Synthesis, characterization and in vitro antibacterial analysis of carvacrol based-hybrid analogues
- Authors: Mbese, Zintle
- Date: 2019
- Subjects: Medicinal plants Herbs -- Therapeutic use
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/14527 , vital:39998
- Description: he focus of this research was to synthesize and characterize carvacrol hybrid analogues. Twenty-one (21) carvacrol analogues were synthesized by reacting carvacrol with (1. 4- aminosalicylic acid, 2. ferrocene keto-butanoic acid, 3. Ferrocene butanoic acid, 4. succinic anhydride, 5. folic acid, 6. cinnamic acid, 7. leucovorin, 8. oleanolic acid, 9. artesunate, 10. cholesterol, 11. cholesterol succinate, 12. curcumin, 13. curcumin succinate, 14. zidovudine, 15. Zidovudine succinate, 16. 8-hydroxyquinoline, 17. 8-hydroxyquinoline succinate, 18. 2- (7-chloroquinolin-4-ylamino)ethyl 5-isopropyl-2-methylphenyl, 19. 2-(7-chloroquinolin-4- ylamino)ethyl 5-isopropyl-2-methylphenyl succinate, 20. 2-(2-(7-chloroquinolin-4- ylamino)ethoxy)ethyl 5-isopropyl-2-methylphenyl, 21. 2-(2-(7-chloroquinolin-4- ylamino)ethoxy)ethyl 5-isopropyl-2-methylphenyl succinate). The carvacrol analogues were characterized using FTIR, UHPLC-HRMS, 1H- and 13C-NMR spectroscopy. The antibacterial analysis was performed to evaluate the carvacrol analogues against bacterial strains. FTIR spectra of carvacrol analogues were found to exhibit peaks of C-O stretch and Ar-C in a range of 1014-1280 cm-1 and a range of 1414-1697 cm-1 which confirm the successful formation of esters. The proposed structures of carvacrol analogues were confirmed by the 1H- and 13C-NMR. The selected 1H-NMR signal for aromatic protons ranged at 6.00-8.95 ppm/δ. The selected 13C-NMR signal for ester carbon and aromatic carbons ranged at 160.0-175.0 ppm/δ and at 110.00-154.00 ppm/δ. The structures were also confirmed by UHPLC-HRMS. Carvacrol analogues exhibited the highest inhibitory effect against Gram-positive and Gram-negative tested bacterial strains.
- Full Text:
- Date Issued: 2019
- Authors: Mbese, Zintle
- Date: 2019
- Subjects: Medicinal plants Herbs -- Therapeutic use
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/14527 , vital:39998
- Description: he focus of this research was to synthesize and characterize carvacrol hybrid analogues. Twenty-one (21) carvacrol analogues were synthesized by reacting carvacrol with (1. 4- aminosalicylic acid, 2. ferrocene keto-butanoic acid, 3. Ferrocene butanoic acid, 4. succinic anhydride, 5. folic acid, 6. cinnamic acid, 7. leucovorin, 8. oleanolic acid, 9. artesunate, 10. cholesterol, 11. cholesterol succinate, 12. curcumin, 13. curcumin succinate, 14. zidovudine, 15. Zidovudine succinate, 16. 8-hydroxyquinoline, 17. 8-hydroxyquinoline succinate, 18. 2- (7-chloroquinolin-4-ylamino)ethyl 5-isopropyl-2-methylphenyl, 19. 2-(7-chloroquinolin-4- ylamino)ethyl 5-isopropyl-2-methylphenyl succinate, 20. 2-(2-(7-chloroquinolin-4- ylamino)ethoxy)ethyl 5-isopropyl-2-methylphenyl, 21. 2-(2-(7-chloroquinolin-4- ylamino)ethoxy)ethyl 5-isopropyl-2-methylphenyl succinate). The carvacrol analogues were characterized using FTIR, UHPLC-HRMS, 1H- and 13C-NMR spectroscopy. The antibacterial analysis was performed to evaluate the carvacrol analogues against bacterial strains. FTIR spectra of carvacrol analogues were found to exhibit peaks of C-O stretch and Ar-C in a range of 1014-1280 cm-1 and a range of 1414-1697 cm-1 which confirm the successful formation of esters. The proposed structures of carvacrol analogues were confirmed by the 1H- and 13C-NMR. The selected 1H-NMR signal for aromatic protons ranged at 6.00-8.95 ppm/δ. The selected 13C-NMR signal for ester carbon and aromatic carbons ranged at 160.0-175.0 ppm/δ and at 110.00-154.00 ppm/δ. The structures were also confirmed by UHPLC-HRMS. Carvacrol analogues exhibited the highest inhibitory effect against Gram-positive and Gram-negative tested bacterial strains.
- Full Text:
- Date Issued: 2019
The sustainability of international labour organisation’s youth empowerment programme in Harare
- Authors: Muradya, Thelma Irene
- Date: 2019
- Subjects: Youth in development -- Zimbabwe -- Harare , Youth -- Employment -- Zimbabwe -- Harare , Community development -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/41592 , vital:36543
- Description: The study evaluated the sustainability of the International Labour Organisation’s ‘Skills for youth employment and rural development’ programme in Harare. The purpose of the study was to understand the reasons behind the rise of youth unemployment despite many interventions targeting youth being implemented within the country. Youth contribute to the development of nations if presented with opportunities. Also, the economy of Zimbabwe is highly informal; hence the need to assess the long term impact made by strengthening the skills of the youth through informal apprenticeships and if there were possibilities of growth within their businesses. Sustainability issues were therefore critical in addressing problems faced by youth empowerment initiatives, so as to ensure that beneficiaries of programs attain long term benefits in future and that future programmes can also make sustainability their core focus. This mixed method study utilised interviews with youth beneficiaries and an ILO official in Harare as well as document analysis to gather data about the programme. The findings indicated that despite the programme achieving its targeted objectives and providing skills within the various sectors as well as business and leadership skills, majority of youth remain unemployed. This is mostly attributed to a lack of financial support to start or grow businesses, politicisation of programmes and the unstable state of the Zimbabwean economy which is not favourable for the survival and growth of small businesses. The researcher recommended increased government participation and collaboration with the private sector to promote youth businesses and tackle unemployment in a holistic manner. Promotion of economic growth and stability, depolitising empowerment programmes and strengthening monitoring and evaluation systems are also crucial to achieve real impact in youth development initiatives. Furthermore, providing financial support, will aid in starting and sustaining businesses, after training.
- Full Text:
- Date Issued: 2019
- Authors: Muradya, Thelma Irene
- Date: 2019
- Subjects: Youth in development -- Zimbabwe -- Harare , Youth -- Employment -- Zimbabwe -- Harare , Community development -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/41592 , vital:36543
- Description: The study evaluated the sustainability of the International Labour Organisation’s ‘Skills for youth employment and rural development’ programme in Harare. The purpose of the study was to understand the reasons behind the rise of youth unemployment despite many interventions targeting youth being implemented within the country. Youth contribute to the development of nations if presented with opportunities. Also, the economy of Zimbabwe is highly informal; hence the need to assess the long term impact made by strengthening the skills of the youth through informal apprenticeships and if there were possibilities of growth within their businesses. Sustainability issues were therefore critical in addressing problems faced by youth empowerment initiatives, so as to ensure that beneficiaries of programs attain long term benefits in future and that future programmes can also make sustainability their core focus. This mixed method study utilised interviews with youth beneficiaries and an ILO official in Harare as well as document analysis to gather data about the programme. The findings indicated that despite the programme achieving its targeted objectives and providing skills within the various sectors as well as business and leadership skills, majority of youth remain unemployed. This is mostly attributed to a lack of financial support to start or grow businesses, politicisation of programmes and the unstable state of the Zimbabwean economy which is not favourable for the survival and growth of small businesses. The researcher recommended increased government participation and collaboration with the private sector to promote youth businesses and tackle unemployment in a holistic manner. Promotion of economic growth and stability, depolitising empowerment programmes and strengthening monitoring and evaluation systems are also crucial to achieve real impact in youth development initiatives. Furthermore, providing financial support, will aid in starting and sustaining businesses, after training.
- Full Text:
- Date Issued: 2019
Exhaustible resources and the hotelling rule : an empirical test of the hotelling rule's significance to gold production in South Africa
- Authors: Mlambo, Courage
- Date: 2017
- Subjects: Natural resources -- Mathematical models Econometrics
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/4738 , vital:28507
- Description: The study sought to test the applicability of the Hotelling rule in South Africa. In environmental economics, the Hotelling rule has come to be a pillar of the exhaustible resources framework and in addition to this, it has presented essential insights into the consumption and extraction of non-renewable resources. Hotelling sought to address one important question which had been unanswered regarding the depletion of exhaustible resources: How much of the natural resource in question should be consumed presently and how much of it should be stocked up for future generations? The focus was to find a solution for those involved in the exploitation of natural resources to choose between the current value of the natural resource if extracted and sold and the future increased value of the asset if left unexploited. According to the Hotelling rule, the extraction path in competitive market economies will, under certain circumstances, be socially optimal. An extraction path that is not socially optimal compromises the welfare of future generations. The welfare of South Africa’s present population and more especially in the future will be greatly determined by the stock of natural resources available and the quality of the environment. Currently, the production processes deplete natural resources. Concern with the supposed increasing scarcity of gold in South Africa, and the possibility of running out of gold, has become a source of concern. South Africa’s gold reserves (gold in the ground that can be extracted profitably) are becoming depleted at an alarming rate. Most reserves are already exhausted; and the costs involved in mining lower-grade ore, and deposits located very deep in the ground, are becoming excessive. In light of this, this study sought to test the applicability of the Hotelling rule in South Africa. In order to empirically test the Hotelling rule, the study was guided by previous literature that had sought to test it. In this regard, the study used both descriptive and inferential statistics. The study has three data analysis chapters. The first two presented and examined the time series properties of gold prices, gold production and gold consumption. The third data analysis chapter examined the relationship between gold price and interest rates. In the first two data analysis chapters, visual inspection, growth rates, variance ratio tests and advanced unit root tests were used to examine the time series properties of gold prices, gold production and gold consumption. Results showed that the behaviour of the gold price series and gold production series in South Africa have a behaviour that is socially optimal. This is in line with the Hotelling rule. The rule predicts exponentially increasing resource prices and this result in mineral resources following the path of the positive trend. The positive trend is prompted by the increasing price reflecting the increasing scarcity of the resource. However, consumption trends were seen to be violating the Hotelling rule. The Hotelling rule predicts that the price increases until it eventually reaches the choke price, where the quantity demanded decreases to zero. However, in contrast to this, results showed that the demand for gold has been increasing instead of decreasing. This is not in line with the Hotelling rule. Furthermore the relationship between interest rate and gold price was negative and this suggested that the price of gold was not rising at the rate of the interest rate. The results of the study suggested that gold production is not following a social optimally path. The study recommended that the government come up with measures that prolong the lifespan of the gold reserves. These included research and development to promote technological innovations in the mining sector. This may make it possible for firms to access lower-grade ores. The study also recommended that since the Hotelling rule partly applied in the gold sector, there is a need to adopt some other theoretical measures that can ensure that the proceeds from the gold taxes are used in the most effective way.
