- Title
- Comparative studies of different ant-hypertensive treatments used for cardiovascular disease patients : a case study of public health facility in the Eastern Cape South Africa
- Creator
- Abiodun, Oluwatoyin Victoria
- Subject
- Survival analysis (Biometry) Cardiovascular system -- Diseases
- Date
- 2017
- Type
- Thesis
- Type
- Masters
- Type
- MSc
- Identifier
- http://hdl.handle.net/10353/13205
- Identifier
- vital:39519
- Description
- Discovery has shown that many deaths arising from cardiovascular disease often show early symptoms of high blood pressure, which makes it the leading risk factor of cardiovascular diseases. There is a distressing rate of 970 million hypertensive patients worldwide, a higher ratio of 640 million are from developing countries, if proper measures are not taken, there will be a higher growth of cardiovascular disease in adults by 2025. The focus of this study was to compare the therapeutic potentials of the anti-hypertensive therapies, drug A (amiloride + furosemide) and drug B (hydrochlorothiazide + enalapril) used in the treatment of cardiovascular disease patients for their capability to lengthen remission duration and survival time. All patients were diagnosed with a type of cardiovascular disorder, therefore patient records were followed up and blood pressure was being monitored for a period of two years. The retrospective data gotten from the public health facility was analysed using survival analysis methods. The results revealed that there was no statistical significance in the distributions of the length of remission and survival time of drug A and drug B patients. Also, in the age category, CVD patients that are 55 and above recover faster with drug A, while CVD patients below 55 shows a better survival with drug B. Then again, estimates from the gender category show a better survival in males using drug A, while the females thrive slightly better using drug B. Among all the risk factors considered in the study, only employment status showed a strong impact on survival time (remission). The findings from this study may help to formulate interventions and strategies that will increase the lifespan of cardiovascular patients and reduce early mortality due to cardiovascular diseases.
- Format
- 106 leaves
- Format
- Publisher
- University of Fort Hare
- Publisher
- Faculty of Science and Agriculture
- Language
- English
- Rights
- University of Fort Hare
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| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | MSc (Biostats & Epidemiology) - DISSERTATION (201402230).pdf | 1 MB | Adobe Acrobat PDF | View Details Download |