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Approaches used by NGOs in managing HIV/AIDS programmes in the Eastern Cape

  • Authors: Budaza, Silakhe
  • Date: 2020
  • Subjects: HIV(Disease)-- Psychological aspects -- Eastern Cape
  • Language: English
  • Type: Thesis , Masters , MA
  • Identifier: http://hdl.handle.net/10948/49775 , vital:41799
  • Description: The purpose of this research study was to explore the interventions NGOs used in addressing the prevalence of HIV/AIDS along with an exploration of the management and causal factors behind project failures and success. Five districts in the province of the Eastern Cape, South Africa were used in the study. The study had three objectives- the first being to identify the various approaches used to manage HIV/AIDS by NGOs; the second was to consider the influence HIV/AIDS policies on the health sector NGOs and finally the third objective of the study was to explore the monitoring and evaluation mechanism set in place to track progress, or lack of, in HIV/AIDS programs. The research design followed a qualitative methodology and data was gathered from ten participants through semi-structured interviews and supported by a document analysis of existing HIV and AIDS policies from both a national and provincial level which were qualitative. The findings showed that a lack of adequate or delayed funding affected the overall performance of NGOs as well as approaches such as home-based care and educational support programs. Resource mobilization and fundraising ought to be diversified so that there is a committed and varied pool of funds to enable the execution of HIV/AIDS services and programs. The government and other stakeholders should build on local capacity to implement these various programs and build financial, social and organizational sustainability.
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  • Date Issued: 2020

Approaches used by NGOs in managing HIV/AIDS programmes in the Eastern Cape

  • Authors: Budaza, Silakhe
  • Date: 2020
  • Subjects: Non-governmental organizations -- South Africa , Disease management -- South Africa -- Eastern Cape
  • Language: English
  • Type: Thesis , Masters , MA
  • Identifier: http://hdl.handle.net/10948/50457 , vital:42169
  • Description: The purpose of this research study was to explore the interventions NGOs used in addressing the prevalence of HIV/AIDS along with an exploration of the management and causal factors behind project failures and success. Five districts in the province of the Eastern Cape, South Africa were used in the study. The study had three objectives- the first being to identify the various approaches used to manage HIV/AIDS by NGOs; the second was to consider the influence HIV/AIDS policies on the health sector NGOs and finally the third objective of the study was to explore the monitoring and evaluation mechanism set in place to track progress, or lack of, in HIV/AIDS programs. The research design followed a qualitative methodology and data was gathered from ten participants through semi-structured interviews and supported by a document analysis of existing HIV and AIDS policies from both a national and provincial level which were qualitative. The findings showed that a lack of adequate or delayed funding affected the overall performance of NGOs as well as approaches such as home-based care and educational support programs. In addition, the negative stigma associated with HIV/AIDS has been a looming issue since 2004 which continues to undermine efforts of NGOs in their means to manage HIV/AIDS. The consequences of stigma from the findings are treatment adherence issues and little to no attendance of HIV/AIDS programs provided by the respective NGOs. Effective planning and management along with capacitated staff and volunteers increased the positive outcome of HIV/AIDS programs and services offered by the NGOs. From the study findings, it is recommended that the planning of HIV/AIDS approaches should consider resource planning to avoid abandoning projects midway due to a lack of resources. The management and monitoring of NGOs within the health sector, dealing with epidemics such as HIV/AIDS need to build on flexibility in implementation and have effective risk assessments in place as a contingency, so that corrective action is taken. Resource mobilization and fundraising ought to be diversified so that there is a committed and varied pool of funds to enable the execution of HIV/AIDS services and programs. The government and other stakeholders should build on local capacity to implement these various programs and also build financial, social and organizational sustainability.
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  • Date Issued: 2020

Arid-adapted paradiaptomid copepods contribute to mosquito regulation

  • Authors: Cuthbert, Ross N , Wasserman, Ryan J , Dalu, Tatenda
  • Date: 2020
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/443260 , vital:74103 , https://hdl.handle.net/10520/ejc-afzoo-v55-n3-a1
  • Description: We are writing to describe the predatory potential of calanoid copepods for the regulation of mosquito larval populations in aquatic environments. Mosquito-borne diseases continue to drive unparalleled human morbidity and mortality (Ferguson 2018), and directly threaten other wildlife (George et al. 2015). This disease burden is most concentrated in Sub-Saharan Africa, where aquatic habitats exploited by mosquitoes are often temporary and, under natural conditions, characterised by arid-adapted ecological communities. These communities can be predator rich, contributing to the regulation of aquatic larval mosquito populations and therefore the adult vectors of the diseases at the landscape scale. A newly described southern African copepod species, Lovenula raynerae Suárez-Morales, Wasserman and Dalu 2015 (Paradiaptominae) (Figure 1), has been identified as an efficacious predatory agent for the natural regulation of medically important mosquito populations in temporary aquatic environments (Cuthbert et al. 2018).
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  • Date Issued: 2020

Assessing community structure and trophic interrelationships in three differently impacted headwater streams in the AmatholeWinterberg freshwater ecoregion, South Africa