- Full Text:
- Date Issued: 2017
- Authors: Mlambo, Courage
- Date: 2017
- Subjects: Natural resources -- Mathematical models Econometrics
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/4738 , vital:28507
- Description: The study sought to test the applicability of the Hotelling rule in South Africa. In environmental economics, the Hotelling rule has come to be a pillar of the exhaustible resources framework and in addition to this, it has presented essential insights into the consumption and extraction of non-renewable resources. Hotelling sought to address one important question which had been unanswered regarding the depletion of exhaustible resources: How much of the natural resource in question should be consumed presently and how much of it should be stocked up for future generations? The focus was to find a solution for those involved in the exploitation of natural resources to choose between the current value of the natural resource if extracted and sold and the future increased value of the asset if left unexploited. According to the Hotelling rule, the extraction path in competitive market economies will, under certain circumstances, be socially optimal. An extraction path that is not socially optimal compromises the welfare of future generations. The welfare of South Africa’s present population and more especially in the future will be greatly determined by the stock of natural resources available and the quality of the environment. Currently, the production processes deplete natural resources. Concern with the supposed increasing scarcity of gold in South Africa, and the possibility of running out of gold, has become a source of concern. South Africa’s gold reserves (gold in the ground that can be extracted profitably) are becoming depleted at an alarming rate. Most reserves are already exhausted; and the costs involved in mining lower-grade ore, and deposits located very deep in the ground, are becoming excessive. In light of this, this study sought to test the applicability of the Hotelling rule in South Africa. In order to empirically test the Hotelling rule, the study was guided by previous literature that had sought to test it. In this regard, the study used both descriptive and inferential statistics. The study has three data analysis chapters. The first two presented and examined the time series properties of gold prices, gold production and gold consumption. The third data analysis chapter examined the relationship between gold price and interest rates. In the first two data analysis chapters, visual inspection, growth rates, variance ratio tests and advanced unit root tests were used to examine the time series properties of gold prices, gold production and gold consumption. Results showed that the behaviour of the gold price series and gold production series in South Africa have a behaviour that is socially optimal. This is in line with the Hotelling rule. The rule predicts exponentially increasing resource prices and this result in mineral resources following the path of the positive trend. The positive trend is prompted by the increasing price reflecting the increasing scarcity of the resource. However, consumption trends were seen to be violating the Hotelling rule. The Hotelling rule predicts that the price increases until it eventually reaches the choke price, where the quantity demanded decreases to zero. However, in contrast to this, results showed that the demand for gold has been increasing instead of decreasing. This is not in line with the Hotelling rule. Furthermore the relationship between interest rate and gold price was negative and this suggested that the price of gold was not rising at the rate of the interest rate. The results of the study suggested that gold production is not following a social optimally path. The study recommended that the government come up with measures that prolong the lifespan of the gold reserves. These included research and development to promote technological innovations in the mining sector. This may make it possible for firms to access lower-grade ores. The study also recommended that since the Hotelling rule partly applied in the gold sector, there is a need to adopt some other theoretical measures that can ensure that the proceeds from the gold taxes are used in the most effective way.
- Full Text:
- Date Issued: 2017
Impediments to the implementation of employee health and wellness policy : a study of Social Development - Eastern Cape, Amathole District
- Authors: Lutuli, Nondwe
- Date: 2017
- Subjects: Employee health promotion -- South Africa -- Eastern Cape Employee motivation -- South Africa -- Eastern Cape Health education|xGovernment policy -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSoc
- Identifier: http://hdl.handle.net/10353/5473 , vital:29269
- Description: The White paper on Transforming Public Service Delivery no 1459 of 1997 stipulates that the wellbeing of employees needs to be accounted for. A directive to have employee health and wellness programmes established in all government departments was given by the director-general of the Department Public Service Administration in 2008. The Employee health and wellness programme is aimed at promoting and improving employee wellbeing, which is also linked to organizational wellness. The primary aim of the Employee Assistance Programme (EAP) is to make a positive contribution towards maximum employee productivity and effectiveness in the workplace. Employee health assessment conducted by the Department of Social Development in 2006 and 2009 confirmed that South African organizations, including the Department of Social Development, experience high levels of employee poor health. Studies suggest that both employees and the employers need to pay attention to the improvement of employee health and wellness. In 2012, an integrated employee health and wellness policy was developed to improve the Department of Social Development employee wellness. The interest to conduct the study emanates from the researcher‟s own supposition that the policy has not been fully implemented, this deduction is based on the fact that, although the policy has four critical focus areas, some of these areas, such as counselling, are not rendered. Literature reviewed includes the process of policy implementation and description of employee health and wellness, benefits of employee health and wellness programme for both employees and employer. A mixed method study was conducted to explore the implementation of the employee health and wellness policy as a strategy to improve both employee and organizational wellness within the Department of Social Development, Eastern Cape - Amathole District. The population of the study included both DSD management and non-managerial employees from Amathole District; the study also includes the Eastern Cape Department of Transport, Amathole District Municipality and South African Police Service (Mdantsane). Themes that were identified from qualitative data through semi- structured interviews by means of audio-recorder were triangulated through questionnaires and document analysis. Since the policy came into effect in 2012, results show that the implementation has been confronted with a number of challenges which include lack of support from the top management. Lack of buy in by DSD management has serious implications on the policy objectives; these include the inadequate distribution of capital, human and physical resources necessary to implement the policy. In order for the DSD to improve the implementation of employee health and wellness policy, the management needs to ensure that there is adequate provision of human and capital resources. Employees should be well-informed on policy guidelines and procedures and benefits to stimulate maximum utilisation. A decentralisation of implementation to Area offices is necessary to promote accessibility of services and prevent unnecessary delays in service delivery.
- Full Text:
- Date Issued: 2017
- Authors: Lutuli, Nondwe
- Date: 2017
- Subjects: Employee health promotion -- South Africa -- Eastern Cape Employee motivation -- South Africa -- Eastern Cape Health education|xGovernment policy -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSoc
- Identifier: http://hdl.handle.net/10353/5473 , vital:29269
- Description: The White paper on Transforming Public Service Delivery no 1459 of 1997 stipulates that the wellbeing of employees needs to be accounted for. A directive to have employee health and wellness programmes established in all government departments was given by the director-general of the Department Public Service Administration in 2008. The Employee health and wellness programme is aimed at promoting and improving employee wellbeing, which is also linked to organizational wellness. The primary aim of the Employee Assistance Programme (EAP) is to make a positive contribution towards maximum employee productivity and effectiveness in the workplace. Employee health assessment conducted by the Department of Social Development in 2006 and 2009 confirmed that South African organizations, including the Department of Social Development, experience high levels of employee poor health. Studies suggest that both employees and the employers need to pay attention to the improvement of employee health and wellness. In 2012, an integrated employee health and wellness policy was developed to improve the Department of Social Development employee wellness. The interest to conduct the study emanates from the researcher‟s own supposition that the policy has not been fully implemented, this deduction is based on the fact that, although the policy has four critical focus areas, some of these areas, such as counselling, are not rendered. Literature reviewed includes the process of policy implementation and description of employee health and wellness, benefits of employee health and wellness programme for both employees and employer. A mixed method study was conducted to explore the implementation of the employee health and wellness policy as a strategy to improve both employee and organizational wellness within the Department of Social Development, Eastern Cape - Amathole District. The population of the study included both DSD management and non-managerial employees from Amathole District; the study also includes the Eastern Cape Department of Transport, Amathole District Municipality and South African Police Service (Mdantsane). Themes that were identified from qualitative data through semi- structured interviews by means of audio-recorder were triangulated through questionnaires and document analysis. Since the policy came into effect in 2012, results show that the implementation has been confronted with a number of challenges which include lack of support from the top management. Lack of buy in by DSD management has serious implications on the policy objectives; these include the inadequate distribution of capital, human and physical resources necessary to implement the policy. In order for the DSD to improve the implementation of employee health and wellness policy, the management needs to ensure that there is adequate provision of human and capital resources. Employees should be well-informed on policy guidelines and procedures and benefits to stimulate maximum utilisation. A decentralisation of implementation to Area offices is necessary to promote accessibility of services and prevent unnecessary delays in service delivery.
- Full Text:
- Date Issued: 2017
Prevalence of Group B streptococcus and staphylococcus aureus colonization in the anogenital tract of pregnant women in the Eastern Cape Province, South Africa
- Authors: Stofile, P Z
- Date: 2017
- Subjects: Streptococcal infections Staphylococcus aureus
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/5983 , vital:29462
- Description: Neonatal sickness and death is increasingly becoming a public health problem worldwide. The colonization of Group B Streptococcus and Staphylococcus in the rectovaginal area is among the sources of infections in neonates which can result in illness and mortality. The over exposure of humans to antibiotics is the possible cause of resistance in bacteria. These resistant strains can be passed onto offspring, leading to resistant infections and increasing the morbidity of neonates because of treatment failures. Many people, including healthcare personnel are not aware of the effect of these bacteria, and informing clinics and hospitals can help create awareness and monitoring the levels of resistance among bacteria can assist in preventing the transference of the bacteria. In this study we investigated the prevalence of group B Streptococcus (GBS) and Staphylococcus aureus in the anogenital tract of pregnant women in the Eastern Cape Province, South Africa. A total of 49 isolates from 25 (30.5 percent) pregnant women colonized with GBS were isolated from vaginal and rectal swabs of 82 pregnant women at 25-37 gestation who participated in this study. These isolates were obtained using standard microbiological methods and confirmed by polymerase chain reaction (PCR) technique aimed at the ScpB gene. The isolates were further screened for the presence of 9 serogroups (Ia, Ib, II, III, IV, V, VI, VII, VII) and serogroups Ib 2 (4.8 percent), II 20 (40.8 percent) and IV 5 (10.2 percent) and 22 non-typable (44.9 percent) were identified. Susceptibility profiling of the isolates to 12 antibiotics (tetracycline, clindamycin, erythromycin, gentamycin, naladixic acid, norfloxacin, chloramphenicol, cefuroxime, cefotaxime, imipenem, penicillin and vancomycin) was tested in vitro by the standardized disc diffusion method. All the confirmed GBS isolates (49) were resistant to erythromycin, tetracycline and clindamycin. A higher percentage of the isolates were resistant to gentamycin 44 (90 percent), nalidixic acid 41 (84 percent), penicillin 41 (84 percent), chloramphenicol 38 (78 percent), cefuroxime 36 (74 percent), imipenem 36 (74 percent), cefotaxime 35 (71 percent), norfloxacin 32 (65 percent) and vancomycin 31 (78 percent). Multiple antimicrobial resistance patterns ranged from 9‒11 and indices ranged from 0.7‒0.9, respectively. Among the antimicrobial resistance determinants examined, genes encoding for resistance to erythromycin ermB 25 (51 percent), tetracycline tetM 32 (65 percent) and penicillin bla-Z 4 (8 percent) only were identified. On the other hand, screening for S. aureus yielded a total of 7 isolates from 4 study participants as confirmed by PCR based on staphylococcal, nuc gene. The isolates were further screened for the presence of six virulence genes (Hla, Hlb, LUKM, LUKED, PVL, Eta and Etb) and antibiotic susceptibility pattern by the disc diffusion method using 12 (penicillin, vancomycin, tetracycline, rifampicin, imipenem, gentamycin, chloramphenicol, norfloxacin, oxacillin, erythromycin and sulfamethoxazole-trimethoprim) antibiotics that are adopted in the treatment of infections caused by the organism. PVL 6 (85.7 percent) and eta 1 (14.3 percent) were the two virulence genes detected. The following percentages of antibiotics resistance among the isolates were observed; penicillin G 7 (100 percent), clindamycin 7 (100 percent), vancomycin 5 (100 percent), rifampicin 5 (71 percent), oxacillin 5 (71 percent), erythromycin 5 (71 percent) gentamycin 3 (43 percent), norfloxacin 3 (43 percent), sulfamethoxazole-trimethoprim 3 (43 percent), chloramphenicol 2 (29 percent), imipenem 1 (14 percent). Multiple antimicrobial resistance patterns ranged from 7‒8 and indices ranged from 0.6‒0.7, respectively. Genetic profiling of the resistance genes identified erythromycin ermB 5(71.4 percent), tetracycline tetM 5(71.4 percent) and penicillin bla-Z 1(14.3 percent) only. The findings from the study have revealed GBS and S. aureus colonization of pregnant women in the Eastern Cape Province, and these have great public health implications especially for the neonates who are mostly likely to be infected during birth. The unidentifiable multidrug resistant serogroups of GBS as well as resistant S. aureus limit the choice of drugs in the management of infections caused by these pathogens more so if transmitted to infants. Therefore asymptomatic pregnant women needed to be properly educated about the bacteria as well as the precautions that need to be taken.
