Molecular characterization of streptococcus agalactiae isolated from pregnant women in the Eastern Cape, South Africa and Windhoek, Namibia and antibacterial activities of some medicinal plant extracts on the isolates
- Authors: Mukesi, Munyaradzi
- Date: 2018
- Subjects: Streptococcus Medicinal plants Pregnant women
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/13034 , vital:39437
- Description: Streptococcus agalactiae (S. agalactiae) also known as group B Streptococcus (GBS) is one of the leading causes of bacterial morbidity and mortality among neonates worldwide. It is the cause of invasive Early Onset Disease (EOD), which occurs in the first 7 days of life and characterised by sepsis, pneumonia and meningitis and Late Onset Disease (LOD) occurring between 7 and 89 days of life. Late onset disease is characterised by meningitis and long term neurological sequelae such as cerebral palsy, hearing impairment and cognitive challenges. S. agalactiae does not only infect neonates, it also infects the elderly, immunocompromised individuals and pregnant and non-pregnant women, causing invasive disease. In the world, 10-40 percent of healthy women are rectally or vaginally colonised with GBS and they face the risk of passing it to their babies during the process of childbirth. During parturition, a GBS colonized pregnant woman transfers the bacterium to her new-born as the baby passes through the ruptured membrane, thus infecting the child. However, GBS has been reported to be transferred even without rupture of membranes. Once it infects the membranes, it is transferred into the amniotic fluid and subsequently infects the baby. It can be aspirated into the lungs causing pneumonia or it can infect the blood stream and disseminated round the body causing septicaemia, meningitis and other infections. Once in the neonate’s body, the bacteria is able to evade the immune system as the host immune system is not yet fully developed. Bacterial evasion of the immune system is enhanced by its various virulence factors which are deployed to help it escape the immune system. These include the polysaccharide capsule, haemolysin and the release of complement inactivating factors such C5a peptidase. The World Health Organisation (WHO) (2010) recommends universal screening of pregnant women to identify those colonised and who are at risk of passing the bacterium to their babies during birth. WHO also recommends identification of at risk women and providing Intrapartum Antibiotic Prophylaxis (IAP) using penicillin. However, problems arise in penicillin allergic women and while alternatives for IAP include erythromycin and clindamycin, there is increasing resistance to these drugs thereby limiting therapeutic options. Antimicrobial susceptibility testing is also not always possible in most resource constrained countries due to poor infrastructure, limited access to health care and the logistical problems in implementing the WHO guidelines. Alternative therapeutic options to GBS infection include developing new and potent antibiotics, development of a vaccine, use of medicinal plants and the use of bacteriophage therapy. While these look like better alternatives there is massive scientific work to be carried out to ensure proper characterisation and efficiency of such alternatives. This process should be followed by in vitro diagnostic testing, experiments with animal models and clinical trials. The problems encountered during vaccine development to curtail GBS infection are compounded by the multiplicity of S. agalactiae capsular types which vary in different geographic locations. Medicinal plants are a cheap and convenient option since they are widely used in communities but the phytochemical components of the plants have to be identified and subjected to in vitro testing to evaluate their therapeutic efficacy as antimicrobial agents. This study therefore sought to isolate GBS from pregnant women between 35 and 37 weeks gestation in Windhoek (Namibia) and the Eastern Cape (South Africa), to determine the prevalence of GBS colonisation in the vagina and rectum of the pregnant women, characterise the isolates by molecular techniques, determine the antimicrobial resistance profiles and genes of the isolates and explore the efficacies of medicinal plant extracts as possible candidates for therapeutic options.
- Full Text:
- Authors: Mukesi, Munyaradzi
- Date: 2018
- Subjects: Streptococcus Medicinal plants Pregnant women
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/13034 , vital:39437
- Description: Streptococcus agalactiae (S. agalactiae) also known as group B Streptococcus (GBS) is one of the leading causes of bacterial morbidity and mortality among neonates worldwide. It is the cause of invasive Early Onset Disease (EOD), which occurs in the first 7 days of life and characterised by sepsis, pneumonia and meningitis and Late Onset Disease (LOD) occurring between 7 and 89 days of life. Late onset disease is characterised by meningitis and long term neurological sequelae such as cerebral palsy, hearing impairment and cognitive challenges. S. agalactiae does not only infect neonates, it also infects the elderly, immunocompromised individuals and pregnant and non-pregnant women, causing invasive disease. In the world, 10-40 percent of healthy women are rectally or vaginally colonised with GBS and they face the risk of passing it to their babies during the process of childbirth. During parturition, a GBS colonized pregnant woman transfers the bacterium to her new-born as the baby passes through the ruptured membrane, thus infecting the child. However, GBS has been reported to be transferred even without rupture of membranes. Once it infects the membranes, it is transferred into the amniotic fluid and subsequently infects the baby. It can be aspirated into the lungs causing pneumonia or it can infect the blood stream and disseminated round the body causing septicaemia, meningitis and other infections. Once in the neonate’s body, the bacteria is able to evade the immune system as the host immune system is not yet fully developed. Bacterial evasion of the immune system is enhanced by its various virulence factors which are deployed to help it escape the immune system. These include the polysaccharide capsule, haemolysin and the release of complement inactivating factors such C5a peptidase. The World Health Organisation (WHO) (2010) recommends universal screening of pregnant women to identify those colonised and who are at risk of passing the bacterium to their babies during birth. WHO also recommends identification of at risk women and providing Intrapartum Antibiotic Prophylaxis (IAP) using penicillin. However, problems arise in penicillin allergic women and while alternatives for IAP include erythromycin and clindamycin, there is increasing resistance to these drugs thereby limiting therapeutic