  • Authors: Matomela, Nonjabulo Happy
  • Date: 2020
  • Subjects: Stream ecology -- South Africa -- Eastern Cape , Freshwater animals -- Ecology -- South Africa -- Eastern Cape , Kat River (South Africa) -- , Lushington River (South Africa) , Elands River (South Africa) , Eyre River (South Africa) , Food chains (Ecology) -- South Africa -- Eastern Cape , Water quality -- South Africa -- Eastern Cape , Land use -- South Africa -- Eastern Cape
  • Language: English
  • Type: text , Thesis , Masters , MSc
  • Identifier: http://hdl.handle.net/10962/147653 , vital:38658
  • Description: Afromontane regions represent some of the highly threatened ecosystems on the planet as they harbour endemic and often relic freshwater fauna. These ecologically sensitive ecosystems have been altered by multiple impacts, including invasion by non-native fishes, replacement of diverse indigenous vegetation with monoculture plantations, agricultural and mining activities, hydrological modifications, and degradation of instream habitats, with potential detrimental effects on aquatic community structures and food web dynamics. The aim of the present study was to compare spatio-temporal patterns of macroinvertebrate and fish communities as well as food web dynamics in three differently impacted headwater tributaries of the Kat River in the Amathole-Winterberg freshwater ecoregion in the Eastern Cape Province of South Africa. The upper Kat River catchment was the ideal model for purposes of the present study as it contains streams with varying degrees of human impact. The streams considered in the present study were (i) the Eyre River which was considered to closely represent near-natural conditions as it is the least impacted stream in this catchment, with the riparian zone dominated by relatively intact and diverse native woody vegetation, (ii) the Elands River whose catchment has been altered by agricultural activities, and (iii) the Lushington River, whose riparian zone has been heavily invaded by black wattle. The three headwater streams were generally distinguished based on the physical-chemical variables. The Elands River was characterised by high conductivity and total dissolved solids (TDS). In addition, the Elands River was more alkaline and relatively warmer than the other two rivers. This suggested the negative influence of agriculture activities on the water quality in the Elands River. In general, the Lushington and Eyre rivers had comparable physical and chemical variables. However, the Lushington River was generally characterised by low streamflow, likely as a consequent of black wattle which is known for altering hydrological regimes of streams .The Eyre River and Lushington River were comparable in terms of macroinvertebrate richness and diversity, whereas the Elands River was characterised by low macroinvertebrate diversity and richness. Redundancy analysis indicated that the macroinvertebrate communities were mostly influenced by seasonality, with land-use accounting for a small but significant difference in community composition. In comparison, the generalised linear mixed-effects models (GLMMs) showed that chubbyhead barb abundance was significantly influenced by land-use patterns. Evaluation of food web dynamics using stable isotope analysis revealed that the food web structure in the three rivers differed substantially as a result of land-use. Specifically, the Eyre River was characterised by less variation in stable isotope values of basal food sources and consequently, the consumer groups had a narrow isotopic breadth. In contrast, the Elands River was characterised by a wide variation in basal food sources and therefore, a wider isotopic breadth for consumers. The Lushington River was spatially variable in terms of basal sources and isotopic breadth for consumers. The study concluded that food webs and trophic interrelationships were a more informative indicator of land-use than community structure was in evaluating the impact of land-use patterns on aquatic communities. In addition, future studies should seek to investigate food webs interrelationships in addition to community structure to infer a more conclusive river assessment.
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  • Date Issued: 2020

Assessing factors that mitigate business risks in the operations of emerging black-owned businesses in Mthatha, Eastern Cape

  • Authors: Bovungana, Afrika Khanyiso
  • Date: 2020
  • Subjects: Business enterprises, Black
  • Language: English
  • Type: Thesis , Masters , MBA
  • Identifier: http://hdl.handle.net/10948/47502 , vital:40121
  • Description: The study sought to assessfactors that mitigate business risks in the operations of emerging black-owned businesses in Mthatha, Eastern Cape. Small businesses in the country are significant contributorsto the South African economy,as they provide employment and development opportunities to disadvantaged communities. Many of these businesses are operationalbut have no formal systems in place to operate effectively. The lack of proper operating procedures can result ininefficiencies that often lead to the collapse and eventual failure of these businesses. Van Vuuren,a professor at the University of Pretoria,mentionedin a round table dialogue that in South Africa the early stage entrepreneurial activity rate has been recorded as9.2% whereas in similar developing economies such as Brazil early stage entrepreneurialactivity isapproximately 40%. The study utilised a quantitative research design and employed a Likert scale questionnaire on a sample of 64 black-owned small, medium and micro enterprises (SMMEs) chosen by means of a random probability samplingmethod. QuestionPro was used to analyse the data and discuss the findings of the study.The various factors identified and highlighted indicate the integral challenges faced by the black-owned SMMEs remain prevalent. The success or failure is dependent on dynamic interventions that are taken into consideration and implemented for the improvement of the environment and business life cycle of black-owned businesses.
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  • Date Issued: 2020

Assessing invasive alien aquatic plant species, phytoremediation effects using biological indicators in the Swartkops River system