- Full Text:
- Date Issued: 2017
- Authors: Stofile, P Z
- Date: 2017
- Subjects: Streptococcal infections Staphylococcus aureus
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/5983 , vital:29462
- Description: Neonatal sickness and death is increasingly becoming a public health problem worldwide. The colonization of Group B Streptococcus and Staphylococcus in the rectovaginal area is among the sources of infections in neonates which can result in illness and mortality. The over exposure of humans to antibiotics is the possible cause of resistance in bacteria. These resistant strains can be passed onto offspring, leading to resistant infections and increasing the morbidity of neonates because of treatment failures. Many people, including healthcare personnel are not aware of the effect of these bacteria, and informing clinics and hospitals can help create awareness and monitoring the levels of resistance among bacteria can assist in preventing the transference of the bacteria. In this study we investigated the prevalence of group B Streptococcus (GBS) and Staphylococcus aureus in the anogenital tract of pregnant women in the Eastern Cape Province, South Africa. A total of 49 isolates from 25 (30.5 percent) pregnant women colonized with GBS were isolated from vaginal and rectal swabs of 82 pregnant women at 25-37 gestation who participated in this study. These isolates were obtained using standard microbiological methods and confirmed by polymerase chain reaction (PCR) technique aimed at the ScpB gene. The isolates were further screened for the presence of 9 serogroups (Ia, Ib, II, III, IV, V, VI, VII, VII) and serogroups Ib 2 (4.8 percent), II 20 (40.8 percent) and IV 5 (10.2 percent) and 22 non-typable (44.9 percent) were identified. Susceptibility profiling of the isolates to 12 antibiotics (tetracycline, clindamycin, erythromycin, gentamycin, naladixic acid, norfloxacin, chloramphenicol, cefuroxime, cefotaxime, imipenem, penicillin and vancomycin) was tested in vitro by the standardized disc diffusion method. All the confirmed GBS isolates (49) were resistant to erythromycin, tetracycline and clindamycin. A higher percentage of the isolates were resistant to gentamycin 44 (90 percent), nalidixic acid 41 (84 percent), penicillin 41 (84 percent), chloramphenicol 38 (78 percent), cefuroxime 36 (74 percent), imipenem 36 (74 percent), cefotaxime 35 (71 percent), norfloxacin 32 (65 percent) and vancomycin 31 (78 percent). Multiple antimicrobial resistance patterns ranged from 9‒11 and indices ranged from 0.7‒0.9, respectively. Among the antimicrobial resistance determinants examined, genes encoding for resistance to erythromycin ermB 25 (51 percent), tetracycline tetM 32 (65 percent) and penicillin bla-Z 4 (8 percent) only were identified. On the other hand, screening for S. aureus yielded a total of 7 isolates from 4 study participants as confirmed by PCR based on staphylococcal, nuc gene. The isolates were further screened for the presence of six virulence genes (Hla, Hlb, LUKM, LUKED, PVL, Eta and Etb) and antibiotic susceptibility pattern by the disc diffusion method using 12 (penicillin, vancomycin, tetracycline, rifampicin, imipenem, gentamycin, chloramphenicol, norfloxacin, oxacillin, erythromycin and sulfamethoxazole-trimethoprim) antibiotics that are adopted in the treatment of infections caused by the organism. PVL 6 (85.7 percent) and eta 1 (14.3 percent) were the two virulence genes detected. The following percentages of antibiotics resistance among the isolates were observed; penicillin G 7 (100 percent), clindamycin 7 (100 percent), vancomycin 5 (100 percent), rifampicin 5 (71 percent), oxacillin 5 (71 percent), erythromycin 5 (71 percent) gentamycin 3 (43 percent), norfloxacin 3 (43 percent), sulfamethoxazole-trimethoprim 3 (43 percent), chloramphenicol 2 (29 percent), imipenem 1 (14 percent). Multiple antimicrobial resistance patterns ranged from 7‒8 and indices ranged from 0.6‒0.7, respectively. Genetic profiling of the resistance genes identified erythromycin ermB 5(71.4 percent), tetracycline tetM 5(71.4 percent) and penicillin bla-Z 1(14.3 percent) only. The findings from the study have revealed GBS and S. aureus colonization of pregnant women in the Eastern Cape Province, and these have great public health implications especially for the neonates who are mostly likely to be infected during birth. The unidentifiable multidrug resistant serogroups of GBS as well as resistant S. aureus limit the choice of drugs in the management of infections caused by these pathogens more so if transmitted to infants. Therefore asymptomatic pregnant women needed to be properly educated about the bacteria as well as the precautions that need to be taken.
- Full Text:
- Date Issued: 2017
Quality indices of the Nahoon beach and canal in Buffalo City Metropolitan Municipality, Eastern Cape, South Africa
- Authors: Ebomah, Kingsley Ehi
- Date: 2017
- Subjects: Pathogenic bacteria -- South Africa -- Eastern Cape Water quality -- South Africa -- Eastern Cape -- Measurement Water -- Microbiology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/8122 , vital:31525
- Description: Faecal indicator bacteria have long been recommended for usage in water quality monitoring of various water sources including surface water. A large number of people in different parts of the world often engage in recreational and other commercial activities at the various beaches along the coastal lines, most especially, during summer season and festive periods. It is generally assumed that beach water is safe all the times, however, there have been increasing reports of beach and other coastal water pollutions because of rising anthropogenic activities around coastal areas globally. The presence of pathogens in faecal contaminated beach water either directly or indirectly increases the risk of human exposure which may result in skin infections as well as the ingestion and transmission of multidrug resistant pathogens. Microorganisms may gain entry into beach water directly from improperly treated final effluents released by wastewater treatment plants and from agricultural runoffs and/or faulty drainages. The aim of this study was to evaluate the quality indices of the Nahoon Beach and canal waters in the Eastern Cape Province of South Africa. In order to achieve this aim, the objectives of this study were as follow: to determine the seasonal variations of the physicochemical characteristics of the Nahoon beach and canal waters, to assess the microbiological quality of the beach water by assessing the prevalence of potentially E. coli and Enterococcus species, and to evaluate the antibiogram profile of the E. coli pathotypes and Enterococci species recovered from the beach water samples. Water samples were collected bi-weekly for a period of twelve months, during which on-site physicochemical analyses were carried out. Bacteriological assessment was performed using the membrane filtration technique and the necessary incubation conditions were followed. Identification of the target organisms was done by molecular based methods using PCR (polymerase chain reaction) while antibiotic susceptibility testing was done using the disk diffusion method. During the spring season (August to October) and periods of festive activities (December, January and March), it was observed that turbidity was at its highest, consequently, influencing total dissolved solids and a rise in the values of pH and electrical conductivity. Microbiological qualities assessed follow the order: Escherichia coli (101 – 103 CFU/100ml) and Enterococcus (101 – 102 CFU/100 ml). The results show that 41.2percent (107/260) of the presumptive E. coli isolates were positive for uidA gene. A total of 73 out of 107 (68.2percent) PCR-confirmed E. coli isolates were observed to belong to different pathotypes while 59percent (102/172) of the presumptive Enterococcus strains isolated were positive for SodA gene (Enterococcus spp.). Out of 102 enterococci isolates, 45 strains were identified as species (E. faecalis and E. faecium) and these were subjected to antibiotic susceptibility testing. The E. coli strains exhibited a frequency of 100percent resistance against ampicillin while the Enterococcus strains also showed 100percent resistance against vancomycin and linezolid. Target genes eae 11 (10.3percent); ipaH 14 (13.1percent); ibeA 48 (44.9percent) that encode pathogenicity in E. coli were successfully amplified by PCR suggesting that the isolates are potentially pathogenic strains whereas Enterococcus spp. including Enterococcus faecalis 26 (25.5percent) and Enterococcus faecium 19 (18.6percent) were also identified in the water samples. In this study, the phenotypic antibiogram profiles of the E. coli isolates revealed that all 73 (100percent) of the pathotypes were resistant to ampicillin, 67 (91.8percent) were resistant to amikacin, gentamicin and ceftazidime while about 61 (83.6percent) and 51 (69.9percent) were resistant to tetracycline and ciprofloxacin as well as trimethoprim respectively. About 21.9percent (16) of the E. coli isolates exhibited multiple antibiotic resistances with 100percent being resistant to eight antibiotics whereas multiple antimicrobial resistances were observed in 14 (31percent) of the enterococci strains and the most predominant profile was the simultaneous resistance to ampicillin, penicillin and vancomycin. The results obtained in this study show that the beach water generally did not comply with the set guidelines. The results also suggest the possible survival and prevalence of potentially virulent E. coli as well as Enterococcus strains in the aquatic environment which may be a cause of concern for public health. Monitoring of the quality of surface water and antimicrobial resistance (AMR) in bacteria is of great importance and has clinical and human health significance. Nonetheless, this study underscores the need for more detailed study of other waterborne pathogens of health importance including enteric viruses to ascertain the safety of the beach for human use.
- Full Text:
- Date Issued: 2017
- Authors: Ebomah, Kingsley Ehi
- Date: 2017
- Subjects: Pathogenic bacteria -- South Africa -- Eastern Cape Water quality -- South Africa -- Eastern Cape -- Measurement Water -- Microbiology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/8122 , vital:31525
- Description: Faecal indicator bacteria have long been recommended for usage in water quality monitoring of various water sources including surface water. A large number of people in different parts of the world often engage in recreational and other commercial activities at the various beaches along the coastal lines, most especially, during summer season and festive periods. It is generally assumed that beach water is safe all the times, however, there have been increasing reports of beach and other coastal water pollutions because of rising anthropogenic activities around coastal areas globally. The presence of pathogens in faecal contaminated beach water either directly or indirectly increases the risk of human exposure which may result in skin infections as well as the ingestion and transmission of multidrug resistant pathogens. Microorganisms may gain entry into beach water directly from improperly treated final effluents released by wastewater treatment plants and from agricultural runoffs and/or faulty drainages. The aim of this study was to evaluate the quality indices of the Nahoon Beach and canal waters in the Eastern Cape Province of South Africa. In order to achieve this aim, the objectives of this study were as follow: to determine the seasonal variations of the physicochemical characteristics of the Nahoon beach and canal waters, to assess the microbiological quality of the beach water by assessing the prevalence of potentially E. coli and Enterococcus species, and to evaluate the antibiogram profile of the E. coli pathotypes and Enterococci species recovered from the beach water samples. Water samples were collected bi-weekly for a period of twelve months, during which on-site physicochemical analyses were carried out. Bacteriological assessment was performed using the membrane filtration technique and the necessary incubation conditions were followed. Identification of the target organisms was done by molecular based methods using PCR (polymerase chain reaction) while antibiotic susceptibility testing was done using the disk diffusion method. During the spring season (August to October) and periods of festive activities (December, January and March), it was observed that turbidity was at its highest, consequently, influencing total dissolved solids and a rise in the values of pH and electrical conductivity. Microbiological qualities assessed follow the order: Escherichia coli (101 – 103 CFU/100ml) and Enterococcus (101 – 102 CFU/100 ml). The results show that 41.2percent (107/260) of the presumptive E. coli isolates were positive for uidA gene. A total of 73 out of 107 (68.2percent) PCR-confirmed E. coli isolates were observed to belong to different pathotypes while 59percent (102/172) of the presumptive Enterococcus strains isolated were positive for SodA gene (Enterococcus spp.). Out of 102 enterococci isolates, 45 strains were identified as species (E. faecalis and E. faecium) and these were subjected to antibiotic susceptibility testing. The E. coli strains exhibited a frequency of 100percent resistance against ampicillin while the Enterococcus strains also showed 100percent resistance against vancomycin and linezolid. Target genes eae 11 (10.3percent); ipaH 14 (13.1percent); ibeA 48 (44.9percent) that encode pathogenicity in E. coli were successfully amplified by PCR suggesting that the isolates are potentially pathogenic strains whereas Enterococcus spp. including Enterococcus faecalis 26 (25.5percent) and Enterococcus faecium 19 (18.6percent) were also identified in the water samples. In this study, the phenotypic antibiogram profiles of the E. coli isolates revealed that all 73 (100percent) of the pathotypes were resistant to ampicillin, 67 (91.8percent) were resistant to amikacin, gentamicin and ceftazidime while about 61 (83.6percent) and 51 (69.9percent) were resistant to tetracycline and ciprofloxacin as well as trimethoprim respectively. About 21.9percent (16) of the E. coli isolates exhibited multiple antibiotic resistances with 100percent being resistant to eight antibiotics whereas multiple antimicrobial resistances were observed in 14 (31percent) of the enterococci strains and the most predominant profile was the simultaneous resistance to ampicillin, penicillin and vancomycin. The results obtained in this study show that the beach water generally did not comply with the set guidelines. The results also suggest the possible survival and prevalence of potentially virulent E. coli as well as Enterococcus strains in the aquatic environment which may be a cause of concern for public health. Monitoring of the quality of surface water and antimicrobial resistance (AMR) in bacteria is of great importance and has clinical and human health significance. Nonetheless, this study underscores the need for more detailed study of other waterborne pathogens of health importance including enteric viruses to ascertain the safety of the beach for human use.
