii up to the end of grade three.
- Full Text:
- Date Issued: 2020
Decolonisation as a spatial question: the student accommodation crisis and Higher Education transformation
- Mzileni, Pedro, Mkhize, Nomalanga
- Authors: Mzileni, Pedro , Mkhize, Nomalanga
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156378 , vital:39984 , DOI: 10.1080/21528586.2020.1733649
- Description: Debates on epistemological decolonisation have focused on curriculum issues. There has not been sufficient analysis of how questions of decolonisation are shaped by other factors, such as the very spatial location of universities. This article argues that the colonial nature of the university in South Africa is directly linked spatially to the historic land question of dispossession in South Africa. Historically, South African universities came to be fixed as physical and cultural elements of towns and cities based on the broader trajectory of settler-colonialism and apartheid urban development, segregation and the Group Areas logic of the apartheid state.
- Full Text:
- Date Issued: 2020
- Authors: Mzileni, Pedro , Mkhize, Nomalanga
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156378 , vital:39984 , DOI: 10.1080/21528586.2020.1733649
- Description: Debates on epistemological decolonisation have focused on curriculum issues. There has not been sufficient analysis of how questions of decolonisation are shaped by other factors, such as the very spatial location of universities. This article argues that the colonial nature of the university in South Africa is directly linked spatially to the historic land question of dispossession in South Africa. Historically, South African universities came to be fixed as physical and cultural elements of towns and cities based on the broader trajectory of settler-colonialism and apartheid urban development, segregation and the Group Areas logic of the apartheid state.
- Full Text:
- Date Issued: 2020
Deep phylogeographic structure may indicate cryptic species within the Sparid genus Spondyliosoma:
- McKeown, Niall J, Gwilliam, Michael P, Healey, Amy J E, Skujina, Ilze, Potts, Warren M, Sauer, Warwick H H, Shaw, Paul W
- Authors: McKeown, Niall J , Gwilliam, Michael P , Healey, Amy J E , Skujina, Ilze , Potts, Warren M , Sauer, Warwick H H , Shaw, Paul W
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158085 , vital:40147 , DOI: 10.1111/jfb.14316
- Description: Two geographically nonoverlapping species are currently described within the sparid genus Spondyliosoma: Spondyliosoma cantharus (Black Seabream) occurring across Mediterranean and eastern Atlantic waters from NW Europe to Angola and S. emarginatum (Steentjie) considered endemic to southern Africa. To address prominent knowledge gaps this study investigated range‐wide phylogeographic structure across both species. Mitochondrial DNA sequences revealed deep phylogeographic structuring with four regionally partitioned reciprocally monophyletic clades, a Mediterranean clade and three more closely related Atlantic clades [NE Atlantic, Angola and South Africa (corresponding to S. emarginatum)]. Divergence and distribution of the lineages reflects survival in, and expansion from, disjunct glacial refuge areas. Cytonuclear differentiation of S. emarginatum supports its validity as a distinct species endemic to South African waters.
- Full Text:
- Date Issued: 2020
- Authors: McKeown, Niall J , Gwilliam, Michael P , Healey, Amy J E , Skujina, Ilze , Potts, Warren M , Sauer, Warwick H H , Shaw, Paul W
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158085 , vital:40147 , DOI: 10.1111/jfb.14316
- Description: Two geographically nonoverlapping species are currently described within the sparid genus Spondyliosoma: Spondyliosoma cantharus (Black Seabream) occurring across Mediterranean and eastern Atlantic waters from NW Europe to Angola and S. emarginatum (Steentjie) considered endemic to southern Africa. To address prominent knowledge gaps this study investigated range‐wide phylogeographic structure across both species. Mitochondrial DNA sequences revealed deep phylogeographic structuring with four regionally partitioned reciprocally monophyletic clades, a Mediterranean clade and three more closely related Atlantic clades [NE Atlantic, Angola and South Africa (corresponding to S. emarginatum)]. Divergence and distribution of the lineages reflects survival in, and expansion from, disjunct glacial refuge areas. Cytonuclear differentiation of S. emarginatum supports its validity as a distinct species endemic to South African waters.
