From more sustainable isocyanide-based multicomponent reactions to spiro-heterocyclic compound syntheses
- Authors: Salami, Sodeeq Aderotimi
- Date: 2023-10-13
- Subjects: Passerini reaction , Isocyanides , Isothiocyanate , Mechanical chemistry , Organic reaction
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/432229 , vital:72853 , DOI 10.21504/10962/432229
- Description: The global pharmaceutical industry has undergone profound transformations in the past two decades in the search for new drugs. For this reason, most pharmaceutical companies made significant investments not only in the development of new drugs but new methodologies. Modern drug development is confronted with the challenge of developing chemical reactions that are highly capable of providing most of the elements of structural complexity and diversity with the fewest possible synthetic steps for the specific target with the most intriguing properties. The discovery of more sustainable, environmentally friendly reactions capable of forming multiple bonds in a single step has been a challenge in organic synthesis over the years. Many organic chemists have recently started focusing on creative ways of reducing environmental pollution. The use of hazardous solvents has been reduced or eliminated in research to limit harm to both people and the environment. The pursuit of this goal has drawn many organic chemists to the study of various sustainable synthetic techniques including catalysis, aqueous organic reactions and mechanochemistry. The scope of this thesis was to apply sustainable techniques to design multicomponent synthetic protocols for the Passerini reaction and further apply these new protocols to construct spiro-heterocyclic compounds, all based on green chemistry principles. There is a need to develop rapid, efficient, and versatile strategies for the synthesis of bioactive molecules via multicomponent reactions. This project tried to avoid some of the pitfalls of traditional approaches, such as toxicity, low yield, long reaction times, harsh conditions, experimental complexity, and limited functionalization scope. This was achieved by focussing on the use of isonitriles and isothiocyanates as key reactive intermediates, and making extensive use of aqueous reaction conditions, mechanochemistry and microwave activation. , Thesis (PhD) -- Faculty of Science, Chemistry, 2023
- Full Text:
- Date Issued: 2023-10-13
- Authors: Salami, Sodeeq Aderotimi
- Date: 2023-10-13
- Subjects: Passerini reaction , Isocyanides , Isothiocyanate , Mechanical chemistry , Organic reaction
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/432229 , vital:72853 , DOI 10.21504/10962/432229
- Description: The global pharmaceutical industry has undergone profound transformations in the past two decades in the search for new drugs. For this reason, most pharmaceutical companies made significant investments not only in the development of new drugs but new methodologies. Modern drug development is confronted with the challenge of developing chemical reactions that are highly capable of providing most of the elements of structural complexity and diversity with the fewest possible synthetic steps for the specific target with the most intriguing properties. The discovery of more sustainable, environmentally friendly reactions capable of forming multiple bonds in a single step has been a challenge in organic synthesis over the years. Many organic chemists have recently started focusing on creative ways of reducing environmental pollution. The use of hazardous solvents has been reduced or eliminated in research to limit harm to both people and the environment. The pursuit of this goal has drawn many organic chemists to the study of various sustainable synthetic techniques including catalysis, aqueous organic reactions and mechanochemistry. The scope of this thesis was to apply sustainable techniques to design multicomponent synthetic protocols for the Passerini reaction and further apply these new protocols to construct spiro-heterocyclic compounds, all based on green chemistry principles. There is a need to develop rapid, efficient, and versatile strategies for the synthesis of bioactive molecules via multicomponent reactions. This project tried to avoid some of the pitfalls of traditional approaches, such as toxicity, low yield, long reaction times, harsh conditions, experimental complexity, and limited functionalization scope. This was achieved by focussing on the use of isonitriles and isothiocyanates as key reactive intermediates, and making extensive use of aqueous reaction conditions, mechanochemistry and microwave activation. , Thesis (PhD) -- Faculty of Science, Chemistry, 2023
- Full Text:
- Date Issued: 2023-10-13
Phytoplankton communities provide insight into ecosystem functioning of the Agulhas Current system
- Authors: Gibb, Ross-Lynne Alida
- Date: 2023-03-31
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/422646 , vital:71965
- Description: Access restricted. Embargoed until 2025. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2023
- Full Text:
- Date Issued: 2023-03-31
- Authors: Gibb, Ross-Lynne Alida
- Date: 2023-03-31
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/422646 , vital:71965
- Description: Access restricted. Embargoed until 2025. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2023
- Full Text:
- Date Issued: 2023-03-31
Saul Msane: friend or foe of the people? The life of the late nineteenth to early twentieth centuries South African politician and journalist
- Authors: Mokoatsi, Thapelo
- Date: 2023-03-30
- Subjects: Saul Msane , Elite (Social sciences) , African National Congress , Politicians South Africa Biography , Political dispute , Abantu-Batho , Enemy of the people
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/409799 , vital:70631 , DOI 10.21504/10962/409802
- Description: Saul Msane was a prominent founding member of the ANC and an active journalist and editor of the ANC newspaper Abantu-Batho. His career generated controversy. Towards the end of his life, he had a feud with his colleagues in the African National Congress (henceforth Congress) that led to him being labelled isitha sabantu, “the enemy of the people” for his refusal to support the Shilling strike of 1918, an accusation which was retracted a year after his death in 1919. The label of isitha sabantu levelled against Msane, had the effect of ending his political prominence in the Transvaal, forcing him to relocate to kwaNongoma where he died shortly thereafter. Msane’s years in the Congress amounted to about seven years, between 1912, the founding of the Congress, and the demise of his career in 1919. Msane’s seven years in Congress were characterised by controversies, clashes, and conflicts owing to his perceived elitism. In Congress historiography Msane is an obscure and elusive figure, he lives here and there in a footnote, as a supporting statement or a mentioned in mere passing. His marginalisation reveals some of the gaps within the history of Congress and invites us to write about those who did not emerge from the history of Congress necessarily as heroes. This thesis sets out to write a biography of Msane and document his political career beyond that one moment in which he came to be “isitha sabantu”. While Msane’s Congress career was comparably short and filled with tensions, an archive of his life exists. This study is an exploration of that archive to reconstruct the biography of a once prominent leader who dies in political exile from the Congress movement. This thesis sets out to do two key things in relation to reconstructing Msane’s life: Firstly, it reconstructs the longer biography of Msane’s political life by drawing on the existing archives, and thus filling in the South African historical record in that regard. Secondly, at the broader conceptual and historiographical level, it argues that the controversies surrounding Msane’s persona and character illustrate that conceptions of elitism and the nature of being ‘elite’ were key to the politics of Congress at the time. , U-Saul Msane wayengomunye wabasunguli beqembu lika-African National Congress (uKhongolose) futhi eyIntatheli nomhleli wephephandaba i-Abantu-Batho. Umsebenzi ayewenza waba nezingqinamba eziningi ngokwezepolitiki. Ngasekugcineni kwempilo yakhe waba nokungazwani nabaholi ayesebenza nabo kuKhongolose okwadala ukuba abizwe ngesitha sabantu ngenxa yokuba engavumelananga nesiteleka sango-1918 lapho abasebenzi babelwela ukukhushulelwa amaholo. Leligama lokubizwa ngesitha sabantu lahoxiswa ngo 1919 sekudlule unyaka engasekho emhlabeni. Lokubizwa ngesitha sabantu kwalilimaza igama lakhe kwezepolitiki e-Transvaal waze wathutha wayohlala kwaNongoma nokuyilapho ashonela khona. Iminyaka uMsane ayisebenzele uKhongolose yaba isikhombisa, kusukela ekusungulweni kwayo ngo 1912 kuze kufike ekulimaleni komsebenzi wakhe wezepolitiki ngo 1919. Kuleminyaka eyisikhombisa umsebenzi wakhe kuKhongolose wawubhekene nokugxekwa okukhulu nokubukeka njengomuntu onokuzenza ngcono kunabanye abantu. Emlandweni kaKhongolose uMsane akavezwa ngendlela emfanele, kukhulunywa ngaye kudlulwa nje. Lokunganakwa kukaMsane emlandweni kaKhongolose kusiphoqa ukuba sibhale ngabaholi abangaqakanjiswa. Lolucwaningo luveza umlando kaMsane ngokujulile ngaphezu kwangalesikhathi abizwa khona ngesitha sabantu. Noma umsebenzi kaMsane kuKhongolose wabamfushane kunabanye futhi ugcwele izinto kodwa noko ingobo yawo ikhona. Lolucwaningo lucubungula lengobo ukuhlaziya nokubhala kabusha umlando wengqalabutho eyagcina ishonela ngaphandle kombutho kaKhongolose. Loluphando lifisa ukwenza izinto ezimbili: Okokuqala, ibhala kabusha umlando omude wezepolitiki kaMsane kusetshenziswa ulwazi olukhona. Loku kuzosiza ukunothisa umlando wezepolitiki wezwe laseNingizimu Afrika. Okwesibili, ezingeni lobunzululwazi, lolucwaningo luveza ukuthi izinkinga uMsane ahlangabezana nazo zazisukele endleleni okwakubukwa ngayo indaba yokucwasana ngazinga empilo abantu, kwakuyinto ejulile kuKhongolose ukubukeka kwabanye sengathi bazenza ngcono. , Thesis (PhD) -- Faculty of Humanities, History, 2023
- Full Text:
- Date Issued: 2023-03-30
- Authors: Mokoatsi, Thapelo
- Date: 2023-03-30
- Subjects: Saul Msane , Elite (Social sciences) , African National Congress , Politicians South Africa Biography , Political dispute , Abantu-Batho , Enemy of the people
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/409799 , vital:70631 , DOI 10.21504/10962/409802
- Description: Saul Msane was a prominent founding member of the ANC and an active journalist and editor of the ANC newspaper Abantu-Batho. His career generated controversy. Towards the end of his life, he had a feud with his colleagues in the African National Congress (henceforth Congress) that led to him being labelled isitha sabantu, “the enemy of the people” for his refusal to support the Shilling strike of 1918, an accusation which was retracted a year after his death in 1919. The label of isitha sabantu levelled against Msane, had the effect of ending his political prominence in the Transvaal, forcing him to relocate to kwaNongoma where he died shortly thereafter. Msane’s years in the Congress amounted to about seven years, between 1912, the founding of the Congress, and the demise of his career in 1919. Msane’s seven years in Congress were characterised by controversies, clashes, and conflicts owing to his perceived elitism. In Congress historiography Msane is an obscure and elusive figure, he lives here and there in a footnote, as a supporting statement or a mentioned in mere passing. His marginalisation reveals some of the gaps within the history of Congress and invites us to write about those who did not emerge from the history of Congress necessarily as heroes. This thesis sets out to write a biography of Msane and document his political career beyond that one moment in which he came to be “isitha sabantu”. While Msane’s Congress career was comparably short and filled with tensions, an archive of his life exists. This study is an exploration of that archive to reconstruct the biography of a once prominent leader who dies in political exile from the Congress movement. This thesis sets out to do two key things in relation to reconstructing Msane’s life: Firstly, it reconstructs the longer biography of Msane’s political life by drawing on the existing archives, and thus filling in the South African historical record in that regard. Secondly, at the broader conceptual and historiographical level, it argues that the controversies surrounding Msane’s persona and character illustrate that conceptions of elitism and the nature of being ‘elite’ were key to the politics of Congress at the time. , U-Saul Msane wayengomunye wabasunguli beqembu lika-African National Congress (uKhongolose) futhi eyIntatheli nomhleli wephephandaba i-Abantu-Batho. Umsebenzi ayewenza waba nezingqinamba eziningi ngokwezepolitiki. Ngasekugcineni kwempilo yakhe waba nokungazwani nabaholi ayesebenza nabo kuKhongolose okwadala ukuba abizwe ngesitha sabantu ngenxa yokuba engavumelananga nesiteleka sango-1918 lapho abasebenzi babelwela ukukhushulelwa amaholo. Leligama lokubizwa ngesitha sabantu lahoxiswa ngo 1919 sekudlule unyaka engasekho emhlabeni. Lokubizwa ngesitha sabantu kwalilimaza igama lakhe kwezepolitiki e-Transvaal waze wathutha wayohlala kwaNongoma nokuyilapho ashonela khona. Iminyaka uMsane ayisebenzele uKhongolose yaba isikhombisa, kusukela ekusungulweni kwayo ngo 1912 kuze kufike ekulimaleni komsebenzi wakhe wezepolitiki ngo 1919. Kuleminyaka eyisikhombisa umsebenzi wakhe kuKhongolose wawubhekene nokugxekwa okukhulu nokubukeka njengomuntu onokuzenza ngcono kunabanye abantu. Emlandweni kaKhongolose uMsane akavezwa ngendlela emfanele, kukhulunywa ngaye kudlulwa nje. Lokunganakwa kukaMsane emlandweni kaKhongolose kusiphoqa ukuba sibhale ngabaholi abangaqakanjiswa. Lolucwaningo luveza umlando kaMsane ngokujulile ngaphezu kwangalesikhathi abizwa khona ngesitha sabantu. Noma umsebenzi kaMsane kuKhongolose wabamfushane kunabanye futhi ugcwele izinto kodwa noko ingobo yawo ikhona. Lolucwaningo lucubungula lengobo ukuhlaziya nokubhala kabusha umlando wengqalabutho eyagcina ishonela ngaphandle kombutho kaKhongolose. Loluphando lifisa ukwenza izinto ezimbili: Okokuqala, ibhala kabusha umlando omude wezepolitiki kaMsane kusetshenziswa ulwazi olukhona. Loku kuzosiza ukunothisa umlando wezepolitiki wezwe laseNingizimu Afrika. Okwesibili, ezingeni lobunzululwazi, lolucwaningo luveza ukuthi izinkinga uMsane ahlangabezana nazo zazisukele endleleni okwakubukwa ngayo indaba yokucwasana ngazinga empilo abantu, kwakuyinto ejulile kuKhongolose ukubukeka kwabanye sengathi bazenza ngcono. , Thesis (PhD) -- Faculty of Humanities, History, 2023
- Full Text:
- Date Issued: 2023-03-30
“It’s not just me on a video call with someone…” Students’ experiences of a forced transition from face-to-face psychotherapy to online psychotherapy during COVID-19: an interpretative phenomenological analysis
- Authors: Keet, Nicole Tahnee
- Date: 2023-03-30
- Subjects: Online therapy , COVID-19 Pandemic, 2020- Influence , Interpretative phenomenological analysis , Psychologists Training of , College students Attitudes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408845 , vital:70531