options. Antimicrobial susceptibility testing is also not always possible in most resource constrained countries due to poor infrastructure, limited access to health care and the logistical problems in implementing the WHO guidelines. Alternative therapeutic options to GBS infection include developing new and potent antibiotics, development of a vaccine, use of medicinal plants and the use of bacteriophage therapy. While these look like better alternatives there is massive scientific work to be carried out to ensure proper characterisation and efficiency of such alternatives. This process should be followed by in vitro diagnostic testing, experiments with animal models and clinical trials. The problems encountered during vaccine development to curtail GBS infection are compounded by the multiplicity of S. agalactiae capsular types which vary in different geographic locations. Medicinal plants are a cheap and convenient option since they are widely used in communities but the phytochemical components of the plants have to be identified and subjected to in vitro testing to evaluate their therapeutic efficacy as antimicrobial agents. This study therefore sought to isolate GBS from pregnant women between 35 and 37 weeks gestation in Windhoek (Namibia) and the Eastern Cape (South Africa), to determine the prevalence of GBS colonisation in the vagina and rectum of the pregnant women, characterise the isolates by molecular techniques, determine the antimicrobial resistance profiles and genes of the isolates and explore the efficacies of medicinal plant extracts as possible candidates for therapeutic options.
- Full Text:
A strategic framework for managing and implementation of the intergovernmental relations policy in selected Eastern Cape municipalities
- Authors: Shasha, Zamuxolo
- Date: 2017
- Subjects: Intergovernmental fiscal relations -- South Africa Local government -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/8353 , vital:32310
- Description: It is of paramount importance to highlight that the South African government is established in terms of the Constitution of the Republic of South Africa of 1996. Whilst the government of South Africa is one, it consists of three spheres namely; national, provincial and local. These spheres of government are naturally distinctive, interdependent and interrelated. This is expressed in terms of section 41(1) of the Constitution, which requires that there should be co-operation, mutual trust and good faith amongst these three spheres of government. This form of a relationship compels different spheres to inform and consult one another on matters of common interest, co-ordinate their legislation, and adhere to agreed procedures in accordance with the provisions of the constitution which is the supreme law of the Republic. The study sort to find a strategic framework for managing and implementation of the Intergovernmental Relations Policy in Selected Eastern Cape Municipalities. A purposive sampling technique was used to identify the sample elements. The sample was composed of 160 participants and a semi-structured questionnaire was administered to the participants to gather information pertaining the research problem. A mixed research method was used to analyse the data gathered. The sampled respondents were municipal and government employees from various departments who have knowledge of the IGR policy. The study findings pointed out that the current framework on intergovernmental relations was ineffective in the Eastern Cape municipalities that were surveyed. Respondents pointed to a number of shortfalls in the implementation of the intergovernmental relations, which made it ineffective in improving how these municipalities operated and rendered service delivery. A number of factors inhibiting the effectiveness of the intergovernmental relations included lack of communication, poor coordination, lack of clear strategy, poor budgets amongst other factors. Based on the findings of the study, the researcher developed a strategic framework that could be adopted by municipalities in the Eastern Cape. The functionality of this framework would be influenced by the corrective measures taken by the municipalities in addressing the underlying problems of the current intergovernmental relations, as identified by the respondents.
- Full Text: false
- Authors: Shasha, Zamuxolo
- Date: 2017
- Subjects: Intergovernmental fiscal relations -- South Africa Local government -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/8353 , vital:32310
- Description: It is of paramount importance to highlight that the South African government is established in terms of the Constitution of the Republic of South Africa of 1996. Whilst the government of South Africa is one, it consists of three spheres namely; national, provincial and local. These spheres of government are naturally distinctive, interdependent and interrelated. This is expressed in terms of section 41(1) of the Constitution, which requires that there should be co-operation, mutual trust and good faith amongst these three spheres of government. This form of a relationship compels different spheres to inform and consult one another on matters of common interest, co-ordinate their legislation, and adhere to agreed procedures in accordance with the provisions of the constitution which is the supreme law of the Republic. The study sort to find a strategic framework for managing and implementation of the Intergovernmental Relations Policy in Selected Eastern Cape Municipalities. A purposive sampling technique was used to identify the sample elements. The sample was composed of 160 participants and a semi-structured questionnaire was administered to the participants to gather information pertaining the research problem. A mixed research method was used to analyse the data gathered. The sampled respondents were municipal and government employees from various departments who have knowledge of the IGR policy. The study findings pointed out that the current framework on intergovernmental relations was ineffective in the Eastern Cape municipalities that were surveyed. Respondents pointed to a number of shortfalls in the implementation of the intergovernmental relations, which made it ineffective in improving how these municipalities operated and rendered service delivery. A number of factors inhibiting the effectiveness of the intergovernmental relations included lack of communication, poor coordination, lack of clear strategy, poor budgets amongst other factors. Based on the findings of the study, the researcher developed a strategic framework that could be adopted by municipalities in the Eastern Cape. The functionality of this framework would be influenced by the corrective measures taken by the municipalities in addressing the underlying problems of the current intergovernmental relations, as identified by the respondents.