  • Authors: Tshithukhe, Getrude
  • Date: 2020
  • Subjects: Aquatic weeds -- Biological control -- South Africa -- Eastern Cape , Alien plants -- Biological control -- South Africa -- Eastern Cape , Phytoremediation -- South Africa
  • Language: English
  • Type: text , Thesis , Masters , MSc
  • Identifier: http://hdl.handle.net/10962/167665 , vital:41501
  • Description: Pollution effluents in freshwater ecosystems are becoming increasingly ubiquitous as a result of cumulative anthropogenic activities, such as wastewater treatments works, and industrial, agricultural and mining activities. These activities are more noticeable in urban river atchments where there is greater human population densities and industrial developments. The ecological effects of anthropogenic activities on freshwater ecosystems include: excessive deposition of contaminants such as nutrients, pharmaceuticals, microplastics and other chemicals, which change physicochemical properties, causing a decline in aquatic biodiversity. These effects, impact negatively on the resilience of freshwater, making the systems vulnerable to invasion by alien aquatic plants. Ultimately, the loss of local biodiversity associated with the invasive alien aquatic plants (IAAP) results in a loss of some ecosystem goods and services. The Swartkops River system, Eastern Cape Province, drains most of the neighbouring formal and informal settlements, agricultural lands and industries, and hence is exposed to water pollution from human activities along the river catchment. Various water quality assessments are needed to evaluate the extent of pollutants and their impacts on the river ecosystem. Phytoremediation is one approach employed internationally for removing harmful nutrients and chemicals in freshwater ecosystems. Most studies measure the success of phytoremediation through measuring the reduction of contaminants in water or soil chemistry in mesocosm settings, which may not take into account all the important environmental factors that exist in the field. The present study assesses the phytoremediation potential of Pontederia (Eichhornia) crassipes and Salvinia molesta by evaluating water and sediment chemistry, periphyton and aquatic macroinvertebrate community recovery along seven field sites (excluding IAAP species mats sites) located upstream and downstream IAAP species mats on the Swartkops River between April and September 2018. Water and sediment samples were collected once monthly on ten seven field sites, including the IAAP species mat sites. Periphyton and aquatic macroinvertebrates were collected on seven sites, excluding the IAAP mat sites. Pontederia crassipes and S. molesta infestation in Swartkops River showed positive phytoremediation results and improved some water and sediment chemistry in the downstream treatments as compared to upstream treatments. Although there were some fluctuations with some variables, important water and sediment chemistry were reduced downstream. By contrast, biological assessment results did not show any response to the presence of IAAP species and phytoremediation. Periphyton and aquatic macroinvertebrates diversity and community assemblages were more influenced by water quality. Although IAAP species did provide improvement in water and sediments chemistry, multiple effluent point and non-point sources in Swartkops outpaced phytoremediation. Taxa evenness and relative taxa abundance showed significant differences between the upstream and downstream sites, however taxa richness and Shannon’s diversity showed no significant differences, indicating no relative recovery in biodiversity for either periphyton or aquatic macroinvertebrates. Similarly, the upstream and downstream sites showed similar periphyton and aquatic macroinvertebrates assemblages structure, all dominated by pollution tolerant taxa, thus indicating no functional diversity improvement down river; because of improvement in water chemistry downstream sites, it was expected that periphyton and aquatic macroinvertebrates assemblage structure would also improve at these downstream sites.It is possible that the phytoremediation process is outpaced by effluent discharges, given the multiple sources and distance between upstream and downstream mat sites. The study showed phytoremediation potential but the results were not indicated by biological indicators. A replica study conducted on a moderately disturbed river system is recommended to measure the success and recovery of biological indicators and assemblage composition following IAAP species phytoremediation; a moderately disturbed river compared to a largely disturbed river will broaden findings and look at differences for a wider application of phytoremediation.
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  • Date Issued: 2020

Assessing the implementation of long-acting reversible contraceptive implant, Implanon NXT, roll out in East London, Eastern Cape, South Africa.

  • Authors: Mdingi, Mildred Mandisa
  • Date: 2020
  • Subjects: Primary health care
  • Language: English
  • Type: Thesis , Masters , MPH
  • Identifier: http://hdl.handle.net/10353/18452 , vital:42267
  • Description: Background: In 2014, South African Department of Health (SADOH) initiated use of Implanon NXT, a type of implant in addition to long-acting reversible contraceptives available in the country to expand contraceptives options for women of reproductive age. After its introduction, there were reports on early removals and frequent side effects. It is therefore vital to identify how successful the implementation of this method was in particular in East London area. Objectives: The purpose of this study was to evaluate how successful the implementation of Implanon NXT roll out was in East London, Eastern Cape. Additionally, the study also aimed to understand the views health care providers have of the Implanon NXT. Methods: A retrospective crosssectional design using existing data from family planning registers and distribution of questionnaires to Health Care Providers responsible for insertion and removal of the method (HCP). Results: February 2014 to March 2019, 1238 Implanon NXT insertions were done and only 266 removals in one study site. Out of the 266 participants, 67.7% of the participants removed the Implanon for reasons other than ill health (side effects), while the remaining 32.3% had experienced side effects and opted for early Implanon removal. Bleeding was the most common side effect reported by 44 of 266 (16.5%) participants. The health care providers who completed questionnaires for this study were overall confident in providing the Implanon NXT services. Conclusion: Implementation of a new contraceptive method requires clear standardised policies and guidelines on counselling and management of side effects. Findings of this study are reassuring that Implanon NXT had a role to play in prevention of unintended pregnancies. Implementation and rollout in one site reviewed has been demonstrated to be successful. The respondents in this study possesses knowledge about the Implanon NXT.
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  • Date Issued: 2020