- Description: The aim of this study is to explore university students’ experience of a forced transition from face-to-face therapy to online therapy during COVID-19. This pandemic was unexpected and affected all areas of life, including the closure of universities, which left therapists and clients alike unsure of how to navigate these unchartered territories. Although there is a considerable amount of international research on experiences of online therapy, there is little research on a forced transition to online therapy because of COVID-19 and even less within the South African context. A sample of six participants between the ages of 20 and 30 years old were selected through purposive and convenience sampling. Semi-structured interviews were conducted, and interpretative Phenomenological Analysis (IPA) was utilised to ascertain how participants make sense of their worlds in relation to the transition to online therapy. The analysis provided three main superordinate themes, which are supported by subordinate themes. The superordinate themes are: 1) Online therapy as authentic and continuous, where the participants experienced the comfort and convenience of online therapy, the continuity of care and the anonymity of online therapy. 2) Online therapy as disruptive and invasive, where participants experienced issues with privacy, an intrusive environment, technological challenges, lack of body language and therapy feeling more disposable. 3) Getting used to online therapy with some help from the therapist, where participants felt an adjustment period was necessary as well as transparency and containment from the therapist to help with the transition. These findings support some existing South African literature; however, it also engages with findings unique to this study, that will hopefully be used for further exploration. The study ends with recommendations for training therapists on using online therapy. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
- Authors: Keet, Nicole Tahnee
- Date: 2023-03-30
- Subjects: Online therapy , COVID-19 Pandemic, 2020- Influence , Interpretative phenomenological analysis , Psychologists Training of , College students Attitudes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408845 , vital:70531
- Description: The aim of this study is to explore university students’ experience of a forced transition from face-to-face therapy to online therapy during COVID-19. This pandemic was unexpected and affected all areas of life, including the closure of universities, which left therapists and clients alike unsure of how to navigate these unchartered territories. Although there is a considerable amount of international research on experiences of online therapy, there is little research on a forced transition to online therapy because of COVID-19 and even less within the South African context. A sample of six participants between the ages of 20 and 30 years old were selected through purposive and convenience sampling. Semi-structured interviews were conducted, and interpretative Phenomenological Analysis (IPA) was utilised to ascertain how participants make sense of their worlds in relation to the transition to online therapy. The analysis provided three main superordinate themes, which are supported by subordinate themes. The superordinate themes are: 1) Online therapy as authentic and continuous, where the participants experienced the comfort and convenience of online therapy, the continuity of care and the anonymity of online therapy. 2) Online therapy as disruptive and invasive, where participants experienced issues with privacy, an intrusive environment, technological challenges, lack of body language and therapy feeling more disposable. 3) Getting used to online therapy with some help from the therapist, where participants felt an adjustment period was necessary as well as transparency and containment from the therapist to help with the transition. These findings support some existing South African literature; however, it also engages with findings unique to this study, that will hopefully be used for further exploration. The study ends with recommendations for training therapists on using online therapy. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
Bioinformatics tool and web server development focusing on structural bioinformatics applications
- Authors: Nabatanzi, Margaret
- Date: 2022-10-14
- Subjects: Structural bioinformatics , Proteins Structure , Protein structure prediction , Proteins Conformation , Protein complex
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365700 , vital:65777 , DOI https://doi.org/10.21504/10962/365700
- Description: This thesis is divided into two main sections: Part 1 describes the design, and evaluation of the accuracy of a new web server – PRotein Interactive MOdeling (PRIMO-Complexes) for modeling protein complexes and biological assemblies. The second part describes the development of bioinformatics tools to predict HIV-1 drug resistance and support bioinformatics research and education. Recent technological advances have resulted in a tremendous increase in the number of sequences and protein structures deposited in the Universal Protein Resource Knowledgebase (UniProtKB) and the Protein Data Bank (PDB). However, the number of sequences has increased at a higher rate compared with the experimentally solved multimeric protein structures. This is partly due to advances in high-throughput sequencing technology. To fill this protein sequence-structure gap, computational approaches have been developed to predict protein structures from available sequences. Computational approaches include template-based and ab initio modeling with the former being the most reliable. Template-based modeling process can be achieved using either standalone software or automated modeling web servers. However, using standalone software requires familiarity with command-line interfaces as well as utilising other intermediate programs which could be daunting to novice users. To alleviate some of these problems, the modeling process has been automated, however, it still has numerous challenges. To date, only a few web servers that support multimeric protein modeling have been developed and even these provide little, if any user involvement in the process. To address some of these issues, a new web server – PRIMO-Complexes – was developed to model protein complexes and biological assemblies. The existing PRIMO web server could only model monomeric proteins. Part 1 of this thesis provides a detailed account of the development and evaluation of PRIMO-Complexes. The rationale for developing this new web server was based on the understanding that most proteins function as protein multimers and often the ligand-binding sites, and enzyme active sites are located at the protein-protein interfaces. It, therefore, necessitated developing capabilities for modeling multimeric proteins. PRIMO-Complexes web server was developed using the Waterfall system development life cycle model, is based on the Django web framework and makes use of high-performance computing resources to execute jobs. The accuracy of the algorithms embedded in PRIMO- Complexes was evaluated and the results were promising. Additionally, PRIMO-Complexes performs comparatively well in relation to other web servers that offer multimeric protein modeling. Another unique feature of PRIMO-Complexes is its interactivity. The webserver was developed with capabilities for allowing users to model multimeric proteins with an appreciable degree of control over the process. In the second part of the thesis several other bioinformatics tools are described, for example, a webserver for predicting HIV-1 drug resistance, the RUBi protein model repository, and a bioinformatics web portal for education and research resources. RUBi protein model repository stores verified theoretical models built using various modeling approaches. This enables users to easily access models to reproduce and/or further the research. This is described in chapter 5. Chapter 6 describes the design and development of the Human Immunodeficiency type 1 Resistance Predictor (HIV-1 ResPredictor), a web application that employs artificial neural networks (ANN) to predict drug resistance in patients infected with HIV-1 subtype B. The ANNs and subtype classifiers performed well making this web application potentially useful to both clinicians and researchers in this era of personalised medicine. Finally, chapter 7 describes a bioinformatics education web portal that equips students with information on how to use bioinformatics online resources. Being aware of these resources is not enough without a deeper understanding and guidance on how to apply bioinformatics methods to solve practical problems. This web portal was aimed at familiarising students with the basic terminology and approaches in structural bioinformatics. Students will potentially gain skills to conduct real-life bioinformatics research to obtain biological insights. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Nabatanzi, Margaret
- Date: 2022-10-14
- Subjects: Structural bioinformatics , Proteins Structure , Protein structure prediction , Proteins Conformation , Protein complex
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365700 , vital:65777 , DOI https://doi.org/10.21504/10962/365700
- Description: This thesis is divided into two main sections: Part 1 describes the design, and evaluation of the accuracy of a new web server – PRotein Interactive MOdeling (PRIMO-Complexes) for modeling protein complexes and biological assemblies. The second part describes the development of bioinformatics tools to predict HIV-1 drug resistance and support bioinformatics research and education. Recent technological advances have resulted in a tremendous increase in the number of sequences and protein structures deposited in the Universal Protein Resource Knowledgebase (UniProtKB) and the Protein Data Bank (PDB). However, the number of sequences has increased at a higher rate compared with the experimentally solved multimeric protein structures. This is partly due to advances in high-throughput sequencing technology. To fill this protein sequence-structure gap, computational approaches have been developed to predict protein structures from available sequences. Computational approaches include template-based and ab initio modeling with the former being the most reliable. Template-based modeling process can be achieved using either standalone software or automated modeling web servers. However, using standalone software requires familiarity with command-line interfaces as well as utilising other intermediate programs which could be daunting to novice users. To alleviate some of these problems, the modeling process has been automated, however, it still has numerous challenges. To date, only a few web servers that support multimeric protein modeling have been developed and even these provide little, if any user involvement in the process. To address some of these issues, a new web server – PRIMO-Complexes – was developed to model protein complexes and biological assemblies. The existing PRIMO web server could only model monomeric proteins. Part 1 of this thesis provides a detailed account of the development and evaluation of PRIMO-Complexes. The rationale for developing this new web server was based on the understanding that most proteins function as protein multimers and often the ligand-binding sites, and enzyme active sites are located at the protein-protein interfaces. It, therefore, necessitated developing capabilities for modeling multimeric proteins. PRIMO-Complexes web server was developed using the Waterfall system development life cycle model, is based on the Django web framework and makes use of high-performance computing resources to execute jobs. The accuracy of the algorithms embedded in PRIMO- Complexes was evaluated and the results were promising. Additionally, PRIMO-Complexes performs comparatively well in relation to other web servers that offer multimeric protein modeling. Another unique feature of PRIMO-Complexes is its interactivity. The webserver was developed with capabilities for allowing users to model multimeric proteins with an appreciable degree of control over the process. In the second part of the thesis several other bioinformatics tools are described, for example, a webserver for predicting HIV-1 drug resistance, the RUBi protein model repository, and a bioinformatics web portal for education and research resources. RUBi protein model repository stores verified theoretical models built using various modeling approaches. This enables users to easily access models to reproduce and/or further the research. This is described in chapter 5. Chapter 6 describes the design and development of the Human Immunodeficiency type 1 Resistance Predictor (HIV-1 ResPredictor), a web application that employs artificial neural networks (ANN) to predict drug resistance in patients infected with HIV-1 subtype B. The ANNs and subtype classifiers performed well making this web application potentially useful to both clinicians and researchers in this era of personalised medicine. Finally, chapter 7 describes a bioinformatics education web portal that equips students with information on how to use bioinformatics online resources. Being aware of these resources is not enough without a deeper understanding and guidance on how to apply bioinformatics methods to solve practical problems. This web portal was aimed at familiarising students with the basic terminology and approaches in structural bioinformatics. Students will potentially gain skills to conduct real-life bioinformatics research to obtain biological insights. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
Evaluating the role of Stress Induced Phosphoprotein 1 isoforms in Kaposi's Sarcoma-Associated Herpesvirus biology
- Authors: Ruck, Duncan Kyle
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/365280 , vital:65723
- Description: Thesis embargoed. Possible release date set for early 2025. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Ruck, Duncan Kyle
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/365280 , vital:65723
- Description: Thesis embargoed. Possible release date set for early 2025. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
Identification and characterisation of microbial communities and their metabolic potential in meltwater ponds, Western Dronning Mau Land, Antarctica
- Authors: Van Aswegen, Sunet
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365723 , vital:65779
- Description: Thesis embargoed. Expected release date early 2024. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Van Aswegen, Sunet
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365723 , vital:65779
- Description: Thesis embargoed. Expected release date early 2024. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
A content analysis of public academic literature that explores the relationship between gang membership and identity in South African prisons, focusing on group processes
- Yantolo, Siphosethu https://orcid.org/0000-0002-3011-3458
- Authors: Yantolo, Siphosethu https://orcid.org/0000-0002-3011-3458
- Date: 2022-09
