The Malarial Exported PFA0660w Is an Hsp40 Co-Chaperone of PfHsp70-x
- Daniyan, Michael O, Boshoff, Aileen, Prinsloo, Earl, Pesce, Eva-Rachele, Blatch, Gregory L
- Authors: Daniyan, Michael O , Boshoff, Aileen , Prinsloo, Earl , Pesce, Eva-Rachele , Blatch, Gregory L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66098 , vital:28901 , https://doi.org/10.1371/journal.pone.0148517
- Description: publisher version , Plasmodium falciparum, the human pathogen responsible for the most dangerous malaria infection, survives and develops in mature erythrocytes through the export of proteins needed for remodelling of the host cell. Molecular chaperones of the heat shock protein (Hsp) family are prominent members of the exportome, including a number of Hsp40s and a Hsp70. PFA0660w, a type II Hsp40, has been shown to be exported and possibly form a complex with PfHsp70-x in the infected erythrocyte cytosol. However, the chaperone properties of PFA0660w and its interaction with human and parasite Hsp70s are yet to be investigated. Recombinant PFA0660w was found to exist as a monomer in solution, and was able to significantly stimulate the ATPase activity of PfHsp70-x but not that of a second plasmodial Hsp70 (PfHsp70-1) or a human Hsp70 (HSPA1A), indicating a potential specific functional partnership with PfHsp70-x. Protein binding studies in the presence and absence of ATP suggested that the interaction of PFA0660w with PfHsp70-x most likely represented a co-chaperone/chaperone interaction. Also, PFA0660w alone produced a concentration-dependent suppression of rhodanese aggregation, demonstrating its chaperone properties. Overall, we have provided the first biochemical evidence for the possible role of PFA0660w as a chaperone and as co-chaperone of PfHsp70-x. We propose that these chaperones boost the chaperone power of the infected erythrocyte, enabling successful protein trafficking and folding, and thereby making a fundamental contribution to the pathology of malaria. , This work was supported by grants from the National Research Foundation (NRF) and Medical Research Council (MRC) of South Africa. The ProteOn XPR36 IAS was purchased from a National Nanotechnology Equipment Programme grant from the Department of Science and Technology and the NRF of South Africa. Michael O. Daniyan was a recipient of the Education Trust Fund (ETF) Academic Staff Training and Development (AST and D) scholarship of Obafemi Awolowo University, Ile-Ife, Nigeria and a Rhodes University Council research bursary
- Full Text:
- Date Issued: 2016
- Authors: Daniyan, Michael O , Boshoff, Aileen , Prinsloo, Earl , Pesce, Eva-Rachele , Blatch, Gregory L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66098 , vital:28901 , https://doi.org/10.1371/journal.pone.0148517
- Description: publisher version , Plasmodium falciparum, the human pathogen responsible for the most dangerous malaria infection, survives and develops in mature erythrocytes through the export of proteins needed for remodelling of the host cell. Molecular chaperones of the heat shock protein (Hsp) family are prominent members of the exportome, including a number of Hsp40s and a Hsp70. PFA0660w, a type II Hsp40, has been shown to be exported and possibly form a complex with PfHsp70-x in the infected erythrocyte cytosol. However, the chaperone properties of PFA0660w and its interaction with human and parasite Hsp70s are yet to be investigated. Recombinant PFA0660w was found to exist as a monomer in solution, and was able to significantly stimulate the ATPase activity of PfHsp70-x but not that of a second plasmodial Hsp70 (PfHsp70-1) or a human Hsp70 (HSPA1A), indicating a potential specific functional partnership with PfHsp70-x. Protein binding studies in the presence and absence of ATP suggested that the interaction of PFA0660w with PfHsp70-x most likely represented a co-chaperone/chaperone interaction. Also, PFA0660w alone produced a concentration-dependent suppression of rhodanese aggregation, demonstrating its chaperone properties. Overall, we have provided the first biochemical evidence for the possible role of PFA0660w as a chaperone and as co-chaperone of PfHsp70-x. We propose that these chaperones boost the chaperone power of the infected erythrocyte, enabling successful protein trafficking and folding, and thereby making a fundamental contribution to the pathology of malaria. , This work was supported by grants from the National Research Foundation (NRF) and Medical Research Council (MRC) of South Africa. The ProteOn XPR36 IAS was purchased from a National Nanotechnology Equipment Programme grant from the Department of Science and Technology and the NRF of South Africa. Michael O. Daniyan was a recipient of the Education Trust Fund (ETF) Academic Staff Training and Development (AST and D) scholarship of Obafemi Awolowo University, Ile-Ife, Nigeria and a Rhodes University Council research bursary
- Full Text:
- Date Issued: 2016
The management of chacma baboons and humans in a peri-urban environment: a case study from Nelson Mandela Metropolitan University's George Campus
- Authors: Botes, Peet
- Date: 2016
- Subjects: Human-animal relationships , Animal behavior , Human beings , Bestiality
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/5135 , vital:20812
- Description: Conflicts between humans and baboons (Papio ursinus) have become a significant management challenge on Nelson Mandela Metropolitan University’s (NMMUs) George Campus, which is located in peri-urban George in the Garden Route, of the Western Cape of South Africa. Current management policy, although required to be ‘scientifically’ based, largely relies on studies done outside the Garden Route. This study addresses the question of how the management of human-baboon relations could be improved on the campus. A case study was undertaken which aimed at addressing the cohabitation of baboons and humans on the NMMU campus, specifically human-baboon resource selection and interaction. The research methodology and the related analytical tools were primarily quantitative but were supplemented by some qualitative data drawn from interviews. Data collected was used to determine landscape features acting as Keystone Resource Areas (KRAs) for both humans and baboons on the campus. Relationships between the frequency and location of negative interactions, and resident-baboon distribution on the campus were also determined. Two key findings emerged from the research. First, residences, non-residence buildings and waste disposal stations act as KRAs for both humans and baboons. Second, the frequency of negative interaction correlates with the time spent by residents and baboons at residences, where common negative interactions between baboons and humans are known to occur. It is postulated that cohabitation on the NMMU George Campus is causing the habituation of baboons, a loss of fear of humans and association of humans with high energy foods. As a result, present cohabitation contributes to negative human-baboon relations in the George area. To ensure sustainable co-existence between humans and baboons on the George Campus, management should implement zonation and wildlife monitoring to reverse the loss of baboon fear of humans and better limit the availability of human-derived foods. In addition, management should consider giving stakeholders co-management roles to foster and facilitate knowledge and responsibility partnerships, and subsequently correct any misunderstandings related to human-baboon relations on the campus. Recommendations for further research include sampling beyond campus boundaries to compensate for regional variations in baboon behaviour and the biophysical environment.
- Full Text:
- Date Issued: 2016
- Authors: Botes, Peet
- Date: 2016
- Subjects: Human-animal relationships , Animal behavior , Human beings , Bestiality
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/5135 , vital:20812
- Description: Conflicts between humans and baboons (Papio ursinus) have become a significant management challenge on Nelson Mandela Metropolitan University’s (NMMUs) George Campus, which is located in peri-urban George in the Garden Route, of the Western Cape of South Africa. Current management policy, although required to be ‘scientifically’ based, largely relies on studies done outside the Garden Route. This study addresses the question of how the management of human-baboon relations could be improved on the campus. A case study was undertaken which aimed at addressing the cohabitation of baboons and humans on the NMMU campus, specifically human-baboon resource selection and interaction. The research methodology and the related analytical tools were primarily quantitative but were supplemented by some qualitative data drawn from interviews. Data collected was used to determine landscape features acting as Keystone Resource Areas (KRAs) for both humans and baboons on the campus. Relationships between the frequency and location of negative interactions, and resident-baboon distribution on the campus were also determined. Two key findings emerged from the research. First, residences, non-residence buildings and waste disposal stations act as KRAs for both humans and baboons. Second, the frequency of negative interaction correlates with the time spent by residents and baboons at residences, where common negative interactions between baboons and humans are known to occur. It is postulated that cohabitation on the NMMU George Campus is causing the habituation of baboons, a loss of fear of humans and association of humans with high energy foods. As a result, present cohabitation contributes to negative human-baboon relations in the George area. To ensure sustainable co-existence between humans and baboons on the George Campus, management should implement zonation and wildlife monitoring to reverse the loss of baboon fear of humans and better limit the availability of human-derived foods. In addition, management should consider giving stakeholders co-management roles to foster and facilitate knowledge and responsibility partnerships, and subsequently correct any misunderstandings related to human-baboon relations on the campus. Recommendations for further research include sampling beyond campus boundaries to compensate for regional variations in baboon behaviour and the biophysical environment.
- Full Text:
- Date Issued: 2016
The managerial leadership styles of school principals for school effectiveness: a study of six Secondary schools of the Dutywa Education District
- Authors: Ziduli, Mlungiseleli
- Date: 2016
- Subjects: High school -- Management Secondary education performance -- School leadership
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: http://hdl.handle.net/11260/504 , vital:27279
- Description: The purpose of this study was to investigate the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District in the Eastern Cape Province of the Republic of South. The literature review reflects theories concerning the managerial leadership styles of school principals for school effectiveness. In order to attain the aims and objectives of the study, the researcher used the qualitative research method, both in collecting and analyzing the data. The case study design was used to describe and access the phenomenon and the purposive sampling method was used to select (6) secondary school principals. An open ended interview schedule was used for the face-to-face in-depth interviews on the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District. Themes were drawn from the responses of the participants and analysed. Some of the findings were: Democratic and participatory leadership styles were used by the school principals to achieve maximum co-operation from both experienced and beginning teachers and the learners in the schools. Laissez fair and autocratic styles of leadership appeared to be undesirable for the management of schools. For school principals’ effective management, they need to do proper planning, organising and scheduling of activities, assigning duties to teachers and delegating some of their work to competent teachers. The reasons for school principals’ ineffectiveness in this study were: favouritism, over-familiar relationships with some teachers, ignoring teachers’ personal problems, workload, lack of support and co-operation from teachers. Incorrect interpretation of educational policies were seen to lead to chaotic situations, poor performance of both teachers and learners, division between learners and teachers, a lack of unity between school stake-holders, poor job satisfaction and lack of trust and respect for the principals concerned. Factors contributing to principals’ incorrect interpretation of educational policies and execution of management roles were: negligence, lack of knowledge and ability to interpret educational policies, lack of proper induction programmes and training of principals and lack of support on policy matters from the Department of Education. Contributing factors resulting in barriers to principals’ ineffectiveness in the management of schools were: failure to give proper instructions to teachers and learners, failure to effectively use of available funds in the school, failure to implement all educational programmes in the school including co-curricular and extra mural activities, lack of experience, lack of support from both the Department of Education and the parents, lack of resources, high staff turnover, favourtisms and failure to hold teachers accountable for poor work done. Mechanisms deemed to overcome the factors leading to barriers to principals’ execution of their management roles at schools were: making the effort to be knowledgeable about educational policies, timely responses to problems in the school, regular consultation with stakeholders, employment of SGB teachers, taking direct supervision of instructions in classrooms and endeavoring to have good relations and gaining support from the SGB and the parents. The researcher made some recommendations on the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District.