Assessing the Social Sustainability of Wind Energy in the Karoo

  • Authors: Hechter, J P
  • Date: 2020
  • Subjects: Wind power -- South Africa -- Karoo
  • Language: English
  • Type: Thesis , Masters , MSc
  • Identifier: http://hdl.handle.net/10948/48378 , vital:40854
  • Description: Background: In an ecologically conscious world, the need for sustainable development and the need to produce alternative energy is at the forefront of discussions. South Africa has been witnessing to a surge in wind energy developments in recent years. Although, environmental impacts often enjoy more emphasis, social impacts are equally important. Recently social sustainability was seen as an integral part of sustainable development for the future and can no longer be ignored. Wind energy is pathway towards sustainable development but can have detrimental impacts on social sustainability. On the one hand wind energy is said to impact culture, sense of places and cause unrest in a community, however, on the other hand it is said to be socially sustainable to the point where wind energy is incorporated into local culture and not to mention the employment opportunities it can create. This is particularly important for vulnerable communities found in the Karoo, where unemployment is very high. Purpose/ Aim: The aim of this study was to assess the social sustainability of a wind energy project in the Karoo by constructing a theoretical assessment model designed to produce appropriate and specific social indicators. Methodology: A literature review was undertaken to gain insights into the social sustainability of wind energy which also served as the theoretical backbone for the model and assessment parameters. The assessment model produced 10 indicators which was used as interview schedule with key stakeholders in the study area. A total of 31 qualitative interviews were conducted and produced a good data set. Findings: The results from this study show that here was no significant negative impact reported with regards to social sustainability. The wind developer is committed to the community based on the various social initiative funded by it. Although a definite positive impact and improvement in terms of social sustainability is evident in the area, there is still a long way to go as many outcomes set by the wind developer is yet to achieved.
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  • Date Issued: 2020

Assessment of taste masking of captopril by ion-exchange resins using electronic gustatory system

  • Authors: Chikukwa, Mellisa T R , Wesoly, Malgorzata , Korzeniowska, Aleksandra B , Ciosek-Skibinska, Patrycja , Walker, Roderick B , Khamanga, Sandile M M
  • Date: 2020
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/184710 , vital:44265 , xlink:href="https://doi.org/10.1080/10837450.2019.1687520"
  • Description: The objective of the study was to mask the unpleasant taste of captopril (CPT). Taste masking was achieved by complexation of CPT with a basic ion exchange resin, Dowex® 66, using the batch method. Dowex® 66 was used for the adsorption of CPT, and physical and chemical parameters of the CPT resinates complex were evaluated. A central composite design was used to generate the experiments for the manufacture of resinates using different process and formulation variables. In vitro dissolution studies were performed for 2 h in 0.01N HCl (pH 1.6) using USP Apparatus I. The compatibility of CPT and the resin was evaluated by Fourier transform infrared (FTIR), differential scanning calorimetry (DSC), and powder X-ray diffraction (PXRD). The resinates were evaluated for micromeritic properties and further characterised using FTIR, DSC, and PXRD. Response surface methodology was used to determine the significance of input variables on the CPT content and release. The CPT resin ratio was found to have a significant impact on content of the resinates and on CPT release. The formulations were also studied for taste masking ability by means of an electronic gustatory system – electronic tongue.
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  • Date Issued: 2020

Assessment of the implementation of the citizen centric strategies for social grant service delivery :Chris Hani District

  • Authors: Danster, Siyabulela
  • Date: 2020
  • Subjects: South African Social Security Agency -- South Africa -- Chris Hani District
  • Language: English
  • Type: Thesis , Masters , MA
  • Identifier: http://hdl.handle.net/10948/46692 , vital:39609
  • Description: This study aimed to assess the implementation of citizen centric strategies for social grant service delivery in the Chris Hani District and if SASSA is still living up to its promise. SASSA claims it will always pay the right social grant, to the right person, at the right time and place. This study aimed to understand and assess the different strategies of SASSA towards enhancing citizen experience in delivering social grants. The study’s objective was to assess citizen experience regarding the SASSA social grant payment systems, the social grant application processes, and SASSA communication and advocacy programmes. To conduct this study, a qualitative research methodology was employed. The population sample comprised of SASSA officials in the Chris Hani District. Semi-structured interviews were conducted with SASSA officials. The findings of this study reveal that SASSA did well to improve application turnaround time from 90 days to one day. Even so, payment methods must be improved. The recommendations suggest that SASSA should consider insourcing the function of paying social grants and consider opening the closed pay-points, as beneficiaries are struggling to travel to the remaining opened pay-points. The findings also proposed aligning the SocPen and MIS.
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  • Date Issued: 2020

Assessment of the microbial quality of various domestic rainwater harvesting systems and the suitability of a nano based treatment method

  • Authors: Malema, Mokaba Shirley
  • Date: 2020
  • Language: English
  • Type: thesis , text , Thesis , Doctoral , PhD
  • Identifier: http://hdl.handle.net/10962/110218 , vital:33249 , https://dx.doi.org/10.21504/10962/110218
  • Description: Thesis (PhD)--Rhodes University, Faculty of Science, Chemistry, 2020.
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  • Date Issued: 2020

Associations between family history of diseases of lifestyle, lifestyle behaviour and anthropometric nutritional status of pre-school children in ECD centres in the Nelson Mandela Bay Municipality

