- Title
- Synthesis, characterization and antibacterial studies of metal complexes of substituted thiourea
- Creator
- Zulu, Happy Nonkululeko
- Subject
- Complex compounds
- Subject
- Halides
- Subject
- Ligands
- Date
- 2012-03
- Type
- Master's theses
- Type
- text
- Identifier
- http://hdl.handle.net/10353/24327
- Identifier
- vital:62636
- Description
- Eighteen complexes Co(II), Cu(II), Zn(II), and Fe(III) with phenylthiourea, diethylthiourea, disopropylthiourea and dimethylthiourea were synthesized and characterized by elemental analysis, UV-Vis, FTIR, conductivity measurements. The complexes were formulated as either four coordinate for the metal(II) or six coordinate for Fe(III). The proposed formulations are consistent with the spectroscopic data for the complexes. The single crystal X-ray structure of the Zn(II) complex of phenylthiourea, Co(II) complex of diethylthiourea and Zn(II) complex of diisopropylthiourea are also reported. The X-ray crystal structures for these complexes revealed distorted tetrahedral geometry around the metal ions showed that the metal ions are coordinated to two molecules of the substituted thiourea through the sulphur atom and two either acetates or chlorides ions complete the four-coordinate geometry. The in vitro antibacterial activity of the complexes was studied against six bacterial strains using disc diffusion and broth micro-dilution methods. The complexes showed selective antibacterial activity.
- Description
- Thesis (MSc) -- Faculty of Science and Agriculture, 2012
- Format
- computer
- Format
- online resource
- Format
- application/pdf
- Format
- 1 online resource (125 leaves)
- Format
- Publisher
- University of Fort Hare
- Publisher
- Faculty of Science and Agriculture
- Language
- English
- Rights
- University of Fort Hare
- Rights
- All Rights Reserved
- Rights
- Open Access
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UFH Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | M Sc Chemistry (May 2012) ZULU.pdf | 2 MB | Adobe Acrobat PDF | View Details Download |