- Full Text:
- Date Issued: 2017
The effect of different seating conditions, in aircrafts, on passenger comfort and the use of cabin space
- Authors: Olley, Emma-Jane
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/19734 , vital:22479
- Description: Although aircraft cabin design has improved over the years, passengers continue to complain about sitting discomfort whilst flying. These complaints are often centred on the cramped and restricted seating conditions. Whilst passenger comfort is important, in order for airline companies to attract and retain customers, it is also important to design for cabin space needs. Denel Aviation intends to build a South African Regional Aircraft (SARA) that will fly point-to-point, linking regional centres and intends to design aircraft seats that not only optimise passenger comfort, but which also save cabin space. The aim of this investigation was two-fold. The first aim was to determine how aircraft backrest angle affected passenger comfort, ease of seat access, perceived restriction and legroom, with different seat pan angles and seat heights. The second aim was to determine whether passenger comfort was affected with the most preferred backrest angle for each seat pan angle and seat height. Determining how seat pan angle and seat height affect the preferred angle of the backrest was considered important as Denel intend to use aircraft seats with a non-adjustable backrest angle. For this study, 80 participants were recruited from Rhodes University and the general Grahamstown population. The participants consisted of 40 males and 40 females and were not limited by race, ethnicity or culture. The participants were classified into two age groups; 18-30 years of age and 31-60 years of age. Participant stature, body mass, BMI and lower leg length was recorded to determine the effect these factors had on sitting comfort when the participants were seated in different seating conditions. From the results obtained, it was found that, by altering seat height, seat pan angle, and backrest angle, passenger comfort can be optimised. Furthermore, it was found that certain combinations of seat height, seat pan angle and backrest angle are more beneficial with regards to saving aircraft cabin space. However, this means that a compromise needs to be found for SARA as passenger comfort needs to be optimised, whilst decreasing the use of cabin space to reduce costs.
- Full Text:
- Date Issued: 2017
- Authors: Olley, Emma-Jane
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/19734 , vital:22479
- Description: Although aircraft cabin design has improved over the years, passengers continue to complain about sitting discomfort whilst flying. These complaints are often centred on the cramped and restricted seating conditions. Whilst passenger comfort is important, in order for airline companies to attract and retain customers, it is also important to design for cabin space needs. Denel Aviation intends to build a South African Regional Aircraft (SARA) that will fly point-to-point, linking regional centres and intends to design aircraft seats that not only optimise passenger comfort, but which also save cabin space. The aim of this investigation was two-fold. The first aim was to determine how aircraft backrest angle affected passenger comfort, ease of seat access, perceived restriction and legroom, with different seat pan angles and seat heights. The second aim was to determine whether passenger comfort was affected with the most preferred backrest angle for each seat pan angle and seat height. Determining how seat pan angle and seat height affect the preferred angle of the backrest was considered important as Denel intend to use aircraft seats with a non-adjustable backrest angle. For this study, 80 participants were recruited from Rhodes University and the general Grahamstown population. The participants consisted of 40 males and 40 females and were not limited by race, ethnicity or culture. The participants were classified into two age groups; 18-30 years of age and 31-60 years of age. Participant stature, body mass, BMI and lower leg length was recorded to determine the effect these factors had on sitting comfort when the participants were seated in different seating conditions. From the results obtained, it was found that, by altering seat height, seat pan angle, and backrest angle, passenger comfort can be optimised. Furthermore, it was found that certain combinations of seat height, seat pan angle and backrest angle are more beneficial with regards to saving aircraft cabin space. However, this means that a compromise needs to be found for SARA as passenger comfort needs to be optimised, whilst decreasing the use of cabin space to reduce costs.
- Full Text:
- Date Issued: 2017
The socio-economic contribution of non-timber forest product trade to households in four villages in Zomba and Machinga Districts, Malawi
- Authors: Mahonya, Sophie Manchichi
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4787 , vital:20724
- Description: The principal aim of this study was to assess the socio-economic contribution of nontimber forest product (NTFP) trade to households in Zomba and Machinga, southern Malawi. Quantitative and qualitative data were collected through several methods, including a household survey using questionnaire interviews, focus group discussions, key informant interviews with individual traders, direct observations, and literature review. The quantitative data were analysed statistically using SPPS version 16.0 while the qualitative data were analysed thematically. NTFP trade was the third important source of cash income for 15% of the households, although the level of use, buying and selling of NTFPs varied across the four study villages. All households in all the study villages used firewood (100%), and most used thatch grass (94%), bamboo (96%), wood for building (92%), largely as construction materials. However, the percentage of households buying NTFPs was lower, with the maximum percentage of households being 50%. The percent of households engaged in selling at least one NTFP was lower still at 39%. Substantial cash incomes were generated from firewood and edible orchids sales which provided up to a maximum of Mk180,000, equivalent to US$456, per year. Households joined the trade mostly for an alternative source of cash income due to poverty and to meet basic needs when other options were not available or feasible. Cash income generated from NTFP trade acted as a safety net and a coping strategy when other avenues supporting livelihoods were not accessible. The socio-economic benefits derived from NTFP trade were associated with the quantities collected, sold, market forces influenced by the law of demand and supply. The small amounts of cash income generated by most households were important as they supplemented household cash needs. There was a strong association between NTFP trade as one of the important sources of cash income and the number of months a household had food from their own garden in a year. There was a significant relationship though weak between ranking of NTFP trade and livestock ownership by households. Value chain analysis was used as an analytical tool to understand the processes involved in NTFP trade. The value chains for the products under study were short, dominated by traders and some intermediaries. Most of the products were sold in local markets with little value addition. This study recommends that policy makers should integrate NTFPs into their development plans, emphasizing the establishment of management strategies that will enhance availability and sustainability of the resource. NTFPs contributed to the livelihoods of the households socially and economically through provision of food, cash income, energy for cooking, medicine and construction materials.
- Full Text:
- Date Issued: 2017
- Authors: Mahonya, Sophie Manchichi
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4787 , vital:20724
- Description: The principal aim of this study was to assess the socio-economic contribution of nontimber forest product (NTFP) trade to households in Zomba and Machinga, southern Malawi. Quantitative and qualitative data were collected through several methods, including a household survey using questionnaire interviews, focus group discussions, key informant interviews with individual traders, direct observations, and literature review. The quantitative data were analysed statistically using SPPS version 16.0 while the qualitative data were analysed thematically. NTFP trade was the third important source of cash income for 15% of the households, although the level of use, buying and selling of NTFPs varied across the four study villages. All households in all the study villages used firewood (100%), and most used thatch grass (94%), bamboo (96%), wood for building (92%), largely as construction materials. However, the percentage of households buying NTFPs was lower, with the maximum percentage of households being 50%. The percent of households engaged in selling at least one NTFP was lower still at 39%. Substantial cash incomes were generated from firewood and edible orchids sales which provided up to a maximum of Mk180,000, equivalent to US$456, per year. Households joined the trade mostly for an alternative source of cash income due to poverty and to meet basic needs when other options were not available or feasible. Cash income generated from NTFP trade acted as a safety net and a coping strategy when other avenues supporting livelihoods were not accessible. The socio-economic benefits derived from NTFP trade were associated with the quantities collected, sold, market forces influenced by the law of demand and supply. The small amounts of cash income generated by most households were important as they supplemented household cash needs. There was a strong association between NTFP trade as one of the important sources of cash income and the number of months a household had food from their own garden in a year. There was a significant relationship though weak between ranking of NTFP trade and livestock ownership by households. Value chain analysis was used as an analytical tool to understand the processes involved in NTFP trade. The value chains for the products under study were short, dominated by traders and some intermediaries. Most of the products were sold in local markets with little value addition. This study recommends that policy makers should integrate NTFPs into their development plans, emphasizing the establishment of management strategies that will enhance availability and sustainability of the resource. NTFPs contributed to the livelihoods of the households socially and economically through provision of food, cash income, energy for cooking, medicine and construction materials.
- Full Text:
- Date Issued: 2017
Determinants of economic growth in China: 1978-2013
- Authors: Sipuka, Msingathi
- Date: 2016
- Subjects: China -- Economic conditions -- 1976-2000 , Economic development -- China
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: http://hdl.handle.net/10948/11181 , vital:26892
- Description: On 1 October 1949, the Communist Party of China under the leadership of Mao Zedong proclaimed the establishment of the People’s Republic of China. Mao was to lead the People’s Republic of China for the next twenty seven years until his death in 1976. During this twenty seven year period under Mao’s leadership the Communist Party of China consolidated its position as the leader of Chinese society and in so doing consolidated communist ideology as the central perspective that guided social and economic planning in China. In 1978, two years after Mao’s death, Deng Xiaping assumed the leadership of the Communist Party of China and this period marked the beginning of far reaching economic and social reforms in China. Over the next thirty years these reforms were to transform China’s economy from the tenth largest to the second largest in the world by the end of 2013. During this period China grew its manufacturing base to the extent that the country has become the world’s largest manufacturer and the world’s leading exporter. This transformation of China’s economy has translated to the country experiencing a period of high levels of economic growth over a sustained period of over 30 years. Estimates suggest that the country’s gross domestic product grew at an average annual rate of nearly 10% over a thirty year period from 1978. These high levels of economic growth have significantly contributed to the overall reduction of poverty levels in the country, with some estimates suggesting that between 300 million to 500 million of the country’s citizens have been lifted out of poverty over a period of thirty years. China’s economic growth has had an impact beyond its own borders, as growth in many developing countries has been inextricably linked to developments in the Chinese economy in particular its demand for raw materials.For developing countries that continue to grapple with high levels of poverty among its citizens, China’s experience of lifting such large numbers of its own citizens out of poverty at the back of high levels of economic growth over a period of thirty years must serve as a basis for some learnings. The primary purpose of this research is aimed at contributing towards building the basis for such learnings, particularly with regards to building an understanding of how China has been able to grow its economy at such high levels over a sustained period of time. This research aims to identify the determinants of China’s growth post 1978. The determinants of growth are studied particularly from 1978 because the year marks the beginning of the period of economic reforms.