- Full Text:
- Date Issued: 2016
- Authors: Ziduli, Mlungiseleli
- Date: 2016
- Subjects: High school -- Management Secondary education performance -- School leadership
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: http://hdl.handle.net/11260/504 , vital:27279
- Description: The purpose of this study was to investigate the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District in the Eastern Cape Province of the Republic of South. The literature review reflects theories concerning the managerial leadership styles of school principals for school effectiveness. In order to attain the aims and objectives of the study, the researcher used the qualitative research method, both in collecting and analyzing the data. The case study design was used to describe and access the phenomenon and the purposive sampling method was used to select (6) secondary school principals. An open ended interview schedule was used for the face-to-face in-depth interviews on the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District. Themes were drawn from the responses of the participants and analysed. Some of the findings were: Democratic and participatory leadership styles were used by the school principals to achieve maximum co-operation from both experienced and beginning teachers and the learners in the schools. Laissez fair and autocratic styles of leadership appeared to be undesirable for the management of schools. For school principals’ effective management, they need to do proper planning, organising and scheduling of activities, assigning duties to teachers and delegating some of their work to competent teachers. The reasons for school principals’ ineffectiveness in this study were: favouritism, over-familiar relationships with some teachers, ignoring teachers’ personal problems, workload, lack of support and co-operation from teachers. Incorrect interpretation of educational policies were seen to lead to chaotic situations, poor performance of both teachers and learners, division between learners and teachers, a lack of unity between school stake-holders, poor job satisfaction and lack of trust and respect for the principals concerned. Factors contributing to principals’ incorrect interpretation of educational policies and execution of management roles were: negligence, lack of knowledge and ability to interpret educational policies, lack of proper induction programmes and training of principals and lack of support on policy matters from the Department of Education. Contributing factors resulting in barriers to principals’ ineffectiveness in the management of schools were: failure to give proper instructions to teachers and learners, failure to effectively use of available funds in the school, failure to implement all educational programmes in the school including co-curricular and extra mural activities, lack of experience, lack of support from both the Department of Education and the parents, lack of resources, high staff turnover, favourtisms and failure to hold teachers accountable for poor work done. Mechanisms deemed to overcome the factors leading to barriers to principals’ execution of their management roles at schools were: making the effort to be knowledgeable about educational policies, timely responses to problems in the school, regular consultation with stakeholders, employment of SGB teachers, taking direct supervision of instructions in classrooms and endeavoring to have good relations and gaining support from the SGB and the parents. The researcher made some recommendations on the managerial leadership styles of school principals for school effectiveness at secondary schools of the Dutywa Education District.
- Full Text:
- Date Issued: 2016
The maturity of project management in engineering consulting firms
- Authors: Machite, Kennedy
- Date: 2016
- Subjects: Project management Consulting engineers -- South Africa , Engineering firms -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/18409 , vital:28634
- Description: With a considerable number of built environment projects not being completed successfully, this study was undertaken to investigate how effectively consulting engineering firms are applying project management principles in the way they manage projects. This was achieved by measuring the project management maturity levels of consulting engineering firms. Maturity levels were measured for each of the ten knowledge areas of the Project Management Institute’s Project Management Body of Knowledge to determine areas where consulting engineering firms perform below expectation and as a result determine probable causes of project failures. The maturity of the firm was then calculated as the average of the maturity for the knowledge areas. The study found that consulting engineering firms have higher levels of project management maturity than the average for the construction and civil engineering sector. Apart from risk and procurement management, all the other knowledge areas have higher maturity levels than the corresponding construction and civil engineering knowledge areas. Although the overall maturity results indicate that the larger firms are more mature in their project management practices than the smaller firms, the individual knowledge areas are inconsistent. The study reveals that consulting engineering firms are weakest in the risk management, human resources and stakeholder management knowledge areas. There is limited literature available on the status of project management, project management methodologies, and performance of consulting projects in the engineering environment (Labuschagne & Steyn, 2010:70). There is need for future studies to establish a methodology developed specifically for the Consulting Engineering Firms in line with what Labuschagne & Steyn (2010) started and a Project Management Maturity Model specific to the Consulting Engineering Industry.
- Full Text:
- Date Issued: 2016
- Authors: Machite, Kennedy
- Date: 2016
- Subjects: Project management Consulting engineers -- South Africa , Engineering firms -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/18409 , vital:28634
- Description: With a considerable number of built environment projects not being completed successfully, this study was undertaken to investigate how effectively consulting engineering firms are applying project management principles in the way they manage projects. This was achieved by measuring the project management maturity levels of consulting engineering firms. Maturity levels were measured for each of the ten knowledge areas of the Project Management Institute’s Project Management Body of Knowledge to determine areas where consulting engineering firms perform below expectation and as a result determine probable causes of project failures. The maturity of the firm was then calculated as the average of the maturity for the knowledge areas. The study found that consulting engineering firms have higher levels of project management maturity than the average for the construction and civil engineering sector. Apart from risk and procurement management, all the other knowledge areas have higher maturity levels than the corresponding construction and civil engineering knowledge areas. Although the overall maturity results indicate that the larger firms are more mature in their project management practices than the smaller firms, the individual knowledge areas are inconsistent. The study reveals that consulting engineering firms are weakest in the risk management, human resources and stakeholder management knowledge areas. There is limited literature available on the status of project management, project management methodologies, and performance of consulting projects in the engineering environment (Labuschagne & Steyn, 2010:70). There is need for future studies to establish a methodology developed specifically for the Consulting Engineering Firms in line with what Labuschagne & Steyn (2010) started and a Project Management Maturity Model specific to the Consulting Engineering Industry.
- Full Text:
- Date Issued: 2016
The mediating processes within social learning: women’s food and water security practices in the rural Eastern Cape
- Authors: Rivers, Nina
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/888 , vital:20000
- Description: The focus of this study was to explore the implicit and explicit mediating processes within the social learning of women’s food and water security practices in the rural Eastern Cape, South Africa. The study was undertaken in response to a growing problem of learning resources being decontextualised and therefore being of little relevance or use to the everyday practices of the people they were developed for. The central thesis of this study is that if the mediating processes that shape practice and learning are understood then these practices and learning can be better supported. One of the main foci of this study therefore is the concept of mediation and the importance of understanding the implicit and explicit mediating processes that shape learning and practice within the context of rainwater harvesting and food gardening practices of rural women. The study interprets these as social learning processes after the work of Lev Vygotsky and post-Vygotskian learning and activity development research, which recognises that all learning is socially mediated. This study also attempts to show that ontological factors also shape social learning processes via structural mediations (which are often also socially structured over time in history). Working within the broad framework of change oriented social learning, education for sustainability and the southern African water and food nexus the study is focused around two central research questions: 1) What are the mediating processes evident in and surrounding the learning of rainwater harvesting in the context of women’s water and food security in rural communities? And 2) How can a question-based learning resource extend the learning practices in this context? Drawing on three sensitising concepts of dialectics, reflexivity and agency, the study worked with Cultural Historical Activity Theory (CHAT), underpinned by critical realism, to reveal how the learning of rainwater and food gardening practitioners is constrained and enabled by mediating processes. The theory of mediation provided a useful theoretical lens with which to examine data generated. A case study approach was used in two sites in the rural Eastern Cape. The first was Cata village in the Amathole district and the second was a peri-urban settlement called Glenconnor in the Cacadu district. Each case study is constituted within a networked activity system. The study also used a narrative inquiry approach in order to bring to life the case studies, activity systems and some of the dynamics of social learning within the study. The methodological tools of document analysis, observations, in-depth interviews and focus group discussions were used to explore the implicit and explicit mediating processes that shape research participants’ rainwater harvesting and food gardening practices and their learning. Inductive, abductive and retroductive modes of inference were used to analyse data in and across case studies. One of the first findings of this study is that learning is embedded in and emergent from context in that it is mediated by implicit and explicit processes within each context. This makes such learning social, in the sense of social used by Vygotsky. The second finding showed that implicit and explicit mediation processes are constantly interacting in a dialectical process whether people are conscious of this interplay or not. This is an important dynamic to understand when trying to bring about societal transformation through education. Understanding the interaction between the implicit and explicit alerts researchers to the sociocultural dynamics inherent within social learning processes and therefore informs how learning resources and educational and development programmes should be designed and implemented. This study contributes to new knowledge in the environmental education field and the water knowledge sector. It makes a theoretical and empirical contribution to the body of knowledge concerned with socially mediated learning and situated learning approaches. The study illustrates how learning is embedded in context and also how learning emerges in relation to context via interactions between implicit and explicit mediation processes, and considers what this means for learning and development in the rural nexus of water and food security practices. This study also contributes to the growing body of post-Vygotskian social learning research in southern Africa that is being developed in the context of cultural historical activity theory as it shows the dialectical relationship that exists between implicit and explicit forms of mediation as these are embedded in, emergent from, and are externally mediated into activity systems in rural community contexts. This study contributes to a second area of knowledge: the water sector. With a background in anthropology which sensitised the researcher to contextual factors and approaching the study through an educational lens, the data has been worked with to surface and present the nuanced mediating processes that shape the learning and knowledge around water issues. This way of working and this focus on the socio-cultural is relatively new in the water sector in South Africa and gains significance in the light of an emergent interest in more complex social studies in the water sector which has traditionally been dominated by natural sciences and engineering. The significance of this study for rural South African women’s lives is that by understanding and taking account of their history, context, struggles and experiences, their learning and practices can be better supported through more relevant learning resources and programmes.