- Full Text: false
Factor analysis for dtetermination of metabolic syndrome components of anthropometric data from Kinshasa hiterland of the Democractic Republic of Congo
- Authors: Nasila, John Sungwacha
- Date: 2017
- Subjects: Factor analysis Multivariate analysis
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/14032 , vital:39799
- Description: Factor analysis is a multivariate statistical approach commonly used in psychology, education, and more recently in the health-related professions. This thesis will attempt to provide novice and experienced researchers an application of two factor analysis methods which are; exploratory factor analysis (EFA) and Confirmatory Factor Analysis (CFA) to medical data. As Biostatistics knowledge continues to grow, it is timely that this thesis contributes immensely; firstly to the discipline of Biostatistics and secondly to Medicine both nationally and internationally. Factor analysis is an important tool that can be used in the development, refinement, and evaluation of tests, scales, and measures that can be used in education and in health-related professions such as medicine. This thesis is focused on applying Factor Analysis on medical data, specifically on data obtained from patients that suffer from Metabolic Syndrome and patients who don’t suffer from Metabolic Syndrome. Metabolic Syndrome (MS) is a constellation of components (factors) such as obesity, lipid-lipoprotein (fats) disorders, increase in glucose (sugar), hypertension (blood pressure), and inflammation/ hypercoagulability (clotting). MS and other risk factors; (smoking, physical inactivity, excessive alcohol intake, and inappropriate diet) determine high morbidity and mortality for the cardiovascular disease (CVD=heart attack, brain attack, peripheral vascular disease) or cardio-metabolic risk (CMR=type 2 diabetes, kidney disease, retinopathy). Obesity, CVD, and CMR are emerging as epidemic conditions worldwide. However, Africa is not paying priority to early detection, treatment, prevention and control of atherosclerotic diseases (MS, CMR) from valid and reliable data. The aim of this thesis was to examine anthropometry, glucose and blood pressure (non-lipid components of MS) as most valid, reliable, less time-consuming, less complex and less expensive procedure of identifying people at high risks of CVD and CMR. A further contribution of this thesis was its understanding of the economic implications of the burden of Metabolic Syndrome. Other burden factors have been identified and also discussed. The study has revealed that the presence of metabolic syndrome has contributed to an enormous economic burden by about 20percent of the total economic loss experienced by many countries. The prevalence has risen recently and elevated patients’ use of more health care resources, and face higher morbidity and mortality, resulting in an enormous economic burden. Some studies have shown healthcare costs to be as much as 20percent higher than those accrued by patients without the risk factors. Patients with the Metabolic Syndrome have been shown to have greater drug expenditures, more frequent hospitalizations, and higher utilization of outpatient and physician services. When considered alone, the individual risk factor components account for a substantial economic burden to patients, health plans, and society as a whole. Overall, this has had serious economic impacts on many countries. The diagnosis of Metabolic Syndrome as a condition may encourage appropriate management and thus help prevent disease progression and reduce the considerable economic impact. This study was a cross-sectional, comparative, and correlational survey conducted between January and April 2005, in Kinshasa Hinterland, DRC. Participants were black Bantu Africans. In this study, the researcher attempted to determine latent factors that could explain the variability in a large set of data collected on many individuals of mixed health statuses. The original population consisted of 9770 people of whom, only 977 (10percent) participated. Factor analysis and interpretation of the results were based on anthropometric parameters (body mass index or BMI and waist circumference or WC), blood pressure (BP), lipid (triglycerides)-lipoprotein (HDL-C) and glucose with different numbers and cutoffs of components of Metabolic Syndrome. A number of different statistical procedural methods have been employed to clearly scrutinize and bring out the information which is concealed in a variety of variables observed/collected on many human participants. A large portion of these approaches was based on multivariate statistical methods. The approach, in this case, was the application of Principal Component Analysis (PCA); a multivariate statistical approach used under Factor Analysis to reduce many variables into a few latent variables which are seen as capable of explaining the variability. The approach was effected under both conditions of presence and absence of metabolic risk. Other data settings were: within males, within females, in the rural and in urban communities.
