In silico analysis of the effects of non-synonymous single nucleotide polymorphisms on the human macrophage migration inhibitory factor gene and their possible role in human African trypanosomiasis susceptibility
- Authors: Kimuda, Magambo Philip
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3047 , vital:20355
- Description: Human African trypanosomiasis (HAT) is a public health problem in sub-Saharan Africa, with approximately 10,000 cases being reported per year. The Macrophage Migration Inhibitory Factor (MIF) which is encoded by a functionally polymorphic gene is important in both innate andadaptive immune responses, and has been implicated in affecting the outcome and processes of several inflammatory conditions. A recent study in mice to that effect showed that MIF deficient and anti-MIF antibody treated mice showed lowered inflammatory responses, liver damage and anaemia than the wild type mice when experimentally challenged with Trypanosomes. These findings could mean that the transcript levels and/or polymorphisms in this gene can possibly affect individual risk to trypanosomiasis. This is especially of interest because there have been reports of spontaneous recovery i.e self-cure/resistance in some HAT cases in West Africa. Prior to this discovery the general paradigm was that trypanosomiasis is fatal if left untreated. The aim of this study was to gain insights into how human genetic variation in forms of nonsynonymous SNPs affects the MIF structure and function and possibly HAT susceptibility. NsSNPs in the mif gene were obtained from dbSNP. Through homology modeling, SNP prediction tools, protein interface analysis, alanine scanning, changes in free energy of folding, protein interactions calculator (PIC), and molecular dynamics simulations, SNP effects on the protein structure and function were studied. The study cohort comprised of human genome sequence data from 50 North Western Uganda Lugbara endemic individuals of whom 20 were cases (previous HAT patients) and 30 were controls (HAT free individuals). None of the 26 nsSNPs retrieved from dbSNP (July 2015) were present in the mif gene region in the study cohort. Out of the eight variants called in the mif coding region there was only one missense variant rs36065127 whose clinical significance is unknown. It was not possible to test for association of this variant with HAT due to its low global MAF that was less than 0.05. Alanine scanning provided a fast and computationally cheap means of quickly assessing nsSNPs of importance. NsSNPs that were interface residues were more likely to be hotspots (important in protein stability). Assessment of possible compensatory mutations using PIC analysis showed that some nsSNP sites were interacting with others, but this requires further experimentation. Analysis of changes in free energy using FOLDX was not enough to predict which nsSNPs would adversely affect protein structure, function and kinetics. The MD simulations were unfortunately too short to glean any meaningful inferences. This was the first genetic study carried out on the people of Lugbara ethnicity from North Western Uganda.
- Full Text:
- Date Issued: 2016
- Authors: Kimuda, Magambo Philip
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3047 , vital:20355
- Description: Human African trypanosomiasis (HAT) is a public health problem in sub-Saharan Africa, with approximately 10,000 cases being reported per year. The Macrophage Migration Inhibitory Factor (MIF) which is encoded by a functionally polymorphic gene is important in both innate andadaptive immune responses, and has been implicated in affecting the outcome and processes of several inflammatory conditions. A recent study in mice to that effect showed that MIF deficient and anti-MIF antibody treated mice showed lowered inflammatory responses, liver damage and anaemia than the wild type mice when experimentally challenged with Trypanosomes. These findings could mean that the transcript levels and/or polymorphisms in this gene can possibly affect individual risk to trypanosomiasis. This is especially of interest because there have been reports of spontaneous recovery i.e self-cure/resistance in some HAT cases in West Africa. Prior to this discovery the general paradigm was that trypanosomiasis is fatal if left untreated. The aim of this study was to gain insights into how human genetic variation in forms of nonsynonymous SNPs affects the MIF structure and function and possibly HAT susceptibility. NsSNPs in the mif gene were obtained from dbSNP. Through homology modeling, SNP prediction tools, protein interface analysis, alanine scanning, changes in free energy of folding, protein interactions calculator (PIC), and molecular dynamics simulations, SNP effects on the protein structure and function were studied. The study cohort comprised of human genome sequence data from 50 North Western Uganda Lugbara endemic individuals of whom 20 were cases (previous HAT patients) and 30 were controls (HAT free individuals). None of the 26 nsSNPs retrieved from dbSNP (July 2015) were present in the mif gene region in the study cohort. Out of the eight variants called in the mif coding region there was only one missense variant rs36065127 whose clinical significance is unknown. It was not possible to test for association of this variant with HAT due to its low global MAF that was less than 0.05. Alanine scanning provided a fast and computationally cheap means of quickly assessing nsSNPs of importance. NsSNPs that were interface residues were more likely to be hotspots (important in protein stability). Assessment of possible compensatory mutations using PIC analysis showed that some nsSNP sites were interacting with others, but this requires further experimentation. Analysis of changes in free energy using FOLDX was not enough to predict which nsSNPs would adversely affect protein structure, function and kinetics. The MD simulations were unfortunately too short to glean any meaningful inferences. This was the first genetic study carried out on the people of Lugbara ethnicity from North Western Uganda.
- Full Text:
- Date Issued: 2016
In vitro evaluation of antimicrobial and antioxidant activities of olea europaea subsp. africana and euryops brevipapposus used by Cala community folkloric medicine for the management of infections associated with chronic non-communicable diseases
- Authors: Adegborioye, Abiodun
- Date: 2016
- Subjects: Antioxidants , Medicinal plants , Traditional medicine -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/4869 , vital:28624
- Description: Chronic non-communicable diseses are a global public health challenge that continuously threatens the development and health of humans. Risk factors such as unbalanced diet-the high consumption of processed food or food from animal origin are responsible for NCDs. NCDs result in weakened immune system, making the host susceptible to opportunistic infections. Thus, the NCDs burden is most times chronic and multiple with the illness and suffering of the affected person numerous. The lack of cure for NCDs, the high cost of drugs, their high side-effects, and the emergence of multiple drug resistance has given rise to the investigation of other sources for therapeutic cure such as medicinal plants. The ethanol, n-hexane and ethyl acetate extracts of Olea europaea were analysed for their antioxidant and antimicrobial activities. The essential oil was also analysed for their chemical constituents. The n-hexane extracts of O. europaea exhibited no inhibition against all of the microorganisms tested, while the ethyl acetate and ethanol extracts exhibited inhibition, with minimum inhibitory concentration values between 0.625 mg/ml to 1.25 mg/ml. The ethanol leaf and ethyl acetate stem extracts exhibited significant activity in the inhibition of 2, 2-azinobis-(3-ethylbenzothiazolin - 6-sulfonic acid diammonium salt (ABTS) free radical, the n-hexane leaf extract had the overall significant lipid peroxidation inhibition activity, while in the inhibition of 2, 2- diphenyl-1-picrylhydrazyl radical (DPPH), the ethanol and ethyl acetate leaf extracts had strong activity. Nonanal, phytol, α-Pinene, α-Phellandrene, spatulenol and farnesol were some of chemical components identified after the GC-MS analysis of O. europaea oil. In the final part of the dissertation, Euryops brevipapposus essential oil was assessed for the antioxidant activities using free radical scavenging assays. In addition to this, the antimicrobial activities were assessed and the chemical composition was analysed using GC-MS. The essential oil demonstrated significant antioxidant activity against 2, 2-diphenyl-2-picryl-hydrazyl free radical (DPPH), 2, 2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and lipid peroxides with IC50 value of 0.0000000671 mg/ml, 1.05 mg/ml, and 1.170 mg/ml respectively. The essential oil also showed significant activity against all microorganisms tested with minimum inhibitory concentration (MIC) values between 0.055 mg/ml to 0.5 mg/ml. α-pinene, α- Phellandrene, germacrene D, β-pinene, trans- β.-Ocimene, bicyclogermacrene and β -Phellandrene were some of the chemical compounds identified in E. brevipapposus oil. The study has shown that E. brevipapposus and O. europaea are abundant in phytochemical compounds which were thought to be the root cause for the activities demonstrated. Therefore, these therapeutic properties observed validate and elucidate the traditional usage of the both plants in the treatment /management of diseases.
