Generic substitution: the use of medicinal products containing different salts and implications for safety and efficacy
- Verbeeck, R K, Kanfer, Isadore, Walker, Roderick B
- Authors: Verbeeck, R K , Kanfer, Isadore , Walker, Roderick B
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6445 , http://hdl.handle.net/10962/d1006632
- Description: In their quest to gain early entry of new generic products into the market prior to patent expiration, one of the strategies pursued by generic drug product manufacturers is to incorporate different salts of an approved active pharmaceutical ingredient (API) in a brand company's marketed dosage form and subject such dosage forms to bioequivalence assessment. These initiatives present challenges to regulatory authorities where the decision to approve bioequivalent products containing such pharmaceutical alternatives must be considered in the light of safety and efficacy, and more particularly, with respect to their substitutability. This article describes the various issues and contentions associated with the concept of pharmaceutical alternatives, specifically with respect to the uses of different salts and the implications for safety, efficacy and generic substitution.
- Full Text:
- Date Issued: 2006
- Authors: Verbeeck, R K , Kanfer, Isadore , Walker, Roderick B
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6445 , http://hdl.handle.net/10962/d1006632
- Description: In their quest to gain early entry of new generic products into the market prior to patent expiration, one of the strategies pursued by generic drug product manufacturers is to incorporate different salts of an approved active pharmaceutical ingredient (API) in a brand company's marketed dosage form and subject such dosage forms to bioequivalence assessment. These initiatives present challenges to regulatory authorities where the decision to approve bioequivalent products containing such pharmaceutical alternatives must be considered in the light of safety and efficacy, and more particularly, with respect to their substitutability. This article describes the various issues and contentions associated with the concept of pharmaceutical alternatives, specifically with respect to the uses of different salts and the implications for safety, efficacy and generic substitution.
- Full Text:
- Date Issued: 2006
Fishes of the deep demersal habitat at Ngazidja (Grand Comoro) Island, Western Indian Ocean
- Heemstra, P C, Hissmann, K, Fricke, H
- Authors: Heemstra, P C , Hissmann, K , Fricke, H
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7128 , http://hdl.handle.net/10962/d1010638
- Description: Underwater observations of the coelacanth, Latimeria chalumnae Smith, 1939, from a research submersible provided opportunities to study the deep demersal fish fauna at the Comoro Islands. The demersal habitat in depths of 150–400 m at the volcanic island of Ngazidja is low in fish diversity and biomass, compared with the shallow-water coral reef habitat of Ngazidja or the deep demersal habitats of other localities in the Indo-Pacific region. The resident deep demersal fish fauna at Ngazidja is dominated by the coelacanth, an ancient predator that is specially adapted for this low-energy environment. Other large fish predators are scarce in this environment, because of the heavy fishing pressure from local fishermen. Eighty-nine fish taxa (including 65 recognizable species) were recorded from videotapes, photographs, visual observations, fishermen’s catches and ancillary attempts to sample the fish fauna with baited fish traps, gill nets, and hook and line. Although no coelacanth feeding events were seen, seven fish species are known from coelacanth stomach contents, and 64 other fish species in this habitat are considered potential prey of this dominant predator.
- Full Text:
- Date Issued: 2006
- Authors: Heemstra, P C , Hissmann, K , Fricke, H
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7128 , http://hdl.handle.net/10962/d1010638
- Description: Underwater observations of the coelacanth, Latimeria chalumnae Smith, 1939, from a research submersible provided opportunities to study the deep demersal fish fauna at the Comoro Islands. The demersal habitat in depths of 150–400 m at the volcanic island of Ngazidja is low in fish diversity and biomass, compared with the shallow-water coral reef habitat of Ngazidja or the deep demersal habitats of other localities in the Indo-Pacific region. The resident deep demersal fish fauna at Ngazidja is dominated by the coelacanth, an ancient predator that is specially adapted for this low-energy environment. Other large fish predators are scarce in this environment, because of the heavy fishing pressure from local fishermen. Eighty-nine fish taxa (including 65 recognizable species) were recorded from videotapes, photographs, visual observations, fishermen’s catches and ancillary attempts to sample the fish fauna with baited fish traps, gill nets, and hook and line. Although no coelacanth feeding events were seen, seven fish species are known from coelacanth stomach contents, and 64 other fish species in this habitat are considered potential prey of this dominant predator.