- Full Text:
- Date Issued: 2016
- Authors: Rivers, Nina
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/888 , vital:20000
- Description: The focus of this study was to explore the implicit and explicit mediating processes within the social learning of women’s food and water security practices in the rural Eastern Cape, South Africa. The study was undertaken in response to a growing problem of learning resources being decontextualised and therefore being of little relevance or use to the everyday practices of the people they were developed for. The central thesis of this study is that if the mediating processes that shape practice and learning are understood then these practices and learning can be better supported. One of the main foci of this study therefore is the concept of mediation and the importance of understanding the implicit and explicit mediating processes that shape learning and practice within the context of rainwater harvesting and food gardening practices of rural women. The study interprets these as social learning processes after the work of Lev Vygotsky and post-Vygotskian learning and activity development research, which recognises that all learning is socially mediated. This study also attempts to show that ontological factors also shape social learning processes via structural mediations (which are often also socially structured over time in history). Working within the broad framework of change oriented social learning, education for sustainability and the southern African water and food nexus the study is focused around two central research questions: 1) What are the mediating processes evident in and surrounding the learning of rainwater harvesting in the context of women’s water and food security in rural communities? And 2) How can a question-based learning resource extend the learning practices in this context? Drawing on three sensitising concepts of dialectics, reflexivity and agency, the study worked with Cultural Historical Activity Theory (CHAT), underpinned by critical realism, to reveal how the learning of rainwater and food gardening practitioners is constrained and enabled by mediating processes. The theory of mediation provided a useful theoretical lens with which to examine data generated. A case study approach was used in two sites in the rural Eastern Cape. The first was Cata village in the Amathole district and the second was a peri-urban settlement called Glenconnor in the Cacadu district. Each case study is constituted within a networked activity system. The study also used a narrative inquiry approach in order to bring to life the case studies, activity systems and some of the dynamics of social learning within the study. The methodological tools of document analysis, observations, in-depth interviews and focus group discussions were used to explore the implicit and explicit mediating processes that shape research participants’ rainwater harvesting and food gardening practices and their learning. Inductive, abductive and retroductive modes of inference were used to analyse data in and across case studies. One of the first findings of this study is that learning is embedded in and emergent from context in that it is mediated by implicit and explicit processes within each context. This makes such learning social, in the sense of social used by Vygotsky. The second finding showed that implicit and explicit mediation processes are constantly interacting in a dialectical process whether people are conscious of this interplay or not. This is an important dynamic to understand when trying to bring about societal transformation through education. Understanding the interaction between the implicit and explicit alerts researchers to the sociocultural dynamics inherent within social learning processes and therefore informs how learning resources and educational and development programmes should be designed and implemented. This study contributes to new knowledge in the environmental education field and the water knowledge sector. It makes a theoretical and empirical contribution to the body of knowledge concerned with socially mediated learning and situated learning approaches. The study illustrates how learning is embedded in context and also how learning emerges in relation to context via interactions between implicit and explicit mediation processes, and considers what this means for learning and development in the rural nexus of water and food security practices. This study also contributes to the growing body of post-Vygotskian social learning research in southern Africa that is being developed in the context of cultural historical activity theory as it shows the dialectical relationship that exists between implicit and explicit forms of mediation as these are embedded in, emergent from, and are externally mediated into activity systems in rural community contexts. This study contributes to a second area of knowledge: the water sector. With a background in anthropology which sensitised the researcher to contextual factors and approaching the study through an educational lens, the data has been worked with to surface and present the nuanced mediating processes that shape the learning and knowledge around water issues. This way of working and this focus on the socio-cultural is relatively new in the water sector in South Africa and gains significance in the light of an emergent interest in more complex social studies in the water sector which has traditionally been dominated by natural sciences and engineering. The significance of this study for rural South African women’s lives is that by understanding and taking account of their history, context, struggles and experiences, their learning and practices can be better supported through more relevant learning resources and programmes.
- Full Text:
- Date Issued: 2016
The National School Nutrition Programme in selected schools in Peddie
- Authors: Zazini, Thando William
- Date: 2016
- Subjects: School children -- Food -- South Africa -- Peddie School children -- Nutrition , School management teams -- Nutrition -- South Africa -- Peddie
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/12769 , vital:27119
- Description: The Department of Basic Education classifies the NSNP as one of the critical omponents of the government's Programme of Action, which was specifically assigned the responsibility of addressing learners' ability to learn by providing them with nutritious meals. The success of the programme may therefore contribute towards the country's realisation of the Millennium Development Goals which include the reduction of mortality and the eradication of extreme hunger and poverty by 2015 as well as achieving universal primary education. The aim of the National School Nutrition Programme seeks to promote sustainable food production initiatives in all School Nutrition Schools in order to develop skills. It also aims to enhance learning capacity of a learner through feeding and to promote nutrition education in order to improve healthy eating and lifestyles amongst communities. This study seeks to assess the current status in administering the NSNP in selected schools in Peddie, Eastern Cape. Due to the extensive nature of the geographical area of Peddie, this study focused exclusively on 25 schools. For the purpose of this study, a quantitative approach was employed through a questionnaire constructed to obtain the perceptions of the sample group. The responses from the statements in the questionnaire were analysed by a Nelson Mandela Metropolitan University registered statistician. In the last chapter a number of recommendations are stated to aid in improving the current administering status of the National School Nutrition Programme.
- Full Text:
- Date Issued: 2016
- Authors: Zazini, Thando William
- Date: 2016
- Subjects: School children -- Food -- South Africa -- Peddie School children -- Nutrition , School management teams -- Nutrition -- South Africa -- Peddie
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/12769 , vital:27119
- Description: The Department of Basic Education classifies the NSNP as one of the critical omponents of the government's Programme of Action, which was specifically assigned the responsibility of addressing learners' ability to learn by providing them with nutritious meals. The success of the programme may therefore contribute towards the country's realisation of the Millennium Development Goals which include the reduction of mortality and the eradication of extreme hunger and poverty by 2015 as well as achieving universal primary education. The aim of the National School Nutrition Programme seeks to promote sustainable food production initiatives in all School Nutrition Schools in order to develop skills. It also aims to enhance learning capacity of a learner through feeding and to promote nutrition education in order to improve healthy eating and lifestyles amongst communities. This study seeks to assess the current status in administering the NSNP in selected schools in Peddie, Eastern Cape. Due to the extensive nature of the geographical area of Peddie, this study focused exclusively on 25 schools. For the purpose of this study, a quantitative approach was employed through a questionnaire constructed to obtain the perceptions of the sample group. The responses from the statements in the questionnaire were analysed by a Nelson Mandela Metropolitan University registered statistician. In the last chapter a number of recommendations are stated to aid in improving the current administering status of the National School Nutrition Programme.
- Full Text:
- Date Issued: 2016
The need for conflict management in organisations (a health insurance company, Port Elizabeth)
- Authors: Ajam, Razaana
- Date: 2016
- Subjects: Conflict management , Organizational change -- South Africa -- Eastern Cape , Organizational behavior -- South Africa -- Eastern Cape , Interpersonal relations
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/3852 , vital:20469
- Description: Conflict is evident in many spheres of life, however this study concentrated more specifically on conflict relating to organisations. Organisational conflict is seen “as any social collectivity, organisations such as private sector companies, government departments, schools and universities, non-governmental organisations, and political parties all experience internal conflict in varying degrees” (Bradshaw, 2008: 22). Each individual coming into a workplace has created his or her own set of challenges especially in the brutal arena of business. Conflict has destructive and productive qualities that can diminish or elevate processes within an organization (Stone, 1999). If it is not harnessed properly or dealt with in the correct manner, it can damage the reputation of a business; resulting in its downfall and this in turn contaminates and affects peripheral businesses associated with the organisation downstream. This study explored the following key aspects: Background of organisational conflict and its management; Background of the organization; Whether these two areas mentioned above can work together to create a cost effective and efficient outcome when dealing with conflict. The research adopted a mixed method approach with predominant focus on qualitative research methodology. The main focus of this study was conflict management within organisations and to probe and determine whether companies see the need to employ the field of conflict management as a strategy in times of fluctuating dispositions. It is evident that the organisation may not be fully aware or make use of alternative conflict resolution strategies and that the main causes of conflict can be eliminated such as poor communication, ill-defined job descriptions and objectives and differing of opinions. The need to employ alternative methods of conflict management may be emphasised by looking at the costs that conflict produces and the use of limited vital resources and the loss of human capital.
- Full Text:
- Date Issued: 2016
- Authors: Ajam, Razaana
- Date: 2016
- Subjects: Conflict management , Organizational change -- South Africa -- Eastern Cape , Organizational behavior -- South Africa -- Eastern Cape , Interpersonal relations
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/3852 , vital:20469
- Description: Conflict is evident in many spheres of life, however this study concentrated more specifically on conflict relating to organisations. Organisational conflict is seen “as any social collectivity, organisations such as private sector companies, government departments, schools and universities, non-governmental organisations, and political parties all experience internal conflict in varying degrees” (Bradshaw, 2008: 22). Each individual coming into a workplace has created his or her own set of challenges especially in the brutal arena of business. Conflict has destructive and productive qualities that can diminish or elevate processes within an organization (Stone, 1999). If it is not harnessed properly or dealt with in the correct manner, it can damage the reputation of a business; resulting in its downfall and this in turn contaminates and affects peripheral businesses associated with the organisation downstream. This study explored the following key aspects: Background of organisational conflict and its management; Background of the organization; Whether these two areas mentioned above can work together to create a cost effective and efficient outcome when dealing with conflict. The research adopted a mixed method approach with predominant focus on qualitative research methodology. The main focus of this study was conflict management within organisations and to probe and determine whether companies see the need to employ the field of conflict management as a strategy in times of fluctuating dispositions. It is evident that the organisation may not be fully aware or make use of alternative conflict resolution strategies and that the main causes of conflict can be eliminated such as poor communication, ill-defined job descriptions and objectives and differing of opinions. The need to employ alternative methods of conflict management may be emphasised by looking at the costs that conflict produces and the use of limited vital resources and the loss of human capital.
- Full Text:
- Date Issued: 2016
The network society: A model for computing infrastructure in South African schools
- Siebörger, Ingrid, Terzoli, Alfredo
- Authors: Siebörger, Ingrid , Terzoli, Alfredo
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430651 , vital:72706 , 10.1109/ISTAFRICA.2016.7530673
- Description: Worldwide computers are being used in schools for, amongst other things, developing the knowledge and skills required for citizens to be able to operate within the 21st Century Information Age. Realising the potential of technology in uplifting the lives of its citizens the South Afri-can government has proposed the National Broadband Plan (SA Con-nect). However, unfortunately this plan only addresses the networking aspect of Information Communication Technologies (ICTs). In this pa-per we investigate appropriate Information Technologies for schools in the light of SA Connect, and propose a model for the computing infra-structure required in South African schools in order to support access to and adoption of technology and networks. This model is based on our multi-year experimentation in the Siyakhula Living Lab.
- Full Text:
- Date Issued: 2016
- Authors: Siebörger, Ingrid , Terzoli, Alfredo
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430651 , vital:72706 , 10.1109/ISTAFRICA.2016.7530673
- Description: Worldwide computers are being used in schools for, amongst other things, developing the knowledge and skills required for citizens to be able to operate within the 21st Century Information Age. Realising the potential of technology in uplifting the lives of its citizens the South Afri-can government has proposed the National Broadband Plan (SA Con-nect). However, unfortunately this plan only addresses the networking aspect of Information Communication Technologies (ICTs). In this pa-per we investigate appropriate Information Technologies for schools in the light of SA Connect, and propose a model for the computing infra-structure required in South African schools in order to support access to and adoption of technology and networks. This model is based on our multi-year experimentation in the Siyakhula Living Lab.