- Full Text:
- Authors: Nasila, John Sungwacha
- Date: 2017
- Subjects: Factor analysis Multivariate analysis
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/14032 , vital:39799
- Description: Factor analysis is a multivariate statistical approach commonly used in psychology, education, and more recently in the health-related professions. This thesis will attempt to provide novice and experienced researchers an application of two factor analysis methods which are; exploratory factor analysis (EFA) and Confirmatory Factor Analysis (CFA) to medical data. As Biostatistics knowledge continues to grow, it is timely that this thesis contributes immensely; firstly to the discipline of Biostatistics and secondly to Medicine both nationally and internationally. Factor analysis is an important tool that can be used in the development, refinement, and evaluation of tests, scales, and measures that can be used in education and in health-related professions such as medicine. This thesis is focused on applying Factor Analysis on medical data, specifically on data obtained from patients that suffer from Metabolic Syndrome and patients who don’t suffer from Metabolic Syndrome. Metabolic Syndrome (MS) is a constellation of components (factors) such as obesity, lipid-lipoprotein (fats) disorders, increase in glucose (sugar), hypertension (blood pressure), and inflammation/ hypercoagulability (clotting). MS and other risk factors; (smoking, physical inactivity, excessive alcohol intake, and inappropriate diet) determine high morbidity and mortality for the cardiovascular disease (CVD=heart attack, brain attack, peripheral vascular disease) or cardio-metabolic risk (CMR=type 2 diabetes, kidney disease, retinopathy). Obesity, CVD, and CMR are emerging as epidemic conditions worldwide. However, Africa is not paying priority to early detection, treatment, prevention and control of atherosclerotic diseases (MS, CMR) from valid and reliable data. The aim of this thesis was to examine anthropometry, glucose and blood pressure (non-lipid components of MS) as most valid, reliable, less time-consuming, less complex and less expensive procedure of identifying people at high risks of CVD and CMR. A further contribution of this thesis was its understanding of the economic implications of the burden of Metabolic Syndrome. Other burden factors have been identified and also discussed. The study has revealed that the presence of metabolic syndrome has contributed to an enormous economic burden by about 20percent of the total economic loss experienced by many countries. The prevalence has risen recently and elevated patients’ use of more health care resources, and face higher morbidity and mortality, resulting in an enormous economic burden. Some studies have shown healthcare costs to be as much as 20percent higher than those accrued by patients without the risk factors. Patients with the Metabolic Syndrome have been shown to have greater drug expenditures, more frequent hospitalizations, and higher utilization of outpatient and physician services. When considered alone, the individual risk factor components account for a substantial economic burden to patients, health plans, and society as a whole. Overall, this has had serious economic impacts on many countries. The diagnosis of Metabolic Syndrome as a condition may encourage appropriate management and thus help prevent disease progression and reduce the considerable economic impact. This study was a cross-sectional, comparative, and correlational survey conducted between January and April 2005, in Kinshasa Hinterland, DRC. Participants were black Bantu Africans. In this study, the researcher attempted to determine latent factors that could explain the variability in a large set of data collected on many individuals of mixed health statuses. The original population consisted of 9770 people of whom, only 977 (10percent) participated. Factor analysis and interpretation of the results were based on anthropometric parameters (body mass index or BMI and waist circumference or WC), blood pressure (BP), lipid (triglycerides)-lipoprotein (HDL-C) and glucose with different numbers and cutoffs of components of Metabolic Syndrome. A number of different statistical procedural methods have been employed to clearly scrutinize and bring out the information which is concealed in a variety of variables observed/collected on many human participants. A large portion of these approaches was based on multivariate statistical methods. The approach, in this case, was the application of Principal Component Analysis (PCA); a multivariate statistical approach used under Factor Analysis to reduce many variables into a few latent variables which are seen as capable of explaining the variability. The approach was effected under both conditions of presence and absence of metabolic risk. Other data settings were: within males, within females, in the rural and in urban communities.
- Full Text:
Assessment of the implementation of the National Certificate (Vocational) plant production modules
- Langa, Phakama Perry Macmillan
- Authors: Langa, Phakama Perry Macmillan
- Date: 2016
- Subjects: Curriculum planning Technical education -- Curricula Vocational education -- Curricula
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2359 , vital:27778
- Description: From 2010, the South African vocational skills education is offered by the Department of Higher Education and Training (DHET) through the Technical Vocational Education and Training (TVET) colleges. TVET colleges need to be transformed in order to empower young learners with the skills required by the various sectors of the economy. The purpose of this study was to assess the implementation of the National Certificate (Vocational) Plant Production module in Training and Vocational Education and Training (TVET) Colleges. The sample for this study is concurrent triangulation whereby complementary methods of data sources were brought together to offset each other‘s weaknesses. The sample for this study consisted of participants from three TVET colleges: one deep rural, one semi-rural/semi-urban and one urban in terms of geographical location. A total of 18 participants were interviewed: 2 subject advisors engaged by the colleges, 1 lecturer from college A, 3 lecturers from college B, 2 lecturers from college C, 4 graduates from college B, 3 graduates from college C and 3 employers .Research design for this study has features of both a survey and a case study. The mixed-method approach was applied using document analysis, questionnaires and interviews for data collection. The researcher found out that there is a disparity between the Plant Production guidelines and their implementation and assessment. Among the main reasons for failure to implement the guidelines properly are poor or inadequate infrastructure for doing practical work, high rate of student absenteeism within the investigated categories, and the high drop-out rate at Levels 2–4. To minimize the challenges in offering the Plant Production module, the study recommends that since some colleges cannot afford purchasing large sizes of land to properly implement the Plant Production guidelines, the government and the DHET should link the Primary Agriculture training to the land reform program where students can be trained under the land reform program.