  • Authors: Wilson, Teresa Margaret
  • Date: 2020
  • Subjects: Nutrition--Evaluation
  • Language: English
  • Type: Thesis , Masters , MSc
  • Identifier: http://hdl.handle.net/10948/46344 , vital:39602
  • Description: Introduction: Childhood overweight and obesity is an escalating global health issue. In Africa, overweight and obesity prevalence in children has nearly doubled since 2000(World Health Organisation, 2018).TheSANHANES-1 study (2013) identified that overweight and obesity in were most prevalent in urban informal areas of South Africa, with approximately a quarter of the children classified as overweight or obese (Shisana et al., 2013).In the Nelson Mandela Bay Municipality(NMBM), a double burden of disease was identified in the lower socio-economic population (Phekana et al., 2016). This study and others recommended further study into the contributing factors and behaviours which play a role in the development of overweight and obesity in children. These include household dietary intake, family history of lifestyle diseases, as well as the children’s and parental physical activity and sedentary time (Zhang et al.,2016).Aim: The aim of the study was to determine the associations between family history of diseases of lifestyle, lifestyle behaviour and anthropometric nutritional status of pre-school children in NMBM to describe underlying causes of childhood overweight and obesity.Methods: A cross-sectional design, using a quantitative approach, was used for this study(Ethics approval: H18-HEA-DIET-004). The study population included adult parents and/or caregivers of children from urban areas of Nelson Mandela Bay Municipality attending crèches and schools in these areas, in the age group from birth to 96 months (8 years). Randomised cluster sampling of crèches and schools from an existing database of anthropometrical data of children attending these crèches and schools in the area was done and a final sample of n=155obtained. With the assistance of a trained fieldworker, respondents completed a questionnaire detailing the family history of lifestyle diseases, physical activity levels and sedentary screen time behaviours, and a graphical adjusted version of a household dietary diversity questionnaire. Data about children’s activity levels in the preschool/creche environment was collected by the fieldworker by assessing the ECD centres’daily activity schedules. The anthropometric data of the children of the respondents was accessed from an existing database of these measurements. The data was described using means and standard deviations. Inferential statistics determined any existing associations between these underlying influences of childhood obesity.Results: Only 2% (n=3) of the children were underweight and 12% (n=9) were at risk of becoming underweight as classified by WAZ. HAZ scores identified26% (n=40) of the children at risk of becoming stunted, and 6% (n=9) of the children were already stunted. WHZ classified5% (n=8)of the children as overweight and 5% (n=8)as obese. A further 22% (n=34) of the children were at risk of becoming overweight.BMI/age classificationidentified25% (n=38) of the children as overweight and a further 12% (n=19) as obese. Out of the sample, 12%(n=17) of mothers and 8% (n=7) of fathers were categorised as overweight-to-obese according to the SA specific waist circumference(WC)cut-offs. Out of the children, 15% (n=22) have at least one parent who was overweight-to-obese. Traditional WC categories were classified48% (n=67) of the mothers as overweight-to-obese and at high risk for metabolic syndrome. Of all the lifestyle diseases, hypertension was the most prevalent with 29% (n=41) of households having at least one parent with hypertension. Parental physical activity was grossly overestimated, and the results found to be invalid. The Diet Variety and Frequency score resulted in a mean of 65.00 (n=154, SD=27.37) out of a possible 100 for the households in this sample, and junk food was consumed on three to four occasions per day in 32% (n=49) of households. There were no significant associations found between the parents’ variables and underweight children. Statistically small to medium effect associations were found between parental weight (both SA specific and traditional categories) and overweight children (classified by WHZ and BMI/age). Conclusions and recommendations: The prevalence of overweight and obesity among children in the NMBM was high. The only possible underlying cause of childhood overweight and obesity in pre-school children in the NMBM that could be determined by this study was parents’ weight classified by WC. However, it must be reiterated that due to the cross-sectional nature of the study, an association does not immediately mean causation, and the results are not adequate to rule out other underlying factors influencing childhood obesity. It is recommended that the results of the study are used to incentivise the final implementation of all the intervention targets laid out in the Strategic Plan for the Prevention and Control of Obesity in South Africa 2015-2020 in NMB, and for the development of the future obesity strategy after 2020. The results have shown the necessity for future health interventions to be targeted at the family as a unit.
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  • Date Issued: 2020

Attention-deficit/hyperactivity disorder (ADHD) in South Africa: diagnosis and treatment from childhood to adulthood