- Subjects: Gang members -- South Africa , Prison gangs -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27253 , vital:66485
- Description: Prison gangs are currently prevalent in South African correctional facilities, and they have a devastating impact on the lives of many young men in South African jails and society (Nel, 2017). The purpose of this study was to examine scholarly literature on the topic of gang membership and its link with identity in South African prisons, with a focus on group processes. This study examined published academic literature and analyzed it using a mixed-method approach that included content analysis. The literature was examined using keywords, theoretical background, article kinds, participant gender, participant age, and author affiliation. Furthermore, themes were developed by qualitatively assessing the problem statements of the associated papers and identifying their consequences. Most of the research on gang membership and identification in jail focused on prison gang members and, to a lesser extent, non-gang members, with minimal focus on correctional services authorities. The findings on author affiliation revealed that most of the authors were linked with South African universities. The qualitative findings of this study revealed that Rule Violation, Power and Status, and the Need for Belonging are the most dominating themes relating to group processes and have a substantial influence on prison gang membership. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Yantolo, Siphosethu https://orcid.org/0000-0002-3011-3458
- Date: 2022-09
- Subjects: Gang members -- South Africa , Prison gangs -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27253 , vital:66485
- Description: Prison gangs are currently prevalent in South African correctional facilities, and they have a devastating impact on the lives of many young men in South African jails and society (Nel, 2017). The purpose of this study was to examine scholarly literature on the topic of gang membership and its link with identity in South African prisons, with a focus on group processes. This study examined published academic literature and analyzed it using a mixed-method approach that included content analysis. The literature was examined using keywords, theoretical background, article kinds, participant gender, participant age, and author affiliation. Furthermore, themes were developed by qualitatively assessing the problem statements of the associated papers and identifying their consequences. Most of the research on gang membership and identification in jail focused on prison gang members and, to a lesser extent, non-gang members, with minimal focus on correctional services authorities. The findings on author affiliation revealed that most of the authors were linked with South African universities. The qualitative findings of this study revealed that Rule Violation, Power and Status, and the Need for Belonging are the most dominating themes relating to group processes and have a substantial influence on prison gang membership. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
A Critical Assessment of the Legal and Policy Frameworks for Combating Child Trafficking in the Southern African Development Community
- Muvhevhi, Roseline Rumbidzai https://orcid.org/0009-0006-1024-5548
- Authors: Muvhevhi, Roseline Rumbidzai https://orcid.org/0009-0006-1024-5548
- Date: 2022-09
- Subjects: Child trafficking -- Law and legislation -- Africa, Southern , Child welfare -- Africa, Southern
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26728 , vital:65969
- Description: Child trafficking is a longstanding problem which affects victims and communities in various ways and therefore requires stern action both at the global and regional level. In the Southern African Development Community (SADC) region, the crime is closely connected to the existing socio-economic challenges such as poverty; underdevelopment; lack of equal economic opportunities; HIV/AIDS; and human rights violations. As a result, SADC States are fertile sources, transit zones and destinations for child trafficking. It is internationally recognised that it is States such as those in the SADC region that require a comprehensive approach to prevent and prosecute the crime while simultaneously ensuring victim protection. To this effect, the Protocol to Prevent, Suppress and Punish Trafficking in Persons Especially Women and Children is the primary instrument that seeks to provide such a comprehensive approach to child trafficking. Therefore, the current regional and national responses to child trafficking in most SADC States, are influenced by this Protocol. Despite these legislative and policy efforts to combat the crime, statistics show that in recent years child trafficking has been rapidly increasing in SADC. Thus, this research seeks to investigate why child trafficking remains prevalent in the region despite a plethora of measures against the crime. The research, therefore, assesses the effectiveness of the legal and policy measures taken by the SADC States to combat child trafficking using a qualitative approach involving analysis and interpretation of relevant legislation and policies. The primary focus is on the Trafficking Protocol as the main child trafficking instrument at the international level. The role of non-child trafficking instruments in the absence of a community instrument against the crime in SADC is also analysed. This research observes that the increasing child trafficking problem in the region is not mainly because of a lack of adequate legislation or policies but the lack of effective implementation of measures. Without a regional comprehensive and coordinated implementation approach, these measures remain weak and inadequate to fully combat child trafficking in the region. To this end, numerous legislative, policy, institutional and operational reform mechanisms to strengthen the subsisting measures against child trafficking in the region and areas for further research are recommended. , Thesis (LLD) -- Faculty of Law, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Muvhevhi, Roseline Rumbidzai https://orcid.org/0009-0006-1024-5548
- Date: 2022-09
- Subjects: Child trafficking -- Law and legislation -- Africa, Southern , Child welfare -- Africa, Southern
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26728 , vital:65969
- Description: Child trafficking is a longstanding problem which affects victims and communities in various ways and therefore requires stern action both at the global and regional level. In the Southern African Development Community (SADC) region, the crime is closely connected to the existing socio-economic challenges such as poverty; underdevelopment; lack of equal economic opportunities; HIV/AIDS; and human rights violations. As a result, SADC States are fertile sources, transit zones and destinations for child trafficking. It is internationally recognised that it is States such as those in the SADC region that require a comprehensive approach to prevent and prosecute the crime while simultaneously ensuring victim protection. To this effect, the Protocol to Prevent, Suppress and Punish Trafficking in Persons Especially Women and Children is the primary instrument that seeks to provide such a comprehensive approach to child trafficking. Therefore, the current regional and national responses to child trafficking in most SADC States, are influenced by this Protocol. Despite these legislative and policy efforts to combat the crime, statistics show that in recent years child trafficking has been rapidly increasing in SADC. Thus, this research seeks to investigate why child trafficking remains prevalent in the region despite a plethora of measures against the crime. The research, therefore, assesses the effectiveness of the legal and policy measures taken by the SADC States to combat child trafficking using a qualitative approach involving analysis and interpretation of relevant legislation and policies. The primary focus is on the Trafficking Protocol as the main child trafficking instrument at the international level. The role of non-child trafficking instruments in the absence of a community instrument against the crime in SADC is also analysed. This research observes that the increasing child trafficking problem in the region is not mainly because of a lack of adequate legislation or policies but the lack of effective implementation of measures. Without a regional comprehensive and coordinated implementation approach, these measures remain weak and inadequate to fully combat child trafficking in the region. To this end, numerous legislative, policy, institutional and operational reform mechanisms to strengthen the subsisting measures against child trafficking in the region and areas for further research are recommended. , Thesis (LLD) -- Faculty of Law, 2022
- Full Text:
- Date Issued: 2022-09
An investigation in waste management in Enoch Mgijima Local Municipality: a case study in Whittlesea
- Mngese, Bongani Elvis https://orcid.org/0000-0003-3222-0764
- Authors: Mngese, Bongani Elvis https://orcid.org/0000-0003-3222-0764
- Date: 2022-09
- Subjects: Refuse and refuse disposal -- Law and legislation -- South Africa , Local government -- Law and legislation -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/28784 , vital:74921
- Description: The study investigates the state of rendering waste service to Whittlesea within the Enoch Mgijima Local Municipality (EMLM). The study assesses into local municipality waste management policy and how the everyday attitude on waste handling has impacted on waste management. The study responds to the contextual gap in EMLM waste service delivery to Whittlesea community. The study addresses the following key research questions: What is the waste management policy in Enoch Mgijima Local Municipality? How was the waste management policy implemented by municipal mangers in Enoch Mgijima Local Municipality to Whittlesea? How did the community of Whittlesea respond to the waste management service delivery of Enoch Mgijima Local Municipality? The study used a qualitative approach, the data collection instruments included document review of policy and other official document, and in-depth interviews of respondents from the municipality and the community. The key findings of this research study were as follows- firstly, the national policy framework was clear on the role and responsibility of the municipality in waste management; secondly, Enoch Mgijima Local Municipality had clearly articulated waste management policy and operational procedure; thirdly, in spite of robust municipal policy and procedures, the inadequate inputs and resources for waste management programme in Enoch Mgijima Local Municipality impacted negatively on service delivery in Whittlesea; fourthly, the challenges experienced by municipal managers in EMLM made it difficult for them to provide efficient waste management services to the Whittlesea community; and, finally the irresponsible attitude of the community in dumping waste worsened the provision of waste management in the municipality. , Thesis (MPA) -- Faculty of Management and Commerce, 2022
- Full Text:
- Date Issued: 2022-09
An investigation in waste management in Enoch Mgijima Local Municipality: a case study in Whittlesea
- Authors: Mngese, Bongani Elvis https://orcid.org/0000-0003-3222-0764
- Date: 2022-09
- Subjects: Refuse and refuse disposal -- Law and legislation -- South Africa , Local government -- Law and legislation -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/28784 , vital:74921
- Description: The study investigates the state of rendering waste service to Whittlesea within the Enoch Mgijima Local Municipality (EMLM). The study assesses into local municipality waste management policy and how the everyday attitude on waste handling has impacted on waste management. The study responds to the contextual gap in EMLM waste service delivery to Whittlesea community. The study addresses the following key research questions: What is the waste management policy in Enoch Mgijima Local Municipality? How was the waste management policy implemented by municipal mangers in Enoch Mgijima Local Municipality to Whittlesea? How did the community of Whittlesea respond to the waste management service delivery of Enoch Mgijima Local Municipality? The study used a qualitative approach, the data collection instruments included document review of policy and other official document, and in-depth interviews of respondents from the municipality and the community. The key findings of this research study were as follows- firstly, the national policy framework was clear on the role and responsibility of the municipality in waste management; secondly, Enoch Mgijima Local Municipality had clearly articulated waste management policy and operational procedure; thirdly, in spite of robust municipal policy and procedures, the inadequate inputs and resources for waste management programme in Enoch Mgijima Local Municipality impacted negatively on service delivery in Whittlesea; fourthly, the challenges experienced by municipal managers in EMLM made it difficult for them to provide efficient waste management services to the Whittlesea community; and, finally the irresponsible attitude of the community in dumping waste worsened the provision of waste management in the municipality. , Thesis (MPA) -- Faculty of Management and Commerce, 2022
- Full Text:
- Date Issued: 2022-09
Analysis of early-phase contact tracing during the coronavirus disease 2019 outbreak in Mangaung Metro, Free State
- Monyobo, Priscilla Kesaletseng
- Authors: Monyobo, Priscilla Kesaletseng
- Date: 2022-09
- Subjects: COVID-19 (Disease) , Contact tracing (Epidemiology) , Public health
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23533 , vital:58105