- Full Text:
- Date Issued: 2016
- Authors: Adegborioye, Abiodun
- Date: 2016
- Subjects: Antioxidants , Medicinal plants , Traditional medicine -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/4869 , vital:28624
- Description: Chronic non-communicable diseses are a global public health challenge that continuously threatens the development and health of humans. Risk factors such as unbalanced diet-the high consumption of processed food or food from animal origin are responsible for NCDs. NCDs result in weakened immune system, making the host susceptible to opportunistic infections. Thus, the NCDs burden is most times chronic and multiple with the illness and suffering of the affected person numerous. The lack of cure for NCDs, the high cost of drugs, their high side-effects, and the emergence of multiple drug resistance has given rise to the investigation of other sources for therapeutic cure such as medicinal plants. The ethanol, n-hexane and ethyl acetate extracts of Olea europaea were analysed for their antioxidant and antimicrobial activities. The essential oil was also analysed for their chemical constituents. The n-hexane extracts of O. europaea exhibited no inhibition against all of the microorganisms tested, while the ethyl acetate and ethanol extracts exhibited inhibition, with minimum inhibitory concentration values between 0.625 mg/ml to 1.25 mg/ml. The ethanol leaf and ethyl acetate stem extracts exhibited significant activity in the inhibition of 2, 2-azinobis-(3-ethylbenzothiazolin - 6-sulfonic acid diammonium salt (ABTS) free radical, the n-hexane leaf extract had the overall significant lipid peroxidation inhibition activity, while in the inhibition of 2, 2- diphenyl-1-picrylhydrazyl radical (DPPH), the ethanol and ethyl acetate leaf extracts had strong activity. Nonanal, phytol, α-Pinene, α-Phellandrene, spatulenol and farnesol were some of chemical components identified after the GC-MS analysis of O. europaea oil. In the final part of the dissertation, Euryops brevipapposus essential oil was assessed for the antioxidant activities using free radical scavenging assays. In addition to this, the antimicrobial activities were assessed and the chemical composition was analysed using GC-MS. The essential oil demonstrated significant antioxidant activity against 2, 2-diphenyl-2-picryl-hydrazyl free radical (DPPH), 2, 2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and lipid peroxides with IC50 value of 0.0000000671 mg/ml, 1.05 mg/ml, and 1.170 mg/ml respectively. The essential oil also showed significant activity against all microorganisms tested with minimum inhibitory concentration (MIC) values between 0.055 mg/ml to 0.5 mg/ml. α-pinene, α- Phellandrene, germacrene D, β-pinene, trans- β.-Ocimene, bicyclogermacrene and β -Phellandrene were some of the chemical compounds identified in E. brevipapposus oil. The study has shown that E. brevipapposus and O. europaea are abundant in phytochemical compounds which were thought to be the root cause for the activities demonstrated. Therefore, these therapeutic properties observed validate and elucidate the traditional usage of the both plants in the treatment /management of diseases.
- Full Text:
- Date Issued: 2016
Incidence and molecular characterization of Hepatitis E virus from swine herds in the Eastern Cape province, South Africa
- Authors: Adelabu, Olusesan Adeyemi
- Date: 2016
- Subjects: Hepatitis -- South Africa -- Eastern Cape Virology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13966 , vital:39734
- Description: Hepatitis E virus-mediated infection is a serious public health concern in economically developing nations of the world. Globally, four major genotypes of HEV have been documented and the swine HEV identified to date in different countries belongs to either genotype 3 or 4. It has been reported to cross species barrier and cause infections in humans. Hence, Hepatitis E has been suggested to be zoonotic owing to the increase of evidence through various studies. Thus far, genotypes 1 and 2 are exclusively found in human population. However, little data are available regarding the occurrence of HEV in South Africa, especially in the Eastern Cape Province. Hence, this study was designed to assess the prevalence of Hepatitis E Virus among swine herd in selected communal and commercial farms in the Eastern Cape Province of South Africa. A total of 160 faecal samples were collected from swine herds in Amathole and Chris Hani District Municipalities of Eastern Cape Province and screened for the presence of HEV. Faecal samples were collected, using sterile swabs, from swine between the age of 2 to 6 months old, placed on ice and transported to the laboratory for further analysis. Viral RNA extraction was carried out followed by nested reverse-transcriptase polymerase chain reaction was used for amplification, after which the amplified products were examined by electrophoresis and viewed under ultraviolet illumination. The positive PCR products were sent for sequencing. Of the 160 faecal samples screened, only seven were positive (4.4percent) for HEV. The nucleotide sequence analyses revealed isolates UFT 01-03 sharing 82percent to 99percent identities with other strains with accession numbers KX896664, KX896665 and KX896666 and UMCF 01-04 with KX896667, KX896668, KX896669 and KX896670 from different regions of the world Phylogenetic analysis also showed that all seven isolates from this study clustered with both human and swine HEV from different geographical regions of the world especially with Japan Human and swine strains, Netherland swine HEV strains (AY032758, AF332620) and human HEV strain from France (JQ763611). We conclude that HEV is present among swine in the Eastern Cape Province, albeit in low incidence, and this does have public health implications. There is need for maintenance of high hygienic standards in order to prevent human infections through swine faecal materials and appropriate cooking of pork is highly advised.
- Full Text:
- Date Issued: 2016
- Authors: Adelabu, Olusesan Adeyemi
- Date: 2016
- Subjects: Hepatitis -- South Africa -- Eastern Cape Virology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13966 , vital:39734
- Description: Hepatitis E virus-mediated infection is a serious public health concern in economically developing nations of the world. Globally, four major genotypes of HEV have been documented and the swine HEV identified to date in different countries belongs to either genotype 3 or 4. It has been reported to cross species barrier and cause infections in humans. Hence, Hepatitis E has been suggested to be zoonotic owing to the increase of evidence through various studies. Thus far, genotypes 1 and 2 are exclusively found in human population. However, little data are available regarding the occurrence of HEV in South Africa, especially in the Eastern Cape Province. Hence, this study was designed to assess the prevalence of Hepatitis E Virus among swine herd in selected communal and commercial farms in the Eastern Cape Province of South Africa. A total of 160 faecal samples were collected from swine herds in Amathole and Chris Hani District Municipalities of Eastern Cape Province and screened for the presence of HEV. Faecal samples were collected, using sterile swabs, from swine between the age of 2 to 6 months old, placed on ice and transported to the laboratory for further analysis. Viral RNA extraction was carried out followed by nested reverse-transcriptase polymerase chain reaction was used for amplification, after which the amplified products were examined by electrophoresis and viewed under ultraviolet illumination. The positive PCR products were sent for sequencing. Of the 160 faecal samples screened, only seven were positive (4.4percent) for HEV. The nucleotide sequence analyses revealed isolates UFT 01-03 sharing 82percent to 99percent identities with other strains with accession numbers KX896664, KX896665 and KX896666 and UMCF 01-04 with KX896667, KX896668, KX896669 and KX896670 from different regions of the world Phylogenetic analysis also showed that all seven isolates from this study clustered with both human and swine HEV from different geographical regions of the world especially with Japan Human and swine strains, Netherland swine HEV strains (AY032758, AF332620) and human HEV strain from France (JQ763611). We conclude that HEV is present among swine in the Eastern Cape Province, albeit in low incidence, and this does have public health implications. There is need for maintenance of high hygienic standards in order to prevent human infections through swine faecal materials and appropriate cooking of pork is highly advised.
- Full Text:
- Date Issued: 2016
Incorporation of environmental issues in South Africa’s municipal Integrated Development Plans
- Ruwanza, Sheunesu, Shackleton, Charlie M
- Authors: Ruwanza, Sheunesu , Shackleton, Charlie M
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/180481 , vital:43393 , xlink:href="https://doi.org/10.1080/13504509.2015.1062161"
- Description: The transition to full democracy in South Africa in 1994 saw local government becoming the focal point for dealing with socio-economic development needs of communities. The Integrated Development Plan (IDP) has been used as the tool for guiding local development objectives, balanced against environmental demands within a sustainable development paradigm. Here we examine the extent to which this is being achieved through an analysis of IDPs from 35 different municipalities at three scales. We test the hypothesis that the metropolitan municipalities are better at mainstreaming environmental issues into their IDPs than local and district municipalities. Results indicate that mainstreaming environmental issues in IDPs is still low. The hypothesis that metropoles are better at mainstreaming environmental issues than district and local municipalities was not accepted since there were no significant differences between municipalities. There was low relative budget allocations and inclusion of vision and mission statements that mainstream environmental issues in all municipalities. For mainstreaming of environmental issues to be effective in IDPs, both proactive approaches and multi-faceted bottom-up and top-down approaches are suggested.
- Full Text:
- Date Issued: 2016
- Authors: Ruwanza, Sheunesu , Shackleton, Charlie M
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/180481 , vital:43393 , xlink:href="https://doi.org/10.1080/13504509.2015.1062161"
- Description: The transition to full democracy in South Africa in 1994 saw local government becoming the focal point for dealing with socio-economic development needs of communities. The Integrated Development Plan (IDP) has been used as the tool for guiding local development objectives, balanced against environmental demands within a sustainable development paradigm. Here we examine the extent to which this is being achieved through an analysis of IDPs from 35 different municipalities at three scales. We test the hypothesis that the metropolitan municipalities are better at mainstreaming environmental issues into their IDPs than local and district municipalities. Results indicate that mainstreaming environmental issues in IDPs is still low. The hypothesis that metropoles are better at mainstreaming environmental issues than district and local municipalities was not accepted since there were no significant differences between municipalities. There was low relative budget allocations and inclusion of vision and mission statements that mainstream environmental issues in all municipalities. For mainstreaming of environmental issues to be effective in IDPs, both proactive approaches and multi-faceted bottom-up and top-down approaches are suggested.