- Full Text:
- Date Issued: 2020
Detection of the in vitro modulation of Plasmodium falciparum Arf1 by Sec7 and ArfGAP domains using a colorimetric plate-based assay:
- Swart, Tarryn, Khan, Farrah D, Ntlantsana, Apelele, Laming, Dustin, Veale, Clinton G L, Przyborski, Jude M, Edkins, Adrienne L, Hoppe, Heinrich C
- Authors: Swart, Tarryn , Khan, Farrah D , Ntlantsana, Apelele , Laming, Dustin , Veale, Clinton G L , Przyborski, Jude M , Edkins, Adrienne L , Hoppe, Heinrich C
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165418 , vital:41242 , https://0-doi.org.wam.seals.ac.za/10.1038/s41598-020-61101-3
- Description: The regulation of human Arf1 GTPase activity by ArfGEFs that stimulate GDP/GTP exchange and ArfGAPs that mediate GTP hydrolysis has attracted attention for the discovery of Arf1 inhibitors as potential anti-cancer agents. The malaria parasite Plasmodium falciparum encodes a Sec7 domain-containing protein - presumably an ArfGEF - and two putative ArfGAPs, as well as an Arf1 homologue (PfArf1) that is essential for blood-stage parasite viability. However, ArfGEF and ArfGAP-mediated activation/deactivation of PfArf1 has not been demonstrated.
- Full Text:
- Date Issued: 2020
- Authors: Swart, Tarryn , Khan, Farrah D , Ntlantsana, Apelele , Laming, Dustin , Veale, Clinton G L , Przyborski, Jude M , Edkins, Adrienne L , Hoppe, Heinrich C
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165418 , vital:41242 , https://0-doi.org.wam.seals.ac.za/10.1038/s41598-020-61101-3
- Description: The regulation of human Arf1 GTPase activity by ArfGEFs that stimulate GDP/GTP exchange and ArfGAPs that mediate GTP hydrolysis has attracted attention for the discovery of Arf1 inhibitors as potential anti-cancer agents. The malaria parasite Plasmodium falciparum encodes a Sec7 domain-containing protein - presumably an ArfGEF - and two putative ArfGAPs, as well as an Arf1 homologue (PfArf1) that is essential for blood-stage parasite viability. However, ArfGEF and ArfGAP-mediated activation/deactivation of PfArf1 has not been demonstrated.
- Full Text:
- Date Issued: 2020
Dimensions and indicators of non-profit financial condition: evidence from South African public universities
- Authors: Bunting, Mark B
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150296 , vital:38965 , DOI: https://doi.org/10.4102/sajems.v23i1.2974
- Description: More than three decades of research have failed to achieve convergence on a method for the measurement of non-profit financial condition, with the literature reporting a bewildering array of financial dimensions, and more than 100 ratios and indicators. This article offers a contribution to a broader discourse in non-profit financial analysis by recognising, and taking action in response to, the potential threat to research validity arising from the generally unchallenged presumption that accounting numbers provide a complete, unbiased and error-free representation of an entity’s underlying economic reality.
- Full Text:
- Date Issued: 2020
- Authors: Bunting, Mark B
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150296 , vital:38965 , DOI: https://doi.org/10.4102/sajems.v23i1.2974
- Description: More than three decades of research have failed to achieve convergence on a method for the measurement of non-profit financial condition, with the literature reporting a bewildering array of financial dimensions, and more than 100 ratios and indicators. This article offers a contribution to a broader discourse in non-profit financial analysis by recognising, and taking action in response to, the potential threat to research validity arising from the generally unchallenged presumption that accounting numbers provide a complete, unbiased and error-free representation of an entity’s underlying economic reality.
- Full Text:
- Date Issued: 2020
Effects of an eight-week lumbar stabilization exercise programme on selected variables of patients with chronic low back pain:
- Abass, Ademola O, Alli, Abiola R, Olagbegi, Oladapo M, Christie, Candice J, Bolarinde, Olufemi S
- Authors: Abass, Ademola O , Alli, Abiola R , Olagbegi, Oladapo M , Christie, Candice J , Bolarinde, Olufemi S
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150307 , vital:38966 , DOI: https://doi.org/10.3329/bjms.v19i3.45864
- Description: Lumbar stabilisation exercise has been shown to reduce pain and disability in patients with low back pain but information on its potential benefits in term of back muscle endurance is scarce. This study was aimed at investigating the effects of augmenting conventional physiotherapy with lumbar stabilization exercises on selected variables of patients with non-specific chronic low back pain (NSCLBP).