- Description: Background and Aim Contact tracing is a critical public health measure for controlling and preventing the spread of infectious diseases. Although the principles underlying this strategy are not novel, understanding the changes in infectiousness of COVID-19 is indeed novel. As are the capacity and operating procedures required to support disease investigation in Mangang Metro during the SARS-CoV-2 (COVID-19) pandemic. On 16 March 2020, the first coronavirus disease case in the area, which led to a larger outbreak, occurred in Mangaung Metro, Free State province, South Africa. To date, Mangaung Metro remains the epicentre of the COVID-19 pandemic and the primary driver of the caseload in the Free State province. The aim of this study was to analyse contact tracing data in Mangaung Metro during the early phase of the COVID-19 outbreak (16 March 2020 – 30 June 2020) in order to measure the viral transmissibility of COVID-19 in the early stages of the outbreak, specifically in the context of Mangaung Metro. Methods A descriptive systematic analysis of index COVID-19 cases and their contacts in Mangaung Metro was conducted. The review period ran from 16 March to 30 June 2020, during which there was a total of 1 001 cases in Mangaung Metro. Data was captured on an Excel spreadsheet using the contact line list variables from the established National Institute of Communicable Disease contact line list framework. The inferential statistics were based on a time series analysis to compare the impact of contact tracing stratified by symptomatology and the root cause of the cases to the overall cases in Mangaung Metro. The study determined whether isolation, quarantine, and contact tracing were able to control outbreaks in the early phase using characteristics of disease transmission and parameters particularised to the COVID- 19 pathogen. Results As of 30 June 2020, the Free State province had a total of 2 072 COVID-19 cases. Mangaung Metro contributed 1 001 cases (48percent) of the total number of cases in the study period. Between March and June 2020, 3 553 contacts were traced in Mangaung Metro. This number translates to at least three investigated and traced contacts per index or laboratory confirmed positive case. From the traced contacts, 1 080 samples were collected and sent for laboratory testing. In April 2020, the greatest number of samples were collected. This high rate in sample collection is posited to be the result of the high rate of contacts traced, as well as the initial clinical guidelines followed for contact tracing. Most positive contacts were discovered in March 2020. One of the possible reasons for the high detection of COVID-19 confirmed positive contacts during the early stages of the outbreak was the focus and importance of contact tracing while the caseload remained relatively low. However, as the outbreak progressed in the Mangaung Metro context, the number and relative percentage of positive cases detected through contact tracing decreased. In total, the positive contacts recorded in March 2020 amounted to 92 (51.3percent), 18 in April (10.5percent), 41 in May (22.9percent), and 28 in June (15.6percent). The March 2020 tracking rate was the highest at 73.2percent, with an average contact tracing rate of 15.5percentby the end of June 2020. Of all the contacts traced, 7.9percent involved healthcare workers in the Free State. Conclusion The study’s findings show that contact tracing was an effective control measure during the early stages of the COVID-19 outbreak in Mangung Metro district. Furthermore, the impact was greatest when the caseload was low and the burden on the healthcare system less severe. Mangaung Metro demonstrated the capability of tracing more contacts in the early-early phase of the outbreak; however, as the outbreak progressed to the latent early phase, the caseload increased and fewer contacts were traced. The consequence of contact tracing not being as effective during the latent early phase relates to the increase in both exposed and untraceable contacts, which in turn fueled the increase of new cases. This further impacted the at-risk and vulnerable population, especially the elderly, who were at an increased risk if not traced in a timely manner, possibly resulting in mortality. , Thesis (MPH) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Monyobo, Priscilla Kesaletseng
- Date: 2022-09
- Subjects: COVID-19 (Disease) , Contact tracing (Epidemiology) , Public health
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23533 , vital:58105
- Description: Background and Aim Contact tracing is a critical public health measure for controlling and preventing the spread of infectious diseases. Although the principles underlying this strategy are not novel, understanding the changes in infectiousness of COVID-19 is indeed novel. As are the capacity and operating procedures required to support disease investigation in Mangang Metro during the SARS-CoV-2 (COVID-19) pandemic. On 16 March 2020, the first coronavirus disease case in the area, which led to a larger outbreak, occurred in Mangaung Metro, Free State province, South Africa. To date, Mangaung Metro remains the epicentre of the COVID-19 pandemic and the primary driver of the caseload in the Free State province. The aim of this study was to analyse contact tracing data in Mangaung Metro during the early phase of the COVID-19 outbreak (16 March 2020 – 30 June 2020) in order to measure the viral transmissibility of COVID-19 in the early stages of the outbreak, specifically in the context of Mangaung Metro. Methods A descriptive systematic analysis of index COVID-19 cases and their contacts in Mangaung Metro was conducted. The review period ran from 16 March to 30 June 2020, during which there was a total of 1 001 cases in Mangaung Metro. Data was captured on an Excel spreadsheet using the contact line list variables from the established National Institute of Communicable Disease contact line list framework. The inferential statistics were based on a time series analysis to compare the impact of contact tracing stratified by symptomatology and the root cause of the cases to the overall cases in Mangaung Metro. The study determined whether isolation, quarantine, and contact tracing were able to control outbreaks in the early phase using characteristics of disease transmission and parameters particularised to the COVID- 19 pathogen. Results As of 30 June 2020, the Free State province had a total of 2 072 COVID-19 cases. Mangaung Metro contributed 1 001 cases (48percent) of the total number of cases in the study period. Between March and June 2020, 3 553 contacts were traced in Mangaung Metro. This number translates to at least three investigated and traced contacts per index or laboratory confirmed positive case. From the traced contacts, 1 080 samples were collected and sent for laboratory testing. In April 2020, the greatest number of samples were collected. This high rate in sample collection is posited to be the result of the high rate of contacts traced, as well as the initial clinical guidelines followed for contact tracing. Most positive contacts were discovered in March 2020. One of the possible reasons for the high detection of COVID-19 confirmed positive contacts during the early stages of the outbreak was the focus and importance of contact tracing while the caseload remained relatively low. However, as the outbreak progressed in the Mangaung Metro context, the number and relative percentage of positive cases detected through contact tracing decreased. In total, the positive contacts recorded in March 2020 amounted to 92 (51.3percent), 18 in April (10.5percent), 41 in May (22.9percent), and 28 in June (15.6percent). The March 2020 tracking rate was the highest at 73.2percent, with an average contact tracing rate of 15.5percentby the end of June 2020. Of all the contacts traced, 7.9percent involved healthcare workers in the Free State. Conclusion The study’s findings show that contact tracing was an effective control measure during the early stages of the COVID-19 outbreak in Mangung Metro district. Furthermore, the impact was greatest when the caseload was low and the burden on the healthcare system less severe. Mangaung Metro demonstrated the capability of tracing more contacts in the early-early phase of the outbreak; however, as the outbreak progressed to the latent early phase, the caseload increased and fewer contacts were traced. The consequence of contact tracing not being as effective during the latent early phase relates to the increase in both exposed and untraceable contacts, which in turn fueled the increase of new cases. This further impacted the at-risk and vulnerable population, especially the elderly, who were at an increased risk if not traced in a timely manner, possibly resulting in mortality. , Thesis (MPH) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
Analysis of early-phase contact tracing during the coronavirus disease 2019 outbreak in Mangaung Metro, Free State
- Monyobo, Priscilla Kesaletseng
- Authors: Monyobo, Priscilla Kesaletseng
- Date: 2022-09
- Subjects: Contact tracing (Epidemiology) , Health services administration
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27006 , vital:66215
- Description: Background and Aim Contact tracing is a critical public health measure for controlling and preventing the spread of infectious diseases. Although the principles underlying this strategy are not novel, understanding the changes in infectiousness of COVID-19 is indeed novel. As are the capacity and operating procedures required to support disease investigation in Mangang Metro during the SARS-CoV-2 (COVID-19) pandemic. On 16 March 2020, the first coronavirus disease case in the area, which led to a larger outbreak, occurred in Mangaung Metro, Free State province, South Africa. To date, Mangaung Metro remains the epicentre of the COVID-19 pandemic and the primary driver of the caseload in the Free State province. The aim of this study was to analyse contact tracing data in Mangaung Metro during the early phase of the COVID-19 outbreak (16 March 2020 – 30 June 2020) in order to measure the viral transmissibility of COVID-19 in the early stages of the outbreak, specifically in the context of Mangaung Metro. Methods A descriptive systematic analysis of index COVID-19 cases and their contacts in Mangaung Metro was conducted. The review period ran from 16 March to 30 June 2020, during which there was a total of 1 001 cases in Mangaung Metro. Data was captured on an Excel spreadsheet using the contact line list variables from the established National Institute of Communicable Disease contact line list framework. The inferential statistics were based on a time series analysis to compare the impact of contact tracing stratified by symptomatology and the root cause of the cases to the overall cases in Mangaung Metro. The study determined whether isolation, quarantine, and contact tracing were able to control outbreaks in the early phase using characteristics of disease transmission and parameters particularised to the COVID- 19 pathogen. Results As of 30 June 2020, the Free State province had a total of 2 072 COVID-19 cases. Mangaung Metro contributed 1 001 cases (48 percent) of the total number of cases in the study period. Between March and June 2020, 3 553 contacts were traced in Mangaung Metro. This number translates to at least three investigated and traced contacts per index or laboratory confirmed positive case. From the traced contacts, 1 080 samples were collected and sent for laboratory testing. In April 2020, the greatest number of samples were collected. This high rate in sample collection is posited to be the result of the high rate of contacts traced, as well as the initial clinical guidelines followed for contact tracing. Most positive contacts were discovered in March 2020. One of the possible reasons for the high detection of COVID-19 confirmed positive contacts during the early stages of the outbreak was the focus and importance of contact tracing while the caseload remained relatively low. However, as the outbreak progressed in the Mangaung Metro context, the number and relative percentage of positive cases detected through contact tracing decreased. In total, the positive contacts recorded in March 2020 amounted to 92 (51.3 percent), 18 in April (10.5 percent), 41 in May (22.9percent), and 28 in June (15.6 percent). The March 2020 tracking rate was the highest at 73.2percent, with an average contact tracing rate of 15.5 percent by the end of June 2020. Of all the contacts traced, 7.9 percent involved healthcare workers in the Free State. Conclusion The study’s findings show that contact tracing was an effective control measure during the early stages of the COVID-19 outbreak in Mangung Metro district. Furthermore, the impact was greatest when the caseload was low and the burden on the healthcare system less severe. Mangaung Metro demonstrated the capability of tracing more contacts in the early-early phase of the outbreak; however, as the outbreak progressed to the latent early phase, the caseload increased and fewer contacts were traced. The consequence of contact tracing not being as effective during the latent early phase relates to the increase in both exposed and untraceable contacts, which in turn fueled the increase of new cases. This further impacted the at-risk and vulnerable population, especially the elderly, who were at an increased risk if not traced in a timely manner, possibly resulting in mortality. , Thesis (MPA) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Monyobo, Priscilla Kesaletseng
- Date: 2022-09
- Subjects: Contact tracing (Epidemiology) , Health services administration
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27006 , vital:66215
- Description: Background and Aim Contact tracing is a critical public health measure for controlling and preventing the spread of infectious diseases. Although the principles underlying this strategy are not novel, understanding the changes in infectiousness of COVID-19 is indeed novel. As are the capacity and operating procedures required to support disease investigation in Mangang Metro during the SARS-CoV-2 (COVID-19) pandemic. On 16 March 2020, the first coronavirus disease case in the area, which led to a larger outbreak, occurred in Mangaung Metro, Free State province, South Africa. To date, Mangaung Metro remains the epicentre of the COVID-19 pandemic and the primary driver of the caseload in the Free State province. The aim of this study was to analyse contact tracing data in Mangaung Metro during the early phase of the COVID-19 outbreak (16 March 2020 – 30 June 2020) in order to measure the viral transmissibility of COVID-19 in the early stages of the outbreak, specifically in the context of Mangaung Metro. Methods A descriptive systematic analysis of index COVID-19 cases and their contacts in Mangaung Metro was conducted. The review period ran from 16 March to 30 June 2020, during which there was a total of 1 001 cases in Mangaung Metro. Data was captured on an Excel spreadsheet using the contact line list variables from the established National Institute of Communicable Disease contact line list framework. The inferential statistics were based on a time series analysis to compare the impact of contact tracing stratified by symptomatology and the root cause of the cases to the overall cases in Mangaung Metro. The study determined whether isolation, quarantine, and contact tracing were able to control outbreaks in the early phase using characteristics of disease transmission and parameters particularised to the COVID- 19 pathogen. Results As of 30 June 2020, the Free State province had a total of 2 072 COVID-19 cases. Mangaung Metro contributed 1 001 cases (48 percent) of the total number of cases in the study period. Between March and June 2020, 3 553 contacts were traced in Mangaung Metro. This number translates to at least three investigated and traced contacts per index or laboratory confirmed positive case. From the traced contacts, 1 080 samples were collected and sent for laboratory testing. In April 2020, the greatest number of samples were collected. This high rate in sample collection is posited to be the result of the high rate of contacts traced, as well as the initial clinical guidelines followed for contact tracing. Most positive contacts were discovered in March 2020. One of the possible reasons for the high detection of COVID-19 confirmed positive contacts during the early stages of the outbreak was the focus and importance of contact tracing while the caseload remained relatively low. However, as the outbreak progressed in the Mangaung Metro context, the number and relative percentage of positive cases detected through contact tracing decreased. In total, the positive contacts recorded in March 2020 amounted to 92 (51.3 percent), 18 in April (10.5 percent), 41 in May (22.9percent), and 28 in June (15.6 percent). The March 2020 tracking rate was the highest at 73.2percent, with an average contact tracing rate of 15.5 percent by the end of June 2020. Of all the contacts traced, 7.9 percent involved healthcare workers in the Free State. Conclusion The study’s findings show that contact tracing was an effective control measure during the early stages of the COVID-19 outbreak in Mangung Metro district. Furthermore, the impact was greatest when the caseload was low and the burden on the healthcare system less severe. Mangaung Metro demonstrated the capability of tracing more contacts in the early-early phase of the outbreak; however, as the outbreak progressed to the latent early phase, the caseload increased and fewer contacts were traced. The consequence of contact tracing not being as effective during the latent early phase relates to the increase in both exposed and untraceable contacts, which in turn fueled the increase of new cases. This further impacted the at-risk and vulnerable population, especially the elderly, who were at an increased risk if not traced in a timely manner, possibly resulting in mortality. , Thesis (MPA) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