- Full Text:
- Date Issued: 2016
Indigenous forests level of deforestation, forest dependency and factors determining willingness to participate in indigenous forest conservation: evidence from resettled farmers of Shamva, Zimbabwe
- Authors: Chivheya, Renias V
- Date: 2016
- Subjects: Forest conservation -- Zimbabwe Forests and forestry -- Economic aspects -- Zimbabwe Deforestation -- Zimbabwe
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/2370 , vital:27786
- Description: This study first explored the rate of forest deforestation in Shamva resettlement areas. It then identified and estimated the extent to which these resettled farmers depend on forest for their livelihoods. Evaluation of farmer perceptions on management issues and willingness to participate in indigenous forest conservation and the socio-economic and institutional factors which affect their willingness to participate were also done. Finally the study sought to identify incentives for forests conservation. The study was conducted in Shamva district in Mashonaland Central province. And the respondents were stratified into three groups: A1, A2 and Old resettlement models. The three models differ on how they were implemented and supported which might render them to have different deforestation rates, livelihood strategies and forest dependency. A total of 247 respondents were surveyed, consisting of 98 A1 farmers, 50 A2 farmers and 99 Old resettled farmers. The data was collected using GIS and remote sensing, structured questionnaire interviews and direct observation. The data was analysed using descriptive analysis, KAP analytic framework and binary logistic regression analysis. The land cover/changes results revealed that both deforestation and afforestation are taking place in Shamva resettlement. Woodland and bushland were decreasing, croplands were also decreasing. However woodland dense and grasslands were increasing. Deforestation was found to be as a result of the resettled farmers’ livelihood strategies which were found to be diverse and agriculture being dominant in all models. All the farmers depended on the forest but at varying levels of 19 percent for Old and 14 percent forA1 and 0.02 percent for A2 resettle farmers. 84 percent of the interviewed farmers however, indicated that they are willing to conserve forest with A1 farmers being the highest followed by A2 86 percent and lastly Old resettled farmers at 76.8 percent. Results of the binary regression model revealed that the significant factors which explain willingness to participate in indigenous forest conservation are age, marital status, education, gender, institution, culture and belief, employment and household size. The highest preferred incentive was the provision of free seedlings and the lowest was out grower scheme. The study recommends that GIS and remote sensing should be used to monitor deforestation, off farm projects be encouraged, exotic and indigenous trees be promoted and forest conservation education be promoted in resettlement areas.
- Full Text:
- Date Issued: 2016
- Authors: Chivheya, Renias V
- Date: 2016
- Subjects: Forest conservation -- Zimbabwe Forests and forestry -- Economic aspects -- Zimbabwe Deforestation -- Zimbabwe
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/2370 , vital:27786
- Description: This study first explored the rate of forest deforestation in Shamva resettlement areas. It then identified and estimated the extent to which these resettled farmers depend on forest for their livelihoods. Evaluation of farmer perceptions on management issues and willingness to participate in indigenous forest conservation and the socio-economic and institutional factors which affect their willingness to participate were also done. Finally the study sought to identify incentives for forests conservation. The study was conducted in Shamva district in Mashonaland Central province. And the respondents were stratified into three groups: A1, A2 and Old resettlement models. The three models differ on how they were implemented and supported which might render them to have different deforestation rates, livelihood strategies and forest dependency. A total of 247 respondents were surveyed, consisting of 98 A1 farmers, 50 A2 farmers and 99 Old resettled farmers. The data was collected using GIS and remote sensing, structured questionnaire interviews and direct observation. The data was analysed using descriptive analysis, KAP analytic framework and binary logistic regression analysis. The land cover/changes results revealed that both deforestation and afforestation are taking place in Shamva resettlement. Woodland and bushland were decreasing, croplands were also decreasing. However woodland dense and grasslands were increasing. Deforestation was found to be as a result of the resettled farmers’ livelihood strategies which were found to be diverse and agriculture being dominant in all models. All the farmers depended on the forest but at varying levels of 19 percent for Old and 14 percent forA1 and 0.02 percent for A2 resettle farmers. 84 percent of the interviewed farmers however, indicated that they are willing to conserve forest with A1 farmers being the highest followed by A2 86 percent and lastly Old resettled farmers at 76.8 percent. Results of the binary regression model revealed that the significant factors which explain willingness to participate in indigenous forest conservation are age, marital status, education, gender, institution, culture and belief, employment and household size. The highest preferred incentive was the provision of free seedlings and the lowest was out grower scheme. The study recommends that GIS and remote sensing should be used to monitor deforestation, off farm projects be encouraged, exotic and indigenous trees be promoted and forest conservation education be promoted in resettlement areas.
- Full Text:
- Date Issued: 2016
Individualism, collectivism and gender as correlates of the work ethic among the employees in a government department in the Eastern Cape
- Authors: Gwelo, Blessing
- Date: 2016
- Subjects: Individualism Collectivism Work ethic
- Language: English
- Type: Thesis , Masters , Industrial Psychology
- Identifier: http://hdl.handle.net/10353/11608 , vital:39089
- Description: This study investigated the relationship between individualism, collectivism and gender among the employees at the Department of Justice and Constitutional Development situated in East London, South Africa. Individualism, collectivism and gender were used as independent variables in the study while the work ethic was used as the dependent variable. Data was gathered from a random sample of 260 employees in the Department. A questionnaire consisting of three parts was used for data collection. To gather biographical and occupational data, a self-designed 5-item questionnaire was used. The 65 item Multidimensional Work Ethic Profile (MWEP) scale Miller et al. (2002) was used to measure the work ethic. A 16-item individualism/collectivism scale (also known as the Culture Orientation Scale) formulated by Triandis & Gelfand (1998) was used in the research to measure individualism/collectivism. Data analysis was done by means of various statistical techniques, including the Pearson Product Moment Correlation Technique and Multiple Regression Analysis. The results indicated that there is a significant positive correlation between individualism and the work ethic, noting that a positive correlation for individualism implies a negative correlation for collectivism. The results of this study also found males showing to have higher work ethic than females. The results indicated that individualism/collectivism and gender together do not account for a higher proportion of variance in work ethic than any of the two separately. The study, therefore, recommends that managers must do all in their power to promote the growth and development of work ethic in their organisations through encouraging individualism, and through striving to increase the work ethic in females.
- Full Text:
- Date Issued: 2016
- Authors: Gwelo, Blessing
- Date: 2016
- Subjects: Individualism Collectivism Work ethic
- Language: English
- Type: Thesis , Masters , Industrial Psychology
- Identifier: http://hdl.handle.net/10353/11608 , vital:39089
- Description: This study investigated the relationship between individualism, collectivism and gender among the employees at the Department of Justice and Constitutional Development situated in East London, South Africa. Individualism, collectivism and gender were used as independent variables in the study while the work ethic was used as the dependent variable. Data was gathered from a random sample of 260 employees in the Department. A questionnaire consisting of three parts was used for data collection. To gather biographical and occupational data, a self-designed 5-item questionnaire was used. The 65 item Multidimensional Work Ethic Profile (MWEP) scale Miller et al. (2002) was used to measure the work ethic. A 16-item individualism/collectivism scale (also known as the Culture Orientation Scale) formulated by Triandis & Gelfand (1998) was used in the research to measure individualism/collectivism. Data analysis was done by means of various statistical techniques, including the Pearson Product Moment Correlation Technique and Multiple Regression Analysis. The results indicated that there is a significant positive correlation between individualism and the work ethic, noting that a positive correlation for individualism implies a negative correlation for collectivism. The results of this study also found males showing to have higher work ethic than females. The results indicated that individualism/collectivism and gender together do not account for a higher proportion of variance in work ethic than any of the two separately. The study, therefore, recommends that managers must do all in their power to promote the growth and development of work ethic in their organisations through encouraging individualism, and through striving to increase the work ethic in females.
- Full Text:
- Date Issued: 2016
Indolyl-3-ethanone-α-thioethers: a promising new class of non-toxic antimalarial agents
- Svogie, Archibald L, Isaacs, Michelle, Hoppe, Heinrich C, Khanye, Setshaba D, Veale, Clinton G L
- Authors: Svogie, Archibald L , Isaacs, Michelle , Hoppe, Heinrich C , Khanye, Setshaba D , Veale, Clinton G L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66233 , vital:28920 , https://doi.org/10.1016/j.ejmech.2016.02.056
- Description: publisher version , The success of chemotherapeutics in easing the burden of malaria is under continuous threat from ever-evolving parasite resistance, including resistance to artemisinin combination therapies. Therefore, the discovery of new classes of antimalarials which inhibit new biological targets is imperative to controlling malaria. Accordingly, we report here the discovery of indolyl-3-ethanone-α-thioethers, a new class of antimalarial compounds with encouraging activity. Synthesis of a focused library of compounds revealed important insight into the SAR of this class of compounds, including critical information regarding the position and chemical nature of substituents on both the thiophenol and indole rings. This investigation ultimately led to the discovery of two hit compounds (16 and 27) which exhibited nano molar in vitro antimalarial activity coupled to no observable toxicity against a HeLa cell line.
- Full Text: false
- Date Issued: 2016
- Authors: Svogie, Archibald L , Isaacs, Michelle , Hoppe, Heinrich C , Khanye, Setshaba D , Veale, Clinton G L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66233 , vital:28920 , https://doi.org/10.1016/j.ejmech.2016.02.056
- Description: publisher version , The success of chemotherapeutics in easing the burden of malaria is under continuous threat from ever-evolving parasite resistance, including resistance to artemisinin combination therapies. Therefore, the discovery of new classes of antimalarials which inhibit new biological targets is imperative to controlling malaria. Accordingly, we report here the discovery of indolyl-3-ethanone-α-thioethers, a new class of antimalarial compounds with encouraging activity. Synthesis of a focused library of compounds revealed important insight into the SAR of this class of compounds, including critical information regarding the position and chemical nature of substituents on both the thiophenol and indole rings. This investigation ultimately led to the discovery of two hit compounds (16 and 27) which exhibited nano molar in vitro antimalarial activity coupled to no observable toxicity against a HeLa cell line.