- Full Text:
- Date Issued: 2020
- Authors: Abass, Ademola O , Alli, Abiola R , Olagbegi, Oladapo M , Christie, Candice J , Bolarinde, Olufemi S
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150307 , vital:38966 , DOI: https://doi.org/10.3329/bjms.v19i3.45864
- Description: Lumbar stabilisation exercise has been shown to reduce pain and disability in patients with low back pain but information on its potential benefits in term of back muscle endurance is scarce. This study was aimed at investigating the effects of augmenting conventional physiotherapy with lumbar stabilization exercises on selected variables of patients with non-specific chronic low back pain (NSCLBP).
- Full Text:
- Date Issued: 2020
Flower orientation in Gloriosa superba (Colchicaceae) promotes cross-pollination via butterfly wings:
- Daniels, Ryan J, Johnson, Steven D, Peter, Craig I
- Authors: Daniels, Ryan J , Johnson, Steven D , Peter, Craig I
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150141 , vital:38943 , https://0-doi.org.wam.seals.ac.za/10.1093/aob/mcaa048
- Description: Complex modifications of angiosperm flowers often function for precise pollen placement on pollinators and to promote cross-pollination. We explore the functional significance of the unusually elaborate morphology of Gloriosa superba flowers, which are divided into one hermaphrodite meranthium and five male meranthia (functional pollination units of a single flower). We used controlled pollination experiments, floral measurements, pollen load analyses and visitor observations in four populations of G. superba in South Africa to determine the breeding system, mechanism of pollination and role of flower in the promotion of cross-pollination.
- Full Text:
- Date Issued: 2020
- Authors: Daniels, Ryan J , Johnson, Steven D , Peter, Craig I
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150141 , vital:38943 , https://0-doi.org.wam.seals.ac.za/10.1093/aob/mcaa048
- Description: Complex modifications of angiosperm flowers often function for precise pollen placement on pollinators and to promote cross-pollination. We explore the functional significance of the unusually elaborate morphology of Gloriosa superba flowers, which are divided into one hermaphrodite meranthium and five male meranthia (functional pollination units of a single flower). We used controlled pollination experiments, floral measurements, pollen load analyses and visitor observations in four populations of G. superba in South Africa to determine the breeding system, mechanism of pollination and role of flower in the promotion of cross-pollination.
- Full Text:
- Date Issued: 2020
PKS 2250−351: A Giant Radio Galaxy in Abell 3936
- Seymour, N, Huynh, M, Shabala, S S, Rogers, J, Davies, L J M, Turner, R J, O'Brien, A, Ishwara-Chandra, C H, Thorne, J E, Galvin, T J, Jarrett, T, Anderbach, H, Anderson, A, Bunton, J, Chow, K, Collier, J D, Driver, S, Filipovic, M D, Gurkan, G, Hopkins, A M, Kapinska, A D, Leahy, D A, Marvil, J, Manojlovic, P, Norris, R P, Phillips, C, Robotham, A, Rudnick, L, Singh, V, White, S V
- Authors: Seymour, N , Huynh, M , Shabala, S S , Rogers, J , Davies, L J M , Turner, R J , O'Brien, A , Ishwara-Chandra, C H , Thorne, J E , Galvin, T J , Jarrett, T , Anderbach, H , Anderson, A , Bunton, J , Chow, K , Collier, J D , Driver, S , Filipovic, M D , Gurkan, G , Hopkins, A M , Kapinska, A D , Leahy, D A , Marvil, J , Manojlovic, P , Norris, R P , Phillips, C , Robotham, A , Rudnick, L , Singh, V , White, S V
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150320 , vital:38967 , https://doi.org/10.1017/pasa.2019.49
- Description: We present a detailed analysis of the radio galaxy PKS , a giant of 1.2 Mpc projected size, its host galaxy, and its environment. We use radio data from the Murchison Widefield Array, the upgraded Giant Metre-wavelength Radio Telescope, the Australian Square Kilometre Array Pathfinder, and the Australia Telescope Compact Array to model the jet power and age. Optical and IR data come from the Galaxy And Mass Assembly (GAMA) survey and provide information on the host galaxy and environment.
