An exploration of the principle of Dance Movement Therapy in water resource management research practice:
- Authors: Copteros, Athina
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142016 , vital:38024 , ISBN PECS Conference: Social-ecological dynamics in the Anthropocene, Spier Estate, Cape Town, 2-5 November , http://www.pecs-science.org/research/news/news/2015pecsconferencesocialecologicaldynamicsintheanthropocene.5.40768cbb14b32a0480b694.html
- Description: An exploration of the principle of Dance Movement Therapy in water resource management research practice
- Full Text:
- Date Issued: 2015
Antjie Krog and the post-apartheid public sphere: Speaking poetry to power
- Authors: Garman, Anthea
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/159913 , vital:40355 , ISBN 978-1869142933
- Description: Antjie Krog has been known in Afrikaans literary circles and the media for decades because of her poetry and her strong political convictions. Often known simply as 'Antjie,' she is also affectionately called 'our beloved poet' and our 'Joan of Arc' by Afrikaans commentators. It was through her work on the Truth and Reconciliation Commission as an SABC radio journalist and her subsequent book, Country of My Skull, that Antjie Krog then became known to English-speakers in South Africa and across the world. Her work catapulted her particular brand of poetics and politics, honed over many years of her opposition to apartheid, into the South African public sphere at a time when the country was not only looking for a humane and just resolution after the apartheid era, but was also establishing itself as a new democracy.
- Full Text:
- Date Issued: 2015
Being at Home: Race, Institutional Culture and Transformation at South African Higher Education Institutions
- Authors: Tabensky, Pedro , Matthews, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142084 , vital:38048 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
Change in Roviana Lagoon Coral Reef ethnobiology:
- Authors: Aswani, Shankar , Albert, Simon
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/145460 , vital:38440 , ISBN 9783319237633 , DOI: 10.1007/978-3-319-23763-3_10
- Description: Coral reefs are iconic for their beauty and biodiversity, and are of great socioeconomic and cultural importance for many coastal communities across the tropics. However, little is known about people’s local classification and their social and ecological relationship with these habitats. This chapter describes Roviana people’s changing ecological and social relationship with their coral reefs, which are increasingly being damaged by humans. First, we combined ecological and social data to describe people’s classification of local coral reefs in tandem with the productive practices conducted in these habitats. Second, we examined local perceptions and recognized effects of environmental and climatic changes on reefs over the last two decades. Finally, we measured changes in fishing activities and in the taxonomic systems (between 1995 and 2011) to evaluate if recent social and economic change has led to the erosion of marine indigenous ecological knowledge and associated practices. Studying people’s changing perceptions of their coral reefs is crucial to understand their ability to identify and adapt to environmental transformations. Simply, the way local people perceive the state of the environment is not only important in terms of changes in local epistemology but also has important implications for how resources are used and managed, and this information can be coupled with scientific one for a broader management strategy.
- Full Text:
- Date Issued: 2015
CHIP: a co-chaperone for degradation by the proteasome
- Authors: Edkins, Adrienne L
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/164863 , vital:41179 , ISBN 978-3-319-11730-0 , DOI: 10.1007/978-3-319-11731-7_11
- Description: Protein homeostasis relies on a balance between protein folding and protein degradation. Molecular chaperones like Hsp70 and Hsp90 fulfil well-defined roles in protein folding and conformational stability via ATP dependent reaction cycles. These folding cycles are controlled by associations with a cohort of non-client protein co-chaperones, such as Hop, p23 and Aha1. Pro-folding co-chaperones facilitate the transit of the client protein through the chaperone mediated folding process. However, chaperones are also involved in ubiquitin-mediated proteasomal degradation of client proteins. Similar to folding complexes, the ability of chaperones to mediate protein degradation is regulated by co-chaperones, such as the C terminal Hsp70 binding protein (CHIP).
- Full Text:
- Date Issued: 2015
Critical realism, environmental learning and social-ecological change
- Authors: Price, Leigh , Lotz-Sisitka, Heila
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/436952 , vital:73319 , ISBN 9781315660899 , https://www.routledge.com/Critical-Realism-Environmental-Learning-and-Social-Ecological-Change/Price-Lotz-Sistka/p/book/9780367597689
- Description: The contemporary social-ecological condition is characterized by power-ful changes in the way that we relate to each other and to the environ-ment. This has led to increased ecological vulnerability, which is also ac-companied by ongoing, and increased societal vulnerability. Nevertheless there remain opportunities for developing new social-ecological rela-tions, and for social-ecological learning and change. This would seem to require a strong project of recovering ontology, and a challenging and broadening of dominant ways of knowing (Mignolo, 2000) that also tend to commit what Bhaskar describes as the ‘epistemic fallacy’, or the ‘the analysis or reduction of being to knowledge of being’ (Bhaskar, 2010, p. 1). In response, Bhaskar (ibid.) suggests critical realism as an alternative that embodies a ‘compatibility of ontological realism, epistemological relativism and judgmental rationality’. This includes a ‘re-vindication of ontology’ and the possibility of recognizing and accounting for structure, difference and change in the world in ways that escape ontological actu-alism and ontological monovalence or ‘the generation of a purely positive account of reality’ (ibid., p. 15).