- Full Text:
- Date Issued: 2016
- Authors: Sipuka, Msingathi
- Date: 2016
- Subjects: China -- Economic conditions -- 1976-2000 , Economic development -- China
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: http://hdl.handle.net/10948/11181 , vital:26892
- Description: On 1 October 1949, the Communist Party of China under the leadership of Mao Zedong proclaimed the establishment of the People’s Republic of China. Mao was to lead the People’s Republic of China for the next twenty seven years until his death in 1976. During this twenty seven year period under Mao’s leadership the Communist Party of China consolidated its position as the leader of Chinese society and in so doing consolidated communist ideology as the central perspective that guided social and economic planning in China. In 1978, two years after Mao’s death, Deng Xiaping assumed the leadership of the Communist Party of China and this period marked the beginning of far reaching economic and social reforms in China. Over the next thirty years these reforms were to transform China’s economy from the tenth largest to the second largest in the world by the end of 2013. During this period China grew its manufacturing base to the extent that the country has become the world’s largest manufacturer and the world’s leading exporter. This transformation of China’s economy has translated to the country experiencing a period of high levels of economic growth over a sustained period of over 30 years. Estimates suggest that the country’s gross domestic product grew at an average annual rate of nearly 10% over a thirty year period from 1978. These high levels of economic growth have significantly contributed to the overall reduction of poverty levels in the country, with some estimates suggesting that between 300 million to 500 million of the country’s citizens have been lifted out of poverty over a period of thirty years. China’s economic growth has had an impact beyond its own borders, as growth in many developing countries has been inextricably linked to developments in the Chinese economy in particular its demand for raw materials.For developing countries that continue to grapple with high levels of poverty among its citizens, China’s experience of lifting such large numbers of its own citizens out of poverty at the back of high levels of economic growth over a period of thirty years must serve as a basis for some learnings. The primary purpose of this research is aimed at contributing towards building the basis for such learnings, particularly with regards to building an understanding of how China has been able to grow its economy at such high levels over a sustained period of time. This research aims to identify the determinants of China’s growth post 1978. The determinants of growth are studied particularly from 1978 because the year marks the beginning of the period of economic reforms.
- Full Text:
- Date Issued: 2016
Synthesis and structural studies of NiS and PdS nanoparticles/nanocomposites from dithiocarbamates single source precursors
- Authors: Nqombolo, Azile
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc (Chemistry)
- Identifier: vital:11359 , http://hdl.handle.net/10353/d1021326
- Description: The main aim of this research is to synthesize Ni(II) and Pd(II) dithiocarbamate complexes and use them as single source precursors for the synthesis of NiS and PdS nanoparticles and metal sulphides potato starch nanocomposites. Four dithiocarbamate ligands were synthesized and characterized using elemental analysis and spectroscopic techniques. The ligands were used to prepared homoleptic Ni(II) and Pd(II) complexes of the dithiocarbamate ligands. The metal complexes were characterized with elemental analysis, UV-Vis, FTIR and 1H-NMR spectroscopic techniques. Conductivity measurements indicate that all the complexes are non-electrolytes in solution and results from the electronic spectra studies confirmed the proposed 4-coordinate square planar geometry around the metal ions. The nickel complexes showed d-d transitions around 477 nm while in the palladium complexes, no d-d transitions were observed but the compounds showed strong metal to ligand charge transfer transitions. From the FTIR spectra studies, it can be confirmed that the complexes were successfully synthesised because all peaks of interest were observed at expected regions from the literature. The νC-N was observed around 1469-1495 cm-1, νC=S around 1101-1188 cm-1 and νC-S around 738-1060 cm-1 for both Ni(II) and Pd(II) complexes. νNi-S was observed around 375-543 cm-1 and νPd-S around 529-545 cm-1. The FTIR also confirmed that the dithiocarbamate ligands act as bidentate chelating ligands through the sulfur atoms. The complexes were used as single source precursors and thermolysed in hexadecylamine (HDA) at 220 °C to prepare four HDA-capped nickel sulfide nanoparticles and four palladium sulfide nanoparticles. The as-prepared nanoparticles were studied with optical absorption spectra, photoluminescence, powder X-ray diffraction (PXRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). The optical studies results showed that NiS have large band gaps that are greater than that of the bulk, therefore they are found to be blue shifted relative to the bulk, which shows that they have small particle size and thus confirming their quantum confinement effect. PL spectra reveal that the emission peaks are red shifted compared to the absorption band edges of the nanoparticles. The XRD patterns confirmed the formation of cubic and rhombohedral phase for NiS nanoparticles and cubic phase for PdS nanoparticles. SEM images of both NiS and PdS show uniform surface morphology at low and high magnification with different shapes. EDS analyses confirmed the presence of Ni, S, and Pd in each of the spectrum indicating that the nanoparticles were successfully synthesized. TEM images showed that the synthesised nanoparticles have uniform and narrow size distribution with no agglomeration. The sizes of the NiS nanoparticles were found to be in the range of 12-38 nm for NiS1, 8-11 nm for NiS2, 9-16 nm for NiS3 and 4-9 nm for NiS4. The TEM images for the as-prepared PdS nanoparticles showed that the average crystallite sizes are 6.94-9.62 nm for PdS1, 8-11 nm for PdS2, 9-16 nm for PdS3 and 4-9 nm for PdS4 respectively. The nanoparticles were used to prepare potato starch nanocomposites and SEM images indicate that the surface morphology of starch polymer nanocomposites compose of potato starch and few particles in between the pores of the matrix, this is due to the small ratio of nanoparticles used.
- Full Text:
- Date Issued: 2016
- Authors: Nqombolo, Azile
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc (Chemistry)
- Identifier: vital:11359 , http://hdl.handle.net/10353/d1021326
- Description: The main aim of this research is to synthesize Ni(II) and Pd(II) dithiocarbamate complexes and use them as single source precursors for the synthesis of NiS and PdS nanoparticles and metal sulphides potato starch nanocomposites. Four dithiocarbamate ligands were synthesized and characterized using elemental analysis and spectroscopic techniques. The ligands were used to prepared homoleptic Ni(II) and Pd(II) complexes of the dithiocarbamate ligands. The metal complexes were characterized with elemental analysis, UV-Vis, FTIR and 1H-NMR spectroscopic techniques. Conductivity measurements indicate that all the complexes are non-electrolytes in solution and results from the electronic spectra studies confirmed the proposed 4-coordinate square planar geometry around the metal ions. The nickel complexes showed d-d transitions around 477 nm while in the palladium complexes, no d-d transitions were observed but the compounds showed strong metal to ligand charge transfer transitions. From the FTIR spectra studies, it can be confirmed that the complexes were successfully synthesised because all peaks of interest were observed at expected regions from the literature. The νC-N was observed around 1469-1495 cm-1, νC=S around 1101-1188 cm-1 and νC-S around 738-1060 cm-1 for both Ni(II) and Pd(II) complexes. νNi-S was observed around 375-543 cm-1 and νPd-S around 529-545 cm-1. The FTIR also confirmed that the dithiocarbamate ligands act as bidentate chelating ligands through the sulfur atoms. The complexes were used as single source precursors and thermolysed in hexadecylamine (HDA) at 220 °C to prepare four HDA-capped nickel sulfide nanoparticles and four palladium sulfide nanoparticles. The as-prepared nanoparticles were studied with optical absorption spectra, photoluminescence, powder X-ray diffraction (PXRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). The optical studies results showed that NiS have large band gaps that are greater than that of the bulk, therefore they are found to be blue shifted relative to the bulk, which shows that they have small particle size and thus confirming their quantum confinement effect. PL spectra reveal that the emission peaks are red shifted compared to the absorption band edges of the nanoparticles. The XRD patterns confirmed the formation of cubic and rhombohedral phase for NiS nanoparticles and cubic phase for PdS nanoparticles. SEM images of both NiS and PdS show uniform surface morphology at low and high magnification with different shapes. EDS analyses confirmed the presence of Ni, S, and Pd in each of the spectrum indicating that the nanoparticles were successfully synthesized. TEM images showed that the synthesised nanoparticles have uniform and narrow size distribution with no agglomeration. The sizes of the NiS nanoparticles were found to be in the range of 12-38 nm for NiS1, 8-11 nm for NiS2, 9-16 nm for NiS3 and 4-9 nm for NiS4. The TEM images for the as-prepared PdS nanoparticles showed that the average crystallite sizes are 6.94-9.62 nm for PdS1, 8-11 nm for PdS2, 9-16 nm for PdS3 and 4-9 nm for PdS4 respectively. The nanoparticles were used to prepare potato starch nanocomposites and SEM images indicate that the surface morphology of starch polymer nanocomposites compose of potato starch and few particles in between the pores of the matrix, this is due to the small ratio of nanoparticles used.
- Full Text:
- Date Issued: 2016
Biotechnology from bench to market: the design, scale-up and commercialisation strategy development of a disruptive bioprocess for potable ethanol production
- Authors: Dhanani, Karim Colin Hassan
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/55863 , vital:26750
- Description: The capacity of research institutions to engage in technology transfer activities has important implications on both economic development and technological advancement. This thesis explores the developmental and commercialisation processes involved in the transfer of a potentially disruptive bioprocessing technology for beverage alcohol production. Ethanolic fermentation strategies are of interest due to their global economic importance and their potential to produce clean renewable fuels in the future. Currently used methods are both energetically wasteful and economically inefficient. To this end more effective bioprocessing methods and implementation strategies are required to enable commercially viable decentralised small-scale ethanol production. Perfusion reactors have a number of advantages over batch and other continuous fermentation strategies. This study aimed to develop and study the fermentative efficiency of a perfusion tower bioreactor system at the bench scale, and subsequently through a scale up process to a low level commercial capacity. An HPLC method was developed for the Simultaneous quantification of common fermentation analytes; this was used to determine bench scale fermentation efficacies over an operational period. At steady state the ethanol volumetric productivity of the bench scale bioreactor system was 3.40 g. L-1.h-1, the average yield of ethanol to consumed sugar was 0.467 g.g -1, with an average sugar conversion percentage of 96%. Results showed that the tower perfusion bioreactor was appropriate for high performance ethyl alcohol fermentations. This reactor design was then scaled up to pilot scale and then commercial scale ca pacity. Similar efficienCies were achieved with these larger systems. Based on the process performance data obtained, a commercialisation strategy was developed and market performance was projected. It was found that productivity rates per unit volume were favourable, and the bioreactor system was determined to be very cost effective for a decentralised ethanolic beverage manufacturing model.
- Full Text:
- Date Issued: 2015
- Authors: Dhanani, Karim Colin Hassan
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/55863 , vital:26750
- Description: The capacity of research institutions to engage in technology transfer activities has important implications on both economic development and technological advancement. This thesis explores the developmental and commercialisation processes involved in the transfer of a potentially disruptive bioprocessing technology for beverage alcohol production. Ethanolic fermentation strategies are of interest due to their global economic importance and their potential to produce clean renewable fuels in the future. Currently used methods are both energetically wasteful and economically inefficient. To this end more effective bioprocessing methods and implementation strategies are required to enable commercially viable decentralised small-scale ethanol production. Perfusion reactors have a number of advantages over batch and other continuous fermentation strategies. This study aimed to develop and study the fermentative efficiency of a perfusion tower bioreactor system at the bench scale, and subsequently through a scale up process to a low level commercial capacity. An HPLC method was developed for the Simultaneous quantification of common fermentation analytes; this was used to determine bench scale fermentation efficacies over an operational period. At steady state the ethanol volumetric productivity of the bench scale bioreactor system was 3.40 g. L-1.h-1, the average yield of ethanol to consumed sugar was 0.467 g.g -1, with an average sugar conversion percentage of 96%. Results showed that the tower perfusion bioreactor was appropriate for high performance ethyl alcohol fermentations. This reactor design was then scaled up to pilot scale and then commercial scale ca pacity. Similar efficienCies were achieved with these larger systems. Based on the process performance data obtained, a commercialisation strategy was developed and market performance was projected. It was found that productivity rates per unit volume were favourable, and the bioreactor system was determined to be very cost effective for a decentralised ethanolic beverage manufacturing model.