- Full Text:
- Date Issued: 2020
- Authors: Seymour, N , Huynh, M , Shabala, S S , Rogers, J , Davies, L J M , Turner, R J , O'Brien, A , Ishwara-Chandra, C H , Thorne, J E , Galvin, T J , Jarrett, T , Anderbach, H , Anderson, A , Bunton, J , Chow, K , Collier, J D , Driver, S , Filipovic, M D , Gurkan, G , Hopkins, A M , Kapinska, A D , Leahy, D A , Marvil, J , Manojlovic, P , Norris, R P , Phillips, C , Robotham, A , Rudnick, L , Singh, V , White, S V
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150320 , vital:38967 , https://doi.org/10.1017/pasa.2019.49
- Description: We present a detailed analysis of the radio galaxy PKS , a giant of 1.2 Mpc projected size, its host galaxy, and its environment. We use radio data from the Murchison Widefield Array, the upgraded Giant Metre-wavelength Radio Telescope, the Australian Square Kilometre Array Pathfinder, and the Australia Telescope Compact Array to model the jet power and age. Optical and IR data come from the Galaxy And Mass Assembly (GAMA) survey and provide information on the host galaxy and environment.
- Full Text:
- Date Issued: 2020
Potential of soil seed bank and ungulate-mediated endozoochory in old field restoration:
- Authors: Ruwanza, Sheunesu
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150216 , vital:38950 , https://0-muse.jhu.edu.wam.seals.ac.za/article/750319/pdf
- Description: Soil seed bank plays a key role in old field restoration because it provides information about plant species that may regenerate (Hopfensperger 2007). Most studies on old field restoration have concentrated on floristic similarities between soil seed bank and standing vegetation (Török et al. 2018). However, investigating the effects of proximity to natural/old field edge (habitat fragmentation border) on soil seed bank could yield better recovery predictions. Proximity to natural/old field edge may favour recruitment of a different plant community than that found in the old field interior. This due to favorable abiotic (e.g., soil moisture) and biotic (e.g., seed dispersal) microenvironments created near the edge. On the other hand, ungulate-mediated endozoochory has been shown to potentially facilitate ecological restoration in degraded systems, given that ungulates disperse diaspores across different landscapes (Baltzinger et al. 2019). However, ungulate-mediated endozoochory dispersal in degraded old fields is affected by several factors that include availability of nearby natural perches that attract dispersers, structural vegetation complexities, presence of food especially fruits, and feeding regimes (Baltzinger et al. 2019).
- Full Text:
- Date Issued: 2020
- Authors: Ruwanza, Sheunesu
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150216 , vital:38950 , https://0-muse.jhu.edu.wam.seals.ac.za/article/750319/pdf
- Description: Soil seed bank plays a key role in old field restoration because it provides information about plant species that may regenerate (Hopfensperger 2007). Most studies on old field restoration have concentrated on floristic similarities between soil seed bank and standing vegetation (Török et al. 2018). However, investigating the effects of proximity to natural/old field edge (habitat fragmentation border) on soil seed bank could yield better recovery predictions. Proximity to natural/old field edge may favour recruitment of a different plant community than that found in the old field interior. This due to favorable abiotic (e.g., soil moisture) and biotic (e.g., seed dispersal) microenvironments created near the edge. On the other hand, ungulate-mediated endozoochory has been shown to potentially facilitate ecological restoration in degraded systems, given that ungulates disperse diaspores across different landscapes (Baltzinger et al. 2019). However, ungulate-mediated endozoochory dispersal in degraded old fields is affected by several factors that include availability of nearby natural perches that attract dispersers, structural vegetation complexities, presence of food especially fruits, and feeding regimes (Baltzinger et al. 2019).
- Full Text:
- Date Issued: 2020
PRECEPT: a framework for ethical digital forensics investigations
- Ferguson, R I, Renaud, Karen, Wilford, Sara, Irons, Alastair
- Authors: Ferguson, R I , Renaud, Karen , Wilford, Sara , Irons, Alastair
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149884 , vital:38909 , https://doi.org/10.1108/JIC-05-2019-00979
- Description: This paper argues the need for a practical, ethically grounded approach to digital forensic investigations, one that acknowledges and respects the privacy rights of individuals and the intellectual capital disclosure rights of organizations, as well as acknowledging the needs of law enforcement. The paper derives a set of ethical guidelines, and then maps these onto a forensics investigation framework. The framework to expert review in two stages is subjected, refining the framework after each stage. The paper concludes by proposing the refined ethically grounded digital forensics investigation framework. The treatise is primarily UK based, but the concepts presented here have international relevance and applicability.