- Full Text:
- Date Issued: 2016
The optical limiting of blue and green ytterbium double-decker phthalocyanines in solution and in poly (acrylic acid) as thin films
- Sekhosana, Kutloana E, Nyokong, Tebello
- Authors: Sekhosana, Kutloana E , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188585 , vital:44767 , xlink:href="https://doi.org/10.1016/j.ica.2016.05.026"
- Description: Bis{1(4), 8(11), 15(18), 22(25)-tetra(4-tert-butylphenoxy)phthalocyaninato} ytterbium(III) (2a) (the green form) was synthesized and reduced to form 2b (the blue form). Nonlinear optical parameters for complex 2 in green and blue forms were determined using the Z-scan technique and the values of third-order imaginary susceptibility (Im[χ(3)]) and second-order hyperpolarizability (γ) of the order of 10−9 (for 2b) and 10−27 esu, respectively, were obtained in solution. In poly(acrylic acid) as a thin film, complex 2a showed extremely high Im[χ(3)] and γ values of the order 10−8 and 10−25 respectively. A low optical limiting threshold value of 0.075 J cm−2 was obtained for the thin film 2a.
- Full Text:
- Date Issued: 2016
- Authors: Sekhosana, Kutloana E , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188585 , vital:44767 , xlink:href="https://doi.org/10.1016/j.ica.2016.05.026"
- Description: Bis{1(4), 8(11), 15(18), 22(25)-tetra(4-tert-butylphenoxy)phthalocyaninato} ytterbium(III) (2a) (the green form) was synthesized and reduced to form 2b (the blue form). Nonlinear optical parameters for complex 2 in green and blue forms were determined using the Z-scan technique and the values of third-order imaginary susceptibility (Im[χ(3)]) and second-order hyperpolarizability (γ) of the order of 10−9 (for 2b) and 10−27 esu, respectively, were obtained in solution. In poly(acrylic acid) as a thin film, complex 2a showed extremely high Im[χ(3)] and γ values of the order 10−8 and 10−25 respectively. A low optical limiting threshold value of 0.075 J cm−2 was obtained for the thin film 2a.
- Full Text:
- Date Issued: 2016
The participatory development and implementation of a facilitator’s manual for the promotion of exclusive breastfeeding
- Authors: Katsinde, Shingirai Miranda
- Date: 2016
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/4201 , vital:20632
- Description: Background: Breastfeeding is a common practice, but exclusive breastfeeding for the first six months is no longer a cultural norm in the majority of South African communities. Identification of facilitating and constraining factors which affect breastfeeding and exclusive breastfeeding practices is thus important. The promotion of exclusive breastfeeding is essential for improved infant health and development, especially if it takes into consideration the broader cultural and socio-economic aspects influencing these practices. This study follows up on an initial project conducted in Glenmore and Ndwayana, two rural communities in the Eastern Cape, South Africa. The current study aimed at working with community care workers who are associated with two community based organisations, who work within three communities, Glenmore, Ndwayana and Grahamstown. The study objectives were to identify the factors that influence the adoption of exclusive breastfeeding in the communities researched, to conduct workshops with the community workers on exclusive breastfeeding practices, as well as to develop and implement a facilitator’s manual for the promotion of exclusive breastfeeding. Method: Using the community based participatory research approach and the PEN-3 theoretical framework to guide the research process, individual semi-structured interviews were conducted with 14 community care workers to identify the factors that affect breastfeeding and exclusive breastfeeding. Through participatory involvement and a cyclical research process, a facilitator’s manual on breastfeeding was developed, which was used during the workshops in the training of community care workers on breastfeeding and exclusive breastfeeding practices. A pre and post intervention knowledge questionnaire was given to the community care workers to complete before and after the workshops. The facilitator’s manual was modified based on 14 months of consistent interaction with the community care workers, who provided feedback on improving the content as well as on how to enhance the cultural appropriateness of the facilitator’s manual during guided focus group discussions. Readability testing also guided further modification of the facilitator’s manual. Results:The major findings confirmed that exclusive breastfeeding for six months was no longer a common practice in these three communities. Factors affecting breastfeeding and exclusive breastfeeding were classified as perceptions (knowledge attitudes and beliefs), enablers (resources and facilities) and nurturers (people), in accordance with the PEN-3 model thematic categories. The knowledge questionnaire, semi-structured interview results, and data from the workshops showed that the community care workers were not sufficiently equipped with information on breastfeeding and exclusive breastfeeding. The facilitator’s manual development and modification was made possible by inputs from the community care workers and the community based organisation liaisons. A culturally appropriate, community specific facilitator’s manual for the promotion of breastfeeding and exclusive breastfeeding was produced. Conclusion: The factors affecting breastfeeding and exclusive breastfeeding were identified. These factors were useful in facilitating discussions on how to improve breastfeeding and exclusive breastfeeding practices in the communities researched. The facilitator’s manual and the workshops were useful in equipping community care workers with knowledge on breastfeeding and exclusive breastfeeding. The involvement of community based organisations will assist to ensure sustainability of breastfeeding promotion by community care workers by adopting the facilitator’s manual as part of their women and child development programmes.
- Full Text:
- Date Issued: 2016
- Authors: Katsinde, Shingirai Miranda
- Date: 2016
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/4201 , vital:20632
- Description: Background: Breastfeeding is a common practice, but exclusive breastfeeding for the first six months is no longer a cultural norm in the majority of South African communities. Identification of facilitating and constraining factors which affect breastfeeding and exclusive breastfeeding practices is thus important. The promotion of exclusive breastfeeding is essential for improved infant health and development, especially if it takes into consideration the broader cultural and socio-economic aspects influencing these practices. This study follows up on an initial project conducted in Glenmore and Ndwayana, two rural communities in the Eastern Cape, South Africa. The current study aimed at working with community care workers who are associated with two community based organisations, who work within three communities, Glenmore, Ndwayana and Grahamstown. The study objectives were to identify the factors that influence the adoption of exclusive breastfeeding in the communities researched, to conduct workshops with the community workers on exclusive breastfeeding practices, as well as to develop and implement a facilitator’s manual for the promotion of exclusive breastfeeding. Method: Using the community based participatory research approach and the PEN-3 theoretical framework to guide the research process, individual semi-structured interviews were conducted with 14 community care workers to identify the factors that affect breastfeeding and exclusive breastfeeding. Through participatory involvement and a cyclical research process, a facilitator’s manual on breastfeeding was developed, which was used during the workshops in the training of community care workers on breastfeeding and exclusive breastfeeding practices. A pre and post intervention knowledge questionnaire was given to the community care workers to complete before and after the workshops. The facilitator’s manual was modified based on 14 months of consistent interaction with the community care workers, who provided feedback on improving the content as well as on how to enhance the cultural appropriateness of the facilitator’s manual during guided focus group discussions. Readability testing also guided further modification of the facilitator’s manual. Results:The major findings confirmed that exclusive breastfeeding for six months was no longer a common practice in these three communities. Factors affecting breastfeeding and exclusive breastfeeding were classified as perceptions (knowledge attitudes and beliefs), enablers (resources and facilities) and nurturers (people), in accordance with the PEN-3 model thematic categories. The knowledge questionnaire, semi-structured interview results, and data from the workshops showed that the community care workers were not sufficiently equipped with information on breastfeeding and exclusive breastfeeding. The facilitator’s manual development and modification was made possible by inputs from the community care workers and the community based organisation liaisons. A culturally appropriate, community specific facilitator’s manual for the promotion of breastfeeding and exclusive breastfeeding was produced. Conclusion: The factors affecting breastfeeding and exclusive breastfeeding were identified. These factors were useful in facilitating discussions on how to improve breastfeeding and exclusive breastfeeding practices in the communities researched. The facilitator’s manual and the workshops were useful in equipping community care workers with knowledge on breastfeeding and exclusive breastfeeding. The involvement of community based organisations will assist to ensure sustainability of breastfeeding promotion by community care workers by adopting the facilitator’s manual as part of their women and child development programmes.
- Full Text:
- Date Issued: 2016
The past in the present: race, gender and transnationalism in Zoë Wicomb’s October and Chimamanda Ngozi Adichie’s Americanah
- Authors: Nthunya, Manosa
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3939 , vital:20559
- Description: This thesis will interrogate the ways in which the most recent novels of Zoë Wicomb and Chimamanda Ngozi Adichie (namely October and Americanah) explore race, gender and transnational issues. Wicomb and Adichie share an interest in representing the lives of people who have been historically marginalised by racial and gender classifications. This thesis will argue that historical and stereotypical ways of looking at people, particularly African people, are still prevalent in the twenty-first century. Wicomb’s interest is in the coloured community and the impact that apartheid ideology has had on it. She shows, as this thesis will argue, that notions of shame and respectability still influence the coloured community, post-1994, in the same ways they did under apartheid. Furthermore, the thesis will show that religion, which was used to justify apartheid, has been instrumental in maintaining racist and sexist norms in the coloured community in post-apartheid South Africa. Adichie’s novel, on the other hand, shows the impact of gender norms in Nigeria on her female characters. Unlike characters in Wicomb’s novel, Adichie’s mostly experience racial bias when they move to Western countries. This thesis will argue that many Western countries, which were the main beneficiaries of colonialism, continue to ‘other’ Africans, in spite of their claims to respect all human beings. Wicomb’s and Adichie’s novels depict characters that are moving between different continents, along with the impact that this has on them. In the twenty-first century, more people are moving between different spaces and, as a result, interacting with different cultures. These migrations, as this thesis will show, give rise to paradoxical circumstances: people are still being judged according to their race and gender, in spite of the freedom that these moves are supposed to lead to. Of central importance to both novels then is the question of home and belonging. Since people are moving between different continents, is it still possible to belong to one place? Is it in fact possible to belong at all? These are some of the questions that will be raised and answered in this thesis. Lastly, the thesis will look at the thematic representations of reading and writing in the novels under consideration. This is most evident in Adichie’s novel where her main character starts blogging as a way to express her dissatisfaction with the racist and sexist environment she encounters in the United States of America. The thesis will explore how Adichie examines blogging as a mode of communication that is unique to the twenty-first century. It will argue that it is perhaps through new media that historically subjugated subjects, such as African people and women, will be able to express themselves. Less hackneyed modes of communication might provide the necessary channels for those who have historically been denied voice to finally find it.