Clinical governance implementation challenges in the Department of Health, Mpumalanga, South Africa
- Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Authors: Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Date: 2022-09
- Subjects: Clinical competence , Health services administration
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27275 , vital:66532
- Description: Clinical governance (CG) is the system through which health authorities are accountable for continuously improving the quality of their services and safeguarding high standards of care by creating an environment in which clinical excellence flourishes. South Africa is one of the countries where CG has not been successfully implemented. This study sought to explore the CG implementation challenges in the Mpumalanga province, South Africa. The study objectives included the seven pillars of CG. The study was a qualitative and exploratory, using purposive sampling technique to select study participants. A total of twenty-two (22) individuals were selected for the study. Semi-structured interviews were used for data collection. Each interview was transcribed verbatim by the researcher. Confidentiality was ensured through the coding of interviewee names. The content analysis technique was used for data analysis, using the study objectives as themes. The study found general lack of understanding of the concept of CG, poor performance of clinical audits, sub-standard clinical performance and effectiveness, poor clinical risk management, poor patient and public involvement in patient care, lack of evidence-based practice and research, inadequate training and development of healthcare workers, and sub-standard health information management across the department. The researcher recommends that the CG policy be prioritised by the Mpumalanga DOH, that systems be put in place to facilitate policy implementation, and that the departmental staff establishments at all levels, prioritise healthcare professionals in key leadership positions. In conclusion, there are numerous challenges that confront the Mpumalanga Department of Health regarding the implementation of clinical governance, requiring urgent attention. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Date: 2022-09
- Subjects: Clinical competence , Health services administration
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27275 , vital:66532
- Description: Clinical governance (CG) is the system through which health authorities are accountable for continuously improving the quality of their services and safeguarding high standards of care by creating an environment in which clinical excellence flourishes. South Africa is one of the countries where CG has not been successfully implemented. This study sought to explore the CG implementation challenges in the Mpumalanga province, South Africa. The study objectives included the seven pillars of CG. The study was a qualitative and exploratory, using purposive sampling technique to select study participants. A total of twenty-two (22) individuals were selected for the study. Semi-structured interviews were used for data collection. Each interview was transcribed verbatim by the researcher. Confidentiality was ensured through the coding of interviewee names. The content analysis technique was used for data analysis, using the study objectives as themes. The study found general lack of understanding of the concept of CG, poor performance of clinical audits, sub-standard clinical performance and effectiveness, poor clinical risk management, poor patient and public involvement in patient care, lack of evidence-based practice and research, inadequate training and development of healthcare workers, and sub-standard health information management across the department. The researcher recommends that the CG policy be prioritised by the Mpumalanga DOH, that systems be put in place to facilitate policy implementation, and that the departmental staff establishments at all levels, prioritise healthcare professionals in key leadership positions. In conclusion, there are numerous challenges that confront the Mpumalanga Department of Health regarding the implementation of clinical governance, requiring urgent attention. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
Clinical governance implementation challenges in the Department of Health, Mpumalanga, South Africa
- Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Authors: Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Date: 2022-09
- Subjects: Clinical competence , Evidence-based medicine , Health services administration
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23600 , vital:58194
- Description: Clinical governance (CG) is the system through which health authorities are accountable for continuously improving the quality of their services and safeguarding high standards of care by creating an environment in which clinical excellence flourishes. South Africa is one of the countries where CG has not been successfully implemented. This study sought to explore the CG implementation challenges in the Mpumalanga province, South Africa. The study objectives included the seven pillars of CG. The study was a qualitative and exploratory, using purposive sampling technique to select study participants. A total of twenty-two (22) individuals were selected for the study. Semi-structured interviews were used for data collection. Each interview was transcribed verbatim by the researcher. Confidentiality was ensured through the coding of interviewee names. The content analysis technique was used for data analysis, using the study objectives as themes. The study found general lack of understanding of the concept of CG, poor performance of clinical audits, sub-standard clinical performance and effectiveness, poor clinical risk management, poor patient and public involvement in patient care, lack of evidence-based practice and research, inadequate training and development of healthcare workers, and sub-standard health information management across the department. The researcher recommends that the CG policy be prioritised by the Mpumalanga DOH, that systems be put in place to facilitate policy implementation, and that the departmental staff establishments at all levels, prioritise healthcare professionals in key leadership positions. In conclusion, there are numerous challenges that confront the Mpumalanga Department of Health regarding the implementation of clinical governance, requiring urgent attention. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
- Date: 2022-09
- Subjects: Clinical competence , Evidence-based medicine , Health services administration
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23600 , vital:58194
- Description: Clinical governance (CG) is the system through which health authorities are accountable for continuously improving the quality of their services and safeguarding high standards of care by creating an environment in which clinical excellence flourishes. South Africa is one of the countries where CG has not been successfully implemented. This study sought to explore the CG implementation challenges in the Mpumalanga province, South Africa. The study objectives included the seven pillars of CG. The study was a qualitative and exploratory, using purposive sampling technique to select study participants. A total of twenty-two (22) individuals were selected for the study. Semi-structured interviews were used for data collection. Each interview was transcribed verbatim by the researcher. Confidentiality was ensured through the coding of interviewee names. The content analysis technique was used for data analysis, using the study objectives as themes. The study found general lack of understanding of the concept of CG, poor performance of clinical audits, sub-standard clinical performance and effectiveness, poor clinical risk management, poor patient and public involvement in patient care, lack of evidence-based practice and research, inadequate training and development of healthcare workers, and sub-standard health information management across the department. The researcher recommends that the CG policy be prioritised by the Mpumalanga DOH, that systems be put in place to facilitate policy implementation, and that the departmental staff establishments at all levels, prioritise healthcare professionals in key leadership positions. In conclusion, there are numerous challenges that confront the Mpumalanga Department of Health regarding the implementation of clinical governance, requiring urgent attention. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-09
Consumerism, authenticity and African communalism
- Smook, E https://orcid.org/0000-0003-4226-6029
- Authors: Smook, E https://orcid.org/0000-0003-4226-6029
- Date: 2022-09
- Subjects: Consumption (Economics) , Authenticity (Philosophy) , Philosophy, African
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23958 , vital:62022
- Description: Let me state, from the outset, that the issues raised below may be considered from various vantage points – Capitalism, Marxism, etc. However, this thesis is an endeavour to account for the loss of authenticity due to the most salient features of the consumer paradigm, which is the manufactured object, the production line and the proliferation of said objects. True relationships, or shall we say authentic dialogue, is based upon a difference of viewpoints – or epistemic distance – between the interlocutors. This difference of opinion, it may be argued, allows for a cognitive jostling between the subjects involved and represents, as it were, the reciprocal back and forth movement of ideas that betokens actively engaged dialogue. Crucial, then, to true, and by extension authentic, relationships is an epistemic distance steeped in variegated, heterogeneous points of view. For it is in sharing the differences in our points of view or interpretations of the world that we may start a dialogue far removed from each other and then sustain said dialogue in an attempt to reconcile our differences. The continuation of the dialogue, then, depends upon difference. Without the latter difference, the conditions of true dialogue, which is also a marker of authentic relationships, the need for sustained debate is forfeited and the dialogue ceases to serve a purpose – for the subjects involved in the intellectual jostling and exchange of ideas may already anticipate the thoughts of the other. In so anticipating the thoughts of the other, what is brought to the fore is not the ideas of the other, and by extension the other’s existence distinct from mine, but rather my own existence and thoughts. Were I and the other to share a constellation of beliefs, I am left with only that which I already believe in and so only with my own thoughts. The other’s differing opinion is crucial to their appearing to me as an element discreet and distinct from me. For if the other’s being is in essence of the same ilk as mine – and with that I mean if the other’s points of view and adopted systems of praxis mirror mine – we are like trees in a forest. The existence of collective nouns attests to this latter remark; we are prone to see the forest, not the similar trees that constitute it. Now the question arises as to the constitution of the self; what is it that makes up the character and nature of a person and how, if at all, may subjects be said to differ epistemically? According to Sartre, the ego is a transcendent object for consciousness, meaning that it exists out there in the world just like other objects. This is the case because consciousness is essentially empty. Recall Sartre’s famous claim that existence precedes essence, which in turn means that consciousness, or the ego, is filled up inchmeal with contents outside itself. In other words, that with which we are engaged constitutes the contents of consciousness. Repeated exposure to certain objects, or phenomena, brings about the cultivation of states and qualities – these, as it were, constituting the ego in the end. Moreover, these states and qualities, as arisen from repeated exposure to like phenomena, will instil in the subject a certain proclivity for a certain manner of action under specific conditions. As such, having been presented with something disagreeable many times over, a state of repulsion might gain a foothold in my ego regarding the phenomenon in question. This in turn will dictate how I act in the presence of said phenomenon or any other phenomena that include, adumbrationally, some of the qualities of the original phenomenon. As such, then, my actions are reflections of the states that I experience in the presence of certain objects or phenomena and, it may be argued, reflexively represent the world around me as that which constitutes my ego. The facticity of the world, then, has a great bearing upon the manner in which I perceive and engage the world. However, claims Sartre, facticity is but one side of the coin. The world and its meaning are constituted by what Sartre calls brute meaning. This refers to the fact that meaning is a matter of public opinion and does not precede the phenomenon or object itself – the latter being, in essence, but a bare, pliable, monstrous mass of being-in-itself. Due to this occurrence of meaning being man made, we are in a unique position of freedom. We are, he further claims, capable of transcending these brute meanings, enabling us to avail ourselves of the objects or phenomena in question in a bespoke manner. Freedom to choose how we interact with and interpret the world is thus the ontological ground of choice. We have, on the one side, the world in its undifferentiated state – being-in-itself – and on the other the possibility to give this world a specific meaning in accordance with our intentions – being-for-itself. Freedom to choose, so