- Full Text:
- Authors: Langa, Phakama Perry Macmillan
- Date: 2016
- Subjects: Curriculum planning Technical education -- Curricula Vocational education -- Curricula
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2359 , vital:27778
- Description: From 2010, the South African vocational skills education is offered by the Department of Higher Education and Training (DHET) through the Technical Vocational Education and Training (TVET) colleges. TVET colleges need to be transformed in order to empower young learners with the skills required by the various sectors of the economy. The purpose of this study was to assess the implementation of the National Certificate (Vocational) Plant Production module in Training and Vocational Education and Training (TVET) Colleges. The sample for this study is concurrent triangulation whereby complementary methods of data sources were brought together to offset each other‘s weaknesses. The sample for this study consisted of participants from three TVET colleges: one deep rural, one semi-rural/semi-urban and one urban in terms of geographical location. A total of 18 participants were interviewed: 2 subject advisors engaged by the colleges, 1 lecturer from college A, 3 lecturers from college B, 2 lecturers from college C, 4 graduates from college B, 3 graduates from college C and 3 employers .Research design for this study has features of both a survey and a case study. The mixed-method approach was applied using document analysis, questionnaires and interviews for data collection. The researcher found out that there is a disparity between the Plant Production guidelines and their implementation and assessment. Among the main reasons for failure to implement the guidelines properly are poor or inadequate infrastructure for doing practical work, high rate of student absenteeism within the investigated categories, and the high drop-out rate at Levels 2–4. To minimize the challenges in offering the Plant Production module, the study recommends that since some colleges cannot afford purchasing large sizes of land to properly implement the Plant Production guidelines, the government and the DHET should link the Primary Agriculture training to the land reform program where students can be trained under the land reform program.
- Full Text:
Assessment of the implementation of the National Certificate (Vocational) plant production modules
- Langa, Phakama Perry Macmillan
- Authors: Langa, Phakama Perry Macmillan
- Date: 2016
- Subjects: Technical education -- Curricula Vocational education -- Curricula Curriculum planning
- Language: English
- Type: Thesis , Doctoral , Degree
- Identifier: http://hdl.handle.net/10353/5391 , vital:29229
- Description: This study investigates the implementation of Language in Education Policy (LiEP) in learning and teaching in grades six from two schools. It critically examines the teachers’ practices and experiences towards English as the language of learning and teaching (LoLT) at two different primary schools from the eMalahleni in the Lady Frere Education District in the Eastern Cape. The study is guided by the fact that most learners use their mother tongue (isiXhosa) in classroom as well as outside classroom contexts. Furthermore, some teachers use the translation method of teaching language as they code-switch to their home language when teaching content subjects as well as English. Despite this practice in class, learners are expected to answer their test and examination questions in English. Theoretically, this study is underpinned by the constructivist view of language learning (Gaserfeld, 2003) and English as an international language (Sivasubramaniam, 2011). On the basis of the ecological and the constructivist approaches to language learning, Sivasubramaniam (2011 p.53) views language as a creative instrument of meaning which ‘has the power to create meaning anew and afresh’ each time that someone uses it. The study makes use of the qualitative research method with a case study design that is placed within the interpretive paradigm. The data collected will be analysed through the use of critical discourse analysis. The findings from the study suggest some instrumental motivations to use English as LOLT which is informed by Language policy. Some of these motivations are: studying abroad, business with foreign investors and integrative motivations as the learner will be able to communicate with people from different countries. The study concludes that there is need for schools to stick to the English medium because this acts as an open door to the upward economic mobility among the previously disadvantaged. Based on this, it can be recommended that schools stick to English first additional language as their language of teaching and learning.
- Full Text:
- Authors: Langa, Phakama Perry Macmillan
- Date: 2016
- Subjects: Technical education -- Curricula Vocational education -- Curricula Curriculum planning
- Language: English
- Type: Thesis , Doctoral , Degree
- Identifier: http://hdl.handle.net/10353/5391 , vital:29229
- Description: This study investigates the implementation of Language in Education Policy (LiEP) in learning and teaching in grades six from two schools. It critically examines the teachers’ practices and experiences towards English as the language of learning and teaching (LoLT) at two different primary schools from the eMalahleni in the Lady Frere Education District in the Eastern Cape. The study is guided by the fact that most learners use their mother tongue (isiXhosa) in classroom as well as outside classroom contexts. Furthermore, some teachers use the translation method of teaching language as they code-switch to their home language when teaching content subjects as well as English. Despite this practice in class, learners are expected to answer their test and examination questions in English. Theoretically, this study is underpinned by the constructivist view of language learning (Gaserfeld, 2003) and English as an international language (Sivasubramaniam, 2011). On the basis of the ecological and the constructivist approaches to language learning, Sivasubramaniam (2011 p.53) views language as a creative instrument of meaning which ‘has the power to create meaning anew and afresh’ each time that someone uses it. The study makes use of the qualitative research method with a case study design that is placed within the interpretive paradigm. The data collected will be analysed through the use of critical discourse analysis. The findings from the study suggest some instrumental motivations to use English as LOLT which is informed by Language policy. Some of these motivations are: studying abroad, business with foreign investors and integrative motivations as the learner will be able to communicate with people from different countries. The study concludes that there is need for schools to stick to the English medium because this acts as an open door to the upward economic mobility among the previously disadvantaged. Based on this, it can be recommended that schools stick to English first additional language as their language of teaching and learning.