  • Authors: Munasur-Naidoo, Ashmitha Premchand
  • Date: 2020
  • Subjects: Attention-deficit hyperactivity disorder
  • Language: English
  • Type: Thesis , Doctoral , PhD
  • Identifier: http://hdl.handle.net/10948/46398 , vital:39603
  • Description: Background: Historically Attention-Deficit/hyperactivity disorder (ADHD) was, considered to be a condition that affected mainly children. Over a period of time, there has been a greater understanding to recognize that this condition is also present in the adult population. Globally, treatment for adults has been established as is evident from the various guidelines available. In South Africa, however,healthcare is split into the public and private sectors, which results in differences in the extent of diagnosis and treatment for adults with ADHD.Aim: The primary aim of the study was to evaluate ADHD in South Africa from childhood to adulthood and to determine to what extent adults are being diagnosed and treated.Method: This study comprised of two facets, namely, a drug utilization review and a questionnaire survey. The first part comprised of a retrospective drug utilization study evaluating the consumption and cost of medication used in the treatment of ADHD. The questionnaire was undertaken using a survey methodology amongst selected healthcare professionals in South Africa involved in the diagnosis and treatment of adult ADHD. The data generated from this study together with available guidelines was assessed and a proposed framework for the treatment and diagnosis of adult ADHD was developed for use in the South African public healthcare sector. Results: Based on the registered medication available to treat ADHD, the consumption of methylphenidate and atomoxetine in the private healthcare sector using the Intercontinental Marketing Service database from 2013 to 2016was established. Despite the controversy regarding stimulant medication, methylphenidate was shown to be the medication of choice in South Africa. The consumption of methylphenidate (95.85%) was higher when compared to atomoxetine (4.15%) in 2013 and very slight changes were observed in 2016 were the consumption was 96.40% and 3.60%, respectively. Similarly, over a four-year period, the spend on ADHD medication increased in 2013 to 2016 by 62.63%. Furthermore, the market share for ADHD is dominated by extended-release methylphenidate tablets (59.53%). The questionnaire survey amongst selected healthcare professionals in South Africa involved in the diagnosis and treatment of adult ADHDhighlighted the tools used for diagnosis, pharmacological and non-pharmacological treatment options, which treatment has been found to be most successful, difference in treatment between genders, incorporation of supplementation into the management of patients, difficulties experienced by patients and which co-morbid conditions were also prevalent with ADHD. Based on the data collated in this study and an evaluation of the available guidelines, a framework for treatment of adult patients in the public healthcare sector has been proposed for South Africa at a provincial and national level. Conclusion: In South Africa treatment for ADHD is increasing in the private healthcare sector. The cost and consumption of methylphenidate and atomoxetine has risen over a short period. The treatment of adults in the private sector has also garnered interest, however, the public sector has not yet published guidelines enabling access to diagnosis and treatment for these adult patients. Given the chronic, costly, and debilitating nature of this condition more needs to be done to assist those affected by it. Further studies in this area of neuropsychiatry in South Africa is required to enable access to diagnosis and treatment in the public healthcare sector.
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  • Date Issued: 2020

Attentive amelioration: developing and evaluating an applied mindfulness programme for psychologists

  • Authors: McGarvie, Susan
  • Date: 2020
  • Subjects: Attentive Amelioration Programme , Mindfulness (Psychology) , Psychotherapy -- Practice , Counseling -- Practice , Medical professionals -- Mental health
  • Language: English
  • Type: text , Thesis , Doctoral , PhD
  • Identifier: http://hdl.handle.net/10962/166186 , vital:41336
  • Description: It is readily accepted that healthcare in many third world countries is in crisis, but interestingly, even in wealthy first world countries, many healthcare systems are stretched to their limits, as fewer people choose to follow a career in healthcare and more staff members struggle under the pressures of an overextended system (Krasner, et al., 2009). Ways to improve healthcare practitioner wellbeing is thus a relevant and widely investigated topic (McCann et al., 2013), which has, until recently, been aimed at reducing the negative symptoms associated with poor wellbeing, such as stress and burnout. More recently, there has been burgeoning interest in the effects and potential benefits of mindfulness practice to wellbeing, especially in developed English-speaking countries like the UK, Canada, USA, Australia, as well as in Europe. The aim of this study was to contribute to this body of literature by proposing a more personalised and person-centred means to support and improve wellbeing. It was guided by an overarching research question, about the benefits of a mindfulness-based wellness course for practicing psychologists. This study is a mixed-methods narrative inquiry which employs both Action Research (AR) and Programme Evaluation methods. It involved the design, implementation and evaluation of a mindful-wellness programme, subsequently named the Attentive Amelioration programme. Ten participants were purposively recruited and enrolled in the programme, which ran over eight weeks and included coaching and blended learning facilitation methods, including: an introductory workshop (with a pedagogical mix of lecture, group discussion, practical activities, learners manual and YouTube clips), individual and group coaching sessions, and an online learning programme. The findings suggest that psychologists do experience a great deal of stress and perceived levels of burnout are high, even if the scores on the pre- and post- intervention self-assessment scales do not entirely support this perception. This study found that participants were open to and engaged with mindfulness training and practice and sustained that practice for several months post-intervention. Finally, overall findings suggest that while the Attentive Amelioration programme was effective as a means to cultivate and develop mindfulness, self-compassion and overall wellbeing in the short-term, further investigation is required to determine the sustainability of the effects over the long-term. The findings of this study support the overall aims of the study in that it has found that the participating psychologists found the Attentive Amelioration programme to be beneficial, supportive and even therapeutic. By contributing to and supporting findings of existing research, that suggest that a mindfulness-based coaching programme would be beneficial to psychologist wellbeing and therapeutic proficiency, it serves to advocate for mindfulness as a means to improve and sustain psychologist wellbeing..
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  • Date Issued: 2020