- Full Text:
- Date Issued: 2020
- Authors: Ferguson, R I , Renaud, Karen , Wilford, Sara , Irons, Alastair
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149884 , vital:38909 , https://doi.org/10.1108/JIC-05-2019-00979
- Description: This paper argues the need for a practical, ethically grounded approach to digital forensic investigations, one that acknowledges and respects the privacy rights of individuals and the intellectual capital disclosure rights of organizations, as well as acknowledging the needs of law enforcement. The paper derives a set of ethical guidelines, and then maps these onto a forensics investigation framework. The framework to expert review in two stages is subjected, refining the framework after each stage. The paper concludes by proposing the refined ethically grounded digital forensics investigation framework. The treatise is primarily UK based, but the concepts presented here have international relevance and applicability.
- Full Text:
- Date Issued: 2020
Radio and X-ray detections of GX 339–4 in quiescence using MeerKAT and Swift:
- Tremou, E, Corbel, S, Fender, R P, Woudt, P A, Miller-Jones, J C A, Motta, S E, Heywood, I, Armstrong, R P, Groot, P, Horesh, A, Van der Horst, A J, Koerding, E, Mooley, K P, Rowlinson, A, Wijers, R A M
- Authors: Tremou, E , Corbel, S , Fender, R P , Woudt, P A , Miller-Jones, J C A , Motta, S E , Heywood, I , Armstrong, R P , Groot, P , Horesh, A , Van der Horst, A J , Koerding, E , Mooley, K P , Rowlinson, A , Wijers, R A M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149862 , vital:38907 , https://0-doi.org.wam.seals.ac.za/10.1093/mnrasl/slaa019
- Description: The radio–X-ray correlation that characterizes accreting black holes at all mass scales – from stellar mass black holes in binary systems to supermassive black holes powering active galactic nuclei – is one of the most important pieces of observational evidence supporting the existence of a connection between the accretion process and the generation of collimated outflows – or jets – in accreting systems. Although recent studies suggest that the correlation extends down to low luminosities, only a handful of stellar mass black holes have been clearly detected, and in general only upper limits (especially at radio wavelengths) can be obtained during quiescence. We recently obtained detections of the black hole X-ray binary (XRB) GX 339–4 in quiescence using the Meer Karoo Array Telescope (MeerKAT) radio telescope and Swift X-ray Telescope instrument on board the Neil Gehrels Swift Observatory, probing the lower end of the radio–X-ray correlation. We present the properties of accretion and of the connected generation of jets in the poorly studied low-accretion rate regime for this canonical black hole XRB system.
- Full Text:
- Date Issued: 2020
- Authors: Tremou, E , Corbel, S , Fender, R P , Woudt, P A , Miller-Jones, J C A , Motta, S E , Heywood, I , Armstrong, R P , Groot, P , Horesh, A , Van der Horst, A J , Koerding, E , Mooley, K P , Rowlinson, A , Wijers, R A M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149862 , vital:38907 , https://0-doi.org.wam.seals.ac.za/10.1093/mnrasl/slaa019
- Description: The radio–X-ray correlation that characterizes accreting black holes at all mass scales – from stellar mass black holes in binary systems to supermassive black holes powering active galactic nuclei – is one of the most important pieces of observational evidence supporting the existence of a connection between the accretion process and the generation of collimated outflows – or jets – in accreting systems. Although recent studies suggest that the correlation extends down to low luminosities, only a handful of stellar mass black holes have been clearly detected, and in general only upper limits (especially at radio wavelengths) can be obtained during quiescence. We recently obtained detections of the black hole X-ray binary (XRB) GX 339–4 in quiescence using the Meer Karoo Array Telescope (MeerKAT) radio telescope and Swift X-ray Telescope instrument on board the Neil Gehrels Swift Observatory, probing the lower end of the radio–X-ray correlation. We present the properties of accretion and of the connected generation of jets in the poorly studied low-accretion rate regime for this canonical black hole XRB system.