- Full Text:
Examining the nature and extent to which learners with special educational needs are included in regular schools: the case of four primary schools in Cape Town, South Africa
- Authors: Shadaya, Girlie
- Date: 2016
- Subjects: Special education Inclusive education -- South Africa -- Cape Town Children with disabilities -- Education -- South Africa -- Cape Town
- Language: English
- Type: Thesis , Doctoral , Degree
- Identifier: http://hdl.handle.net/10353/5346 , vital:29214
- Description: The study is premised on the assumptions that learners with special educational needs are not fully included in regular schools and that perceptions of teachers influence their behaviour toward and acceptance of learners with special educational needs in regular classes. In light of this, the aim of the current study was to examine the nature and extent to which learners with special educational needs are included in regular schools with the ultimate aim of assisting learners with special educational needs to be fully catered for by schools and teachers. The researcher opted for the mixed method approach which is embedded in the post positivist research paradigm. The mixed method approach makes use of quantitative and qualitative methods of data collection, presentation and analysis. Data were generated from a sample of 60 teachers and 4 principals from 4 regular primary schools mainly through questionnaires. Data were also generated from interviews, observation and documents. These data from interviews, observation and documents were used to buttress results from the questionnaires. The findings of this present study showed that many schools are now moving towards inclusivity. There is a relative prevalence of learners with disability in schools. The study also established that the inclusion of learners with special educational needs in regular schools was faced with a number of problems. There were inadequate professionally-trained teachers in schools. Shortage of classrooms, large class sizes, equipment and materials affected the quality of access to education for learners with special educational needs. Although there was significant support at school level, it emerged that there was inadequate quality in-service training programmes for teachers conducted by district officials. Overall, the findings of the study have confirmed the assumptions of the study. For learners with special educational needs to be fully included in regular schools, the study would recommend that the government improve the quality of teachers through in-service training programmes. Moreover, schools must be adequately resourced and government should commit itself to the alleviation of large class sizes. The study further revealed that, gaps still exist in the inclusion of learners with special educational needs between the intended and the actual practice. The study, therefore, recommends that research be conducted with the possibility of establishing strategies for the inclusion of learners with special educational needs in regular schools. This might improve the actual practice of including learners with iii special educational needs in regular schools. In turn, learners with special educational needs can be said to have equal access to education.
- Full Text:
- Authors: Shadaya, Girlie
- Date: 2016
- Subjects: Special education Inclusive education -- South Africa -- Cape Town Children with disabilities -- Education -- South Africa -- Cape Town
- Language: English
- Type: Thesis , Doctoral , Degree
- Identifier: http://hdl.handle.net/10353/5346 , vital:29214
- Description: The study is premised on the assumptions that learners with special educational needs are not fully included in regular schools and that perceptions of teachers influence their behaviour toward and acceptance of learners with special educational needs in regular classes. In light of this, the aim of the current study was to examine the nature and extent to which learners with special educational needs are included in regular schools with the ultimate aim of assisting learners with special educational needs to be fully catered for by schools and teachers. The researcher opted for the mixed method approach which is embedded in the post positivist research paradigm. The mixed method approach makes use of quantitative and qualitative methods of data collection, presentation and analysis. Data were generated from a sample of 60 teachers and 4 principals from 4 regular primary schools mainly through questionnaires. Data were also generated from interviews, observation and documents. These data from interviews, observation and documents were used to buttress results from the questionnaires. The findings of this present study showed that many schools are now moving towards inclusivity. There is a relative prevalence of learners with disability in schools. The study also established that the inclusion of learners with special educational needs in regular schools was faced with a number of problems. There were inadequate professionally-trained teachers in schools. Shortage of classrooms, large class sizes, equipment and materials affected the quality of access to education for learners with special educational needs. Although there was significant support at school level, it emerged that there was inadequate quality in-service training programmes for teachers conducted by district officials. Overall, the findings of the study have confirmed the assumptions of the study. For learners with special educational needs to be fully included in regular schools, the study would recommend that the government improve the quality of teachers through in-service training programmes. Moreover, schools must be adequately resourced and government should commit itself to the alleviation of large class sizes. The study further revealed that, gaps still exist in the inclusion of learners with special educational needs between the intended and the actual practice. The study, therefore, recommends that research be conducted with the possibility of establishing strategies for the inclusion of learners with special educational needs in regular schools. This might improve the actual practice of including learners with iii special educational needs in regular schools. In turn, learners with special educational needs can be said to have equal access to education.