- Full Text:
- Date Issued: 2015
Reconceptualising notions of South African Indianess : a personal narrative
- Authors: Kunvar, Yogita
- Date: 2015
- Subjects: East Indians -- South Africa , East Indians -- South Africa -- Ethnic identity , East Indians -- Cultural assimilation -- South Africa , National characteristics, East Indian , East Indian diaspora , Identity (Psychology) , South Africa -- Social conditions -- 1961-1994 , South Africa -- Politics and government -- 1948-1994 , South Africa -- Race relations
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2123 , http://hdl.handle.net/10962/d1017767
- Description: The theoretical challenge of conceptualising South African Indianess is suffused with a plethora of variables that suggest complexity. While being misleadingly homogenous, Indian identity encompasses a multitude of expressions. This thesis seeks to reconceptualise notions of South African Indianess through personal narrative. The research context is contemporary South Africa with a specific focus on Johannesburg’s East Rand Reef. Inspired by the dearth of literature on contemporary Indianess this study addresses the gap in the present discourse. Following the autoethnographic work of Motzafi-Haller (1997) and Narayan (1993) the thesis presents a layered narrative by juxtaposing the experiences of research participants with my own. Using multi-sited autoethnographic data the thesis explores the question of what it means to be Indian in relation to South Africa’s Apartheid past. By drawing on concepts in popular diaspora theory and critiquing their application, the thesis illustrates the inadequacies inherent in the definitions of diaspora and suggests a broader understanding of its application. Through exploring layers of Indianess the thesis illustrates the inherent complexity in reconceptualising South African Indianess. The study suggests that as a result of changing global and local flows, South African Indians are reconceptualising what it means to be South African Indian.
- Full Text:
- Date Issued: 2015
- Authors: Kunvar, Yogita
- Date: 2015
- Subjects: East Indians -- South Africa , East Indians -- South Africa -- Ethnic identity , East Indians -- Cultural assimilation -- South Africa , National characteristics, East Indian , East Indian diaspora , Identity (Psychology) , South Africa -- Social conditions -- 1961-1994 , South Africa -- Politics and government -- 1948-1994 , South Africa -- Race relations
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2123 , http://hdl.handle.net/10962/d1017767
- Description: The theoretical challenge of conceptualising South African Indianess is suffused with a plethora of variables that suggest complexity. While being misleadingly homogenous, Indian identity encompasses a multitude of expressions. This thesis seeks to reconceptualise notions of South African Indianess through personal narrative. The research context is contemporary South Africa with a specific focus on Johannesburg’s East Rand Reef. Inspired by the dearth of literature on contemporary Indianess this study addresses the gap in the present discourse. Following the autoethnographic work of Motzafi-Haller (1997) and Narayan (1993) the thesis presents a layered narrative by juxtaposing the experiences of research participants with my own. Using multi-sited autoethnographic data the thesis explores the question of what it means to be Indian in relation to South Africa’s Apartheid past. By drawing on concepts in popular diaspora theory and critiquing their application, the thesis illustrates the inadequacies inherent in the definitions of diaspora and suggests a broader understanding of its application. Through exploring layers of Indianess the thesis illustrates the inherent complexity in reconceptualising South African Indianess. The study suggests that as a result of changing global and local flows, South African Indians are reconceptualising what it means to be South African Indian.
- Full Text:
- Date Issued: 2015
The design of Makana monument in Grahamstown: pathway of memory inspired by nature, mediating public and sacred space, as a regenerative mechanism of a forgotten place
- Authors: Almon, Peta Pryor
- Date: 2015
- Subjects: Monuments -- South Africa -- Grahamstown Historic buildings -- South Africa -- Grahamstown , Historic sites -- South Africa -- Grahamstown Architecture and society -- History -- 21st century
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/41283 , vital:36431
- Description: Since 1994 the post-apartheid heritage discourse has become one of the primary tools to deal with culture, identity and citizenship in South Africa. It is one of the means by which a democratic national identity is being forged and the production of new monuments is the physical manifestation of this discourse. The South African landscape holds many suppressed or unarticulated histories; histories which are a function of socio-political and land battles throughout the years of colonisation and apartheid. In society, socio-political ideals are supported by daily practices, which in turn affect social structures. These structures and the values that they uphold, in turn are interned in the monument. The monument then radiates these through its physical form. Monuments are therefore a collective mirror from which society can position itself, expressing socio-political ideals that are reinforced by community actions. This treatise explores monument as a mechanism of social regeneration towards the vision of a democratic landscape. The treatise investigates the making of monuments by analysing philosophical positions, characteristics with the intention of extracting principles, and types of monuments. This was done in order to gain an understanding as to why monuments exist, the fundamental principles involved, and the architectural approaches to these. The work is centred around Grahamstown, focusing on heritage within the city. This heritage is explicitly represented in over seventy sites within the city. Through an analysis of these heritage sites, it became clear that there is an imbalance of represented histories; mainly favouring the colonial histories while the African histories remain unarticulated or poorly represented. This imbalance is testimony to the socio-political ideals over time which in turn affected the morphology of the city over time. This resulted in contrasting spatial structures; the colonial side of town structured by a grid plan centred on a major axial route from which the spatial hierarchy extends, and the township side which is characterised by a repetitive, non-hierarchical grid layout. The landscape of the city underpins this spatial layout where features are used to enforce socio-political ideals. The structuring elements of the landscape are crucial in this regard. Surrounding hills create a bowl condition in which the city is located which in turn is divided in half by a river reinforcing the two sides of the city. Two entry points into the city are demarcated by prominent hills, positioned directly opposite each other on either side of the city. Gunfire Hill on the west is accentuated by the 1820 Settlers Monument, while opposite to the east is Makana’s Kop surrounded by the township and remains unarticulated and known only by oral histories. This clear imbalance in the representation of histories is commonly characteristic in the South African landscape and settlement patterns. The treatise seeks to arrive at an architectural intervention that is a step towards reducing this imbalance, as well as representing these suppressed histories appropriately. Vincent Scully’s notion of architecture mimicking nature was used as a theoretical lens through which the approach to the architecure and landscape were viewed. Consequently, phenomenological ideas are used as an architectural approach which aims to integrate people, nature and heritage in the form of a monument. In line with this, African traditions and beliefs were investigated, specifically the inherent relationship between nature, human spirit and settlement. The proposal is the Makana Monument located on Makana’s Kop, maintining the principles of monuments while facilitating the social needs of the surrounding community within the township of Hlalani. The site is physically monumental in nature, due to its steep slope and prominent tree line. Presented with a naturally sacred site that is positoned at the centre of a community and contains significant history pertaining to Grahamstown. These themes became the informants of the design. The aim is to maintain the natural vertical prominence of the site by creating a building that gives definition through contrasting horizontal retaining walls positioned along the contour lines. Located at a crucial point on the slope, it mediates public and sacred space. Routes through and into the building are informed by the energies of existing desire lines of people’s pathways. The intention of the building is to give dignity to a sacred natural landscape, facilitate the needs of the community, and appropriately recognise the supressed heritage.
- Full Text:
- Date Issued: 2015
- Authors: Almon, Peta Pryor
- Date: 2015
- Subjects: Monuments -- South Africa -- Grahamstown Historic buildings -- South Africa -- Grahamstown , Historic sites -- South Africa -- Grahamstown Architecture and society -- History -- 21st century
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/41283 , vital:36431
- Description: Since 1994 the post-apartheid heritage discourse has become one of the primary tools to deal with culture, identity and citizenship in South Africa. It is one of the means by which a democratic national identity is being forged and the production of new monuments is the physical manifestation of this discourse. The South African landscape holds many suppressed or unarticulated histories; histories which are a function of socio-political and land battles throughout the years of colonisation and apartheid. In society, socio-political ideals are supported by daily practices, which in turn affect social structures. These structures and the values that they uphold, in turn are interned in the monument. The monument then radiates these through its physical form. Monuments are therefore a collective mirror from which society can position itself, expressing socio-political ideals that are reinforced by community actions. This treatise explores monument as a mechanism of social regeneration towards the vision of a democratic landscape. The treatise investigates the making of monuments by analysing philosophical positions, characteristics with the intention of extracting principles, and types of monuments. This was done in order to gain an understanding as to why monuments exist, the fundamental principles involved, and the architectural approaches to these. The work is centred around Grahamstown, focusing on heritage within the city. This heritage is explicitly represented in over seventy sites within the city. Through an analysis of these heritage sites, it became clear that there is an imbalance of represented histories; mainly favouring the colonial histories while the African histories remain unarticulated or poorly represented. This imbalance is testimony to the socio-political ideals over time which in turn affected the morphology of the city over time. This resulted in contrasting spatial structures; the colonial side of town structured by a grid plan centred on a major axial route from which the spatial hierarchy extends, and the township side which is characterised by a repetitive, non-hierarchical grid layout. The landscape of the city underpins this spatial layout where features are used to enforce socio-political ideals. The structuring elements of the landscape are crucial in this regard. Surrounding hills create a bowl condition in which the city is located which in turn is divided in half by a river reinforcing the two sides of the city. Two entry points into the city are demarcated by prominent hills, positioned directly opposite each other on either side of the city. Gunfire Hill on the west is accentuated by the 1820 Settlers Monument, while opposite to the east is Makana’s Kop surrounded by the township and remains unarticulated and known only by oral histories. This clear imbalance in the representation of histories is commonly characteristic in the South African landscape and settlement patterns. The treatise seeks to arrive at an architectural intervention that is a step towards reducing this imbalance, as well as representing these suppressed histories appropriately. Vincent Scully’s notion of architecture mimicking nature was used as a theoretical lens through which the approach to the architecure and landscape were viewed. Consequently, phenomenological ideas are used as an architectural approach which aims to integrate people, nature and heritage in the form of a monument. In line with this, African traditions and beliefs were investigated, specifically the inherent relationship between nature, human spirit and settlement. The proposal is the Makana Monument located on Makana’s Kop, maintining the principles of monuments while facilitating the social needs of the surrounding community within the township of Hlalani. The site is physically monumental in nature, due to its steep slope and prominent tree line. Presented with a naturally sacred site that is positoned at the centre of a community and contains significant history pertaining to Grahamstown. These themes became the informants of the design. The aim is to maintain the natural vertical prominence of the site by creating a building that gives definition through contrasting horizontal retaining walls positioned along the contour lines. Located at a crucial point on the slope, it mediates public and sacred space. Routes through and into the building are informed by the energies of existing desire lines of people’s pathways. The intention of the building is to give dignity to a sacred natural landscape, facilitate the needs of the community, and appropriately recognise the supressed heritage.
- Full Text:
- Date Issued: 2015
Practitioners' views of the Griffiths scales : informing the revision process
- Authors: Samuel, Candice
- Date: 2014
- Subjects: Psychological tests for children -- South Africa , Griffiths Developmental Scales , Child development -- Testing
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9975 , http://hdl.handle.net/10948/d1021062
- Description: The Association for Research in Infant and Child Development (ARICD) is currently in the process of revising the Griffiths Scales. When revising measures, obtaining practitioners’ views on the measure is common practice. The purpose of the present study was to explore the themes emerging from a group of practitioners surveyed on their opinions about the Griffiths Scales in order to inform the Griffiths Scales revision process. A qualitative, survey methodology was used. A survey questionnaire was designed and distributed by the ARICD to ascertain practitioners’ and researchers’ views on assessing child development, insights into practicalities and the usability of the Griffiths Scales, as well as their opinions on potential changes and improvements. Data were also gathered on the frequency, purpose and age range with which practitioners used the Griffiths Scales. The questionnaire was distributed to Registered Griffiths Scales Users (practitioners) via the ARICD members’ email distribution list. The practitioners and researchers were either current or past users of the Griffiths Scales. Eighty-five completed questionnaires were returned of which 52 were from current, regular users of the Griffiths Scales and 33 were from non-users. The data obtained from the 85 returned questionnaires were analysed in the present research study using thematic analysis to extract themes for both users and non-users of the Griffiths Scales. The results of the data analysis revealed four over-arching themes, namely, purpose and use of the Griffiths Scales; domains, content, and structure of the Griffiths Scales; psychometric properties, standardisation, and norms; and merits, limitations, and improvements. Based on the themed views of practitioners, recommendations were made regarding the support for the next revision cycle as well as strengths of the Griffiths Scales that should be retained and improvements and additions needed. It is hoped that these recommendations will guide aspects of the revision process. Consequently, the recommendations have been submitted to the Project Board.