- Full Text:
- Date Issued: 2020
Species-specific plastic accumulation in the sediment and canopy of coastal vegetated habitats:
- Cozzolino, Lorenzo, Nicastro, Katy R, Zardi, Gerardo I, de los Santos, Carmen B
- Authors: Cozzolino, Lorenzo , Nicastro, Katy R , Zardi, Gerardo I , de los Santos, Carmen B
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149410 , vital:38848 , https://doi.org/10.1016/j.scitotenv.2020.138018
- Description: Plastic waste has become ubiquitous in ecosystems worldwide. Few, recent studies report evidence of coastal vegetated habitats acting as sink for plastics, yet assessments have been completed either for macro or microplastics and focussing on just one type of vegetated habitat.
- Full Text:
- Date Issued: 2020
- Authors: Cozzolino, Lorenzo , Nicastro, Katy R , Zardi, Gerardo I , de los Santos, Carmen B
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149410 , vital:38848 , https://doi.org/10.1016/j.scitotenv.2020.138018
- Description: Plastic waste has become ubiquitous in ecosystems worldwide. Few, recent studies report evidence of coastal vegetated habitats acting as sink for plastics, yet assessments have been completed either for macro or microplastics and focussing on just one type of vegetated habitat.
- Full Text:
- Date Issued: 2020
STIP1/HOP regulates the actin cytoskeleton through interactions with actin and changes in actin-binding proteins cofilin and profilin:
- Beckley, Samantha Joy, Hunter, Morgan C, Kituyi, Sarah N, Wingate, Ianthe, Chakraborty, Abantika, Schwarz, Kelly, Makhubu, Matodzi P, Rousseau, Robert P, Ruck, Duncan K, de la Mare, Jo-Anne, Blatch, Gregory L, Edkins, Adrienne L
- Authors: Beckley, Samantha Joy , Hunter, Morgan C , Kituyi, Sarah N , Wingate, Ianthe , Chakraborty, Abantika , Schwarz, Kelly , Makhubu, Matodzi P , Rousseau, Robert P , Ruck, Duncan K , de la Mare, Jo-Anne , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165373 , vital:41238 , https://doi.org/10.3390/ijms21093152
- Description: Cell migration plays a vital role in both health and disease. It is driven by reorganization of the actin cytoskeleton, which is regulated by actin-binding proteins cofilin and profilin. Stress-inducible phosphoprotein 1 (STIP1) is a well-described co-chaperone of the Hsp90 chaperone system, and our findings identify a potential regulatory role of STIP1 in actin dynamics. We show that STIP1 can be isolated in complex with actin and Hsp90 from HEK293T cells and directly interacts with actin in vitro via the C-terminal TPR2AB-DP2 domain of STIP1, potentially due to a region spanning two putative actin-binding motifs. We found that STIP1 could stimulate the in vitro ATPase activity of actin, suggesting a potential role in the modulation of F-actin formation. Interestingly, while STIP1 depletion in HEK293T cells had no major effect on total actin levels, it led to increased nuclear accumulation of actin, disorganization of F-actin structures, and an increase and decrease in cofilin and profilin levels, respectively. This study suggests that STIP1 regulates the cytoskeleton by interacting with actin, or via regulating the ratio of proteins known to affect actin dynamics.
- Full Text:
- Date Issued: 2020
- Authors: Beckley, Samantha Joy , Hunter, Morgan C , Kituyi, Sarah N , Wingate, Ianthe , Chakraborty, Abantika , Schwarz, Kelly , Makhubu, Matodzi P , Rousseau, Robert P , Ruck, Duncan K , de la Mare, Jo-Anne , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165373 , vital:41238 , https://doi.org/10.3390/ijms21093152
- Description: Cell migration plays a vital role in both health and disease. It is driven by reorganization of the actin cytoskeleton, which is regulated by actin-binding proteins cofilin and profilin. Stress-inducible phosphoprotein 1 (STIP1) is a well-described co-chaperone of the Hsp90 chaperone system, and our findings identify a potential regulatory role of STIP1 in actin dynamics. We show that STIP1 can be isolated in complex with actin and Hsp90 from HEK293T cells and directly interacts with actin in vitro via the C-terminal TPR2AB-DP2 domain of STIP1, potentially due to a region spanning two putative actin-binding motifs. We found that STIP1 could stimulate the in vitro ATPase activity of actin, suggesting a potential role in the modulation of F-actin formation. Interestingly, while STIP1 depletion in HEK293T cells had no major effect on total actin levels, it led to increased nuclear accumulation of actin, disorganization of F-actin structures, and an increase and decrease in cofilin and profilin levels, respectively. This study suggests that STIP1 regulates the cytoskeleton by interacting with actin, or via regulating the ratio of proteins known to affect actin dynamics.