- Full Text:
- Date Issued: 2015
Ecological sustainability for non-timber forest products: dynamics and case studies of harvesting
- Authors: Shackleton, Charlie M , Pandey, Ashok K , Ticktin, Tamara
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/433656 , vital:72992 , ISBN 9781317916130 , https://www.routledge.com/Ecological-Sustainability-for-Non-timber-Forest-Products-Dynamics-and-Case/Shackleton-Pandey-Ticktin/p/book/9781138618251
- Description: There is growing knowledge about and appreciation of the im-portance of Non-timber Forest Products (NTFPs) to rural liveli-hoods in developing countries, and to a lesser extent, devel-oped countries. However, there is also an assumption on the part of policy-makers that any harvesting of wild animal or plant products from the forests and other natural and modi-fied ecosystems must be detrimental to the long-term viability of target populations and species. This book challenges this idea and shows that while examples of such negative impacts certainly exist, there are also many examples of sustainable harvesting systems for NTFPs. The chapters review and pre-sent coherent and scientifically sound information and case studies on the ecologically sustainable use of NTFPs. They also outline a general interdisciplinary approach for assessing the sustainability of NTFP harvesting systems at different scales. A wide range of case studies is included from Africa, Asia and South America, using plant and animal products for food, crafts, textiles, medicines and cosmetics.
- Full Text:
- Date Issued: 2015
Employing safe bets: reflections on attracting, developing and retaining the next generation of academics
- Authors: Hlengwa, Amanda I
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142145 , vital:38053 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
Hsp70/Hsp90 organising protein (hop): beyond interactions with chaperones and prion proteins
- Authors: Baindur-Hudson, Swati , Edkins, Adrienne L , Blatch, Gregory L
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/164852 , vital:41178 , ISBN 978-3-319-11730-0 , DOI: 10.1007/978-3-319-11731-7_3
- Description: The Hsp70/Hsp90 organising protein (Hop), also known as stress-inducible protein 1 (STI1), has received considerable attention for diverse cellular functions in both healthy and diseased states. There is extensive evidence that intracellular Hop is a co-chaperone of the major chaperones Hsp70 and Hsp90, playing an important role in the productive folding of Hsp90 client proteins. Consequently, Hop is implicated in a number of key signalling pathways, including aberrant pathways leading to cancer. However, Hop is also secreted and it is now well established that Hop also serves as a receptor for the prion protein, PrPC.
- Full Text:
- Date Issued: 2015
Making room for the unexpected: the university and the ethical imperative of unconditional hospitality
- Authors: Dass, Minesh
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142108 , vital:38050 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
Politics and discourse in South Africa:
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139249 , vital:37719 , ISBN 9789027206565 , https://benjamins.com/catalog/dapsac.65
- Description: The discourses of the post-apartheid South Africa embody symbols of change and promises of new lessons in history. This is the first volume that brings together analyses of a variety of discourses produced in South Africa through which we follow the evolution of transitional processes in the country’s political institutions and in the opinions of its populace. The book offers to the reader a visit to the Parliament, a peek into the internet forums, analyses of the country's official papers and speeches, and the media accounts. Through all these discourses we see the burning questions – "Who Are We Now?" and "Who Do We Want To Be?" – being repetitively examined and identities cross-formed while the country deals with new, post-apartheid challenges, as well as successes.
- Full Text:
- Date Issued: 2015
Representations of gender and agency in the Harry Potter series:
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139269 , vital:37721 , ISBN 978-1-137-43173-8 , https://doi.org/10.1057/9781137431738_13
- Description: Gender is an all-pervasive and extremely influential construct in the lives of individuals (Taylor, 2003). In children’s literature, we find a reflection of the attitudes towards gender prevalent in a given society at a particular time (Peterson and Lach, 1990). Therefore the study of how gender is represented in children’s literature can make a useful contribution to our understanding of how choices in language use support particular discourses, ‘broad constitutive systems of meaning’ (Sunderland, 2004: 6) or ‘ways of seeing the world’ (op cit: 28). These representations in turn perpetuate prevailing gendered power relations in that society, as research into children’s literature has shown (Thompson and Sealey, 2007). Corpus Linguistics offers a degree of objectivity and efficiency not possible in manual ideological analysis, as well as a set of tools particularly useful for the lexical analysis of considerable quantities of text. In this chapter, I report on my analysis of gendered discourses in the Harry Potter series by J. K. Rowling, focussing on patterns around grammatical agency in the books.
- Full Text:
- Date Issued: 2015
The 1990 Northern Areas "Uprising" in Port Elizabeth: A south African Story of Communities Resisting Oppression
- Date: 2015
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10948/41219 , vital:36417 , Bulk File 7
- Description: The Northern Areas History and Heritage Project consists of a variety workshops and materials examining the history of this part of Port Elizabeth to which people of colour had been removed in the 1970s. The materials include a book and DVD on the Northern Areas Uprising; six booklets entitled ‘Feasibility Study: Imagining a Cultural/ Healing Centre for the Northern Areas of Nelson Mandela Bay’ covering topics such as the Northern Areas Uprising, healing through memorialisation, architecture, non-profit organisations, archives and databases; 35 DVDs consisting of interviews with individuals, communities and focus groups, as well as a Winter School Project on Apartheid and the Group Areas Act. Also included are two maps relating to the area’s history.