- Full Text: false
- Date Issued: 2016
Industrial policy, institutions and industrial financing in South Africa: the role of the IDC and DBSA, and lessons from Brazil’s BNDES
- Authors: Fumbata, Nandipha
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1132 , http://hdl.handle.net/10962/d1021278
- Description: Institutions, particularly development finance institutions (DFIs) have been instrumental in economic development and the implementation of industrial policy throughout history. In 2007, the South African government identified the country’s DFIs as key to the implementation of its new industrial policy framework with the main objective of job creation. This thesis examines the impact that South Africa’s DFIs, particularly the IDC and the DBSA, have had on employment creation from 2010 to 2014. A comparative institutional approach is adopted in a case study analysis examining the role of the state in industrial financing. The financing activities of Brazil’s BNDES are explored by comparison to determine if there are possible lessons for South Africa. An analysis of the DFIs’ financial and annual reports and government policy documents is conducted. The political settlements framework is used as a basis for understanding the balance of power within the country and the impact this has had on the country’s industrial policy and industrial finance. The thesis finds that the financing activities of South Africa’s DFIs, particularly the IDC, have been directed at large scale capital intensive projects, with a large portion of disbursements channelled towards mining and mineral beneficiation. These sectors have also facilitated the most number of jobs. Even though the activities of the country’s DFIs are consistent with South Africa’s industrial policy and have facilitated job creation, it is evident that these efforts have not been on a scale that is large enough to reduce unemployment. Despite the DFIs’ efforts, there has been an increase in the number of unemployed South Africans between 2010 and 2014.
- Full Text:
- Date Issued: 2016
- Authors: Fumbata, Nandipha
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1132 , http://hdl.handle.net/10962/d1021278
- Description: Institutions, particularly development finance institutions (DFIs) have been instrumental in economic development and the implementation of industrial policy throughout history. In 2007, the South African government identified the country’s DFIs as key to the implementation of its new industrial policy framework with the main objective of job creation. This thesis examines the impact that South Africa’s DFIs, particularly the IDC and the DBSA, have had on employment creation from 2010 to 2014. A comparative institutional approach is adopted in a case study analysis examining the role of the state in industrial financing. The financing activities of Brazil’s BNDES are explored by comparison to determine if there are possible lessons for South Africa. An analysis of the DFIs’ financial and annual reports and government policy documents is conducted. The political settlements framework is used as a basis for understanding the balance of power within the country and the impact this has had on the country’s industrial policy and industrial finance. The thesis finds that the financing activities of South Africa’s DFIs, particularly the IDC, have been directed at large scale capital intensive projects, with a large portion of disbursements channelled towards mining and mineral beneficiation. These sectors have also facilitated the most number of jobs. Even though the activities of the country’s DFIs are consistent with South Africa’s industrial policy and have facilitated job creation, it is evident that these efforts have not been on a scale that is large enough to reduce unemployment. Despite the DFIs’ efforts, there has been an increase in the number of unemployed South Africans between 2010 and 2014.
- Full Text:
- Date Issued: 2016
Inequality in South Africa: a possible solution within the labour market
- Authors: Ferreira, John-Edward
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4047 , vital:20594
- Description: This study sets out to identify the most effective way in which persistently and unacceptably high levels of inequality can be reduced in South Africa. Three alternative approaches were identified from the literature and their impact explored statistically. They are: the introduction of a ‘Social Solidarity Grant’; a decrease in unemployment by 5%; and a narrowing of the skill premium through an expansion of tertiary education. It is important to note that the study makes no attempt at explaining how these outcomes might be implemented or achieved. Rather, it sets out to determine only the effect that such policies may have on measured inequality. It was found that while the introduction of a new grant had a significant effect on inequality, this effect however, was once-off. The grant would be financed by individuals in the top decile through tax increases, which would be a complicated endeavour. Both job creation and a narrowing of the skills premium were significantly effective in decreasing inequality. The narrowing of the skills premium showed more promise due to its accelerating effectiveness in decreasing inequality over time and the fact that it directly addresses the problem of wage differentials. It was noted that the extreme levels of poverty and unemployment in South Africa may dampen enthusiasm for policies that narrow the skills premium to reduce inequality. These characteristics make job creation a more popular policy option because of the positive impact on poverty and unemployment as well as on inequality.
- Full Text:
- Date Issued: 2016
- Authors: Ferreira, John-Edward
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4047 , vital:20594
- Description: This study sets out to identify the most effective way in which persistently and unacceptably high levels of inequality can be reduced in South Africa. Three alternative approaches were identified from the literature and their impact explored statistically. They are: the introduction of a ‘Social Solidarity Grant’; a decrease in unemployment by 5%; and a narrowing of the skill premium through an expansion of tertiary education. It is important to note that the study makes no attempt at explaining how these outcomes might be implemented or achieved. Rather, it sets out to determine only the effect that such policies may have on measured inequality. It was found that while the introduction of a new grant had a significant effect on inequality, this effect however, was once-off. The grant would be financed by individuals in the top decile through tax increases, which would be a complicated endeavour. Both job creation and a narrowing of the skills premium were significantly effective in decreasing inequality. The narrowing of the skills premium showed more promise due to its accelerating effectiveness in decreasing inequality over time and the fact that it directly addresses the problem of wage differentials. It was noted that the extreme levels of poverty and unemployment in South Africa may dampen enthusiasm for policies that narrow the skills premium to reduce inequality. These characteristics make job creation a more popular policy option because of the positive impact on poverty and unemployment as well as on inequality.
- Full Text:
- Date Issued: 2016
Infecting the city: site-situational performance and ambulatory hermeneutics
- Authors: Simbao, Ruth K
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146156 , vital:38500 , DOI: 10.1080/09528822.2016.1266776
- Description: This article proposes the term ‘site-situational’ art or performance as a meaningful shift beyond ‘site-specificity’ and as a way to develop forward-moving and relational understandings of place. While place falls prey to Western, modernist stereotypes of closed, territorial geographic systems, site-situational readings, radical forms of ‘recognition’ and ambulatory hermeneutics enable an understanding of place as a wandering signifier, a trickster figure, and an in-the-moment conversation between environments and living beings. Through an analysis of the 2009 Infecting the City performing arts festival in South Africa, the article links site-situational performance to situational understandings of identification in the context of migration and xenophobia. It connects the participatory creative resistance aspired to by the Situationists that transforms situations rather than just recognises them, to the potential mutuality that can be experienced when one recognises oneself in the face of a ‘foreigner’ as well as the potential culpability that accompanies pro-active recognition-on-the-run.
- Full Text:
- Date Issued: 2016
- Authors: Simbao, Ruth K
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146156 , vital:38500 , DOI: 10.1080/09528822.2016.1266776
- Description: This article proposes the term ‘site-situational’ art or performance as a meaningful shift beyond ‘site-specificity’ and as a way to develop forward-moving and relational understandings of place. While place falls prey to Western, modernist stereotypes of closed, territorial geographic systems, site-situational readings, radical forms of ‘recognition’ and ambulatory hermeneutics enable an understanding of place as a wandering signifier, a trickster figure, and an in-the-moment conversation between environments and living beings. Through an analysis of the 2009 Infecting the City performing arts festival in South Africa, the article links site-situational performance to situational understandings of identification in the context of migration and xenophobia. It connects the participatory creative resistance aspired to by the Situationists that transforms situations rather than just recognises them, to the potential mutuality that can be experienced when one recognises oneself in the face of a ‘foreigner’ as well as the potential culpability that accompanies pro-active recognition-on-the-run.
- Full Text:
- Date Issued: 2016
Influence of argon-implantation on conventional and phototransferred thermoluminescence of synthetic quartz
- Nsengiyumva, S, Chithambo, Makaiko L, Pichon, L
- Authors: Nsengiyumva, S , Chithambo, Makaiko L , Pichon, L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124732 , vital:35656 , DOI: 10.1080/10420150.2016.1194412
- Description: Conventional and phototransferred thermoluminescence of crystalline synthetic quartz implanted with 70 keV Ar ions at fluences in the range 1 × 1014–5 × 1015 ions/cm2 is reported. The glow curves, recorded at 5°C/s from beta-irradiated samples of similar mass, show a prominent peak between 100°C and 120°C. The thermoluminescence intensity of all implanted samples was greater than that of the unimplanted one. The increase in sensitivity is attributed to a corresponding increase in the concentration of point defects, as a result of the implantation, which act as electron traps or recombination centres. Kinetic analysis carried out using the peak shape, whole glow-peak and curve-fitting methods produced values of the activation energy, frequency factor and order of kinetics that are generally independent of implantation fluence. This result suggests that implantation did not necessarily affect the nature of the electron traps. With respect to phototransferred thermoluminescence, it was observed that it only appeared in the sample implanted at the highest fluence of 5 × 1015 ions/cm2. This may be so because the concentration of deep traps produced as a result of implantation at low fluence is too low to give rise to phototransferred thermoluminescence. The intensity of the phototransferred thermoluminescence goes through a peak with illumination time. We attribute this behaviour to the relative concentration of holes at recombination centres and phototransferred electrons at shallow traps.