- Full Text:
- Date Issued: 2020
Synthesis of pH sensitive dual capped CdTe QDs: their optical properties and structural morphology
- Daramola, Olamide A, Noundou, Xavier S, Nkanga, Christian I, Tseki, Potlaki F, Krause, Rui W M
- Authors: Daramola, Olamide A , Noundou, Xavier S , Nkanga, Christian I , Tseki, Potlaki F , Krause, Rui W M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156364 , vital:39983 , https://doi.org/10.1007/s10895-020-02526-x
- Description: We herein report five different types of thiol dual capped cadmium tellurite quantum dots (CdTe QDs) namely glutathionemercapto-propanoic acid (QD 1), glutathione-thiolglycolic acid (QD 2), L-cysteine-mercapto-propanoic acid (QD 3), L-cysteinethiol-glycolic acid (QD 4) and mercapto-propanoic acid-thiol-glycolic (QD 5). Dual-capped CdTe QDs were prepared using a one pot synthetic method. Cadmium acetate and sodium tellurite were respectively used as cadmium and tellurium precursors. Photo-physical properties of the synthesized QDs were examined using UV-Vis and photoluminescence spectroscopy while structural characterization was performed by means of transmission electron microscopy (TEM) and Fourier transform infrared (FTIR) spectroscopy.
- Full Text:
- Date Issued: 2020
- Authors: Daramola, Olamide A , Noundou, Xavier S , Nkanga, Christian I , Tseki, Potlaki F , Krause, Rui W M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156364 , vital:39983 , https://doi.org/10.1007/s10895-020-02526-x
- Description: We herein report five different types of thiol dual capped cadmium tellurite quantum dots (CdTe QDs) namely glutathionemercapto-propanoic acid (QD 1), glutathione-thiolglycolic acid (QD 2), L-cysteine-mercapto-propanoic acid (QD 3), L-cysteinethiol-glycolic acid (QD 4) and mercapto-propanoic acid-thiol-glycolic (QD 5). Dual-capped CdTe QDs were prepared using a one pot synthetic method. Cadmium acetate and sodium tellurite were respectively used as cadmium and tellurium precursors. Photo-physical properties of the synthesized QDs were examined using UV-Vis and photoluminescence spectroscopy while structural characterization was performed by means of transmission electron microscopy (TEM) and Fourier transform infrared (FTIR) spectroscopy.
- Full Text:
- Date Issued: 2020
The In Silico Prediction of hotspot residues that contribute to the structural stability of subunit interfaces of a Picornavirus Capsid:
- Upfold, Nicole, Ross, Caroline J, Tastan Bishop, Özlem, Knox, Caroline M
- Authors: Upfold, Nicole , Ross, Caroline J , Tastan Bishop, Özlem , Knox, Caroline M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149970 , vital:38919 , https://doi.org/10.3390/v12040387
- Description: The assembly of picornavirus capsids proceeds through the stepwise oligomerization of capsid protein subunits and depends on interactions between critical residues known as hotspots. Few studies have described the identification of hotspot residues at the protein subunit interfaces of the picornavirus capsid, some of which could represent novel drug targets. Using a combination of accessible web servers for hotspot prediction, we performed a comprehensive bioinformatic analysis of the hotspot residues at the intraprotomer, interprotomer and interpentamer interfaces of the Theiler’s murine encephalomyelitis virus (TMEV) capsid.
- Full Text:
- Date Issued: 2020
- Authors: Upfold, Nicole , Ross, Caroline J , Tastan Bishop, Özlem , Knox, Caroline M
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149970 , vital:38919 , https://doi.org/10.3390/v12040387
- Description: The assembly of picornavirus capsids proceeds through the stepwise oligomerization of capsid protein subunits and depends on interactions between critical residues known as hotspots. Few studies have described the identification of hotspot residues at the protein subunit interfaces of the picornavirus capsid, some of which could represent novel drug targets. Using a combination of accessible web servers for hotspot prediction, we performed a comprehensive bioinformatic analysis of the hotspot residues at the intraprotomer, interprotomer and interpentamer interfaces of the Theiler’s murine encephalomyelitis virus (TMEV) capsid.
- Full Text:
- Date Issued: 2020
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