- Full Text:
- Date Issued: 2016
- Authors: Nthunya, Manosa
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3939 , vital:20559
- Description: This thesis will interrogate the ways in which the most recent novels of Zoë Wicomb and Chimamanda Ngozi Adichie (namely October and Americanah) explore race, gender and transnational issues. Wicomb and Adichie share an interest in representing the lives of people who have been historically marginalised by racial and gender classifications. This thesis will argue that historical and stereotypical ways of looking at people, particularly African people, are still prevalent in the twenty-first century. Wicomb’s interest is in the coloured community and the impact that apartheid ideology has had on it. She shows, as this thesis will argue, that notions of shame and respectability still influence the coloured community, post-1994, in the same ways they did under apartheid. Furthermore, the thesis will show that religion, which was used to justify apartheid, has been instrumental in maintaining racist and sexist norms in the coloured community in post-apartheid South Africa. Adichie’s novel, on the other hand, shows the impact of gender norms in Nigeria on her female characters. Unlike characters in Wicomb’s novel, Adichie’s mostly experience racial bias when they move to Western countries. This thesis will argue that many Western countries, which were the main beneficiaries of colonialism, continue to ‘other’ Africans, in spite of their claims to respect all human beings. Wicomb’s and Adichie’s novels depict characters that are moving between different continents, along with the impact that this has on them. In the twenty-first century, more people are moving between different spaces and, as a result, interacting with different cultures. These migrations, as this thesis will show, give rise to paradoxical circumstances: people are still being judged according to their race and gender, in spite of the freedom that these moves are supposed to lead to. Of central importance to both novels then is the question of home and belonging. Since people are moving between different continents, is it still possible to belong to one place? Is it in fact possible to belong at all? These are some of the questions that will be raised and answered in this thesis. Lastly, the thesis will look at the thematic representations of reading and writing in the novels under consideration. This is most evident in Adichie’s novel where her main character starts blogging as a way to express her dissatisfaction with the racist and sexist environment she encounters in the United States of America. The thesis will explore how Adichie examines blogging as a mode of communication that is unique to the twenty-first century. It will argue that it is perhaps through new media that historically subjugated subjects, such as African people and women, will be able to express themselves. Less hackneyed modes of communication might provide the necessary channels for those who have historically been denied voice to finally find it.
- Full Text:
- Date Issued: 2016
The pattern-richness of graphical passwords
- Vorster, Johannes, Van Heerden, Renier, Irwin, Barry V W
- Authors: Vorster, Johannes , Van Heerden, Renier , Irwin, Barry V W
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/68322 , vital:29238 , https://doi.org/10.1109/ISSA.2016.7802931
- Description: Publisher version , Conventional (text-based) passwords have shown patterns such as variations on the username, or known passwords such as “password”, “admin” or “12345”. Patterns may similarly be detected in the use of Graphical passwords (GPs). The most significant such pattern - reported by many researchers - is hotspot clustering. This paper qualitatively analyses more than 200 graphical passwords for patterns other than the classically reported hotspots. The qualitative analysis finds that a significant percentage of passwords fall into a small set of patterns; patterns that can be used to form attack models against GPs. In counter action, these patterns can also be used to educate users so that future password selection is more secure. It is the hope that the outcome from this research will lead to improved behaviour and an enhancement in graphical password security.
- Full Text: false
- Date Issued: 2016
- Authors: Vorster, Johannes , Van Heerden, Renier , Irwin, Barry V W
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/68322 , vital:29238 , https://doi.org/10.1109/ISSA.2016.7802931
- Description: Publisher version , Conventional (text-based) passwords have shown patterns such as variations on the username, or known passwords such as “password”, “admin” or “12345”. Patterns may similarly be detected in the use of Graphical passwords (GPs). The most significant such pattern - reported by many researchers - is hotspot clustering. This paper qualitatively analyses more than 200 graphical passwords for patterns other than the classically reported hotspots. The qualitative analysis finds that a significant percentage of passwords fall into a small set of patterns; patterns that can be used to form attack models against GPs. In counter action, these patterns can also be used to educate users so that future password selection is more secure. It is the hope that the outcome from this research will lead to improved behaviour and an enhancement in graphical password security.
- Full Text: false
- Date Issued: 2016
The perceptions of nurse educators regarding the use of high-fidelity simulation in nursing education at a South African private nursing college
- Authors: Janse van Vuuren, S V
- Date: 2016
- Subjects: Nursing -- Study and teaching -- Simulation methods Simulated patients
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10353/1752 , vital:27555
- Description: Although Nurse Educators are aware of the advantages of simulation-based training, some still feel uncomfortable to use technology or lack the motivation to learn how to use the technology. The aging population of nurse educators cause frustration and anxiety. They struggle with how to include these tools, particularly in the light of faculty shortages. Nursing education programmes are increasingly adopting simulation in both undergraduate and graduate curricula. Scoping literature reviews show that nursing practice has changed in recent years, placing demands on nurse educators to utilise different approaches in education. The fact that nurse educators are an aging population needs to be taken into consideration and acknowledge that many of them did not grow up with computers and lag behind in technological skills. The aim of this study was to investigate the perceptions of nurse educators regarding the use of high-fidelity simulation in nursing education at a South African Private Nursing College in order to be able to determine why High-fidelity Simulators (HFS) have not yet been embraced by nurse educators and students. A national survey of nurse educators and clinical training specialists was completed with 128 participants; but only 79 completed the survey. In addition to background information, participants were questioned about their use of simulators. They were asked to complete the Technology Readiness Index. Information was also obtained regarding their perceptions of the use of HFS. Findings included indications that everyone is at the same level as far as technology readiness is concerned; this, however, does not play a large role in the use of HFS. This finding supports the educators’ need for training to adequately prepare them to use simulation equipment. Recommendations for further study include research to determine what other factors play a role in the use of HFS, studies to determine whether the benefits of HFS are superior to other teaching strategies warranting the time and financial commitment. The results of this study can be used as guidelines for other institutions to prepare their teaching staff for the use of HFS.
- Full Text:
- Date Issued: 2016
- Authors: Janse van Vuuren, S V
- Date: 2016
- Subjects: Nursing -- Study and teaching -- Simulation methods Simulated patients
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10353/1752 , vital:27555
- Description: Although Nurse Educators are aware of the advantages of simulation-based training, some still feel uncomfortable to use technology or lack the motivation to learn how to use the technology. The aging population of nurse educators cause frustration and anxiety. They struggle with how to include these tools, particularly in the light of faculty shortages. Nursing education programmes are increasingly adopting simulation in both undergraduate and graduate curricula. Scoping literature reviews show that nursing practice has changed in recent years, placing demands on nurse educators to utilise different approaches in education. The fact that nurse educators are an aging population needs to be taken into consideration and acknowledge that many of them did not grow up with computers and lag behind in technological skills. The aim of this study was to investigate the perceptions of nurse educators regarding the use of high-fidelity simulation in nursing education at a South African Private Nursing College in order to be able to determine why High-fidelity Simulators (HFS) have not yet been embraced by nurse educators and students. A national survey of nurse educators and clinical training specialists was completed with 128 participants; but only 79 completed the survey. In addition to background information, participants were questioned about their use of simulators. They were asked to complete the Technology Readiness Index. Information was also obtained regarding their perceptions of the use of HFS. Findings included indications that everyone is at the same level as far as technology readiness is concerned; this, however, does not play a large role in the use of HFS. This finding supports the educators’ need for training to adequately prepare them to use simulation equipment. Recommendations for further study include research to determine what other factors play a role in the use of HFS, studies to determine whether the benefits of HFS are superior to other teaching strategies warranting the time and financial commitment. The results of this study can be used as guidelines for other institutions to prepare their teaching staff for the use of HFS.
- Full Text:
- Date Issued: 2016
The perceptions of teachers teaching mathematical literacy at Further Education and Training level : a case study conducted in the East London District
- Pillai, Sivarama Panicker Mohanan
- Authors: Pillai, Sivarama Panicker Mohanan
- Date: 2016
- Subjects: Mathematics--Study and teaching--South Africa--Eastern Cape Education, Higher--South Africa--Eastern Cape--Administration
- Language: English
- Type: Thesis , Masters , Education
- Identifier: http://hdl.handle.net/10353/15980 , vital:40571
- Description: Mathematical Literacy is a compulsory subject at the Further Education and Training (FET) level in South Africa. All learners who do not select Mathematics are required to study Mathematical Literacy as their numeracy subject in Grade 10, the first year of studying at the FET level. This requirement coincided with the educational reforms which were introduced in South Africa after democracy was attained in1994. Mathematical Literacy was introduced in Grade 10 in 2008, in Grade 11 in 2009 and in Grade 12 in 2010. Matriculants in 2012 comprised the cohort who wrote the Mathematical Literacy examination for the first time in South African history. Although 4 years have passed since the introduction of Mathematical Literacy in Grade 12, many teachers are still not sufficiently competent enough to teach the subject. This fact has been demonstrated quite conclusively in the matriculation results of the past 4 years. The failure to teach the subject satisfactorily is the result of poor knowledge of the content of the courses, insufficient teaching materials and incorrect teaching methods. This study has focused on uncovering the perceptions of teachers of the teaching of Mathematical Literacy and on how best to support and assist teachers in order to improve their knowledge of the content of their courses, to improve the methods of teaching the subject and to provide sufficient resources to support both teaching and learning. The study is also aimed to draw the attention of the Department of Education (DoE) to the need to provide better training in order to develop the competency of teachers in the subject and to overcome the lack of resources through developing innovative ways of teaching it. A qualitative approach was adopted in order to conduct the research, as it aims to provide an explicit rendering of the structure, order and broad patterns pertaining to the teaching of the subject from a group of participants. Qualitative research is best suited to studies of this sort, as it provides the means to conduct an in-depth investigation of the thoughts, beliefs, attitudes and responses of teachers concerning the teaching of Mathematical Literacy at the FET level. The research was conducted in 6 FET schools in the East London Education District. Six teachers of Mathematics and Mathematical Literacy in Grades 10, 11 and 12 were selected to comprise the research sample for the study. Semi-structured questions were used to collect the data. The research study established that educators have divergent perceptions and beliefs concerning the teaching of Mathematical Literacy at the FET level. The study was also able to identify the problems, obstacles and difficulties encountered by the teachers in their attempts to teach the subject and the trends which emerged during the conducting of the research.