- Full Text: false
- Date Issued: 2016
- Authors: Nsengiyumva, S , Chithambo, Makaiko L , Pichon, L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124732 , vital:35656 , DOI: 10.1080/10420150.2016.1194412
- Description: Conventional and phototransferred thermoluminescence of crystalline synthetic quartz implanted with 70 keV Ar ions at fluences in the range 1 × 1014–5 × 1015 ions/cm2 is reported. The glow curves, recorded at 5°C/s from beta-irradiated samples of similar mass, show a prominent peak between 100°C and 120°C. The thermoluminescence intensity of all implanted samples was greater than that of the unimplanted one. The increase in sensitivity is attributed to a corresponding increase in the concentration of point defects, as a result of the implantation, which act as electron traps or recombination centres. Kinetic analysis carried out using the peak shape, whole glow-peak and curve-fitting methods produced values of the activation energy, frequency factor and order of kinetics that are generally independent of implantation fluence. This result suggests that implantation did not necessarily affect the nature of the electron traps. With respect to phototransferred thermoluminescence, it was observed that it only appeared in the sample implanted at the highest fluence of 5 × 1015 ions/cm2. This may be so because the concentration of deep traps produced as a result of implantation at low fluence is too low to give rise to phototransferred thermoluminescence. The intensity of the phototransferred thermoluminescence goes through a peak with illumination time. We attribute this behaviour to the relative concentration of holes at recombination centres and phototransferred electrons at shallow traps.
- Full Text: false
- Date Issued: 2016
Influence of increased processing speed on the microstructure evolution and mechanical property relationship in friction stir welding of AA5182-H111 (T500)
- Authors: Bernard, Dreyer
- Date: 2016
- Subjects: Friction stir welding , Aluminum alloys -- Welding
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/7322 , vital:21319
- Description: Friction stir welding of 5xxx series aluminium is generally carried out at low travel speeds, which limits the commercial applications of this process. This manuscript discusses the dynamic eformation characteristics of AA5182-H111 (T500), which allowed a travel speed of 1500 mm/min to be realised. This was achieved by using a spindle speed of 500 rev/min; the same as that required to make a weld of 200 mm/min. The thermal cycles, microstructural evolution due to tool / work-piece interaction, and the local microstructural and mechanical properties of the completed weld are discussed for a travel speed for 200 mm/min and 1500 mm/min. At a rate of 200 mm/min, heat generated due to contact between the shoulder and work-piece surface was transferred ahead of the tool, driving dynamic recrystallization which lowered the flow stress. Hereafter the material entered the stir zone where it was extruded around the pin during a process of continuous dynamic crystallization. At a travel speed of 1500 mm/min, the rate of heat conduction ahead of the tool was not rapid enough, and the material was deformed at low temperatures. A low weld pitch rotations per unit length travelled) was required to ensure that the material was sufficiently strained, to allow the formation of geometric necessary boundaries, which resulted in grain subdivision. The number of high angle grain boundaries was increased through subdivision, thus, increasing the nucleation sites for dynamically recrystallized necklace grains to form. In the absence of heat conduction from the shoulder, the high plastic strain ahead of the tool provided the energy required to drive dynamic recrystallization. Heat was generated from the high plastic strain and during recrystallization, where the stored plastic energy was adiabatically released. Once the material entered the stir zone, the high strain rates associated with the tool rotation which drove dynamic recrystallization that allowed the material to reach high levels of strain, resulted significant grain refinement. The weld zone of the 200 mm/min displayed weld a slight increase in yield strength, with respect to the parent material, due to grain refinement to 10 μm, while the yield strength of the 1500 mm/min weld was significantly increased due to grain refinement to 5 μm. The high weld speed did, however, generate high tensile residual stresses. This work is not only significant for the field of friction stir welding, but also in terms of material processing. The dynamic deformation characteristics associated with Al-5Mg-Mn, alloys which was observed ahead of the tool, is of high value in processes where plastic deformation is applied to improve the mechanical properties of these alloys.
- Full Text:
- Date Issued: 2016
- Authors: Bernard, Dreyer
- Date: 2016
- Subjects: Friction stir welding , Aluminum alloys -- Welding
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/7322 , vital:21319
- Description: Friction stir welding of 5xxx series aluminium is generally carried out at low travel speeds, which limits the commercial applications of this process. This manuscript discusses the dynamic eformation characteristics of AA5182-H111 (T500), which allowed a travel speed of 1500 mm/min to be realised. This was achieved by using a spindle speed of 500 rev/min; the same as that required to make a weld of 200 mm/min. The thermal cycles, microstructural evolution due to tool / work-piece interaction, and the local microstructural and mechanical properties of the completed weld are discussed for a travel speed for 200 mm/min and 1500 mm/min. At a rate of 200 mm/min, heat generated due to contact between the shoulder and work-piece surface was transferred ahead of the tool, driving dynamic recrystallization which lowered the flow stress. Hereafter the material entered the stir zone where it was extruded around the pin during a process of continuous dynamic crystallization. At a travel speed of 1500 mm/min, the rate of heat conduction ahead of the tool was not rapid enough, and the material was deformed at low temperatures. A low weld pitch rotations per unit length travelled) was required to ensure that the material was sufficiently strained, to allow the formation of geometric necessary boundaries, which resulted in grain subdivision. The number of high angle grain boundaries was increased through subdivision, thus, increasing the nucleation sites for dynamically recrystallized necklace grains to form. In the absence of heat conduction from the shoulder, the high plastic strain ahead of the tool provided the energy required to drive dynamic recrystallization. Heat was generated from the high plastic strain and during recrystallization, where the stored plastic energy was adiabatically released. Once the material entered the stir zone, the high strain rates associated with the tool rotation which drove dynamic recrystallization that allowed the material to reach high levels of strain, resulted significant grain refinement. The weld zone of the 200 mm/min displayed weld a slight increase in yield strength, with respect to the parent material, due to grain refinement to 10 μm, while the yield strength of the 1500 mm/min weld was significantly increased due to grain refinement to 5 μm. The high weld speed did, however, generate high tensile residual stresses. This work is not only significant for the field of friction stir welding, but also in terms of material processing. The dynamic deformation characteristics associated with Al-5Mg-Mn, alloys which was observed ahead of the tool, is of high value in processes where plastic deformation is applied to improve the mechanical properties of these alloys.
- Full Text:
- Date Issued: 2016
Influence of the macro-economic environment on the construction sector's contribution to the South African economy, 1984 to 2011
- Authors: Babalola, Adewumi Joseph
- Date: 2016
- Subjects: Construction industry -- Economic aspects Economic development Environmental economics
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/5618 , vital:20916
- Description: The construction sector serves as the engine of growth to the South Africa economy because of its catalytic role in the growth and development of the country. This study focuses mainly on the influence of the macro-economic environment on the contribution of the private sector to construction in the South Africa economy from 1984 to 2011. Government construction work is considered to be an injection into the economy; in this regard, state construction is regarded as public investment in the economy; and therefore, it is anti-cyclic (Keynes, 1936). The aim of this study has been to develop an econometric model for predicting the influence of the macroeconomic environment on the contribution of the private sector to the construction sector in the South Africa economy. The research design adopted in this study was an “ex-post facto” type, otherwise known as a causal-comparative design. The data were extracted from the published sources of the South African National Statistics, namely SARB, Stats SA and Quantec SA. The estimation technique used in this study was the ARDL model using quarterly data from 1984 to 2011. This is because in the construction sector, the influence of the independent variables is always felt over time – rather than all at once. The results of this study show that there is a long run causal relationship between inflation rate, interest rate, real exchange rate, GDP and gdp in the construction sector. The descriptive statistical analysis shows that there is a negative relationship between variables inflation rate and interest rate and the private sector spending in construction. However, economic growth as well as growth in the construction sector has a positive relationship with the private sector spending in construction. Likewise, the real exchange rate and labour productivity in construction have a negative relationship with the private sector’s spending in construction and they are statistically insignificant. The variance decomposition analysis show that the private sector spending in construction explains about 75 per cent of it variations, followed by inflation rate that explains 21 per cent on the average; while the remaining variations, comprising about 4 per cent, were shared among the other independent variables, such as GDP, GDP in construction, the interest rate and the real exchange rate. It was discovered that only the inflation rate does Granger-cause the private sector spending in construction. From the finding it can be concluded that inflation rate is a significant explanatory variable in explaining the variation in the dependent variable during period under review. Policy recommendations are as follows: firstly, the monetary authorities in South Africa should embark on sound policies that would bring about low prices of the construction materials. This would ensure growth and development in the construction sector; secondly, a stimulating development plan that would encourage private sector investment in properties and infrastructural development must be instituted; thirdly, an alternative policy to the present inflation targeting is recommended that would bring about low inflation, high growth, low unemployment and stable exchange rate; fourthly, the present policy on interest rate must be reviewed to allow for more participation in construction projects by the private sectors of the economy; fifthly, due to the fact that fluctuation in the crude oil prices in the international market is one of the major factors causing high inflation rate in South Africa, government must source local alternative products that would bring down prices of construction materials.