construed, thus ontologically underlies the very fabric of our existence, hence the claim that we are condemned to be free. Choosing whether to continue along the path set out by our original factual condition or to transcend it and make of it something different altogether is thus not a choice at all, but the obligatory condition of the human condition. Once again, this is the case because consciousness, as per Sartre, is empty to start with and can only be filled with the contents of phenomena or objects in accordance with our intentional engagement of them. However, Sartre continues, this freedom of meaning and the fact that brute existents represent nothing more than the convergence of publicly ascribed meaning awaken in the subject a certain nausea – a nausea born of the fact that we, the people, are at every junction in a position where we have to choose the meaning of life. Determinism, thusly, does not exist and we are not only free to choose the meanings of our own lives, but are responsible for what our lives become. This realisation proves to be too much for most to stomach and leads them along a specific path of choice: over-identification with either their factual realities or with the possibility to transcend the latter. Either way, what they aim to achieve with this overidentification is the suppression of the nauseating reality that reality is nought but what we make it to be and we are thus responsible for what it becomes. Sartre calls this bad faith. Pandering to this proclivity towards bad faith, or alternatively, the propensity for overidentification with either side on the facticity/transcendence dichotomy, we find consumerism. The consumer paradigm delineates happiness as an objective ideal, attainable through the acquisition of specific markers of demonstrable happiness. At the same time, it also provides an answer to the nauseating reality that we, humans, are never fully determined beings, but find ourselves vacillating between our factual constraints and our transcendences thereof. It offers us the crystalised means of becoming this or that individual by way of populating our immediate and personal surroundings with signifiers of happiness. Considering, moreover, that a liberalist conception of human being clearly indicates that individuation of each subject is an important aspect of existence, authenticity in terms of rights emerge as a corollary of said individuation. Each individual, so construed, is given the opportunity, the right, to acquire said markers of happiness and individuation. Obtaining these, it may be argued, allows the individual two things: firstly, to quell the nausea that haunts our dualistic lives by concretising it altogether and so doing highlighting the factual side of things; and secondly, to become discreet and individuated subjects, authentic in their beings. However, the authenticity so begotten provides nought but a thin veneer of idiosyncrasy, as the markers of said authenticity are publicly available and so the same for everyone. The problem, thus, of self-individuation is resolved by providing the subject the means of over-identification with their factual realities whilst convincing them, the consumers, that the objects on offer will afford them a degree of happiness and set them apart from their fellow subjects. The unfortunate upshot of this is that subjects all avail themselves of the same set of objects in an attempt to quell the nausea that besets the individual plunged into an undifferentiated existence. We are here at the heart of the matter. Due to the proliferation of like objects throughout the life-world, a specific system of praxis is implied. So as to navigate the life-world and utilise the similar objects that populate it, consumers are driven towards shared ideologies and courses of action. Moreover, their intentions also converge, as they all seek to establish a web of objects around them that would bespeak their individuation and happiness. Where the life-world has become such a homogeneous landscape, it may be argued, in line with Sartrean thought, that the contents of consciousness would also be similar for all. And where the contents of consciousness is similar for all, we may argue that reasoning would be similar for all. It is at this point that dialogue breaks down, for there is nothing epistemically to separate interlocutors and therefore no differences of opinion to sustain true dialogue. If, as it was reasoned some pages prior, it is the case that sustained dialogue provides the predicate upon which authentic relationships are to be based, the collapse of this epistemic distance between consumers must then also lead to a collapse of authentic relationships. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Smook, E https://orcid.org/0000-0003-4226-6029
- Date: 2022-09
- Subjects: Consumption (Economics) , Authenticity (Philosophy) , Philosophy, African
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23958 , vital:62022
- Description: Let me state, from the outset, that the issues raised below may be considered from various vantage points – Capitalism, Marxism, etc. However, this thesis is an endeavour to account for the loss of authenticity due to the most salient features of the consumer paradigm, which is the manufactured object, the production line and the proliferation of said objects. True relationships, or shall we say authentic dialogue, is based upon a difference of viewpoints – or epistemic distance – between the interlocutors. This difference of opinion, it may be argued, allows for a cognitive jostling between the subjects involved and represents, as it were, the reciprocal back and forth movement of ideas that betokens actively engaged dialogue. Crucial, then, to true, and by extension authentic, relationships is an epistemic distance steeped in variegated, heterogeneous points of view. For it is in sharing the differences in our points of view or interpretations of the world that we may start a dialogue far removed from each other and then sustain said dialogue in an attempt to reconcile our differences. The continuation of the dialogue, then, depends upon difference. Without the latter difference, the conditions of true dialogue, which is also a marker of authentic relationships, the need for sustained debate is forfeited and the dialogue ceases to serve a purpose – for the subjects involved in the intellectual jostling and exchange of ideas may already anticipate the thoughts of the other. In so anticipating the thoughts of the other, what is brought to the fore is not the ideas of the other, and by extension the other’s existence distinct from mine, but rather my own existence and thoughts. Were I and the other to share a constellation of beliefs, I am left with only that which I already believe in and so only with my own thoughts. The other’s differing opinion is crucial to their appearing to me as an element discreet and distinct from me. For if the other’s being is in essence of the same ilk as mine – and with that I mean if the other’s points of view and adopted systems of praxis mirror mine – we are like trees in a forest. The existence of collective nouns attests to this latter remark; we are prone to see the forest, not the similar trees that constitute it. Now the question arises as to the constitution of the self; what is it that makes up the character and nature of a person and how, if at all, may subjects be said to differ epistemically? According to Sartre, the ego is a transcendent object for consciousness, meaning that it exists out there in the world just like other objects. This is the case because consciousness is essentially empty. Recall Sartre’s famous claim that existence precedes essence, which in turn means that consciousness, or the ego, is filled up inchmeal with contents outside itself. In other words, that with which we are engaged constitutes the contents of consciousness. Repeated exposure to certain objects, or phenomena, brings about the cultivation of states and qualities – these, as it were, constituting the ego in the end. Moreover, these states and qualities, as arisen from repeated exposure to like phenomena, will instil in the subject a certain proclivity for a certain manner of action under specific conditions. As such, having been presented with something disagreeable many times over, a state of repulsion might gain a foothold in my ego regarding the phenomenon in question. This in turn will dictate how I act in the presence of said phenomenon or any other phenomena that include, adumbrationally, some of the qualities of the original phenomenon. As such, then, my actions are reflections of the states that I experience in the presence of certain objects or phenomena and, it may be argued, reflexively represent the world around me as that which constitutes my ego. The facticity of the world, then, has a great bearing upon the manner in which I perceive and engage the world. However, claims Sartre, facticity is but one side of the coin. The world and its meaning are constituted by what Sartre calls brute meaning. This refers to the fact that meaning is a matter of public opinion and does not precede the phenomenon or object itself – the latter being, in essence, but a bare, pliable, monstrous mass of being-in-itself. Due to this occurrence of meaning being man made, we are in a unique position of freedom. We are, he further claims, capable of transcending these brute meanings, enabling us to avail ourselves of the objects or phenomena in question in a bespoke manner. Freedom to choose how we interact with and interpret the world is thus the ontological ground of choice. We have, on the one side, the world in its undifferentiated state – being-in-itself – and on the other the possibility to give this world a specific meaning in accordance with our intentions – being-for-itself. Freedom to choose, so construed, thus ontologically underlies the very fabric of our existence, hence the claim that we are condemned to be free. Choosing whether to continue along the path set out by our original factual condition or to transcend it and make of it something different altogether is thus not a choice at all, but the obligatory condition of the human condition. Once again, this is the case because consciousness, as per Sartre, is empty to start with and can only be filled with the contents of phenomena or objects in accordance with our intentional engagement of them. However, Sartre continues, this freedom of meaning and the fact that brute existents represent nothing more than the convergence of publicly ascribed meaning awaken in the subject a certain nausea – a nausea born of the fact that we, the people, are at every junction in a position where we have to choose the meaning of life. Determinism, thusly, does not exist and we are not only free to choose the meanings of our own lives, but are responsible for what our lives become. This realisation proves to be too much for most to stomach and leads them along a specific path of choice: over-identification with either their factual realities or with the possibility to transcend the latter. Either way, what they aim to achieve with this overidentification is the suppression of the nauseating reality that reality is nought but what we make it to be and we are thus responsible for what it becomes. Sartre calls this bad faith. Pandering to this proclivity towards bad faith, or alternatively, the propensity for overidentification with either side on the facticity/transcendence dichotomy, we find consumerism. The consumer paradigm delineates happiness as an objective ideal, attainable through the acquisition of specific markers of demonstrable happiness. At the same time, it also provides an answer to the nauseating reality that we, humans, are never fully determined beings, but find ourselves vacillating between our factual constraints and our transcendences thereof. It offers us the crystalised means of becoming this or that individual by way of populating our immediate and personal surroundings with signifiers of happiness. Considering, moreover, that a liberalist conception of human being clearly indicates that individuation of each subject is an important aspect of existence, authenticity in terms of rights emerge as a corollary of said individuation. Each individual, so construed, is given the opportunity, the right, to acquire said markers of happiness and individuation. Obtaining these, it may be argued, allows the individual two things: firstly, to quell the nausea that haunts our dualistic lives by concretising it altogether and so doing highlighting the factual side of things; and secondly, to become discreet and individuated subjects, authentic in their beings. However, the authenticity so begotten provides nought but a thin veneer of idiosyncrasy, as the markers of said authenticity are publicly available and so the same for everyone. The problem, thus, of self-individuation is resolved by providing the subject the means of over-identification with their factual realities whilst convincing them, the consumers, that the objects on offer will afford them a degree of happiness and set them apart from their fellow subjects. The unfortunate upshot of this is that subjects all avail themselves of the same set of objects in an attempt to quell the nausea that besets the individual plunged into an undifferentiated existence. We are here at the heart of the matter. Due to the proliferation of like objects throughout the life-world, a specific system of praxis is implied. So as to navigate the life-world and utilise the similar objects that populate it, consumers are driven towards shared ideologies and courses of action. Moreover, their intentions also converge, as they all seek to establish a web of objects around them that would bespeak their individuation and happiness. Where the life-world has become such a homogeneous landscape, it may be argued, in line with Sartrean thought, that the contents of consciousness would also be similar for all. And where the contents of consciousness is similar for all, we may argue that reasoning would be similar for all. It is at this point that dialogue breaks down, for there is nothing epistemically to separate interlocutors and therefore no differences of opinion to sustain true dialogue. If, as it was reasoned some pages prior, it is the case that sustained dialogue provides the predicate upon which authentic relationships are to be based, the collapse of this epistemic distance between consumers must then also lead to a collapse of authentic relationships. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
Data management and dispensary: missing link contributing to antiretroviral loss to follow-Up in Lejweleputswa District
- Moatlhodi, Charlotte Motshele
- Authors: Moatlhodi, Charlotte Motshele
- Date: 2022-09
- Subjects: Health services administration , Drug monitoring , Antiretroviral agents
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26973 , vital:66207