- Full Text:
- Date Issued: 2016
- Authors: Pillai, Sivarama Panicker Mohanan
- Date: 2016
- Subjects: Mathematics--Study and teaching--South Africa--Eastern Cape Education, Higher--South Africa--Eastern Cape--Administration
- Language: English
- Type: Thesis , Masters , Education
- Identifier: http://hdl.handle.net/10353/15980 , vital:40571
- Description: Mathematical Literacy is a compulsory subject at the Further Education and Training (FET) level in South Africa. All learners who do not select Mathematics are required to study Mathematical Literacy as their numeracy subject in Grade 10, the first year of studying at the FET level. This requirement coincided with the educational reforms which were introduced in South Africa after democracy was attained in1994. Mathematical Literacy was introduced in Grade 10 in 2008, in Grade 11 in 2009 and in Grade 12 in 2010. Matriculants in 2012 comprised the cohort who wrote the Mathematical Literacy examination for the first time in South African history. Although 4 years have passed since the introduction of Mathematical Literacy in Grade 12, many teachers are still not sufficiently competent enough to teach the subject. This fact has been demonstrated quite conclusively in the matriculation results of the past 4 years. The failure to teach the subject satisfactorily is the result of poor knowledge of the content of the courses, insufficient teaching materials and incorrect teaching methods. This study has focused on uncovering the perceptions of teachers of the teaching of Mathematical Literacy and on how best to support and assist teachers in order to improve their knowledge of the content of their courses, to improve the methods of teaching the subject and to provide sufficient resources to support both teaching and learning. The study is also aimed to draw the attention of the Department of Education (DoE) to the need to provide better training in order to develop the competency of teachers in the subject and to overcome the lack of resources through developing innovative ways of teaching it. A qualitative approach was adopted in order to conduct the research, as it aims to provide an explicit rendering of the structure, order and broad patterns pertaining to the teaching of the subject from a group of participants. Qualitative research is best suited to studies of this sort, as it provides the means to conduct an in-depth investigation of the thoughts, beliefs, attitudes and responses of teachers concerning the teaching of Mathematical Literacy at the FET level. The research was conducted in 6 FET schools in the East London Education District. Six teachers of Mathematics and Mathematical Literacy in Grades 10, 11 and 12 were selected to comprise the research sample for the study. Semi-structured questions were used to collect the data. The research study established that educators have divergent perceptions and beliefs concerning the teaching of Mathematical Literacy at the FET level. The study was also able to identify the problems, obstacles and difficulties encountered by the teachers in their attempts to teach the subject and the trends which emerged during the conducting of the research.
- Full Text:
- Date Issued: 2016
The perfomance of South African pilots on cognitive ability assessment
- Authors: Simpson, Sinombongo Mazulu
- Date: 2016
- Subjects: Intelligence tests -- South Africa , Airplanes -- Piloting -- Ability testing -- South Africa , Air pilots -- Social conditions
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/12813 , vital:27123
- Description: In South Africa, the issue of lack of black pilot skills is a most talked about topic in commercial airlines. Airlines need to find the right set of skills and attitude to operate safely and successfully. Airline safety remains a topic of discussion, therefore airlines need ensure robustness of their selection processes. There are many requirements that a person has to meet before s/he can be offered a first officer job at an airline. The majority of the pilots in South Africa are white males. The study aimed to determine if there are statistically significant differences in cognitive ability test results between Black and White applicants for pilot positions with a South Africa airline. The test battery included a verbal reasoning test, numerical reasoning test, visual thinking, abstract reasoning test, spatial reasoning test, short term memory test, monitoring ability test, hand-eye coordination, sense of orientation test, reactivity test, and a multi-tasking test. The data were extracted with permission from a database maintained on behalf of the airline by an online test provider and subjected to a statistical analysis using measures of central tendency, and spread, in order to report on the significance of the differences between the groups. There is strong evidence that the White group performed better than the Black group on the majority of the tests. It is recommended that further research is done in order to determine the causes of these differences. A comparative study of results on other airlines’ recruitment selection tests and an exploratory study of the impact of socio-economic factors, education quality and language on cognitive ability tests are recommended.
- Full Text:
- Date Issued: 2016
- Authors: Simpson, Sinombongo Mazulu
- Date: 2016
- Subjects: Intelligence tests -- South Africa , Airplanes -- Piloting -- Ability testing -- South Africa , Air pilots -- Social conditions
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/12813 , vital:27123
- Description: In South Africa, the issue of lack of black pilot skills is a most talked about topic in commercial airlines. Airlines need to find the right set of skills and attitude to operate safely and successfully. Airline safety remains a topic of discussion, therefore airlines need ensure robustness of their selection processes. There are many requirements that a person has to meet before s/he can be offered a first officer job at an airline. The majority of the pilots in South Africa are white males. The study aimed to determine if there are statistically significant differences in cognitive ability test results between Black and White applicants for pilot positions with a South Africa airline. The test battery included a verbal reasoning test, numerical reasoning test, visual thinking, abstract reasoning test, spatial reasoning test, short term memory test, monitoring ability test, hand-eye coordination, sense of orientation test, reactivity test, and a multi-tasking test. The data were extracted with permission from a database maintained on behalf of the airline by an online test provider and subjected to a statistical analysis using measures of central tendency, and spread, in order to report on the significance of the differences between the groups. There is strong evidence that the White group performed better than the Black group on the majority of the tests. It is recommended that further research is done in order to determine the causes of these differences. A comparative study of results on other airlines’ recruitment selection tests and an exploratory study of the impact of socio-economic factors, education quality and language on cognitive ability tests are recommended.
- Full Text:
- Date Issued: 2016
The personal financial management attitudes and practices of South African rugby players
- Authors: Acker, Enrico
- Date: 2016
- Subjects: Rugby football players -- South Africa -- Finance, Personal Finance, Personal -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/11363 , vital:26915
- Description: When rugby became professional in 1995, both the game and the social and financial position of the players changed (Basson, 2003). Players started to train full-time and earned annual salaries (Goldman& Johns, 2009). Due to the transition from amateur to professional status, rugby players needed to make adequate personal financial management decisions. The purpose of this study is to investigate the personal financial management attitudes and practices of South African rugby players. Previous research about personal financial management largely focussed on the general public, and did not focus on South African rugby players. Rugby is a professional sport where players earn money from a young age. It is expected of rugby players to make adequate personal financial decisions from as early as 19 years old. The literature review provided an overview of personal financial management and a discussion on the various components that should be included in personal financial management. A framework for this study was developed. The framework used these components as the base for the personal financial attitudes and practices and how it relates to the demographics of the respondents. Three hypotheses were also formulated based on the literature overview and framework. The objectives of this study were achieved by adopting a quantitative research methodology. A convenience sample of 132 rugby players was drawn for this study. Rugby players from NMMU Madibaz, Eastern Province Rugby Union (EP), South Western Districts Rugby Union (SWD) and Sharks Rugby Union participated in this study. The results of the empirical survey showed that respondents have positive attitudes towards the importance of budgeting, retirement planning, risk management, debt management and investment and the importance of employing a financial planner. On the other hand the personal financial management practices of the respondents in this study can be described as weak. From the results of the empirical survey it is clear that the respondents have weak practices towards the majority of the personal financial management practices. Only one of the three hypotheses was accepted namely that there is a relationship between the demographics of rugby players and their personal financial practices. There is no relationship between personal financial management attitudes and personal financial management practices of South African rugby players and that there is also no relationship between demographic variables and personal financial management attitudes of South African rugby players. This study has provided insight into the personal financial management attitudes and practices of South African rugby players. Valuable information was obtained that could help to address the personal financial management needs of rugby players.
- Full Text:
- Date Issued: 2016
- Authors: Acker, Enrico
- Date: 2016
- Subjects: Rugby football players -- South Africa -- Finance, Personal Finance, Personal -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/11363 , vital:26915
- Description: When rugby became professional in 1995, both the game and the social and financial position of the players changed (Basson, 2003). Players started to train full-time and earned annual salaries (Goldman& Johns, 2009). Due to the transition from amateur to professional status, rugby players needed to make adequate personal financial management decisions. The purpose of this study is to investigate the personal financial management attitudes and practices of South African rugby players. Previous research about personal financial management largely focussed on the general public, and did not focus on South African rugby players. Rugby is a professional sport where players earn money from a young age. It is expected of rugby players to make adequate personal financial decisions from as early as 19 years old. The literature review provided an overview of personal financial management and a discussion on the various components that should be included in personal financial management. A framework for this study was developed. The framework used these components as the base for the personal financial attitudes and practices and how it relates to the demographics of the respondents. Three hypotheses were also formulated based on the literature overview and framework. The objectives of this study were achieved by adopting a quantitative research methodology. A convenience sample of 132 rugby players was drawn for this study. Rugby players from NMMU Madibaz, Eastern Province Rugby Union (EP), South Western Districts Rugby Union (SWD) and Sharks Rugby Union participated in this study. The results of the empirical survey showed that respondents have positive attitudes towards the importance of budgeting, retirement planning, risk management, debt management and investment and the importance of employing a financial planner. On the other hand the personal financial management practices of the respondents in this study can be described as weak. From the results of the empirical survey it is clear that the respondents have weak practices towards the majority of the personal financial management practices. Only one of the three hypotheses was accepted namely that there is a relationship between the demographics of rugby players and their personal financial practices. There is no relationship between personal financial management attitudes and personal financial management practices of South African rugby players and that there is also no relationship between demographic variables and personal financial management attitudes of South African rugby players. This study has provided insight into the personal financial management attitudes and practices of South African rugby players. Valuable information was obtained that could help to address the personal financial management needs of rugby players.
- Full Text:
- Date Issued: 2016
The philanthropic priorities of Chinese and Japanese Americans as they relate to Asian American culturally specific museums
- Authors: Yok, Larry Tom
- Date: 2016
- Subjects: Museums -- Economic aspects -- United States Chinese Americans -- Development -- United States Non-governmental organizations -- Museums -- Economic aspects
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/13160 , vital:27157
- Description: Asian American culturally specific museums began forming in the United States in 1963. There are now 11 in existence. Four of these museums (two Chinese American, one Japanese American and one Pan Asian American) dramatically expanded their programs and constructed large new facilities. These culturally specific museums are private nonprofit organizations that are reliant on private donors for most of their financial support. Asian Americans comprise the majority of these Asian American museums’ donor bases. Understanding why donors support these museums may be useful to the museums’ abilities to raise funds.In this thesis I explore the reasons Chinese and Japanese Americans support these culturally specific museums. I used data from my qualitative study involving in-depth interviews of 16 Chinese and Japanese American current and former donors to a Pan Asian culturally specific museum in Seattle, Washington along with interviews of chief executives and other key informants of five other culturally specific museums in addition to primary documents provided by the museums and related secondary information available through the Internet. I also conducted a literature review in the fields of Development Studies, racial and ethnic identity, museology, and philanthropy. While identifying the reasons donors support these culturally specific museums, I also identify the philanthropic priorities and criteria of Chinese and Japanese Americans residing in Seattle and compare them with similar studies of Asian American philanthropy conducted in other cities in the 1990’s. I also examine the roles played by these culturally specific museums in the promotion of social capital, cultural capital and heritage capital in their communities. Chinese and Japanese Americans support these museums to preserve and educate their communities about the contributions their forebears made to the development of the United States. Asian American history has been marginalized in conventional narratives and one mission of the Asian American culturally specific museums is to bring their stories into the American history mainstream. Creating and operating these museums requires substantial networking within the Chinese and Japanese American communities and with other ethnic communities to bring in visitors and obtain financial and other support. The museums promote social capital development through collaboration in the museums’ operations. They increase the communities’ cultural capital by assembling the dispersed cultural and heritage capital of the Chinese and Japanese American communities into curated collections. These Asian American culturally specific museums face challenges stemming from attrition in their donor bases due to age. The museums need to develop activities that attract new supporters who may be mixed race or mixed ethnicity or who are interested in social activism that impacts society. The museums also must create programs that are relevant to younger generations. The findings of this study lay the groundwork for further inquiry into the ways culturally specific museums promote bonding and bridging capital in low and middle class Asian American communities and the degree to which they affect development in their neighbourhoods. Further research into the museums’ educational programs efficacy as they relate to correcting misperceptions about Asian Americans among non-Asian Americans may be desirable.