- Full Text:
Examining the nature and extent to which learners with special educational needs are included in regular schools: the case of four primary schools in Cape Town, South Africa
- Authors: Shadaya, Girlie
- Date: 2016
- Subjects: Special education -- South Africa -- Cape Town Inclusive education -- South Africa -- Cape Town Children with disabilities -- Education -- South Africa -- Cape Town
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2336 , vital:27754
- Description: The study is premised on the assumptions that learners with special educational needs are not fully included in regular schools and that perceptions of teachers influence their behaviour toward and acceptance of learners with special educational needs in regular classes. In light of this, the aim of the current study was to examine the nature and extent to which learners with special educational needs are included in regular schools with the ultimate aim of assisting learners with special educational needs to be fully catered for by schools and teachers. The researcher opted for the mixed method approach which is embedded in the post positivist research paradigm. The mixed method approach makes use of quantitative and qualitative methods of data collection, presentation and analysis. Data were generated from a sample of 60 teachers and 4 principals from 4 regular primary schools mainly through questionnaires. Data were also generated from interviews, observation and documents. These data from interviews, observation and documents were used to buttress results from the questionnaires. The findings of this present study showed that many schools are now moving towards inclusivity. There is a relative prevalence of learners with disability in schools. The study also established that the inclusion of learners with special educational needs in regular schools was faced with a number of problems. There were inadequate professionally-trained teachers in schools. Shortage of classrooms, large class sizes, equipment and materials affected the quality of access to education for learners with special educational needs. Although there was significant support at school level, it emerged that there was inadequate quality in-service training programmes for teachers conducted by district officials. Overall, the findings of the study have confirmed the assumptions of the study. For learners with special educational needs to be fully included in regular schools, the study would recommend that the government improve the quality of teachers through in-service training programmes. Moreover, schools must be adequately resourced and government should commit itself to the alleviation of large class sizes. The study further revealed that, gaps still exist in the inclusion of learners with special educational needs between the intended and the actual practice. The study, therefore, recommends that research be conducted with the possibility of establishing strategies for the inclusion of learners with special educational needs in regular schools. This might improve the actual practice of including learners with special educational needs in regular schools. In turn, learners with special educational needs can be said to have equal access to education.
- Full Text:
- Authors: Shadaya, Girlie
- Date: 2016
- Subjects: Special education -- South Africa -- Cape Town Inclusive education -- South Africa -- Cape Town Children with disabilities -- Education -- South Africa -- Cape Town
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2336 , vital:27754
- Description: The study is premised on the assumptions that learners with special educational needs are not fully included in regular schools and that perceptions of teachers influence their behaviour toward and acceptance of learners with special educational needs in regular classes. In light of this, the aim of the current study was to examine the nature and extent to which learners with special educational needs are included in regular schools with the ultimate aim of assisting learners with special educational needs to be fully catered for by schools and teachers. The researcher opted for the mixed method approach which is embedded in the post positivist research paradigm. The mixed method approach makes use of quantitative and qualitative methods of data collection, presentation and analysis. Data were generated from a sample of 60 teachers and 4 principals from 4 regular primary schools mainly through questionnaires. Data were also generated from interviews, observation and documents. These data from interviews, observation and documents were used to buttress results from the questionnaires. The findings of this present study showed that many schools are now moving towards inclusivity. There is a relative prevalence of learners with disability in schools. The study also established that the inclusion of learners with special educational needs in regular schools was faced with a number of problems. There were inadequate professionally-trained teachers in schools. Shortage of classrooms, large class sizes, equipment and materials affected the quality of access to education for learners with special educational needs. Although there was significant support at school level, it emerged that there was inadequate quality in-service training programmes for teachers conducted by district officials. Overall, the findings of the study have confirmed the assumptions of the study. For learners with special educational needs to be fully included in regular schools, the study would recommend that the government improve the quality of teachers through in-service training programmes. Moreover, schools must be adequately resourced and government should commit itself to the alleviation of large class sizes. The study further revealed that, gaps still exist in the inclusion of learners with special educational needs between the intended and the actual practice. The study, therefore, recommends that research be conducted with the possibility of establishing strategies for the inclusion of learners with special educational needs in regular schools. This might improve the actual practice of including learners with special educational needs in regular schools. In turn, learners with special educational needs can be said to have equal access to education.
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The enforcement of the right of access to adequate housing in South Africa: a lesson for Lesotho
- Authors: Pule, Sesinyi Edwin
- Date: 2014
- Subjects: Housing -- Law and legislation -- South Africa , Housing -- Law and legislation -- Lesotho
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11122 , http://hdl.handle.net/10353/d1016249 , Housing -- Law and legislation -- South Africa , Housing -- Law and legislation -- Lesotho
- Description: South Africa is one of the countries with a very horrifying history. However, in the dawn of democratic governance, a worldly admirable constitution was brought into picture. The 1993 and 1996 South African Constitutions entrenched an elaborate Bill of Rights with provisions empowering courts to grant “appropriate relief and to make “just and equitable” orders. Happily, the Bill of Rights included justiciable and enforceable socio-economic rights. Amongst them, there is a right of access to adequate housing, for which this work is about. South Africa is viewed as a country with developed jurisprudence in the enforcement of socio-economic rights, hence it has been used as a lesson for Lesotho. Lesotho is still drowning in deep blue seas on enforcement of socio-economic rights either because the constitution itself hinders the progress thereon or because the parliament is unwilling to commit execute to the obligations found in the socio-economic rights filed. This work scrutinizes many jurisdictions and legal systems with a view to draw lively examples that may be followed by Lesotho courts towards enforcing housing rights. Indian and South African jurisprudences epitomize this notion.