- Full Text:
- Date Issued: 2006
A generic database and spatial interface for the application of hydrological and water resource models
- Hughes, Denis A, Forsyth, D A
- Authors: Hughes, Denis A , Forsyth, D A
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7080 , http://hdl.handle.net/10962/d1012333
- Description: The paper discusses a software package that has been designed to enhance the efficiency of applying a range of hydrological and water resource simulation models. The SPATSIM (SPatial and Time Series Information Modeling) system has been developed in Delphi using MapObjects and incorporates a spatial data interface for access to the different types of information commonly associated with water resource analyses. All of the information is stored within database tables (Paradox by default) with generic structures. The structure and components of the system are briefly described and some example applications provided. The discussion identifies some of the criticisms that have been leveled at the software, the approach of the developers to user support and some possible future developments. The conclusions suggest that the development can be considered successful in that it has substantially improved the efficiency of the Institute for Water Research to undertake one of its core functions of hydrological model development and application.
- Full Text:
- Date Issued: 2006
- Authors: Hughes, Denis A , Forsyth, D A
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7080 , http://hdl.handle.net/10962/d1012333
- Description: The paper discusses a software package that has been designed to enhance the efficiency of applying a range of hydrological and water resource simulation models. The SPATSIM (SPatial and Time Series Information Modeling) system has been developed in Delphi using MapObjects and incorporates a spatial data interface for access to the different types of information commonly associated with water resource analyses. All of the information is stored within database tables (Paradox by default) with generic structures. The structure and components of the system are briefly described and some example applications provided. The discussion identifies some of the criticisms that have been leveled at the software, the approach of the developers to user support and some possible future developments. The conclusions suggest that the development can be considered successful in that it has substantially improved the efficiency of the Institute for Water Research to undertake one of its core functions of hydrological model development and application.
- Full Text:
- Date Issued: 2006
African Coelacanth Ecosystem Programme: An overview of the conference contributions
- Ribbink, Anthony J, Roberts, M
- Authors: Ribbink, Anthony J , Roberts, M
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7127 , http://hdl.handle.net/10962/d1010637
- Description: Latimeria chalumnae is the icon for the multidisciplinary, multinational African Coelacanth Ecosystem Programme (ACEP) dedicated to improving the understanding of biological and other processes that support marine life. This article provides an overview of contributions made at a conference hosted by ACEP at the end of 2003. It also reviews significant developments regarding coelacanth conservation which have taken place since the conference. Delegates at the meeting concluded that the integrated regional,ecosystem approach that had been adopted by ACEP should continue. Underwater observation and exploration, however, should be supplemented by more experimental and technical analyses in order to answer longstanding questions related to coelacanths and other organisms.
- Full Text:
- Date Issued: 2006
- Authors: Ribbink, Anthony J , Roberts, M
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7127 , http://hdl.handle.net/10962/d1010637
- Description: Latimeria chalumnae is the icon for the multidisciplinary, multinational African Coelacanth Ecosystem Programme (ACEP) dedicated to improving the understanding of biological and other processes that support marine life. This article provides an overview of contributions made at a conference hosted by ACEP at the end of 2003. It also reviews significant developments regarding coelacanth conservation which have taken place since the conference. Delegates at the meeting concluded that the integrated regional,ecosystem approach that had been adopted by ACEP should continue. Underwater observation and exploration, however, should be supplemented by more experimental and technical analyses in order to answer longstanding questions related to coelacanths and other organisms.