- Full Text:
- Date Issued: 2014
- Authors: Samuel, Candice
- Date: 2014
- Subjects: Psychological tests for children -- South Africa , Griffiths Developmental Scales , Child development -- Testing
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9975 , http://hdl.handle.net/10948/d1021062
- Description: The Association for Research in Infant and Child Development (ARICD) is currently in the process of revising the Griffiths Scales. When revising measures, obtaining practitioners’ views on the measure is common practice. The purpose of the present study was to explore the themes emerging from a group of practitioners surveyed on their opinions about the Griffiths Scales in order to inform the Griffiths Scales revision process. A qualitative, survey methodology was used. A survey questionnaire was designed and distributed by the ARICD to ascertain practitioners’ and researchers’ views on assessing child development, insights into practicalities and the usability of the Griffiths Scales, as well as their opinions on potential changes and improvements. Data were also gathered on the frequency, purpose and age range with which practitioners used the Griffiths Scales. The questionnaire was distributed to Registered Griffiths Scales Users (practitioners) via the ARICD members’ email distribution list. The practitioners and researchers were either current or past users of the Griffiths Scales. Eighty-five completed questionnaires were returned of which 52 were from current, regular users of the Griffiths Scales and 33 were from non-users. The data obtained from the 85 returned questionnaires were analysed in the present research study using thematic analysis to extract themes for both users and non-users of the Griffiths Scales. The results of the data analysis revealed four over-arching themes, namely, purpose and use of the Griffiths Scales; domains, content, and structure of the Griffiths Scales; psychometric properties, standardisation, and norms; and merits, limitations, and improvements. Based on the themed views of practitioners, recommendations were made regarding the support for the next revision cycle as well as strengths of the Griffiths Scales that should be retained and improvements and additions needed. It is hoped that these recommendations will guide aspects of the revision process. Consequently, the recommendations have been submitted to the Project Board.
- Full Text:
- Date Issued: 2014
The leadership competencies subordinates value : an exploratory study across gender and national culture
- Authors: Gondongwe, Sharon
- Date: 2014
- Subjects: Leadership , Organizational behavior , Organizational behavior -- Cross-cultural studies , Organizational behavior -- Sex differences
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1203 , http://hdl.handle.net/10962/d1015673
- Description: The effectiveness of leadership is largely dependent on whether the leadership competencies exhibited by leaders are congruent with the value system endorsed by subordinates. One of the ways in which leaders can influence subordinates is by understanding the leadership competencies valued by subordinates. Gender and national culture are two of the many factors that have an influence on the leadership competencies valued by subordinates. A large amount of research has been conducted to determine if, indeed, gender and national culture influence the leadership competencies subordinates' value. However, most of this research has been conducted in Europe and North America, places in which national cultures differ significantly from those prevailing in African countries. This study, from a South African and Zimbabwean perspective, attempted to ascertain if gender and national culture influence the leadership competencies they value in their leaders. Existing studies have indicated that gender and national culture do not influence the leadership competencies valued in a leader. The findings of this study are in accordance with previous research and agree that gender and national culture do not influence the leadership competencies valued in a leader. The results of this study indicated that male and female subordinates value similar leadership competencies. With respect to national culture, both South African and Zimbabwean subordinates value similar leadership competencies. Based on the findings of this study, regardless of gender and national culture, all subordinates value a leader who is loyal, visionary, openly embodies integrity, and is a leader who empowers subordinates.
- Full Text:
- Date Issued: 2014
- Authors: Gondongwe, Sharon
- Date: 2014
- Subjects: Leadership , Organizational behavior , Organizational behavior -- Cross-cultural studies , Organizational behavior -- Sex differences
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1203 , http://hdl.handle.net/10962/d1015673
- Description: The effectiveness of leadership is largely dependent on whether the leadership competencies exhibited by leaders are congruent with the value system endorsed by subordinates. One of the ways in which leaders can influence subordinates is by understanding the leadership competencies valued by subordinates. Gender and national culture are two of the many factors that have an influence on the leadership competencies valued by subordinates. A large amount of research has been conducted to determine if, indeed, gender and national culture influence the leadership competencies subordinates' value. However, most of this research has been conducted in Europe and North America, places in which national cultures differ significantly from those prevailing in African countries. This study, from a South African and Zimbabwean perspective, attempted to ascertain if gender and national culture influence the leadership competencies they value in their leaders. Existing studies have indicated that gender and national culture do not influence the leadership competencies valued in a leader. The findings of this study are in accordance with previous research and agree that gender and national culture do not influence the leadership competencies valued in a leader. The results of this study indicated that male and female subordinates value similar leadership competencies. With respect to national culture, both South African and Zimbabwean subordinates value similar leadership competencies. Based on the findings of this study, regardless of gender and national culture, all subordinates value a leader who is loyal, visionary, openly embodies integrity, and is a leader who empowers subordinates.
- Full Text:
- Date Issued: 2014
Whither state, private or public service broadcasting? : an analysis of the construction of news on ZBC TV during the 2002 presidential election campaign in Zimbabwe
- Authors: Dlamini, Tula
- Date: 2013-07-16
- Subjects: Zimbabwe Broadcasting Corporation Journalism -- Political aspects -- Zimbabwe Mass media -- Political aspects -- Zimbabwe Political campaigns -- Zimbabwe Elections -- Zimbabwe Television and politics -- Zimbabwe Zimbabwe -- Politics and government -- 1980-
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3520 , http://hdl.handle.net/10962/d1008257
- Description: The study sets out to examine the television coverage of the 2002 presidential campaign in Zimbabwe by examining the extent to which the Zimbabwe Broadcasting Corporation fulfilled the mandate of public service broadcasting. The primary objective of this study is to assess how ZBC television newscasts mediated pluralistic politics in the coverage of the country's presidential election campaign, in line with the normative public sphere principles. The thesis comprises seven chapters organized, first, with an introductory chapter, which provides the general background of the study. The chapter offers the rationale for the focus on TV rather than other media fomls . There are two theoretical and contextual chapters in which the use of both qualitative and quantitative methods is explained and findings are presented. Finally, the conclusion offers recommendations about the form broadcasting might take to fulfil a public service mandate and these include the strengthening of the public service broadcasting model along normative public sphere principles. The findings of the analysed election newscasts confirm that ZBC television election news was constructed in favour of ZANU PF at the expense of voices from other social and political constituencies. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Authors: Dlamini, Tula
- Date: 2013-07-16
- Subjects: Zimbabwe Broadcasting Corporation Journalism -- Political aspects -- Zimbabwe Mass media -- Political aspects -- Zimbabwe Political campaigns -- Zimbabwe Elections -- Zimbabwe Television and politics -- Zimbabwe Zimbabwe -- Politics and government -- 1980-
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3520 , http://hdl.handle.net/10962/d1008257
- Description: The study sets out to examine the television coverage of the 2002 presidential campaign in Zimbabwe by examining the extent to which the Zimbabwe Broadcasting Corporation fulfilled the mandate of public service broadcasting. The primary objective of this study is to assess how ZBC television newscasts mediated pluralistic politics in the coverage of the country's presidential election campaign, in line with the normative public sphere principles. The thesis comprises seven chapters organized, first, with an introductory chapter, which provides the general background of the study. The chapter offers the rationale for the focus on TV rather than other media fomls . There are two theoretical and contextual chapters in which the use of both qualitative and quantitative methods is explained and findings are presented. Finally, the conclusion offers recommendations about the form broadcasting might take to fulfil a public service mandate and these include the strengthening of the public service broadcasting model along normative public sphere principles. The findings of the analysed election newscasts confirm that ZBC television election news was constructed in favour of ZANU PF at the expense of voices from other social and political constituencies. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
Explaining the endurance of poverty and inequality : social policy and the social division of welfare in the South African health system
- Authors: Du Plessis, Ulandi
- Date: 2013
- Subjects: Health system , Private health , Public health , Poor , Subsidies , Profit motive , Quality , Efficiency , Public health -- Finance -- Research -- South Africa , Medical care -- Research -- South Africa , Poverty -- Research -- South Africa , Equality -- Research -- South Africa , South Africa -- Social conditions
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2755 , http://hdl.handle.net/10962/d1002002
- Description: This thesis examines the structure and flow of public funding between the public and private sectors in the South African health system and the consequences thereof for the achievement of equity. The conceptual framework used to undertake the analysis derives from Richard Titmuss’ core theoretical framework, the Social Division of Welfare. The application of the Social Division of Welfare applied to the South African health care context demonstrates how state resources end up benefitting the non-poor and, as a result, reproduce inequality. Those who access public institutions such as public health care are assumed to be ‘dependent’ on the state, whilst those who access private health facilities claim to be ‘independent’ of the state. However, this thesis shows that these assumptions are flawed. Access to the formal labour market, and subsequently the paying of taxes, authorises one to access state subsidies not available to those who do not. The application of the Social Division of Welfare shows that tax-paying private health care patients benefit considerably from state resources. This thesis argues that due to cost escalation in the private health sector, a consequence of the commodification of health care, these private health care ‘consumers’ as well as the private health industry in general are dependent upon state resources. This thesis analyses the role played by the profit motive present in the private health industry and the consequences for equity, quality, access and efficiency in health care provision
- Full Text:
- Date Issued: 2013
- Authors: Du Plessis, Ulandi
- Date: 2013
- Subjects: Health system , Private health , Public health , Poor , Subsidies , Profit motive , Quality , Efficiency , Public health -- Finance -- Research -- South Africa , Medical care -- Research -- South Africa , Poverty -- Research -- South Africa , Equality -- Research -- South Africa , South Africa -- Social conditions
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2755 , http://hdl.handle.net/10962/d1002002
- Description: This thesis examines the structure and flow of public funding between the public and private sectors in the South African health system and the consequences thereof for the achievement of equity. The conceptual framework used to undertake the analysis derives from Richard Titmuss’ core theoretical framework, the Social Division of Welfare. The application of the Social Division of Welfare applied to the South African health care context demonstrates how state resources end up benefitting the non-poor and, as a result, reproduce inequality. Those who access public institutions such as public health care are assumed to be ‘dependent’ on the state, whilst those who access private health facilities claim to be ‘independent’ of the state. However, this thesis shows that these assumptions are flawed. Access to the formal labour market, and subsequently the paying of taxes, authorises one to access state subsidies not available to those who do not. The application of the Social Division of Welfare shows that tax-paying private health care patients benefit considerably from state resources. This thesis argues that due to cost escalation in the private health sector, a consequence of the commodification of health care, these private health care ‘consumers’ as well as the private health industry in general are dependent upon state resources. This thesis analyses the role played by the profit motive present in the private health industry and the consequences for equity, quality, access and efficiency in health care provision
- Full Text:
- Date Issued: 2013
Perceived usefulness of agricultural information sought on-line and broadcast in rural Mozambique: a case study of two Community Multimedia Centres (CMCs)
- Authors: Fuel, Isaias Carlos
- Date: 2013
- Subjects: Radio in community development -- Mozambique Radio broadcasting -- Mozambique Radio stations -- Mozambique Digital media -- Mozambique Rural development -- Mozambique Agriculture -- Mozambique
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3505 , http://hdl.handle.net/10962/d1007240
- Description: The wealth of information available on the Internet holds the potential to aid development in Africa. In order to be effective, such information needs to be contextualised to respond to local needs and practices. The combination of old and new media can support uptake and improve acceptance of new technologies in developing countries. The purpose of this qualitative study was to investigate the perceived usefulness of agricultural information sought on-line and broadcast via community radio in the two Community Multimedia Centres (CMCs) of Namaacha and Murrombene, in rural Mozambique. The data was generated from focus group discussion, individual interview, document analysis, and observation involving farmers and radio presenters. The study has shown that on-line agricultural information responds to the needs of the farmers because it contributes to eliminate pests and help farmers to make decisions about their activities. The study has also shown that there is a communication gap between farmers, extension workers, and volunteer reporters working at the community radios of the two CMCs. Volunteers have no agricultural knowledge. The problem this creates manifests itself primarily when they try to translate on-line agricultural information from Portuguese into local languages. Farmers have difficulties expressing their problems. Extension workers are not available to act as experts and mediators between volunteers and farmers. A collaborative website focusing on locally relevant content was suggested as a possible improvement.