- Description: Background and aim: The widespread use and access to Anti-Retro Viral Treatment (ART) world-wide has contributed to full preventive and therapeutic benefits. An estimated amount of 68percent of HIV positive people received ART in South Africa (SA) as of 2018. However, reports from TIER.Net and DHIS (District Health Information System), indicate that the retention of patients on ART (specifically first line triple combination therapy Tenofovir Emtricitabine Efavirenz (TEE)) continues to decline. Meanwhile, data on TEE dispensed from the dispensary shows increasing quantities patients across the Free State province on a monthly basis. The aim of this study is to determine factors contributing to the discrepancy between Fixed Dose Combination (FDC) TEE dispensing data and patients on FDC TEE captured on TIER.Net and Health Patient Registration System (HPRS), as a means of improving identification and monitoring of patients that carry the potential risk of being lost to subsequent follow-ups (ART collection / clinical visits). Methods: A retrospective, quantitative, and descriptive record review of 382 medical records of HIV positive patients, along with TIER.Net and Health Patient Registration System (HPRS) reports, was conducted at five primary healthcare (PHC) facilities, each representing the five sub-districts found in Lejweleputswa district using a self-designed data collection tool. Descriptive statistics was used to summarise and present data. Results: Sixty five percent the TEE collected from the dispensary was captured on TIER. Net. It could not be determined on none of the medical records whether or not the administrative clerk captured dispensed TEE on the same date of collection from the dispensary on TIER.Net. Subsequently, the actual date of capturing the TEE dispenses on TIER.Net following collection of the treatment from the dispensary could also not be determined. The overall data on TEE dispensed/collected from the dispensary the same was not the same as the data captured on TIER.Net. Thirty five percent of patients were reported to have collected their ART according to dispensary data than that reported on TIER.Net. Eighty percent of the TEE collected from the dispensary was captured on HPRS. Eighty percent of facilities had an area and computer dedicated for HPRS and TIER.Net but none had a backup computer in cases of theft/breakage. None of the facilities had access to back up connectivity, a manual capturing process in the form of paper-based head count registers was instead utilised as back-up. Conclusion: The following factors were found to contribute to the discrepancy between the TEE dispensing data, TIER.net and HPRS: Poor records keeping, unauthorised dispensing of prescriptions, poor data management, delays and non-capturing of ART medical records and infrastructural and human resource challenges that exist in the data management of the patient medical records. There is a need to address these gaps in order to improve reliability of dispensary data, as well as reports from TIER.Net and HPRS, in order to streamline the identification and monitoring of patients at risk of becoming lost to follow-up. , Thesis (MPA) -- Faculty of Health Sciences
- Full Text:
- Date Issued: 2022-09
- Authors: Moatlhodi, Charlotte Motshele
- Date: 2022-09
- Subjects: Health services administration , Drug monitoring , Antiretroviral agents
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26973 , vital:66207
- Description: Background and aim: The widespread use and access to Anti-Retro Viral Treatment (ART) world-wide has contributed to full preventive and therapeutic benefits. An estimated amount of 68percent of HIV positive people received ART in South Africa (SA) as of 2018. However, reports from TIER.Net and DHIS (District Health Information System), indicate that the retention of patients on ART (specifically first line triple combination therapy Tenofovir Emtricitabine Efavirenz (TEE)) continues to decline. Meanwhile, data on TEE dispensed from the dispensary shows increasing quantities patients across the Free State province on a monthly basis. The aim of this study is to determine factors contributing to the discrepancy between Fixed Dose Combination (FDC) TEE dispensing data and patients on FDC TEE captured on TIER.Net and Health Patient Registration System (HPRS), as a means of improving identification and monitoring of patients that carry the potential risk of being lost to subsequent follow-ups (ART collection / clinical visits). Methods: A retrospective, quantitative, and descriptive record review of 382 medical records of HIV positive patients, along with TIER.Net and Health Patient Registration System (HPRS) reports, was conducted at five primary healthcare (PHC) facilities, each representing the five sub-districts found in Lejweleputswa district using a self-designed data collection tool. Descriptive statistics was used to summarise and present data. Results: Sixty five percent the TEE collected from the dispensary was captured on TIER. Net. It could not be determined on none of the medical records whether or not the administrative clerk captured dispensed TEE on the same date of collection from the dispensary on TIER.Net. Subsequently, the actual date of capturing the TEE dispenses on TIER.Net following collection of the treatment from the dispensary could also not be determined. The overall data on TEE dispensed/collected from the dispensary the same was not the same as the data captured on TIER.Net. Thirty five percent of patients were reported to have collected their ART according to dispensary data than that reported on TIER.Net. Eighty percent of the TEE collected from the dispensary was captured on HPRS. Eighty percent of facilities had an area and computer dedicated for HPRS and TIER.Net but none had a backup computer in cases of theft/breakage. None of the facilities had access to back up connectivity, a manual capturing process in the form of paper-based head count registers was instead utilised as back-up. Conclusion: The following factors were found to contribute to the discrepancy between the TEE dispensing data, TIER.net and HPRS: Poor records keeping, unauthorised dispensing of prescriptions, poor data management, delays and non-capturing of ART medical records and infrastructural and human resource challenges that exist in the data management of the patient medical records. There is a need to address these gaps in order to improve reliability of dispensary data, as well as reports from TIER.Net and HPRS, in order to streamline the identification and monitoring of patients at risk of becoming lost to follow-up. , Thesis (MPA) -- Faculty of Health Sciences
- Full Text:
- Date Issued: 2022-09
Exploring the perceptions and attitudes of University of Fort Hare students towards seeking psychological counselling services
- Authors: Pantshwa, Siziphiwe
- Date: 2022-09
- Subjects: Counseling , Helping behavior , Psychology, Applied
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23809 , vital:60807
- Description: The purpose of this study was to explore and examine the perceptions and attitudes of Fort Hare students towards seeking psychological help. It provided an understanding of factors that influence the help-seeking behaviours of university students. The study used an explorative qualitative approach in collecting data to find problems frequently encountered by students, their preferred sources of help for those problems, and their attitudes towards seeking psychological help. The sample was selected through a non-probability convenience sampling technique. Six participants, undergraduate and post-graduate students from the University of Fort Hare, East London campus, participated in the study. The data was collected in face-to-face semi-structured individual interviews in which participants were questioned orally. The interviews were recorded and transcribed verbatim. Data collected from the semi-structured interviews were thematically analysed by employing Braun and Clarke’s six steps of thematic analysis. Social constructionism as a meta-theory and Ecosystems theory provided the theoretical underpinning for the interpretation of the study. The study results revealed that close friends and family members were the preferred sources of help chosen by students. Five significant problems were experienced by students. Financial issues, difficulty adjusting to the university environment, academic stress, being away from home and managing time were at the top list of the challenges experienced by students. The factors that inhibited -seeking for psychological help were social stigma, access to a psychologist, financial constraints, and viewing a psychologist as a stranger. However the study further found that students had a positive attitude toward professional psychological help. This indicates a slight shift from previous studies, which reported negative attitudes among university students. Participants also reported on the influence of their socio-cultural background, the opinions held by their family and community members towards seeking psychological help. This study recommends specific interventions in which seeking psychological help can be reinforced, such as holding workshops to psycho-educate students about the benefits of using counselling services and the negative implications of not seeking professional help when experiencing psychological distress. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Pantshwa, Siziphiwe
- Date: 2022-09
- Subjects: Counseling , Helping behavior , Psychology, Applied
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23809 , vital:60807
- Description: The purpose of this study was to explore and examine the perceptions and attitudes of Fort Hare students towards seeking psychological help. It provided an understanding of factors that influence the help-seeking behaviours of university students. The study used an explorative qualitative approach in collecting data to find problems frequently encountered by students, their preferred sources of help for those problems, and their attitudes towards seeking psychological help. The sample was selected through a non-probability convenience sampling technique. Six participants, undergraduate and post-graduate students from the University of Fort Hare, East London campus, participated in the study. The data was collected in face-to-face semi-structured individual interviews in which participants were questioned orally. The interviews were recorded and transcribed verbatim. Data collected from the semi-structured interviews were thematically analysed by employing Braun and Clarke’s six steps of thematic analysis. Social constructionism as a meta-theory and Ecosystems theory provided the theoretical underpinning for the interpretation of the study. The study results revealed that close friends and family members were the preferred sources of help chosen by students. Five significant problems were experienced by students. Financial issues, difficulty adjusting to the university environment, academic stress, being away from home and managing time were at the top list of the challenges experienced by students. The factors that inhibited -seeking for psychological help were social stigma, access to a psychologist, financial constraints, and viewing a psychologist as a stranger. However the study further found that students had a positive attitude toward professional psychological help. This indicates a slight shift from previous studies, which reported negative attitudes among university students. Participants also reported on the influence of their socio-cultural background, the opinions held by their family and community members towards seeking psychological help. This study recommends specific interventions in which seeking psychological help can be reinforced, such as holding workshops to psycho-educate students about the benefits of using counselling services and the negative implications of not seeking professional help when experiencing psychological distress. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
Factors contributing to the speaking of English in Grade 4 literacy: Case studies of two schools in Chris Hani West District
- Authors: Kleinbooi, Cingile
- Date: 2022-09
- Subjects: English language -- Study and teaching , Language and languages -- Study and teaching , English teachers
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26018 , vital:64781
- Description: The teachers and the learners have difficulties using English as a medium of instruction. In the classroom lessons, IsiXhosa dominated natural dialogues across everybody in the class. There was minimal use of English. The findings revealed that some teachers and learners struggle to speak fluently in English as their second language. This led to mother tongue usage in many grade 4 classes that is isiXhosa. This triggered the researcher to embark on this study since both teachers and learners lack the motivation to speak English. This is because most teachers are not qualified. They are allowed to teach without the teaching qualifications due to a shortage of teaching staff and over-grounded learners. In this view, code-switching is one of the dominant factors in helping learners understand English instructions better. The study adopted a qualitative research approach. The interviews for the teachers, focus groups for the learners, and document analysis were used to collect data, whereby the purposive sampling technique was used to identify the participants. A case study approach was also adopted as the data was collected from schools. The inductive analysis was adopted for data analysis. The constructivism paradigm was also adopted since it uses the experiences of humans in their settings or circumstances. Classroom observations were also used to get in-depth information on the ground. The study recommends an extensive evaluation and review of the Language policy of South Africa to measure the effectiveness of English as a medium of instruction in public schools. , Thesis (MEd) -- Faculty of Education, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Kleinbooi, Cingile
- Date: 2022-09
- Subjects: English language -- Study and teaching , Language and languages -- Study and teaching , English teachers
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26018 , vital:64781
- Description: The teachers and the learners have difficulties using English as a medium of instruction. In the classroom lessons, IsiXhosa dominated natural dialogues across everybody in the class. There was minimal use of English. The findings revealed that some teachers and learners struggle to speak fluently in English as their second language. This led to mother tongue usage in many grade 4 classes that is isiXhosa. This triggered the researcher to embark on this study since both teachers and learners lack the motivation to speak English. This is because most teachers are not qualified. They are allowed to teach without the teaching qualifications due to a shortage of teaching staff and over-grounded learners. In this view, code-switching is one of the dominant factors in helping learners understand English instructions better. The study adopted a qualitative research approach. The interviews for the teachers, focus groups for the learners, and document analysis were used to collect data, whereby the purposive sampling technique was used to identify the participants. A case study approach was also adopted as the data was collected from schools. The inductive analysis was adopted for data analysis. The constructivism paradigm was also adopted since it uses the experiences of humans in their settings or circumstances. Classroom observations were also used to get in-depth information on the ground. The study recommends an extensive evaluation and review of the Language policy of South Africa to measure the effectiveness of English as a medium of instruction in public schools. , Thesis (MEd) -- Faculty of Education, 2022