- Full Text:
- Date Issued: 2016
- Authors: Yok, Larry Tom
- Date: 2016
- Subjects: Museums -- Economic aspects -- United States Chinese Americans -- Development -- United States Non-governmental organizations -- Museums -- Economic aspects
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/13160 , vital:27157
- Description: Asian American culturally specific museums began forming in the United States in 1963. There are now 11 in existence. Four of these museums (two Chinese American, one Japanese American and one Pan Asian American) dramatically expanded their programs and constructed large new facilities. These culturally specific museums are private nonprofit organizations that are reliant on private donors for most of their financial support. Asian Americans comprise the majority of these Asian American museums’ donor bases. Understanding why donors support these museums may be useful to the museums’ abilities to raise funds.In this thesis I explore the reasons Chinese and Japanese Americans support these culturally specific museums. I used data from my qualitative study involving in-depth interviews of 16 Chinese and Japanese American current and former donors to a Pan Asian culturally specific museum in Seattle, Washington along with interviews of chief executives and other key informants of five other culturally specific museums in addition to primary documents provided by the museums and related secondary information available through the Internet. I also conducted a literature review in the fields of Development Studies, racial and ethnic identity, museology, and philanthropy. While identifying the reasons donors support these culturally specific museums, I also identify the philanthropic priorities and criteria of Chinese and Japanese Americans residing in Seattle and compare them with similar studies of Asian American philanthropy conducted in other cities in the 1990’s. I also examine the roles played by these culturally specific museums in the promotion of social capital, cultural capital and heritage capital in their communities. Chinese and Japanese Americans support these museums to preserve and educate their communities about the contributions their forebears made to the development of the United States. Asian American history has been marginalized in conventional narratives and one mission of the Asian American culturally specific museums is to bring their stories into the American history mainstream. Creating and operating these museums requires substantial networking within the Chinese and Japanese American communities and with other ethnic communities to bring in visitors and obtain financial and other support. The museums promote social capital development through collaboration in the museums’ operations. They increase the communities’ cultural capital by assembling the dispersed cultural and heritage capital of the Chinese and Japanese American communities into curated collections. These Asian American culturally specific museums face challenges stemming from attrition in their donor bases due to age. The museums need to develop activities that attract new supporters who may be mixed race or mixed ethnicity or who are interested in social activism that impacts society. The museums also must create programs that are relevant to younger generations. The findings of this study lay the groundwork for further inquiry into the ways culturally specific museums promote bonding and bridging capital in low and middle class Asian American communities and the degree to which they affect development in their neighbourhoods. Further research into the museums’ educational programs efficacy as they relate to correcting misperceptions about Asian Americans among non-Asian Americans may be desirable.
- Full Text:
- Date Issued: 2016
The photobleaching of the free and encapsulated metallic phthalocyanine and its effect on the photooxidation of simple molecules
- Fanchiotti, Brenda Gomes, Machado, Marcella Piffer Zamprogno, de Paula, Letícia Camilato, Durmuş, Mahmut, Nyokong, Tebello, da Silva, Gonçalves, da Silva, André Romero
- Authors: Fanchiotti, Brenda Gomes , Machado, Marcella Piffer Zamprogno , de Paula, Letícia Camilato , Durmuş, Mahmut , Nyokong, Tebello , da Silva, Gonçalves , da Silva, André Romero
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/239687 , vital:50755 , xlink:href="https://doi.org/10.1016/j.jphotobiol.2016.10.007"
- Description: The photobleaching of an unsubstituted phthalocyanine (gallium(III) phthalocyanine chloride (GaPc)) and a substituted phthalocyanine (1,4-(tetrakis[4-(benzyloxy)phenoxy]phthalocyaninato) indium(III) chloride (InTBPPc)) was monitored for the free photosensitizers and for the phthalocyanines encapsulated into nanoparticles of PEGylated poly(D,L-lactide-co-glycolide) (PLGA-PEG). Phosphate-buffered solutions (PBS) and organic solutions of the free GaPc or the free InTBPPc, and suspensions of each encapsulated photosensitizer (2–15 μmol/L) were irradiated using a laser diode of 665 nm with a power of 1–104 mW and a light dose of 7.5 J/cm2. The relative absorbance (RA) of the free GaPc dissolved in 1-methyl-2-pyrrolidone (MP) decreased 8.4 times when the laser power increased from 1 mW to 104 mW. However, the free or encapsulated GaPc did not suffer the photobleaching in PBS solution. The RA values decreased 2.4 times and 22.2 times for the free InTBPPc dissolved in PBS solution and in dimethylformamide (DMF), respectively, but the encapsulated InTBPPc was only photobleached when the laser power was 104 mW at 8 μmol/L. The increase of the free GaPc concentration favored the photobleaching in MP until 8 μmol/L while the increase from 2 μmol/L to 5 μmol/L reduced the photodegradation in PBS solution. However, the photobleaching of the free InTBPPc in DMF or in PBS solution, and of each encapsulated photosensitizer was not influenced by increasing the concentration. The influence of the photobleaching on the capability of the free and encapsulated GaPc and InTBPPc to photooxidate the simple molecules was investigated monitoring the fluorescence of dimethylanthracene (DMA) and the tryptophan (Trp). Free InTBPPc was 2.0 and 1.8 times faster to photooxidate the DMA and Trp than it was the free GaPc, but the encapsulated GaPc was 3.4 times more efficient to photooxidize the Trp than it was the encapsulated InTBPPc due to the photodegradation suffered by the encapsulated InTBPPc. The participation of the singlet oxygen was confirmed with the sodium azide in the photobleaching of all free and encapsulated photosensitizer, and in the photooxidation of the DMA and Trp. The asymmetry of InTBPPc increased the solubility of the free compound, decreasing the aggregation state of the photosensitizer and favoring the photobleaching process. The encapsulation shows capability in decreasing the photobleaching of both photosensitizers but the confocal micrographs showed that the increase of the solubility favored the InTBPPc photobleaching during the acquisition of optical cross section. A novel low-symmetry A3B-type phthalocyanine annelated with a pyrazino[2,3-f]phenanthroline ring system and substituted with six solubilizing diisopropylphenoxy-groups (1) was synthesized by metalfree DBU-promoted cross-condensation of diiminoisoindolines derived from 4,5- bis(diisopropylphenoxy)phthalonitrile and pyrazino[2,3-f][1,10]phenanthroline-2,3-dicarbonitrile. The use of these particular precursors affords A3B phthalocyanine in 15% yield, while cross-condensation of the corresponding dinitriles yields only trace amounts of the target compound. Comparative studies of the A3B-type phthalocyanine and its symmetrical octa(diisopropylphenoxy)-substituted counterpart 2 reveal striking differences in the Q band regions of their UVevisible absorption (UVeVis) spectra, which could be readily rationalized through a comparison with calculated TD-DFT spectra. Since 1 can have two NH-tautomers with equivalent and non-equivalent NH-groups, and DFT calculations predict that the former tautomer is only 2.3 kcal/mol more stable than the latter one, a comprehensive analysis of 13C NMR spectra was carried out through the application of 1 He13C HMBC and HSQC techniques. It demonstrated that only the tautomer with equivalent NH-groups is present in solution.
- Full Text:
- Date Issued: 2016
- Authors: Fanchiotti, Brenda Gomes , Machado, Marcella Piffer Zamprogno , de Paula, Letícia Camilato , Durmuş, Mahmut , Nyokong, Tebello , da Silva, Gonçalves , da Silva, André Romero
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/239687 , vital:50755 , xlink:href="https://doi.org/10.1016/j.jphotobiol.2016.10.007"
- Description: The photobleaching of an unsubstituted phthalocyanine (gallium(III) phthalocyanine chloride (GaPc)) and a substituted phthalocyanine (1,4-(tetrakis[4-(benzyloxy)phenoxy]phthalocyaninato) indium(III) chloride (InTBPPc)) was monitored for the free photosensitizers and for the phthalocyanines encapsulated into nanoparticles of PEGylated poly(D,L-lactide-co-glycolide) (PLGA-PEG). Phosphate-buffered solutions (PBS) and organic solutions of the free GaPc or the free InTBPPc, and suspensions of each encapsulated photosensitizer (2–15 μmol/L) were irradiated using a laser diode of 665 nm with a power of 1–104 mW and a light dose of 7.5 J/cm2. The relative absorbance (RA) of the free GaPc dissolved in 1-methyl-2-pyrrolidone (MP) decreased 8.4 times when the laser power increased from 1 mW to 104 mW. However, the free or encapsulated GaPc did not suffer the photobleaching in PBS solution. The RA values decreased 2.4 times and 22.2 times for the free InTBPPc dissolved in PBS solution and in dimethylformamide (DMF), respectively, but the encapsulated InTBPPc was only photobleached when the laser power was 104 mW at 8 μmol/L. The increase of the free GaPc concentration favored the photobleaching in MP until 8 μmol/L while the increase from 2 μmol/L to 5 μmol/L reduced the photodegradation in PBS solution. However, the photobleaching of the free InTBPPc in DMF or in PBS solution, and of each encapsulated photosensitizer was not influenced by increasing the concentration. The influence of the photobleaching on the capability of the free and encapsulated GaPc and InTBPPc to photooxidate the simple molecules was investigated monitoring the fluorescence of dimethylanthracene (DMA) and the tryptophan (Trp). Free InTBPPc was 2.0 and 1.8 times faster to photooxidate the DMA and Trp than it was the free GaPc, but the encapsulated GaPc was 3.4 times more efficient to photooxidize the Trp than it was the encapsulated InTBPPc due to the photodegradation suffered by the encapsulated InTBPPc. The participation of the singlet oxygen was confirmed with the sodium azide in the photobleaching of all free and encapsulated photosensitizer, and in the photooxidation of the DMA and Trp. The asymmetry of InTBPPc increased the solubility of the free compound, decreasing the aggregation state of the photosensitizer and favoring the photobleaching process. The encapsulation shows capability in decreasing the photobleaching of both photosensitizers but the confocal micrographs showed that the increase of the solubility favored the InTBPPc photobleaching during the acquisition of optical cross section. A novel low-symmetry A3B-type phthalocyanine annelated with a pyrazino[2,3-f]phenanthroline ring system and substituted with six solubilizing diisopropylphenoxy-groups (1) was synthesized by metalfree DBU-promoted cross-condensation of diiminoisoindolines derived from 4,5- bis(diisopropylphenoxy)phthalonitrile and pyrazino[2,3-f][1,10]phenanthroline-2,3-dicarbonitrile. The use of these particular precursors affords A3B phthalocyanine in 15% yield, while cross-condensation of the corresponding dinitriles yields only trace amounts of the target compound. Comparative studies of the A3B-type phthalocyanine and its symmetrical octa(diisopropylphenoxy)-substituted counterpart 2 reveal striking differences in the Q band regions of their UVevisible absorption (UVeVis) spectra, which could be readily rationalized through a comparison with calculated TD-DFT spectra. Since 1 can have two NH-tautomers with equivalent and non-equivalent NH-groups, and DFT calculations predict that the former tautomer is only 2.3 kcal/mol more stable than the latter one, a comprehensive analysis of 13C NMR spectra was carried out through the application of 1 He13C HMBC and HSQC techniques. It demonstrated that only the tautomer with equivalent NH-groups is present in solution.