- Full Text:
- Date Issued: 2016
- Authors: Babalola, Adewumi Joseph
- Date: 2016
- Subjects: Construction industry -- Economic aspects Economic development Environmental economics
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/5618 , vital:20916
- Description: The construction sector serves as the engine of growth to the South Africa economy because of its catalytic role in the growth and development of the country. This study focuses mainly on the influence of the macro-economic environment on the contribution of the private sector to construction in the South Africa economy from 1984 to 2011. Government construction work is considered to be an injection into the economy; in this regard, state construction is regarded as public investment in the economy; and therefore, it is anti-cyclic (Keynes, 1936). The aim of this study has been to develop an econometric model for predicting the influence of the macroeconomic environment on the contribution of the private sector to the construction sector in the South Africa economy. The research design adopted in this study was an “ex-post facto” type, otherwise known as a causal-comparative design. The data were extracted from the published sources of the South African National Statistics, namely SARB, Stats SA and Quantec SA. The estimation technique used in this study was the ARDL model using quarterly data from 1984 to 2011. This is because in the construction sector, the influence of the independent variables is always felt over time – rather than all at once. The results of this study show that there is a long run causal relationship between inflation rate, interest rate, real exchange rate, GDP and gdp in the construction sector. The descriptive statistical analysis shows that there is a negative relationship between variables inflation rate and interest rate and the private sector spending in construction. However, economic growth as well as growth in the construction sector has a positive relationship with the private sector spending in construction. Likewise, the real exchange rate and labour productivity in construction have a negative relationship with the private sector’s spending in construction and they are statistically insignificant. The variance decomposition analysis show that the private sector spending in construction explains about 75 per cent of it variations, followed by inflation rate that explains 21 per cent on the average; while the remaining variations, comprising about 4 per cent, were shared among the other independent variables, such as GDP, GDP in construction, the interest rate and the real exchange rate. It was discovered that only the inflation rate does Granger-cause the private sector spending in construction. From the finding it can be concluded that inflation rate is a significant explanatory variable in explaining the variation in the dependent variable during period under review. Policy recommendations are as follows: firstly, the monetary authorities in South Africa should embark on sound policies that would bring about low prices of the construction materials. This would ensure growth and development in the construction sector; secondly, a stimulating development plan that would encourage private sector investment in properties and infrastructural development must be instituted; thirdly, an alternative policy to the present inflation targeting is recommended that would bring about low inflation, high growth, low unemployment and stable exchange rate; fourthly, the present policy on interest rate must be reviewed to allow for more participation in construction projects by the private sectors of the economy; fifthly, due to the fact that fluctuation in the crude oil prices in the international market is one of the major factors causing high inflation rate in South Africa, government must source local alternative products that would bring down prices of construction materials.
- Full Text:
- Date Issued: 2016
Influences on the struggle over content: considering two fine art studio practice curricula in developing/ed contexts
- Authors: Belluigi, Dina Z
- Date: 2016
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59809 , vital:27653 , http://dx.doi.org/10.1080/13562517.2016.1183617
- Description: This paper considers the influences of curricula content on the nuances of teaching and learning practices, and the ways in such influences are complicated by the contexts within which they are situated. Generated data from within the particularity of two fine art schools, one operating from the developed world in the global ‘north’ and another the developing world in the ‘south’, considers how they have negotiated the contemporary push from the professional community of practice, led by ‘western’ artmaking, towards the discourse-interest of contextualism in fine art practice education, compared to the focus on skills and mastery of more out-dated formalism. Particular emphasis is placed on the significance of such influences and pressures on the structures and cultures of teaching and learning.
- Full Text: false
- Date Issued: 2016
- Authors: Belluigi, Dina Z
- Date: 2016
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59809 , vital:27653 , http://dx.doi.org/10.1080/13562517.2016.1183617
- Description: This paper considers the influences of curricula content on the nuances of teaching and learning practices, and the ways in such influences are complicated by the contexts within which they are situated. Generated data from within the particularity of two fine art schools, one operating from the developed world in the global ‘north’ and another the developing world in the ‘south’, considers how they have negotiated the contemporary push from the professional community of practice, led by ‘western’ artmaking, towards the discourse-interest of contextualism in fine art practice education, compared to the focus on skills and mastery of more out-dated formalism. Particular emphasis is placed on the significance of such influences and pressures on the structures and cultures of teaching and learning.
- Full Text: false
- Date Issued: 2016
Information security assurance model for an examination paper preparation process in a higher education institution
- Authors: Mogale, Miemie
- Date: 2016
- Subjects: Computer security -- Management -- Examinations , Computers -- Access control
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/8509 , vital:26377
- Description: In today’s business world, information has become the driving force of organizations. With organizations transmitting large amounts of information to various geographical locations, it is imperative that organizations ensure the protection of their valuable commodity. Organizations should ensure that only authorized individuals receive, view and alter the information. This is also true to Higher Education Institutions (HEIs), which need to protect its examination papers, amongst other valuable information. With various threats waiting to take advantage of the examination papers, HEIs need to be prepared by equipping themselves with an information security management system (ISMS), in order to ensure that the process of setting examination papers is secure, and protects the examination papers within the process. An ISMS will ensure that all information security aspects are considered and addressed in order to provide appropriate and adequate protection for the examination papers. With the assistance of information security concepts and information security principles, the ISMS can be developed, in order to secure the process of preparing examination papers; in order to protect the examination papers from potential risks. Risk assessment form part of the ISMS, and is at the centre of any security effort; reason being that to secure an information environment, knowing and understanding the risks is imperative. Risks pertaining to that particular environment need to be assessed in order to deal with those appropriately. In addition, very important to any security effort is ensuring that employees working with the valuable information are made aware of these risks, and can be able to protect the information. Therefore, the role players (within the examination paper preparation process (EPPP)) who handle the examination papers on a daily basis have to be equipped with means of handling valuable information in a secure manner. Some of the role players’ behaviour and practices while handling the information could be seen as vulnerabilities that could be exploited by threats, resulting in the compromise in the CIA of the information. Therefore, it is imperative that role players are made aware of their practices and iv behaviour that could result in a negative impact for the institution. This awareness forms part and is addressed in the ISMS.
- Full Text:
- Date Issued: 2016
- Authors: Mogale, Miemie
- Date: 2016
- Subjects: Computer security -- Management -- Examinations , Computers -- Access control
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/8509 , vital:26377
- Description: In today’s business world, information has become the driving force of organizations. With organizations transmitting large amounts of information to various geographical locations, it is imperative that organizations ensure the protection of their valuable commodity. Organizations should ensure that only authorized individuals receive, view and alter the information. This is also true to Higher Education Institutions (HEIs), which need to protect its examination papers, amongst other valuable information. With various threats waiting to take advantage of the examination papers, HEIs need to be prepared by equipping themselves with an information security management system (ISMS), in order to ensure that the process of setting examination papers is secure, and protects the examination papers within the process. An ISMS will ensure that all information security aspects are considered and addressed in order to provide appropriate and adequate protection for the examination papers. With the assistance of information security concepts and information security principles, the ISMS can be developed, in order to secure the process of preparing examination papers; in order to protect the examination papers from potential risks. Risk assessment form part of the ISMS, and is at the centre of any security effort; reason being that to secure an information environment, knowing and understanding the risks is imperative. Risks pertaining to that particular environment need to be assessed in order to deal with those appropriately. In addition, very important to any security effort is ensuring that employees working with the valuable information are made aware of these risks, and can be able to protect the information. Therefore, the role players (within the examination paper preparation process (EPPP)) who handle the examination papers on a daily basis have to be equipped with means of handling valuable information in a secure manner. Some of the role players’ behaviour and practices while handling the information could be seen as vulnerabilities that could be exploited by threats, resulting in the compromise in the CIA of the information. Therefore, it is imperative that role players are made aware of their practices and iv behaviour that could result in a negative impact for the institution. This awareness forms part and is addressed in the ISMS.
- Full Text:
- Date Issued: 2016
Information security concerns around enterprise bring your own device adoption in South African higher education institutions
- Authors: Sauls, Gershwin Ashton
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3619 , vital:20530
- Description: The research carried out in this thesis is an investigation into the information security concerns around the use of personally-owned mobile devices within South African universities. This concept, which is more commonly known as Bring Your Own Device or BYOD has raised many data loss concerns for organizational IT Departments across various industries worldwide. Universities as institutions are designed to facilitate research and learning and as such, have a strong culture toward the sharing of information which complicates management of these data loss concerns even further. As such, the objectives of the research were to determine the acceptance levels of BYOD within South African universities in relation to the perceived security risks. Thereafter, an investigation into which security practices, if any, that South African universities are using to minimize the information security concerns was carried out by means of a targeted online questionnaire. An extensive literature review was first carried out to evaluate the motivation for the research and to assess advantages of using Smartphone and Tablet PC’s for work related purposes. Thereafter, to determine security concerns, other surveys and related work was consulted to determine the relevant questions needed by the online questionnaire. The quantity of comprehensive academic studies concerning the security aspects of BYOD within organizations was very limited and because of this reason, the research took on a highly exploratory design. Finally, the research deliberated on the results of the online questionnaire and concluded with a strategy for the implementation of a mobile device security strategy for using personally-owned devices in a work-related environment.