- Full Text:
- Authors: Pule, Sesinyi Edwin
- Date: 2014
- Subjects: Housing -- Law and legislation -- South Africa , Housing -- Law and legislation -- Lesotho
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11122 , http://hdl.handle.net/10353/d1016249 , Housing -- Law and legislation -- South Africa , Housing -- Law and legislation -- Lesotho
- Description: South Africa is one of the countries with a very horrifying history. However, in the dawn of democratic governance, a worldly admirable constitution was brought into picture. The 1993 and 1996 South African Constitutions entrenched an elaborate Bill of Rights with provisions empowering courts to grant “appropriate relief and to make “just and equitable” orders. Happily, the Bill of Rights included justiciable and enforceable socio-economic rights. Amongst them, there is a right of access to adequate housing, for which this work is about. South Africa is viewed as a country with developed jurisprudence in the enforcement of socio-economic rights, hence it has been used as a lesson for Lesotho. Lesotho is still drowning in deep blue seas on enforcement of socio-economic rights either because the constitution itself hinders the progress thereon or because the parliament is unwilling to commit execute to the obligations found in the socio-economic rights filed. This work scrutinizes many jurisdictions and legal systems with a view to draw lively examples that may be followed by Lesotho courts towards enforcing housing rights. Indian and South African jurisprudences epitomize this notion.
- Full Text:
Prevalence of Listeria pathogens in effluents of some wastewater treatment facilities in the Eastern Cape Province of South Africa
- Odjadjare, Emmanuel Erufuare Onogwuwhenya
- Authors: Odjadjare, Emmanuel Erufuare Onogwuwhenya
- Date: 2010
- Subjects: Listeria -- South Africa -- Eastern Cape Sewage -- Purification -- South Africa -- Eastern Cape Water -- Pollution -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/7826 , vital:30747
- Description: astewater discharges may contain health compromising pathogens and carcinogenic and/or chemical substances that could compromise the public health and impact negatively on the environment. The present study was conducted between August 2007 and July 2008 to evaluate the Listeria abundance (as free-living and plankton associated species) and physicochemical qualities of the final effluents of three wastewater treatment facilities in the Eastern Cape Province of South Africa selected to represent typical urban, peri-urban and rural communities and the impact of the discharged final effluents on their respective receiving watershed, as well as to elucidated the in vitro antibiotic susceptibilities and resistance genes profile of Listeria species isolated from the final effluents. The suitability of the secondary effluent of the urban treatment facility (as a case study) for use in agriculture and aquaculture with reference to recommended standards was also determined. Wastewater samples were collected from the raw sewage, secondary effluent, final treated effluent, discharge point, 500 m upstream discharge point, and 500 m downstream discharge point from all three locations on a monthly basis throughout the study period. Listeria abundance in the final effluents and the receiving watersheds varied between 2.9× 100 and 3.52 × 105cfu/ml across the sampled locations. Free-living listerial density across the sampled locations ranged between 0 and 3.2 × 103cfu/ml while counts of Listeria species attached to large (180 μm) planktons varied from 0 to 1.58 × 105 cfu/ml and those of the 60 and 20 μm categories were in the range of 0 to 1.32 × 103 cfu/ml and 0 to 2.82 × 105 cfu/ml respectively. Listeria abundance did not vary significantly with location and season; there was however, significant (P < 0.05; P < 0.01) variance in Listeria abundance with plankton sizes across the locations. Free-living Listeria species were more abundant in the rural and urban xii communities than plankton attached Listeria species; whereas the reverse was the case in the peri-urban community.
- Full Text:
- Authors: Odjadjare, Emmanuel Erufuare Onogwuwhenya
- Date: 2010
- Subjects: Listeria -- South Africa -- Eastern Cape Sewage -- Purification -- South Africa -- Eastern Cape Water -- Pollution -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/7826 , vital:30747
- Description: astewater discharges may contain health compromising pathogens and carcinogenic and/or chemical substances that could compromise the public health and impact negatively on the environment. The present study was conducted between August 2007 and July 2008 to evaluate the Listeria abundance (as free-living and plankton associated species) and physicochemical qualities of the final effluents of three wastewater treatment facilities in the Eastern Cape Province of South Africa selected to represent typical urban, peri-urban and rural communities and the impact of the discharged final effluents on their respective receiving watershed, as well as to elucidated the in vitro antibiotic susceptibilities and resistance genes profile of Listeria species isolated from the final effluents. The suitability of the secondary effluent of the urban treatment facility (as a case study) for use in agriculture and aquaculture with reference to recommended standards was also determined. Wastewater samples were collected from the raw sewage, secondary effluent, final treated effluent, discharge point, 500 m upstream discharge point, and 500 m downstream discharge point from all three locations on a monthly basis throughout the study period. Listeria abundance in the final effluents and the receiving watersheds varied between 2.9× 100 and 3.52 × 105cfu/ml across the sampled locations. Free-living listerial density across the sampled locations ranged between 0 and 3.2 × 103cfu/ml while counts of Listeria species attached to large (180 μm) planktons varied from 0 to 1.58 × 105 cfu/ml and those of the 60 and 20 μm categories were in the range of 0 to 1.32 × 103 cfu/ml and 0 to 2.82 × 105 cfu/ml respectively. Listeria abundance did not vary significantly with location and season; there was however, significant (P < 0.05; P < 0.01) variance in Listeria abundance with plankton sizes across the locations. Free-living Listeria species were more abundant in the rural and urban xii communities than plankton attached Listeria species; whereas the reverse was the case in the peri-urban community.
- Full Text:
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