Attitudinal difference surveys perpetuate harmful tropes: A comment on Nattrass

  • Authors: Rosenberg, Eureta , Le Grange, Lesley
  • Date: 2020
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/370129 , vital:66300 , xlink:href="https://doi.org/10.17159/sajs.2020/8469"
  • Description: We reply to the article, ‘Why are black South African students less likely to consider studying biological sciences?’, authored by University of Cape Town (UCT) researcher Nicoli Nattrass1 and published in the South African Journal of Science on 27 May 2020. At the time of writing our reply the article had already received sharp criticism from the Black Academic Caucus at UCT and in a statement released on 5 June 2020, the UCT executive distanced itself from the content of the paper, inviting rigorous, respectful review of the published research. Nattrass’ article1 follows two papers published in 2019 by scholars associated with South African universities, both of which were widely denounced for the racist undertones of their content. The first article was authored by Stellenbosch University researchers who reported on low cognitive functioning of coloured women linked to education levels and lifestyles2 ; see comment by Le Grange3 . The second article was co-authored by an adjunct professor at UCT and examined the role of cognitive ability or intelligence on slave exports from Africa4 . These publications gave rise to a broader debate on enduring racism in science and the re-ascendency of race science internationally. In this reply, we focus on the methodology of attitudinal survey used for the study reported by Nattrass (and by many other scientists). There are two lines of argument that we weave together: the quality of the research as reported, and problems inherent to comparative attitudinal survey research (regardless of how well it is executed). It should be noted that the Black Academic Caucus at UCT has also critiqued the research design, identifying many of the points we make here, and they have additionally included a discourse analysis of the paper (circulated via e-mail). To demonstrate how problematic a survey design can be, particularly when it is not rigorously executed, we share data and observations that counter the apparent findings of Nattrass’ study. We then argue that the publication of this research, in this manner, is detrimental to the biodiversity sector in which the tropes being perpetuated, can cause enormous harm. In the process we hope to encourage scientists to be more reflexive about their methodology, and we encourage the South African Journal of Science to publish works that are worthy of the young people of this country - research in which they can recognise themselves, rather than being forced to look at reductionist portrayals, legitimised under the banner of science.
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  • Date Issued: 2020

Audio-Visual and Cyber Evidence in the Context of Criminal Law

  • Authors: Madzika, Koshesayi
  • Date: 2020
  • Subjects: Electronic evidence -- Law and legislation -- South Africa
  • Language: English
  • Type: Thesis , Masters , LLM
  • Identifier: http://hdl.handle.net/10948/47380 , vital:39967
  • Description: In the past decade technology has advanced significantly and at a very rapid pace. This advancement and rapid growth of technology has affected many aspects of life, including legal systems. An area of law particularly affected by the rapid changes in technology is the law of electronic evidence, especially as far as criminal matters are concerned. This is largely due to an increase in crimes committed over the internet. The growth of technology, such as cyber communications and mass media, has made audio visual and electronic messages important forms of evidence. The purpose of this research is to show the complications that technology has brought about as far as electronic evidence in the context of criminal law is concerned. It is acknowledged that South Africa has an existing legislative framework regulating electronic evidence, but it is submitted that there are lacunae in such legislation. The aim of the dissertation is therefore to expose the lack of adequate regulation in South Africa in dealing with electronic evidence. A further aim of the research is to seek to provide solutions to problems related to the regulation of electronic evidence. It is important to determine the current laws regulating electronic evidence in order to expose the lacunae within those laws. An outline of the current legal framework regulating electronic evidence shall be given. This consists of the historical background on the admissibility of electronic evidence; the constitutional basis for admitting such evidence and legal principles governing electronic evidence. Inadequate regulation of electronic evidence is a serious problem, as technology has overtaken some areas of the physical world. The criminal justice system has also been affected especially in the admissibility of electronic evidence. The problems regarding electronic evidence in criminal law matters shall be fully assessed in order to reflect how the criminal justice system has been affected and the consequences of inadequate regulation. In seeking solutions to the problems of inadequate regulation of electronic evidence, reliance is placed on recommendations by the South African Law Reform Commission; international and foreign law. A conclusion is drawn from the dissertation that, whilst technology has been rapidly advancing, the South African law regulating electronic evidence has remained largely unchanged, rendering it incapable of sufficiently regulating matters in which electronic evidence plays a key role. The demand for adequate legislation on electronic evidence is therefore apparent in this regard.
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  • Date Issued: 2020

Audit of intravenous antifungal therapy used for Candida infections at a South African private hospital

  • Authors: Van Dyk, Jacklyn Kate
  • Date: 2020
  • Subjects: Candidiasis
  • Language: English
  • Type: Thesis , Masters , MPharm
  • Identifier: http://hdl.handle.net/10948/46380 , vital:39600
  • Description: The epidemiological landscape of the candida species has changed with the emergence of MDR strains globally and in South Africa. The aim of this study was to critically evaluate the compliance to guidelines in the use of intravenous antifungal therapy when treating invasive Candidainfections in a South African private hospital.Objective One was to determine the prevalence of Candida auris(C.auris) in the sample. Objective Two examined the relationship between high-risk patients and positive microbiological cultures. Objective Three studied the prescribing utilisation of the intravenous antifungalsin the form of a clinical audit. Objective Four compared these prescribing patternsto current guidelines by evaluating whether the antifungal course was non-compliant, of suboptimal compliance or compliant. Objective Five was to design a protocol for ward pharmacists to use when assessing antifungal treatment for candidiasis. The research design consisted of a retrospective, non-experimental, cross-sectional analysis of intravenous antifungal use in the management of systemic Candida infections in a private sector hospital in the Gauteng province, South Africa.A positive research paradigm with a quantitative clinical audit was used in this study. The most prevalent species cultured was C.auris with 31 of the 77 positive cultures. Risk stratifying patients was validated with 70% of high risk patients (Candida Score >2.5 and positive β-D-glucan) having a corresponding positive culture. Echinocandins were the most frequently utilised antifungal class, with caspofungin being the most used antifungal in the sample. The average duration of therapy for the echinocandins ranged between 11 and 16 days. Compliance to guidelines was evaluated accordingto: reason for initiation; drug choice and drug dose. Three levels of compliance were determined: non-compliant, sub-optimal compliance and compliant. xivThe overall compliance,according to recommended treatment guidelines,was found to be suboptimal, with anidentified need foranintervention which targets thedosing of the antifungals used. In conclusion, the research findings highlight the importance of reviewing antifungal prescribing habits and the need for antifungal stewardship programmes.
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  • Date Issued: 2020