- Full Text:
- Date Issued: 2016
The physical activity and health-related fitness of female students at a South African university
- Authors: Baatjes, Tashrique
- Date: 2016
- Subjects: Physical fitness for women Physical education and training Women college students -- Health and hygiene Health behavior
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/5575 , vital:20909
- Description: Physical inactivity and resultant chronic diseases of lifestyle (CDLs) are becoming a global epidemic as secular modernization and the sedentary lifestyles it brings with it become universal. The importance of physical activity (PA) in reducing morbidity and mortality from CDLs and related conditions has been well established. Since it is generally significant that the onset of many CDLs lies in childhood through to adolescence, preventative strategies should start as early in life as possible. Currently, university students are failing to engage in the levels of PA recommended for better health outcomes over the short and long term. To make matters worse, there is increasing evidence of a decrease in PA during the transitional phase from adolescence to adulthood. This study aimed to determine the physical activity (PA) levels, sedentary behaviour and health-related fitness (HRF) characteristics of female university students. In addition, the participants‘ perceived barriers to PA were investigated. The study was exploratory-descriptive and employed a quantitative research design. Five hundred and thirty-one full-time female students, between the ages of 18 and 46, studying at Nelson Mandela Metropolitan University‘s (NMMU) South, North, Second Avenue and Missionvale campuses participated in the study. The participants (n=531) completed an online survey which determined their PA levels, sedentary behaviours and perceived barriers to PA participation. A health-related fitness (HRF) assessment was also administered to 68 participants who completed the online survey. Their height, weight, and waist and hip circumferences were measured, as well as their cardiovascular fitness (CF). The majority (88 percent) of the participants reported low and minimal levels of PA, and 44 percent were either overweight or obese. The participants had a low-risk waist-to-hip ratio (WHR) (M=0.70). The majority of the population (94 percent) had poor cardiovascular fitness (CF). A high prevalence of sitting time was recorded among the participants: on average 855 minutes (14 hours) on a usual weekday and 720 minutes (12 hours) on a usual weekend day. Students reported the greatest length of sitting time at work/attending lectures/studying. Cross tabulations and Chi2 tests indicated no significant relationships among PA and HRF (BMI, WHR and CF) and sedentary behaviour and HRF. The ANOVA and t-test results for PA, sedentary behaviour and HRF related to various demographic variables, found small (0.19 < d < 0.50) and medium (0.49 < d < 0.80) significant differences by race (d=0.43; d=0.52), home language (d=0.41; d=0.44) and living arrangement (d=0.38; d=0.28). No significant relationship was found to exist between age, year of study and faculty of registration and sedentary behaviour or HRF. The participants listed: Not enough time; too expensive to exercise; and, no friends who can exercise with me as the most important barriers to participation in PA. Academic obligations (3.08 mean) was found to be the most important barrier to PA.
- Full Text:
- Date Issued: 2016
- Authors: Baatjes, Tashrique
- Date: 2016
- Subjects: Physical fitness for women Physical education and training Women college students -- Health and hygiene Health behavior
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/5575 , vital:20909
- Description: Physical inactivity and resultant chronic diseases of lifestyle (CDLs) are becoming a global epidemic as secular modernization and the sedentary lifestyles it brings with it become universal. The importance of physical activity (PA) in reducing morbidity and mortality from CDLs and related conditions has been well established. Since it is generally significant that the onset of many CDLs lies in childhood through to adolescence, preventative strategies should start as early in life as possible. Currently, university students are failing to engage in the levels of PA recommended for better health outcomes over the short and long term. To make matters worse, there is increasing evidence of a decrease in PA during the transitional phase from adolescence to adulthood. This study aimed to determine the physical activity (PA) levels, sedentary behaviour and health-related fitness (HRF) characteristics of female university students. In addition, the participants‘ perceived barriers to PA were investigated. The study was exploratory-descriptive and employed a quantitative research design. Five hundred and thirty-one full-time female students, between the ages of 18 and 46, studying at Nelson Mandela Metropolitan University‘s (NMMU) South, North, Second Avenue and Missionvale campuses participated in the study. The participants (n=531) completed an online survey which determined their PA levels, sedentary behaviours and perceived barriers to PA participation. A health-related fitness (HRF) assessment was also administered to 68 participants who completed the online survey. Their height, weight, and waist and hip circumferences were measured, as well as their cardiovascular fitness (CF). The majority (88 percent) of the participants reported low and minimal levels of PA, and 44 percent were either overweight or obese. The participants had a low-risk waist-to-hip ratio (WHR) (M=0.70). The majority of the population (94 percent) had poor cardiovascular fitness (CF). A high prevalence of sitting time was recorded among the participants: on average 855 minutes (14 hours) on a usual weekday and 720 minutes (12 hours) on a usual weekend day. Students reported the greatest length of sitting time at work/attending lectures/studying. Cross tabulations and Chi2 tests indicated no significant relationships among PA and HRF (BMI, WHR and CF) and sedentary behaviour and HRF. The ANOVA and t-test results for PA, sedentary behaviour and HRF related to various demographic variables, found small (0.19 < d < 0.50) and medium (0.49 < d < 0.80) significant differences by race (d=0.43; d=0.52), home language (d=0.41; d=0.44) and living arrangement (d=0.38; d=0.28). No significant relationship was found to exist between age, year of study and faculty of registration and sedentary behaviour or HRF. The participants listed: Not enough time; too expensive to exercise; and, no friends who can exercise with me as the most important barriers to participation in PA. Academic obligations (3.08 mean) was found to be the most important barrier to PA.
- Full Text:
- Date Issued: 2016
The phytogeography of Southern Mistbelt Forests of the Eastern Cape, South Africa
- Authors: Matiwane, Aviwe
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3224 , vital:20393
- Description: In the Eastern Cape, a moisture gradient (from west to east) exists along the Escarpment where patches of Southern Mistbelt Forests (SMF) occur. There is a notable profusion of plants in these forests, but the factors that drive plant species composition and abundance in these patches is poorly understood and such knowledge is critical if we are to address or mitigate the problems imposed by global change. Many of our ideas on plant community assembly are based on the premise that species differ in their environmental requirements for successful regeneration, especially when young. The aims of this study were to document the floristic diversity of poorly known patches of Southern Mistbelt Forests in the Eastern Cape and identify the environmental factors that influence plant community composition in these forest patches. Twenty six forest patches across the Eastern Cape were sampled. In each forest 400m2 circular plots were constructed. The diameter at breast height and stem counts for the tree species was taken and the % cover of the herbaceous species was recorded. General collections were also made to supplement the plot data in order to obtain a comprehensive flora for each forest patch. All sampling was done during the summer season of 2013 and 2014. Using plot data, Hierarchal Cluster Analysis and Multidimensional Scaling Analysis were done to compare similarities between patches. Plots from the same forest patch clustered which indicated that the species composition in each forest patch was unique. However, this pattern went down when only tree species were considered. Plant diversity also varied between patches; with those located in the east being generally more diverse than those in the west are. Clustering patterns in fragmented communities and differences in species diversity indicate evidence of species “nestedness”. Analysis of nestedness indicated that these forest patches were significantly nested. To identify which environmental variables might be correlated with both species diversity and nestedness, twelve environmental variables was selected for analysis using Canonical Correspondence Analysis and Principal Component Analysis. Results show that Mean Annual Precipitation, Mean Annual Potential Evapotranspiration, and percentage of Organic Matter of the soil were most strongly correlated with the patterns of diversity observed in these forest patches. Regression analysis indicated that Mean Annual Precipitation accounted for most of the variation in species diversity, especially for the herbaceous species. The herbaceous species thus show a greater sensitivity to “climate filtering” as a consequence of rainfall gradients. With the implementation of suitable monitoring programs, changes in abundance or even local extinction of these species can act as an early warning indicator of the possible long-term effects of climate change on forest communities.
- Full Text:
- Date Issued: 2016
- Authors: Matiwane, Aviwe
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3224 , vital:20393
- Description: In the Eastern Cape, a moisture gradient (from west to east) exists along the Escarpment where patches of Southern Mistbelt Forests (SMF) occur. There is a notable profusion of plants in these forests, but the factors that drive plant species composition and abundance in these patches is poorly understood and such knowledge is critical if we are to address or mitigate the problems imposed by global change. Many of our ideas on plant community assembly are based on the premise that species differ in their environmental requirements for successful regeneration, especially when young. The aims of this study were to document the floristic diversity of poorly known patches of Southern Mistbelt Forests in the Eastern Cape and identify the environmental factors that influence plant community composition in these forest patches. Twenty six forest patches across the Eastern Cape were sampled. In each forest 400m2 circular plots were constructed. The diameter at breast height and stem counts for the tree species was taken and the % cover of the herbaceous species was recorded. General collections were also made to supplement the plot data in order to obtain a comprehensive flora for each forest patch. All sampling was done during the summer season of 2013 and 2014. Using plot data, Hierarchal Cluster Analysis and Multidimensional Scaling Analysis were done to compare similarities between patches. Plots from the same forest patch clustered which indicated that the species composition in each forest patch was unique. However, this pattern went down when only tree species were considered. Plant diversity also varied between patches; with those located in the east being generally more diverse than those in the west are. Clustering patterns in fragmented communities and differences in species diversity indicate evidence of species “nestedness”. Analysis of nestedness indicated that these forest patches were significantly nested. To identify which environmental variables might be correlated with both species diversity and nestedness, twelve environmental variables was selected for analysis using Canonical Correspondence Analysis and Principal Component Analysis. Results show that Mean Annual Precipitation, Mean Annual Potential Evapotranspiration, and percentage of Organic Matter of the soil were most strongly correlated with the patterns of diversity observed in these forest patches. Regression analysis indicated that Mean Annual Precipitation accounted for most of the variation in species diversity, especially for the herbaceous species. The herbaceous species thus show a greater sensitivity to “climate filtering” as a consequence of rainfall gradients. With the implementation of suitable monitoring programs, changes in abundance or even local extinction of these species can act as an early warning indicator of the possible long-term effects of climate change on forest communities.
- Full Text:
- Date Issued: 2016