- Full Text:
- Date Issued: 2006
The South African coelacanths — an account of what is known after three submersible expeditions
- Hissmann, K, Fricke, H, Schauer, J
- Authors: Hissmann, K , Fricke, H , Schauer, J
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7131 , http://hdl.handle.net/10962/d1011772
- Description: Using the manned submersible Jago, the habits, distribution and number of coelacanths within all main submarine canyons of the Greater St Lucia Wetland Park were studied during 47 survey dives, with a total bottom time of 166 hours at depths ranging from 46 to 359 m, between 2002 and 2004. Twenty-four individuals were positively identified from three of the canyons, primarily from inside caves at or close to the canyon edges at depths of 96–133 m with water temperatures between 16 and 22.5°C. The population size of coelacanths within the canyons is assumed to be relatively small; coelacanths are resident but not widespread nor abundant within the park.
- Full Text:
- Date Issued: 2006
- Authors: Hissmann, K , Fricke, H , Schauer, J
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7131 , http://hdl.handle.net/10962/d1011772
- Description: Using the manned submersible Jago, the habits, distribution and number of coelacanths within all main submarine canyons of the Greater St Lucia Wetland Park were studied during 47 survey dives, with a total bottom time of 166 hours at depths ranging from 46 to 359 m, between 2002 and 2004. Twenty-four individuals were positively identified from three of the canyons, primarily from inside caves at or close to the canyon edges at depths of 96–133 m with water temperatures between 16 and 22.5°C. The population size of coelacanths within the canyons is assumed to be relatively small; coelacanths are resident but not widespread nor abundant within the park.
- Full Text:
- Date Issued: 2006
Olive Schreiner at 150: some thoughts on re-editing Cronwright's The Reinterment on Buffelskop
- Walters, Paul S, Fogg, W Jeremy M
- Authors: Walters, Paul S , Fogg, W Jeremy M
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6124 , http://hdl.handle.net/10962/d1004708
- Description: [From the introduction]: The original edition of Cronwright’s The Reinterment on Buffelskop (1983) was produced by Guy Butler and Nick Visser to commemorate the centenary of the 1883 publication of The Story of an African Farm. The Butler-Visser text was a photographic reproduction of a typed carbon copy of the first part of Cronwright’s extant diaries plus a special diary he had kept covering in detail the events of the actual reinterment. (The originals are now at the National English Literary Museum [NELM].) Butler included a comprehensive and illuminating introduction to these texts, as well as – under separate soft cover – a set of “Provisional Notes” which draw deeply on his own and his family’s accumulated knowledge of Cradock, its environs and inhabitants. In addition, Butler and Visser included two passages excised by Cronwright from the typescript of his Life of Olive Schreiner: a word picture of Charles Heathcote, and the longer account of “The Nienaber Incident” – pages which deal with the execution of three innocent men at De Aar on 19 March 1901, and Cronwright’s subsequent attempts at legal reparation for them and their families. The substantive text of the Butler-Visser edition is often difficult to read because of the method of reproduction; moreover, because it also reproduces Cronwright’s emendations (in ink) of the typescript, it is frankly uninviting. Thus, when the NELM Council proposed a publication commemorating the 150th anniversary of Olive Schreiner’s birth on 24 March 1855, it seemed appropriate that a second attempt be made to give students of Olive Schreiner’s works easier access to Cronwright’s detailed account of this “bizarre, romantic” episode. Furthermore, from the perspective of text history, the typescript of the Reinterment antedates both Cronwright’s Life and The Letters of Olive Schreiner. Parts of it are clearly Cronwright’s preliminary ‘notes towards’ his Life, and, as Butler hypothesizes, the whole of the Reinterment might have been intended as a separate (and earlier) publication. Finally, the sarcophagus on Buffelskop is one of South Africa’s more noteworthy literary shrines: while the idea of re-editing an account of Olive Schreiner’s reinterment might be thought to be a futile exercise in intellectual recycling, our intention is that both husband and wife should live again through a rediscovery of the thoughts and feelings that led them to this dramatic final resting-place.