- Full Text:
- Date Issued: 2016
- Authors: Sauls, Gershwin Ashton
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3619 , vital:20530
- Description: The research carried out in this thesis is an investigation into the information security concerns around the use of personally-owned mobile devices within South African universities. This concept, which is more commonly known as Bring Your Own Device or BYOD has raised many data loss concerns for organizational IT Departments across various industries worldwide. Universities as institutions are designed to facilitate research and learning and as such, have a strong culture toward the sharing of information which complicates management of these data loss concerns even further. As such, the objectives of the research were to determine the acceptance levels of BYOD within South African universities in relation to the perceived security risks. Thereafter, an investigation into which security practices, if any, that South African universities are using to minimize the information security concerns was carried out by means of a targeted online questionnaire. An extensive literature review was first carried out to evaluate the motivation for the research and to assess advantages of using Smartphone and Tablet PC’s for work related purposes. Thereafter, to determine security concerns, other surveys and related work was consulted to determine the relevant questions needed by the online questionnaire. The quantity of comprehensive academic studies concerning the security aspects of BYOD within organizations was very limited and because of this reason, the research took on a highly exploratory design. Finally, the research deliberated on the results of the online questionnaire and concluded with a strategy for the implementation of a mobile device security strategy for using personally-owned devices in a work-related environment.
- Full Text:
- Date Issued: 2016
Inhibiting factors to the role of representative council of learners in participative governance of schools: a case study of selected schools in the Qumbu District in Eastern Cape Province of South Africa
- Authors: Poswa, Sakumzi
- Date: 2016
- Subjects: High school students -- Governance Student representative council -- Secondary education
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: http://hdl.handle.net/11260/484 , vital:27277
- Description: This study was conducted in four Qumbu District schools The literature review enabled the researcher to understand the current discourses in terms of learners’ participation in the governance of schools through the Representative Council of Learners Through the methodological application of triangulation, the study produced data on which findings were based and recommendations made Generally, evidence from the collected data reveals issues worth the attention of the researcher and relevant authorities Some of the evidence in this study was that there is need to involve learners in decision making; that the learners who are elected to be members of the RCL should be provided with orientation and training so that they become aware of the content of policy documentations that govern their roles and responsibilities These RCL members are supposed to be considered as potential decision makers and leaders in their schools It is therefore the responsibility of schools and the Department of Education to provide orientation and training for these learners so as to equip them adequately with leadership information and to develop their skills in order for them to be able to play their roles responsibly In concluding, the researcher believes that solutions to the problems identified can be resolved by considering the recommendations for implementation.
- Full Text:
- Date Issued: 2016
- Authors: Poswa, Sakumzi
- Date: 2016
- Subjects: High school students -- Governance Student representative council -- Secondary education
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: http://hdl.handle.net/11260/484 , vital:27277
- Description: This study was conducted in four Qumbu District schools The literature review enabled the researcher to understand the current discourses in terms of learners’ participation in the governance of schools through the Representative Council of Learners Through the methodological application of triangulation, the study produced data on which findings were based and recommendations made Generally, evidence from the collected data reveals issues worth the attention of the researcher and relevant authorities Some of the evidence in this study was that there is need to involve learners in decision making; that the learners who are elected to be members of the RCL should be provided with orientation and training so that they become aware of the content of policy documentations that govern their roles and responsibilities These RCL members are supposed to be considered as potential decision makers and leaders in their schools It is therefore the responsibility of schools and the Department of Education to provide orientation and training for these learners so as to equip them adequately with leadership information and to develop their skills in order for them to be able to play their roles responsibly In concluding, the researcher believes that solutions to the problems identified can be resolved by considering the recommendations for implementation.
- Full Text:
- Date Issued: 2016
Institutional change, institutional isolation and biodiversity governance in South Africa: a case study of the trout industry in alien and invasive species regulatory reforms
- Authors: Marire, Juniours
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/639 , vital:19977
- Description: The world, in recent decades, has witnessed an incalculable surge in global “wicked” policy problems that have long-term, and most often irreversible, impacts, not least terrorism, climate change, biodiversity losses and desertification. Wicked problems are wicked because there is no single epistemological system that can adequately coordinate policy action for addressing them. Literature abounds with international case studies of opposition to national institutions that are designed to put into effect global and regional policies for resolving wicked problems. This raises questions about what constitutes reasonable institutions, how such institutions can be designed and why societies sometimes fail to develop such institutions despite the obvious need for them. As a point of entry into these issues, the thesis adapted and extended the Northean (2007, 2012) macro meta-theoretic framework for studying the violence-development relationship, which focuses on the role of political and economic competition in the emergence of ‘right’ institutions that promote development, while containing violence. The Northean framework conceptualises two mutually exclusive social orders – the limited access order and the open access order – which provide the socio-cultural context for the evolution of specific institutions. The macro meta-theoretic framework was transformed into a micro metatheoretic framework in such a way that the limited access order and the open access order co-existed in the evolution of specific institutions. This reconceptualisation built on Bromley’s (2004, 2006) two realms of public policy: the realm of reasons (legislative-judicial system) and the realm of rules (administrative system) as well as the feminist concept of epistemic violence, which broadened the concept of violence from being exclusively physical to including the sociocognitive. The feminist concept of epistemic oppression logically fitted into, and became a new sub-category of, Commons’ (1899, 1924, 1934) theories of sovereignty and negotiational psychology. The innovations showed that either of these realms can be a limited access order, while the other can be an open access order or both can be open access orders or both can be limited access orders. The conceptual innovations were then used as an interpretive scheme in analysing the evolution of the South African invasive alien species regulatory reforms under the National Environmental Management: Biodiversity Act of 2004, using a case study of the trout sector, which was the most opposed to the reforms. There was a general perception among socioeconomic sectors that utilise invasive alien species that the regulatory reform processes for the governance of such species had institutionally isolated the sectors. Because of this perception, the regulatory reform process was contested, and implementation of the Fifth Chapter of the Act, which deals with the governance of invasive alien species, was delayed for nearly a decade. The thesis evaluated whether institutional isolation existed and how and why it came to be since it has implications for the reasonableness of emerging regulatory institutions, economic performance of sectors and efficient allocation of fiscal resources in institutional design processes. A mixed methods methodology was used, which included data analysis techniques such as semiosis, exploratory factor analysis, econometric estimation and document analysis. Policy documents, an online survey and key informant interviews comprised the data. The findings suggested six dimensions of institutional change that a theory of institutional change might have to address: the origin and continuity of pecuniary institutions; selfreinforcing mechanisms of the limited access policymaking order; succession and disbandment of the limited access policymaking order; exclusivity of negotiations in institutional design; tiers of institutional isolation; and the role of administrative discontinuities. Findings suggested that institutional isolation existed in the regulatory process, manifesting in three forms: administrative isolation, epistemological isolation and sectoral isolation. Administrative isolation was the most complex of the three in that it also involved a less obvious process of institutional isolation in the form of administrative redefinition of opportunity sets that were already legislatively redefined. The mechanisms of institutional isolation through which administrative isolation was sustained were administrative financing of research and careerism. The two mechanisms created a revolving door-type scenario through which invasion biologists supplied the administrative agency with candidates for senior (decision making) positions and the administrative agency, in turn, demanded specific types of knowledge over which the same epistemic community had a monopoly. The revolving door-type scenario was found to ideologically and physically entrench invasion biologists into the regulatory community. The consequence of the entrenchment was institutional hegemony, which manifested itself through the mechanism of epistemic violence insofar as the invasion biologists became the epistemic arbiters about what kinds of ideas and institutions really mattered in the governance of invasive alien species. Econometric estimates suggested that the extent to which an emerging institution is perceived to be reasonable by regulated sectors depends on the extent to which the institution is designed in a participatory and inclusive manner (that is, using integrative knowledge systems), the extent to which the designers used credible evidence and contextualised international evidence as well as the extent to which the emergent biodiversity governance institution was anthropocentric. However, findings suggested that the South African regulatory reform process fell short on all these four dimensions of reasonable institutions, which is characteristic of institutional design process shaped by hegemonic social imaginaries, resulting in institutional isolation. Emerging from the findings are several theoretical insights. Bush’s (1987) concept of institutional spaces under the Veblenian Dichotomy was extended, the result of which was identification of two stable institutional equilibria – one ceremonial and another instrumental. The ceremonial equilibrium was a typical limited access policymaking order and was responsible for the historical and present emergence of regressive institutions. Findings also suggested that the entrenched invasion biologists ceremonially encapsulated the knowledge fund that had been accumulated since the 1980s, which could have facilitated the consensual design of regulatory institutions for invasive alien species without protracted controversy. Findings suggested that a limited access policymaking order could only be disbanded by the intervention of an external sovereign agent (in this case the office of the state president) since the administrative agency, and the epistemic community that advised it, adopted the solutions that were empirically tested and proposed in the 1980s only after the intervention of the external sovereign agent. The instrumental equilibrium repealed the contested prisoner’s dilemma that was characteristic of the policy process and turned it into an assurance policy game by facilitating the identification of common interests. This finding logically links the study to a recent theoretical development in institutional theory – Ordonomics – which focuses on the causality between ideas and institutions. The findings imply that it is possible to design reasonable institutions as long as integrative (transdisciplinary) knowledge systems, including the non-scientific knowledge of the resource users, are incorporated. Integrative knowledge systems facilitate semantic innovations, which create social DNA, but epistemic violence destroys social DNA. They also imply that reliance on unidisciplinary knowledge systems in institutional design induces a large and inefficient transaction cost burden of public policy on the fiscus and private agents alike because of the inevitability of controversy, especially for wicked policy problems.