Awareness, knowledge and practices with regards to alcohol use of pregnant women in the Missionvale area

  • Authors: Du Preez, Mingon
  • Date: 2020
  • Subjects: Pregnant women -- Alcohol use
  • Language: English
  • Type: Thesis , Masters , MA
  • Identifier: http://hdl.handle.net/10948/46404 , vital:39572
  • Description: South African statistics, when compared to global statistics, has an above-average occurrence of Fetal Alcohol Spectrum Disorder(FASD). Alcohol use during pregnancy is on the rise globally and has far-reaching consequences. FASD is an umbrella term that describes the range of effects that can occur in an individual whose mother consumed alcohol during pregnancy.FASDnot only has an abiological, social and emotional negative impact on the individual, but also creates an added burden on the family caring for such an individual. When this condition occurs in a third world country, like South Africa, there is an economic impact as this country has limited physical and human resources to deal with the multitude of repercussions associated with this condition. This study was conducted in the Missionvale Community, an impoverished area of Port Elizabeth in the Eastern Cape. Participants were selected from this community, as clients attending the psychology clinic in the area frequently present with diagnosed FASD and co-concurring conditions, such as scholastic underachievement and behavioural conditions. These factors perpetuate an individuals inability to rise above their current circumstances as they are frequently unable to complete their schooling and are consequently unable to find unemployment. Prevention of FASD is a social, public and personal health issue that requires a multifaceted approach to intervention. The present study aimed to determine participants’ awareness, knowledge levels and practices with regard to alcohol use during pregnancy. Previous studies conducted in the Eastern Cape have primarily focused on the outcomes of prenatal alcohol exposure rather than the contributing factors, thus making this study the first of its kind to be conducted in the Eastern Cape. The study was quantitative in nature and participants were obtained through purposive sampling. A questionnaire, comprising of four different sections was used to obtain the necessary information. The sections in the questionnaire tapped information about the following concepts: Demographics, awareness, knowledge, and practices of alcohol use by pregnant women. The statistical results and additional comments by the participants assisted the researcher to gain a better understanding of the awareness levels, knowledge, and practices with regard to alcohol use of pregnant women residing in the Missionvale area. The results from the study indicate that participants have a general awareness that alcohol use during pregnancy could be harmful to an unborn baby but lack in-depth specific knowledge of the adverse effects of prenatal alcohol exposure.
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  • Date Issued: 2020

Azadipyrromethenes for applications in photodynamic antimicrobial chemotherapy, photodynamic therapy and optical limiting

  • Authors: Dubazana, Nadine
  • Date: 2020
  • Subjects: Dyes and dyeing -- Chemistry , Photochemotherapy , Cancer -- Photochemotherapy , Anti-infective agents , Staphylococcus aureus , Nonlinear optics , Azadipyrromethenes , BODIPY
  • Language: English
  • Type: text , Thesis , Masters , MSc
  • Identifier: http://hdl.handle.net/10962/166150 , vital:41333
  • Description: Azadipyrromethenes, azaBODIPYs and zinc azadipyrromethene complexes were prepared and characterised to examine the effect on their photophysical properties of incorporating phenyl groups at the 1,3,5,7-positions with electron-donating and withdrawing groups at the para-positions. To enhance their ability to generate singlet oxygen, appropriate structural modifications were made through the addition of a Zn(II) ion or halogenation at the 2,6 positions. In vitro photodynamic therapy (PDT) studies targeting MCF-7 human breast cancer cells were carried out. To evaluate and understand the effectiveness of the dyes as photosensitisers, cellular uptake, phototoxicity and the half-maximal inhibitory concentration (IC50) values were analysed. Photodynamic antimicrobial chemotherapy (PACT) studies were also carried out to study the effectiveness of the dyes against Staphylococcus aureus (S. aureus). Dyes with donor-π-acceptor (D-π-A) properties were synthesised and tested against the second harmonic of the Nd:YAG laser in optical limiting (OL) studies. The second-order hyperpolarisability, third-order susceptibility and nonlinear absorption coefficient values were determined. The results suggest that 1,3,5,7-azaBODIPY dyes may be less suitable for use in this context than analogous D-π-A 3,5-distyrylBODIPY dyes. Molecular modelling was carried out to identify the structure-property relationships of the synthesised dyes by analysing trends in the energies of the frontier molecular orbitals (MOs) and spectroscopic properties.
  • Full Text:
  • Date Issued: 2020

Bacterial degradation of coal discard and geologically weathered coal:

  • Authors: Olawale, Jacob T , Edeki, Oghenekume G , Cowan, Keith A
  • Date: 2020
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/178694 , vital:40097 , https://doi.org/10.1007/s40789-020-00306-3
  • Description: The biodegradation of coal discard is being intensively studied in South Africa in an effort to develop passive methods for the successful revegetation and rehabilitation of waste dumps, to mitigate pollution, and facilitate mine closure. Bacteria were isolated from slurries of coal tailings and diesel-contaminated soil, screened for coal biodegradation competence, characterized, and the colonization and degradation of coal discard and geologically weathered coal investigated using individual isolates and consortia. Ten novel coal-degrading bacterial strains were isolated and characterized, the gene sequences deposited with GenBank, and the (wild-type) strains deposited at Microbial Culture Collection, India.
  • Full Text:
  • Date Issued: 2020
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