- Full Text:
- Date Issued: 2006
- Authors: Walters, Paul S , Fogg, W Jeremy M
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6124 , http://hdl.handle.net/10962/d1004708
- Description: [From the introduction]: The original edition of Cronwright’s The Reinterment on Buffelskop (1983) was produced by Guy Butler and Nick Visser to commemorate the centenary of the 1883 publication of The Story of an African Farm. The Butler-Visser text was a photographic reproduction of a typed carbon copy of the first part of Cronwright’s extant diaries plus a special diary he had kept covering in detail the events of the actual reinterment. (The originals are now at the National English Literary Museum [NELM].) Butler included a comprehensive and illuminating introduction to these texts, as well as – under separate soft cover – a set of “Provisional Notes” which draw deeply on his own and his family’s accumulated knowledge of Cradock, its environs and inhabitants. In addition, Butler and Visser included two passages excised by Cronwright from the typescript of his Life of Olive Schreiner: a word picture of Charles Heathcote, and the longer account of “The Nienaber Incident” – pages which deal with the execution of three innocent men at De Aar on 19 March 1901, and Cronwright’s subsequent attempts at legal reparation for them and their families. The substantive text of the Butler-Visser edition is often difficult to read because of the method of reproduction; moreover, because it also reproduces Cronwright’s emendations (in ink) of the typescript, it is frankly uninviting. Thus, when the NELM Council proposed a publication commemorating the 150th anniversary of Olive Schreiner’s birth on 24 March 1855, it seemed appropriate that a second attempt be made to give students of Olive Schreiner’s works easier access to Cronwright’s detailed account of this “bizarre, romantic” episode. Furthermore, from the perspective of text history, the typescript of the Reinterment antedates both Cronwright’s Life and The Letters of Olive Schreiner. Parts of it are clearly Cronwright’s preliminary ‘notes towards’ his Life, and, as Butler hypothesizes, the whole of the Reinterment might have been intended as a separate (and earlier) publication. Finally, the sarcophagus on Buffelskop is one of South Africa’s more noteworthy literary shrines: while the idea of re-editing an account of Olive Schreiner’s reinterment might be thought to be a futile exercise in intellectual recycling, our intention is that both husband and wife should live again through a rediscovery of the thoughts and feelings that led them to this dramatic final resting-place.
- Full Text:
- Date Issued: 2006
Professor Emeritus Denis William Ewer MBE FRSSAf 1913 - 2009: biographical memoir
- Authors: Hodgson, Alan N
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6884 , http://hdl.handle.net/10962/d1011643
- Description: Denis Ewer went to University College School in London. In 1931 he entered Trinity College, Cambridge (his father had studied mathematics at Trinity) where he read for the Natural Science Tripos, obtaining a B.A. in 1934. In his second year at Cambridge he gained the nickname of 'Jakes' via a literary route (his father's nickname also had literary origins). The word 'ewer' can mean a jug, chamber pot, or jerry, and hence the progress to 'jakes', Elizabethan English for an outside lavatory. It was at Cambridge that he also met the future communist spy, Kim Philby. After graduating, Jakes Ewer moved to the University of Birmingham where he undertook his doctoral studies (graduating PhD in 1940) under H. Munro Fox. World War II, however, temporarily halted any further academic career, and during the war years he was an Experimental Officer for the Army Operational Research Group (Ministry of Supply) achieving the rank of Major. For his work, which included being a Scientific Advisor to the Chief, Air Defence Division, Supreme Headquarters Allied Expeditionary Force, he was awarded the M.B.E. (Member of the British Empire).