- Full Text:
- Date Issued: 2016
- Authors: Marire, Juniours
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/639 , vital:19977
- Description: The world, in recent decades, has witnessed an incalculable surge in global “wicked” policy problems that have long-term, and most often irreversible, impacts, not least terrorism, climate change, biodiversity losses and desertification. Wicked problems are wicked because there is no single epistemological system that can adequately coordinate policy action for addressing them. Literature abounds with international case studies of opposition to national institutions that are designed to put into effect global and regional policies for resolving wicked problems. This raises questions about what constitutes reasonable institutions, how such institutions can be designed and why societies sometimes fail to develop such institutions despite the obvious need for them. As a point of entry into these issues, the thesis adapted and extended the Northean (2007, 2012) macro meta-theoretic framework for studying the violence-development relationship, which focuses on the role of political and economic competition in the emergence of ‘right’ institutions that promote development, while containing violence. The Northean framework conceptualises two mutually exclusive social orders – the limited access order and the open access order – which provide the socio-cultural context for the evolution of specific institutions. The macro meta-theoretic framework was transformed into a micro metatheoretic framework in such a way that the limited access order and the open access order co-existed in the evolution of specific institutions. This reconceptualisation built on Bromley’s (2004, 2006) two realms of public policy: the realm of reasons (legislative-judicial system) and the realm of rules (administrative system) as well as the feminist concept of epistemic violence, which broadened the concept of violence from being exclusively physical to including the sociocognitive. The feminist concept of epistemic oppression logically fitted into, and became a new sub-category of, Commons’ (1899, 1924, 1934) theories of sovereignty and negotiational psychology. The innovations showed that either of these realms can be a limited access order, while the other can be an open access order or both can be open access orders or both can be limited access orders. The conceptual innovations were then used as an interpretive scheme in analysing the evolution of the South African invasive alien species regulatory reforms under the National Environmental Management: Biodiversity Act of 2004, using a case study of the trout sector, which was the most opposed to the reforms. There was a general perception among socioeconomic sectors that utilise invasive alien species that the regulatory reform processes for the governance of such species had institutionally isolated the sectors. Because of this perception, the regulatory reform process was contested, and implementation of the Fifth Chapter of the Act, which deals with the governance of invasive alien species, was delayed for nearly a decade. The thesis evaluated whether institutional isolation existed and how and why it came to be since it has implications for the reasonableness of emerging regulatory institutions, economic performance of sectors and efficient allocation of fiscal resources in institutional design processes. A mixed methods methodology was used, which included data analysis techniques such as semiosis, exploratory factor analysis, econometric estimation and document analysis. Policy documents, an online survey and key informant interviews comprised the data. The findings suggested six dimensions of institutional change that a theory of institutional change might have to address: the origin and continuity of pecuniary institutions; selfreinforcing mechanisms of the limited access policymaking order; succession and disbandment of the limited access policymaking order; exclusivity of negotiations in institutional design; tiers of institutional isolation; and the role of administrative discontinuities. Findings suggested that institutional isolation existed in the regulatory process, manifesting in three forms: administrative isolation, epistemological isolation and sectoral isolation. Administrative isolation was the most complex of the three in that it also involved a less obvious process of institutional isolation in the form of administrative redefinition of opportunity sets that were already legislatively redefined. The mechanisms of institutional isolation through which administrative isolation was sustained were administrative financing of research and careerism. The two mechanisms created a revolving door-type scenario through which invasion biologists supplied the administrative agency with candidates for senior (decision making) positions and the administrative agency, in turn, demanded specific types of knowledge over which the same epistemic community had a monopoly. The revolving door-type scenario was found to ideologically and physically entrench invasion biologists into the regulatory community. The consequence of the entrenchment was institutional hegemony, which manifested itself through the mechanism of epistemic violence insofar as the invasion biologists became the epistemic arbiters about what kinds of ideas and institutions really mattered in the governance of invasive alien species. Econometric estimates suggested that the extent to which an emerging institution is perceived to be reasonable by regulated sectors depends on the extent to which the institution is designed in a participatory and inclusive manner (that is, using integrative knowledge systems), the extent to which the designers used credible evidence and contextualised international evidence as well as the extent to which the emergent biodiversity governance institution was anthropocentric. However, findings suggested that the South African regulatory reform process fell short on all these four dimensions of reasonable institutions, which is characteristic of institutional design process shaped by hegemonic social imaginaries, resulting in institutional isolation. Emerging from the findings are several theoretical insights. Bush’s (1987) concept of institutional spaces under the Veblenian Dichotomy was extended, the result of which was identification of two stable institutional equilibria – one ceremonial and another instrumental. The ceremonial equilibrium was a typical limited access policymaking order and was responsible for the historical and present emergence of regressive institutions. Findings also suggested that the entrenched invasion biologists ceremonially encapsulated the knowledge fund that had been accumulated since the 1980s, which could have facilitated the consensual design of regulatory institutions for invasive alien species without protracted controversy. Findings suggested that a limited access policymaking order could only be disbanded by the intervention of an external sovereign agent (in this case the office of the state president) since the administrative agency, and the epistemic community that advised it, adopted the solutions that were empirically tested and proposed in the 1980s only after the intervention of the external sovereign agent. The instrumental equilibrium repealed the contested prisoner’s dilemma that was characteristic of the policy process and turned it into an assurance policy game by facilitating the identification of common interests. This finding logically links the study to a recent theoretical development in institutional theory – Ordonomics – which focuses on the causality between ideas and institutions. The findings imply that it is possible to design reasonable institutions as long as integrative (transdisciplinary) knowledge systems, including the non-scientific knowledge of the resource users, are incorporated. Integrative knowledge systems facilitate semantic innovations, which create social DNA, but epistemic violence destroys social DNA. They also imply that reliance on unidisciplinary knowledge systems in institutional design induces a large and inefficient transaction cost burden of public policy on the fiscus and private agents alike because of the inevitability of controversy, especially for wicked policy problems.
- Full Text:
- Date Issued: 2016
Integrated Algae Pond Systems for the Treatment of Municipal Wastewater
- Authors: Mambo, Mutsa Prudence
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:5960 , http://hdl.handle.net/10962/d1021258
- Description: Integrated algae pond systems are a derivation of the Oswald designed advanced integrated wastewater ponding system, and combine the use of anaerobic and aerobic bioprocesses to effect wastewater treatment. Integrated algae pond system technology was introduced to South Africa in 1996 and a pilot plant was designed and commissioned at the Belmont Valley wastewater treatment works in Grahamstown. Previous studies showed that this system delivered a final effluent superior to most pond systems deployed in South Africa but that it was unable to meet the general standard for nutrient removal and effluent discharge. This study was initiated to re-appraise integrated algae pond systems and to assess the potential of the technology as an effective municipal sewage treatment system. And more...
- Full Text:
- Date Issued: 2016
- Authors: Mambo, Mutsa Prudence
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:5960 , http://hdl.handle.net/10962/d1021258
- Description: Integrated algae pond systems are a derivation of the Oswald designed advanced integrated wastewater ponding system, and combine the use of anaerobic and aerobic bioprocesses to effect wastewater treatment. Integrated algae pond system technology was introduced to South Africa in 1996 and a pilot plant was designed and commissioned at the Belmont Valley wastewater treatment works in Grahamstown. Previous studies showed that this system delivered a final effluent superior to most pond systems deployed in South Africa but that it was unable to meet the general standard for nutrient removal and effluent discharge. This study was initiated to re-appraise integrated algae pond systems and to assess the potential of the technology as an effective municipal sewage treatment system. And more...
- Full Text:
- Date Issued: 2016
Interaction of graphene quantum dots with 4-acetamido-2, 2, 6, 6-tetramethylpiperidine-oxyl free radicals
- Achadu, Ojodomo John, Nyokong, Tebello
- Authors: Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189031 , vital:44810 , xlink:href="https://doi.org/10.1007/s10895-015-1712-0"
- Description: We report on the interaction of graphene quantum dots (GQDs) with 4-acetamido-2,2,6,6-tetramethylpiperidineoxyl (4-acetamido-TEMPO) free radicals. The GQDs were N and S, N doped. The fluorescence quantum yields were higher for the doped GQDs compared to the undoped. The interaction is assessed by spectrofluorimetric, steady state/time resolved fluorescence and electron paramagnetic resonance (EPR) techniques. Fluorescence quenching was observed upon the addition of 4-acetamido-TEMPO to the GQDs. Photoinduced electron transfer (PET) mechanism was suggested as the plausible mechanism involved in the fluorescence quenching in which 4-acetamido-TEMPO acted as the electron acceptor.
- Full Text:
- Date Issued: 2016
- Authors: Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189031 , vital:44810 , xlink:href="https://doi.org/10.1007/s10895-015-1712-0"
- Description: We report on the interaction of graphene quantum dots (GQDs) with 4-acetamido-2,2,6,6-tetramethylpiperidineoxyl (4-acetamido-TEMPO) free radicals. The GQDs were N and S, N doped. The fluorescence quantum yields were higher for the doped GQDs compared to the undoped. The interaction is assessed by spectrofluorimetric, steady state/time resolved fluorescence and electron paramagnetic resonance (EPR) techniques. Fluorescence quenching was observed upon the addition of 4-acetamido-TEMPO to the GQDs. Photoinduced electron transfer (PET) mechanism was suggested as the plausible mechanism involved in the fluorescence quenching in which 4-acetamido-TEMPO acted as the electron acceptor.
- Full Text:
- Date Issued: 2016