Barriers to picking and packing in pharmaceutical warehousing and distribution in South Africa
- Authors: Kemp, Nicholas
- Date: 2018
- Subjects: Pharmaceutical industry -- Materials management , Warehouses -- Management Pharmaceutical industry -- South Africa Physical distribution of goods -- Management
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/30627 , vital:30994
- Description: Barriers within the supply chain play an evident role in decreasing its efficiency. The supply chain system is not well documented in the pharmaceutical sector. The aim of this study was to identify any barriers to the movement of picking and packing operators within 6 distribution facilities throughout South Africa using a time and motion analysis. A pilot study was initially conducted to choose the stopwatch application for Android® devices and to ensure reliability of the tools utilised. The motions during the processes of fulfilling an order were identified during the case picking, bulk picking and packing processes by direct observation of operators. The direct observation was performed using a stopwatch application for Android® devices and a tool on Microsoft Excel®. The data was analysed using Microsoft Excel®, using a student’s T-test and an analysis of variance (ANOVA) approach to identify similarities and differences between the facilities. The data was further analysed using a descriptive statistics approach to identify the common barriers amongst the distribution centres. Thereafter, the data was analysed by identifying a value-quotient. The value-quotient was used to identify how much time was spent on value-adding activities with each facility. The observation of the operators was done randomly at each facility to avoid subjectivity and bias. Results: The pilot study identified which stopwatch application was to be utilised. The pilot study aided to improve upon the design of the data collection tool used for the transcribing of the timing operation. The student’s T-test and ANOVA revealed that there were statistically significant differences in case picking amongst facilities, namely using the radio frequency identification devices (RFID), picking and transfer of stock. In the bulk picking process, there was a statistically significant difference amongst the facilities, namely using the RFID, pick and transfer of stock. In the packing process there was a statistically significant difference amongst the facilities in the packing process. The analysis of barriers within the distribution centres revealed that the 16 common barriers amongst the picking processes at the facilities included raising the platform, waiting for colleagues to depart an aisle, RFID malfunctions and answering their phones. No common barriers during the packing process was identified. The value-quotient revealed that most of the facilities spent more than 50 percent of their time on value-adding activities during the case picking, bulk picking and packing processes. A time and motion analysis proved to be an effective method to identify similarities and barriers between the six facilities. It was recommended to investigate a few of the basic operations to improve upon, as well as the possibility of implementing a barcoded system to the stock.
- Full Text:
- Date Issued: 2018
- Authors: Kemp, Nicholas
- Date: 2018
- Subjects: Pharmaceutical industry -- Materials management , Warehouses -- Management Pharmaceutical industry -- South Africa Physical distribution of goods -- Management
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/30627 , vital:30994
- Description: Barriers within the supply chain play an evident role in decreasing its efficiency. The supply chain system is not well documented in the pharmaceutical sector. The aim of this study was to identify any barriers to the movement of picking and packing operators within 6 distribution facilities throughout South Africa using a time and motion analysis. A pilot study was initially conducted to choose the stopwatch application for Android® devices and to ensure reliability of the tools utilised. The motions during the processes of fulfilling an order were identified during the case picking, bulk picking and packing processes by direct observation of operators. The direct observation was performed using a stopwatch application for Android® devices and a tool on Microsoft Excel®. The data was analysed using Microsoft Excel®, using a student’s T-test and an analysis of variance (ANOVA) approach to identify similarities and differences between the facilities. The data was further analysed using a descriptive statistics approach to identify the common barriers amongst the distribution centres. Thereafter, the data was analysed by identifying a value-quotient. The value-quotient was used to identify how much time was spent on value-adding activities with each facility. The observation of the operators was done randomly at each facility to avoid subjectivity and bias. Results: The pilot study identified which stopwatch application was to be utilised. The pilot study aided to improve upon the design of the data collection tool used for the transcribing of the timing operation. The student’s T-test and ANOVA revealed that there were statistically significant differences in case picking amongst facilities, namely using the radio frequency identification devices (RFID), picking and transfer of stock. In the bulk picking process, there was a statistically significant difference amongst the facilities, namely using the RFID, pick and transfer of stock. In the packing process there was a statistically significant difference amongst the facilities in the packing process. The analysis of barriers within the distribution centres revealed that the 16 common barriers amongst the picking processes at the facilities included raising the platform, waiting for colleagues to depart an aisle, RFID malfunctions and answering their phones. No common barriers during the packing process was identified. The value-quotient revealed that most of the facilities spent more than 50 percent of their time on value-adding activities during the case picking, bulk picking and packing processes. A time and motion analysis proved to be an effective method to identify similarities and barriers between the six facilities. It was recommended to investigate a few of the basic operations to improve upon, as well as the possibility of implementing a barcoded system to the stock.