- Full Text:
- Date Issued: 2013
- Authors: Fuel, Isaias Carlos
- Date: 2013
- Subjects: Radio in community development -- Mozambique Radio broadcasting -- Mozambique Radio stations -- Mozambique Digital media -- Mozambique Rural development -- Mozambique Agriculture -- Mozambique
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3505 , http://hdl.handle.net/10962/d1007240
- Description: The wealth of information available on the Internet holds the potential to aid development in Africa. In order to be effective, such information needs to be contextualised to respond to local needs and practices. The combination of old and new media can support uptake and improve acceptance of new technologies in developing countries. The purpose of this qualitative study was to investigate the perceived usefulness of agricultural information sought on-line and broadcast via community radio in the two Community Multimedia Centres (CMCs) of Namaacha and Murrombene, in rural Mozambique. The data was generated from focus group discussion, individual interview, document analysis, and observation involving farmers and radio presenters. The study has shown that on-line agricultural information responds to the needs of the farmers because it contributes to eliminate pests and help farmers to make decisions about their activities. The study has also shown that there is a communication gap between farmers, extension workers, and volunteer reporters working at the community radios of the two CMCs. Volunteers have no agricultural knowledge. The problem this creates manifests itself primarily when they try to translate on-line agricultural information from Portuguese into local languages. Farmers have difficulties expressing their problems. Extension workers are not available to act as experts and mediators between volunteers and farmers. A collaborative website focusing on locally relevant content was suggested as a possible improvement.
- Full Text:
- Date Issued: 2013
Enabling social learning as a response to environmental issues through teaching of localised curriculum in Zambian schools
- Authors: Sinyama, Imakando
- Date: 2012
- Subjects: Social learning -- Zambia -- Keembe (Central Province) Environmental education -- Zambia -- Keembe (Central Province) Environmental education -- Study and teaching -- Zambia -- Keembe (Central Province) Sustainable development -- Study and teaching -- Zambia -- Keembe (Central Province) Curriculum change -- Zambia -- Keembe (Central Province) Educational evaluation -- Zambia -- Keembe (Central Province)
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1508 , http://hdl.handle.net/10962/d1003390
- Description: Schools are traditionally established as the main meeting platforms for awareness, education, training and capacity building in the local communities, and as such, are highly regarded and respected. They are situated and integrated in nearly all local communities. They are thus perfectly suited to reach, draw on and provide capacity building to the communities. Zambia recently introduced a new curriculum aspect named localised curriculum, which makes up 20% of the curriculum. This curriculum area encourages schools to address issues of sustainable development that are locally relevant through this curriculum component, but it is not clear what kind of learning emerges from this curriculum aspect. The study looked at the shift in pedagogical discourse since the introduction of the localised curriculum. Using case study methodology and observation of a number of classroom activities in the Keemba District near Monze in Zambia, I observed social learning interactions taking place in the implementation of the localised curriculum. In particular, I was interested in how the different aspects of the localised curriculum enabled social learning, at different levels. What is important in this research is that it focused not so much on what people should know, or be able to do, but rather, drawing on some of the questions raised by Wals (2007), I considered questions of how people learn, and how social learning emerges in school-community interactions in the localised curriculum. The main research question was to investigate: How does localised curriculum enable social learning in response to environmental issues in Zambian schools? This research drew on a number of associated research projects that were carried out in southern Africa and beyond. In his research, Namafe (2008) states that he saw a great need to institutionalise increased participation of Zambian Basic Schools and their local communities in sustainable development of the country in order to alleviate poverty and achieve equitable development. Hogan (2008, p. 122 ) researching in a different context, argues that contextualisation of the curriculum allowed for indigenous knowledge to come in to the classroom, stating that ‘Weakening of the frames provided the opportunity of closer relationships to give space for knowledge other than teacher selected knowledge or book knowledge to enter the classroom.’ In this study I found that: - Teaching localised curriculum allowed for contextualisation and integration of environment and natural resource management issues - Localising the curriculum contributed to curriculum relevancy: teaching localised curriculum helped learners, teachers and community to develop concern for quality of life and contributed to an understanding of sustainable development - Localised curriculum allowed for frame awareness, frame deconstruction and reframing to take place: this allowed teachers to use methods which promoted active pupil participation and interaction, encouraging learners to be reflexive thinkers rather than just using rote memory - Participation of teachers, community and learners in the implementation of the localised curriculum: The involvement of community members to teach topics of the localised curriculum was useful and articulated processes of inter–epistemological dialogue between traditional or every day and scientific or institutional knowledge - The localised curriculum implementation involved various roles and was influenced by various factors. Of key interest to this study was the fact that neither parents, learners nor teachers saw the localised curriculum as an opportunity for problem solving, but rather emphasised the learning of practical life skills relevant to the community. This differed from the curriculum manuals, and reduced the environmental education potential and also social learning opportunities.
- Full Text:
- Date Issued: 2012
- Authors: Sinyama, Imakando
- Date: 2012
- Subjects: Social learning -- Zambia -- Keembe (Central Province) Environmental education -- Zambia -- Keembe (Central Province) Environmental education -- Study and teaching -- Zambia -- Keembe (Central Province) Sustainable development -- Study and teaching -- Zambia -- Keembe (Central Province) Curriculum change -- Zambia -- Keembe (Central Province) Educational evaluation -- Zambia -- Keembe (Central Province)
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1508 , http://hdl.handle.net/10962/d1003390
- Description: Schools are traditionally established as the main meeting platforms for awareness, education, training and capacity building in the local communities, and as such, are highly regarded and respected. They are situated and integrated in nearly all local communities. They are thus perfectly suited to reach, draw on and provide capacity building to the communities. Zambia recently introduced a new curriculum aspect named localised curriculum, which makes up 20% of the curriculum. This curriculum area encourages schools to address issues of sustainable development that are locally relevant through this curriculum component, but it is not clear what kind of learning emerges from this curriculum aspect. The study looked at the shift in pedagogical discourse since the introduction of the localised curriculum. Using case study methodology and observation of a number of classroom activities in the Keemba District near Monze in Zambia, I observed social learning interactions taking place in the implementation of the localised curriculum. In particular, I was interested in how the different aspects of the localised curriculum enabled social learning, at different levels. What is important in this research is that it focused not so much on what people should know, or be able to do, but rather, drawing on some of the questions raised by Wals (2007), I considered questions of how people learn, and how social learning emerges in school-community interactions in the localised curriculum. The main research question was to investigate: How does localised curriculum enable social learning in response to environmental issues in Zambian schools? This research drew on a number of associated research projects that were carried out in southern Africa and beyond. In his research, Namafe (2008) states that he saw a great need to institutionalise increased participation of Zambian Basic Schools and their local communities in sustainable development of the country in order to alleviate poverty and achieve equitable development. Hogan (2008, p. 122 ) researching in a different context, argues that contextualisation of the curriculum allowed for indigenous knowledge to come in to the classroom, stating that ‘Weakening of the frames provided the opportunity of closer relationships to give space for knowledge other than teacher selected knowledge or book knowledge to enter the classroom.’ In this study I found that: - Teaching localised curriculum allowed for contextualisation and integration of environment and natural resource management issues - Localising the curriculum contributed to curriculum relevancy: teaching localised curriculum helped learners, teachers and community to develop concern for quality of life and contributed to an understanding of sustainable development - Localised curriculum allowed for frame awareness, frame deconstruction and reframing to take place: this allowed teachers to use methods which promoted active pupil participation and interaction, encouraging learners to be reflexive thinkers rather than just using rote memory - Participation of teachers, community and learners in the implementation of the localised curriculum: The involvement of community members to teach topics of the localised curriculum was useful and articulated processes of inter–epistemological dialogue between traditional or every day and scientific or institutional knowledge - The localised curriculum implementation involved various roles and was influenced by various factors. Of key interest to this study was the fact that neither parents, learners nor teachers saw the localised curriculum as an opportunity for problem solving, but rather emphasised the learning of practical life skills relevant to the community. This differed from the curriculum manuals, and reduced the environmental education potential and also social learning opportunities.
- Full Text:
- Date Issued: 2012
Curating the reviled, beloved and quotidian: a retrospective of Vladimir Tretchikoff
- Authors: Lamprecht, Andrew Paul
- Date: 2011
- Subjects: Tretchikoff, Vladimir -- Criticism and interpretation Painters -- South Africa -- Criticism and interpretation Curatorship -- South Africa -- Art Kitsch
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2407 , http://hdl.handle.net/10962/d1002203
- Description: This thesis aims to contextualise my curation of 'Tretchikoff: The People's Painter' at the Iziko South African National Gallery by outlining the process by which I came to embark on this project and to examine the concepts of mass art and kitsch in relation to the painter. Mass art, in Noel Carroll's explication of the term, is art that utilises industrial processes of replication. Carroll argues that this leads to specific formal and structural tendencies in this art which have much in common with the pejorative concept of kitsch, or art that is lacking in taste or effuses excessive emotion. The latter term was and continues to be applied to Tretchikoff. Although some have attempted to 'reclaim' the word as a positive concept the negative associations that link this term to Tretchikoff are strong. Interrogating these concepts led me to decide to curate TretchikofPs retrospective by focusing on his painting and not including the prints for which he was so well known. Awareness of the complex associations and 'received knowledge' that his prints engender has influenced several curatorial decisions that I have taken. I consider the intellectual underpinnings of my curatorial strategy and argue for an 'open' exhibition which gives the viewer the opportunity to assess his work and legacy in an objective manner, free from as much curatorial mediation and didacticsm as possible. There are no answers to be offered in my curation of Tretchikxiff the People's Painter, rather I have aimed to set up dialogues, discussions, confrontations and challenges; I have offered simple relationships rather than complex juxtapositions I have aimed to position the artwork as the centre of the engagement relative to the viewer.
- Full Text:
- Date Issued: 2011
- Authors: Lamprecht, Andrew Paul
- Date: 2011
- Subjects: Tretchikoff, Vladimir -- Criticism and interpretation Painters -- South Africa -- Criticism and interpretation Curatorship -- South Africa -- Art Kitsch
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2407 , http://hdl.handle.net/10962/d1002203
- Description: This thesis aims to contextualise my curation of 'Tretchikoff: The People's Painter' at the Iziko South African National Gallery by outlining the process by which I came to embark on this project and to examine the concepts of mass art and kitsch in relation to the painter. Mass art, in Noel Carroll's explication of the term, is art that utilises industrial processes of replication. Carroll argues that this leads to specific formal and structural tendencies in this art which have much in common with the pejorative concept of kitsch, or art that is lacking in taste or effuses excessive emotion. The latter term was and continues to be applied to Tretchikoff. Although some have attempted to 'reclaim' the word as a positive concept the negative associations that link this term to Tretchikoff are strong. Interrogating these concepts led me to decide to curate TretchikofPs retrospective by focusing on his painting and not including the prints for which he was so well known. Awareness of the complex associations and 'received knowledge' that his prints engender has influenced several curatorial decisions that I have taken. I consider the intellectual underpinnings of my curatorial strategy and argue for an 'open' exhibition which gives the viewer the opportunity to assess his work and legacy in an objective manner, free from as much curatorial mediation and didacticsm as possible. There are no answers to be offered in my curation of Tretchikxiff the People's Painter, rather I have aimed to set up dialogues, discussions, confrontations and challenges; I have offered simple relationships rather than complex juxtapositions I have aimed to position the artwork as the centre of the engagement relative to the viewer.
- Full Text:
- Date Issued: 2011