- Full Text:
- Date Issued: 2022-09
Recidivism in children after completion of rhythm of life diversion programme in Chris Hani Eastern Cape
- Authors: Zimba, Thanduxolo
- Date: 2022-09
- Subjects: Grahamstown (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27651 , vital:69380
- Description: One of the recommendations made by the South African Law Commission (SALC) (1997) when discussing the issue of child justice was that the justice system should aim to promote the well-being of the child and deal with the child in an individualised way. This dissertation discusses recidivism in children after completing the Rhythm of Life (ROL) diversion programme which aims at diverting children who conflict with the law away from criminal procedures to programmes that assist in behaviour modification. The study is inspired by the need to uncover the effectiveness of the programme and the challenges encountered when it is delivered. It is further motivated by the need to expose the reasons why children return to the criminal justice system after having attended the ROL diversion programme. Additionally, it seeks to gain perspectives of the probation officers’ and parents’ insights on the observed changes after the attendance of the programme. The study utilised a qualitative methodology with an interpretive and descriptive paradigm, which used in-depth interviews and focus groups as a method of data collection. The participants of the study were children who completed the ROL diversion programme, parents or guardians of children who completed the ROL diversion programme, and probation officers implementing the programme. The data was analysed and presented following the following four themes, i.e., factors contributing to recidivism by children after completion of the ROL diversion programme, diversion programme content, and completion of the diversion programme and the effectiveness of the ROL diversion programme. The literature consulted was broken up into; the historical development of diversion programmes and the inherent legislative framework, the magnitude and extent of recidivism of children after completion of the ROL diversion programme, and the factors which contribute to recidivism by children after completion of the ROL diversion programme. The reviewed literature further scrutinised the global, regional, and South African perspectives on managing young people, and lastly reviewed the benefits and challenges of diversion programmes in general. The study used the social learning theory as a theoretical framework to explain and discuss recidivism and the effectiveness of diversion programmes. This is a general approach to psychology and regards criminal behaviour as no different from any kind of behaviour as it is learned through the processes of observation, imitation and vicarious reinforcement and punishment. The findings of the study revealed that the impact of absent and or lack of father figures in the family influenced the children to get involved in criminal activities. The findings further indicated that probation officers face various challenges when facilitating the programme, such as substance abuse by children, lack of resources and functional aids, and the language as the facilitator guide is written in English. It was also discovered that parents from the sample used an authoritarian style of parenting, which exerts high expectations from children while providing little in the way of feedback and nurturance. Lastly, the findings indicated that the ROL diversion programme does modify the behaviour of children on completion. However, the main challenge is the environment the children return to after completion as it is assumed as a contributing factor to committing the crime. One of the recommendations is to strengthen parenting programmes and to introduce a programme for parents or guardians of children with serious behavioural challenges, another recommendation is the development of a risk assessment tool for young people, to assist probation officers in holistically dealing with children. Additionally, probation service practitioners should be provided by the government with the necessary resources to ensure that aftercare services are rendered effectively and efficiently. The researcher lastly recommends that probation officers conduct an intervention evaluation after the programme to identify children who could not understand the content of the programme so that additional methods of intervention could be employed such as casework. The study had the following conclusions; risk factors such as lack of parental support, substance abuse, peer pressure and bereavement were causes for re-offending in the children interviewed; the programme manual presents a challenge in terms of language, because the manual is written in English, and not all children can understand English; the issue of restorative justice was overlooked by probation officers when dealing with children when they re-offended. The study also concluded that the ROL diversion programme is effective to a certain extent, depending on how the children utilize the skills acquired from the programme, and as the parents reflected that they observed a change in their children’s behaviour post-diversion, while children also expressed that they learnt valuable life skills which made them resilient. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
- Authors: Zimba, Thanduxolo
- Date: 2022-09
- Subjects: Grahamstown (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27651 , vital:69380
- Description: One of the recommendations made by the South African Law Commission (SALC) (1997) when discussing the issue of child justice was that the justice system should aim to promote the well-being of the child and deal with the child in an individualised way. This dissertation discusses recidivism in children after completing the Rhythm of Life (ROL) diversion programme which aims at diverting children who conflict with the law away from criminal procedures to programmes that assist in behaviour modification. The study is inspired by the need to uncover the effectiveness of the programme and the challenges encountered when it is delivered. It is further motivated by the need to expose the reasons why children return to the criminal justice system after having attended the ROL diversion programme. Additionally, it seeks to gain perspectives of the probation officers’ and parents’ insights on the observed changes after the attendance of the programme. The study utilised a qualitative methodology with an interpretive and descriptive paradigm, which used in-depth interviews and focus groups as a method of data collection. The participants of the study were children who completed the ROL diversion programme, parents or guardians of children who completed the ROL diversion programme, and probation officers implementing the programme. The data was analysed and presented following the following four themes, i.e., factors contributing to recidivism by children after completion of the ROL diversion programme, diversion programme content, and completion of the diversion programme and the effectiveness of the ROL diversion programme. The literature consulted was broken up into; the historical development of diversion programmes and the inherent legislative framework, the magnitude and extent of recidivism of children after completion of the ROL diversion programme, and the factors which contribute to recidivism by children after completion of the ROL diversion programme. The reviewed literature further scrutinised the global, regional, and South African perspectives on managing young people, and lastly reviewed the benefits and challenges of diversion programmes in general. The study used the social learning theory as a theoretical framework to explain and discuss recidivism and the effectiveness of diversion programmes. This is a general approach to psychology and regards criminal behaviour as no different from any kind of behaviour as it is learned through the processes of observation, imitation and vicarious reinforcement and punishment. The findings of the study revealed that the impact of absent and or lack of father figures in the family influenced the children to get involved in criminal activities. The findings further indicated that probation officers face various challenges when facilitating the programme, such as substance abuse by children, lack of resources and functional aids, and the language as the facilitator guide is written in English. It was also discovered that parents from the sample used an authoritarian style of parenting, which exerts high expectations from children while providing little in the way of feedback and nurturance. Lastly, the findings indicated that the ROL diversion programme does modify the behaviour of children on completion. However, the main challenge is the environment the children return to after completion as it is assumed as a contributing factor to committing the crime. One of the recommendations is to strengthen parenting programmes and to introduce a programme for parents or guardians of children with serious behavioural challenges, another recommendation is the development of a risk assessment tool for young people, to assist probation officers in holistically dealing with children. Additionally, probation service practitioners should be provided by the government with the necessary resources to ensure that aftercare services are rendered effectively and efficiently. The researcher lastly recommends that probation officers conduct an intervention evaluation after the programme to identify children who could not understand the content of the programme so that additional methods of intervention could be employed such as casework. The study had the following conclusions; risk factors such as lack of parental support, substance abuse, peer pressure and bereavement were causes for re-offending in the children interviewed; the programme manual presents a challenge in terms of language, because the manual is written in English, and not all children can understand English; the issue of restorative justice was overlooked by probation officers when dealing with children when they re-offended. The study also concluded that the ROL diversion programme is effective to a certain extent, depending on how the children utilize the skills acquired from the programme, and as the parents reflected that they observed a change in their children’s behaviour post-diversion, while children also expressed that they learnt valuable life skills which made them resilient. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
Sustainability challenges of community newspapers: The case study of iDike-Lethu Community Newspaper
- Authors: Ndarane, Luvuyo Gladstone
- Date: 2022-09
- Subjects: Community newspapers , Journalism, Regional
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23754 , vital:60485
- Description: Community newspapers are an important source of information and play a vital role in the development of communities. They are, therefore, an important stakeholder in community development. IDike-Lethu community newspaper`s presence in the community of Alice and in the areas where it is distributed is facilitating communication and development in these areas. Raymond Mhlaba Local Municipality is benefiting in the presence of iDike-Lethu because this newspaper is the conduit through which communication to its citizens is submitted. This study assessed the challenges iDike- Lethu is having that impact on its maximum contribution in this society. Participants in this study are residents of Alice and are readers of iDike-Lethu Community Newspaper. This study adopted a mixed method design in which questionnaires and interviews were used to collect primary data. Data collected was analyzed using both qualitative and quantitative methods. Major findings that impede smooth operations in this newspaper were discovered. These include inadequate funding, lack of technical backing and lack of community support. The study findings show that with all the challenges iDike-Lethu is having it continues to play a meaningful role by disseminating information, promoting local culture, equipping communities with skills and providing a platform on which these communities including local businesses send information across. Recommendations include the need for this newspaper to find a commercial, profitable and sustainable financial model which will support and reinforce its operations. This study will contribute in further research of methods to link communities and community newspapers to work harmoniously. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
Sustainability challenges of community newspapers: The case study of iDike-Lethu Community Newspaper
- Authors: Ndarane, Luvuyo Gladstone
- Date: 2022-09
- Subjects: Community newspapers , Journalism, Regional
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23754 , vital:60485
- Description: Community newspapers are an important source of information and play a vital role in the development of communities. They are, therefore, an important stakeholder in community development. IDike-Lethu community newspaper`s presence in the community of Alice and in the areas where it is distributed is facilitating communication and development in these areas. Raymond Mhlaba Local Municipality is benefiting in the presence of iDike-Lethu because this newspaper is the conduit through which communication to its citizens is submitted. This study assessed the challenges iDike- Lethu is having that impact on its maximum contribution in this society. Participants in this study are residents of Alice and are readers of iDike-Lethu Community Newspaper. This study adopted a mixed method design in which questionnaires and interviews were used to collect primary data. Data collected was analyzed using both qualitative and quantitative methods. Major findings that impede smooth operations in this newspaper were discovered. These include inadequate funding, lack of technical backing and lack of community support. The study findings show that with all the challenges iDike-Lethu is having it continues to play a meaningful role by disseminating information, promoting local culture, equipping communities with skills and providing a platform on which these communities including local businesses send information across. Recommendations include the need for this newspaper to find a commercial, profitable and sustainable financial model which will support and reinforce its operations. This study will contribute in further research of methods to link communities and community newspapers to work harmoniously. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2022
- Full Text:
- Date Issued: 2022-09
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