- Full Text:
- Date Issued: 2018
Synthesis, characterization and photophysical studies of RU(II)bipyridyl-dithiocarbamate complexes as sensitizers for dye sensitized solar cells
- Authors: Fudo, Zintle
- Date: 2018
- Subjects: Dye-sensitized solar cells Renewable energy sources
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/6168 , vital:29498
- Description: The depletion of fossil fuels and the increasing energy demand for energy has led to the search for better and improved technologies with special focus renewable energy, especially solar cells. The first generation solar cells based on silicon are expensive, hence dye sensitized solar cells come in as a better alternative as these solar cells are environmental friendly, they have moderately good conversion efficiency and they are relatively cheap to produce. Dithiocarbamate ligands have been widely used in many research fields, as these are versatile ligands. Coordination of dithiocarbamates with metals such as ruthenium has produced high conversion efficiency and have the ability to extend the MLCT absorptions, and this can further extend their wavelength. In this study five dithiocarbamate sodium salt ligands were prepared and were coded as FL1= Aniline, FL2= p- toluidine, FL3= p- anisidine, FL4=dibenzyl, FL5=diphenyl. These ligands were used to synthesize Ru(II) metal complexes which were formulated as [Ru(FLx)(dcbpy)(NCS)] and [Ru(FLx)2(dcbpy)] where FLx is the dithiocarbamate ligand and dcbpy is 2,2-bipyridine-4,4’-dicarboxylic acid and the complexes were coded as FCx. The synthesized compounds were characterized using techniques such as the melting point, molar conductivity, FT-IR and NMR spectroscopy. For spectroelectrochemical studies of the metal complexes, techniques such as UV-Vis and photoluminescence spectroscopy were carried out. Furthermore, redox properties of the complexes were analyzed using cyclic and square wave voltammetry. The FT-IR displayed all the expected peaks of interest both in the dithiocarbamate ligands and in the metal complexes. The electronic spectra confirmed the successful coordination of ligand to the metal centre, the electronic spectra of the complexes also confirmed the six coordinate octahedral geometry of the complexes. The complexes exhibited some photoluminescence properties that are suitable for dye sensitization. The cyclic voltammogram of the complexes displayed more reduction potentials that could be attributed to the π-conjugation in the ligands incorporated during synthesis. The square wave voltammogram of the complexes is in agreement with the results obtained in cyclic voltammetry.
- Full Text:
- Date Issued: 2018
- Authors: Fudo, Zintle
- Date: 2018
- Subjects: Dye-sensitized solar cells Renewable energy sources
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/6168 , vital:29498
- Description: The depletion of fossil fuels and the increasing energy demand for energy has led to the search for better and improved technologies with special focus renewable energy, especially solar cells. The first generation solar cells based on silicon are expensive, hence dye sensitized solar cells come in as a better alternative as these solar cells are environmental friendly, they have moderately good conversion efficiency and they are relatively cheap to produce. Dithiocarbamate ligands have been widely used in many research fields, as these are versatile ligands. Coordination of dithiocarbamates with metals such as ruthenium has produced high conversion efficiency and have the ability to extend the MLCT absorptions, and this can further extend their wavelength. In this study five dithiocarbamate sodium salt ligands were prepared and were coded as FL1= Aniline, FL2= p- toluidine, FL3= p- anisidine, FL4=dibenzyl, FL5=diphenyl. These ligands were used to synthesize Ru(II) metal complexes which were formulated as [Ru(FLx)(dcbpy)(NCS)] and [Ru(FLx)2(dcbpy)] where FLx is the dithiocarbamate ligand and dcbpy is 2,2-bipyridine-4,4’-dicarboxylic acid and the complexes were coded as FCx. The synthesized compounds were characterized using techniques such as the melting point, molar conductivity, FT-IR and NMR spectroscopy. For spectroelectrochemical studies of the metal complexes, techniques such as UV-Vis and photoluminescence spectroscopy were carried out. Furthermore, redox properties of the complexes were analyzed using cyclic and square wave voltammetry. The FT-IR displayed all the expected peaks of interest both in the dithiocarbamate ligands and in the metal complexes. The electronic spectra confirmed the successful coordination of ligand to the metal centre, the electronic spectra of the complexes also confirmed the six coordinate octahedral geometry of the complexes. The complexes exhibited some photoluminescence properties that are suitable for dye sensitization. The cyclic voltammogram of the complexes displayed more reduction potentials that could be attributed to the π-conjugation in the ligands incorporated during synthesis. The square wave voltammogram of the complexes is in agreement with the results obtained in cyclic voltammetry.
- Full Text:
- Date Issued: 2018
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