- Full Text: false
- Date Issued: 2015
The countercultural university:
- Authors: Tabensky, Pedro
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142133 , vital:38052 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
The violence beneath the veil of politeness: reflections on race and power in the academy
- Authors: Njovane, Thandokazi
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142121 , vital:38051 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
What about the queers?: the institutional culture of heteronormativity and its implications for queer staff and students
- Authors: Donaldson, Natalie
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142051 , vital:38045 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
White privilege and institutional culture at South African higher education institutions:
- Authors: Matthews, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142097 , vital:38049 , ISBN 9781869142902 , https://books.google.co.za/books?id=49o8rgEACAAJanddq=Being+at+home:+Race,+institutional+culture+and+transformation+at+South+African+higher+education+institutionandhl=enandsa=Xandved=0ahUKEwiPgsa6mpjjAhXNN8AKHbNwAtoQ6AEIKDAA
- Description: This edited work has gathered together contributions on how to transform universities in South Africa; as many are struggling to shift their institutional culture. In a South African context, transformation means to attempt to change higher education institutions such that they no longer reflect the values promoted by apartheid but rather reflect the values embodied in South Africa's 1996 Constitution. Institutional culture is the main subject for discussion in this book. In order to transform South Africa's universities, the contributors begin by analyzing the idea of what a university is, and relatedly, what its ideal aims are. A second theme is to understand what institutional culture is and how it functions. Moreover, transformation cannot occur without transforming the broader cultures of which they are a part. Related to this theme is a general concern about how contemporary moves towards the instrumentalization of higher education affect the ability to transform institutions. These institutions are being pushed to conform to goals that are outside the traditional idea of a university, such as concerns that universities are being 'bureaucratized' and becoming corporations, instead of a place of learning open to all. In conclusion it can be said that the contemporary South African academic community has an opportunity to recreate itself as the end of apartheid created space for engaging in transformative epistemic projects. The transformation of the tertiary sector entails a transformation of institutional cultures.
- Full Text:
- Date Issued: 2015
“Mother of the Nation”: representations of womanhood in South African media
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139229 , vital:37717 , ISBN 9789027206565 , https://benjamins.com/catalog/dapsac.65
- Description: The discourses of the post-apartheid South Africa embody symbols of change and promises of new lessons in history. This is the first volume that brings together analyses of a variety of discourses produced in South Africa through which we follow the evolution of transitional processes in the country’s political institutions and in the opinions of its populace. The book offers to the reader a visit to the Parliament, a peek into the internet forums, analyses of the country's official papers and speeches, and the media accounts. Through all these discourses we see the burning questions – "Who Are We Now?" and "Who Do We Want To Be?" – being repetitively examined and identities cross-formed while the country deals with new, post-apartheid challenges, as well as successes.
- Full Text:
- Date Issued: 2015
Bioinformatics and data analysis in microbiology:
- Authors: Tastan Bishop, Özlem
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/148104 , vital:38710 , ISBN 9781908230737 , https://books.google.co.za/books?id=-G07DwAAQBAJanddq=Bioinformatics+and+data+analysis+in+microbiologyandsource=gbs_navlinks_s
- Description: The rapid advancement of sequencing techniques, coupled with the new methodologies of bioinformatics to handle large-scale data analysis, are providing exciting opportunities for us to understand microbial communities from a variety of environments beyond previous imagination. This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a problem, talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The chapters include topics such as genome sequencing techniques, assembly, SNP analysis, annotation, comparative genomics, microbial community profiling, metagenomics, phylogenetic microarrays, barcoding and more. Each chapter is written by scientists who are expert in the field, and is peer-reviewed. Bioinformatics and Data Analysis in Microbiology is an essential book for researchers, lecturers and students involved in microbiology, bioinformatics and genome analysis.
- Full Text:
- Date Issued: 2014
General structural and functional features of molecular chaperones:
- Authors: Edkins, Adrienne L , Boshoff, Aileen
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/164808 , vital:41174 , ISBN 978-94-007-7437-7 , DOI: 10.1007/978-94-007-7438-4_2
- Description: Molecular chaperones are a group of structurally diverse and highly conserved ubiquitous proteins. They play crucial roles in facilitating the correct folding of proteins in vivo by preventing protein aggregation or facilitating the appropriate folding and assembly of proteins. Heat shock proteins form the major class of molecular chaperones that are responsible for protein folding events in the cell. This is achieved by ATP-dependent (folding machines) or ATP-independent mechanisms (holders). Heat shock proteins are induced by a variety of stresses, besides heat shock. The large and varied heat shock protein class is categorised into several subfamilies based on their sizes in kDa namely, small Hsps (HSPB), Hsp40 (DNAJ), Hsp60 (HSPD/E; Chaperonins), Hsp70 (HSPA), Hsp90 (HSPC), and Hsp100.
- Full Text:
- Date Issued: 2014