- Full Text:
- Date Issued: 2006
- Authors: Hodgson, Alan N
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6884 , http://hdl.handle.net/10962/d1011643
- Description: Denis Ewer went to University College School in London. In 1931 he entered Trinity College, Cambridge (his father had studied mathematics at Trinity) where he read for the Natural Science Tripos, obtaining a B.A. in 1934. In his second year at Cambridge he gained the nickname of 'Jakes' via a literary route (his father's nickname also had literary origins). The word 'ewer' can mean a jug, chamber pot, or jerry, and hence the progress to 'jakes', Elizabethan English for an outside lavatory. It was at Cambridge that he also met the future communist spy, Kim Philby. After graduating, Jakes Ewer moved to the University of Birmingham where he undertook his doctoral studies (graduating PhD in 1940) under H. Munro Fox. World War II, however, temporarily halted any further academic career, and during the war years he was an Experimental Officer for the Army Operational Research Group (Ministry of Supply) achieving the rank of Major. For his work, which included being a Scientific Advisor to the Chief, Air Defence Division, Supreme Headquarters Allied Expeditionary Force, he was awarded the M.B.E. (Member of the British Empire).
- Full Text:
- Date Issued: 2006
Comparison of satellite rainfall data with observations from gauging station networks
- Authors: Hughes, Denis A
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7079 , http://hdl.handle.net/10962/d1009748
- Description: Networks of ground-based hydro-meteorological observations are frequently sparse in developing countries and the situation is not improving. Part of the reason is the lack of resources available in countries which have more pressing economic and social issues. However, these are also the very countries where improved estimates of water resource availability are required. While hydrological models have the potential to provide the necessary information, without adequately accurate climate (rainfall, evaporation, etc.) input information, it is extremely difficult to establish models and generate representative water resource availability information. This paper reports on a preliminary analysis of the potential for using satellite derived rainfall data through a comparison with available gauge data for four basins in the southern Africa region. It is clear that the satellite data cannot be used directly in conjunction with historical gauge data. Specifically, the satellite data do not reflect the strong influences on precipitation of topography in some of the basins. However, the prospects of applying relatively straightforward adjustments are promising and further assessments appear to be justified.
- Full Text:
- Date Issued: 2006
- Authors: Hughes, Denis A
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7079 , http://hdl.handle.net/10962/d1009748
- Description: Networks of ground-based hydro-meteorological observations are frequently sparse in developing countries and the situation is not improving. Part of the reason is the lack of resources available in countries which have more pressing economic and social issues. However, these are also the very countries where improved estimates of water resource availability are required. While hydrological models have the potential to provide the necessary information, without adequately accurate climate (rainfall, evaporation, etc.) input information, it is extremely difficult to establish models and generate representative water resource availability information. This paper reports on a preliminary analysis of the potential for using satellite derived rainfall data through a comparison with available gauge data for four basins in the southern Africa region. It is clear that the satellite data cannot be used directly in conjunction with historical gauge data. Specifically, the satellite data do not reflect the strong influences on precipitation of topography in some of the basins. However, the prospects of applying relatively straightforward adjustments are promising and further assessments appear to be justified.
- Full Text:
- Date Issued: 2006
Lattice-valued continuous convergence is induced by a lattice-valued uniform convergence structure
- Authors: Jäger, Gunter
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6824 , http://hdl.handle.net/10962/d1012332
- Description: We define a stratified L-uniform convergence structure on the set of all continuous mappings from a stratified L-limit space to a stratified L-uniform convergence space. This structure induces L-continuous convergence. This shows that the category of all L-limit-uniformizable spaces is cartesian closed.
- Full Text:
- Date Issued: 2006
- Authors: Jäger, Gunter
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6824 , http://hdl.handle.net/10962/d1012332
- Description: We define a stratified L-uniform convergence structure on the set of all continuous mappings from a stratified L-limit space to a stratified L-uniform convergence space. This structure induces L-continuous convergence. This shows that the category of all L-limit-uniformizable spaces is cartesian closed.
- Full Text:
- Date Issued: 2006
Near-real time foF2 predictions using neural networks
- Oyeyemi, E O, McKinnell, Lee-Anne, Poole, Allon W V
- Authors: Oyeyemi, E O , McKinnell, Lee-Anne , Poole, Allon W V
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6804 , http://hdl.handle.net/10962/d1004167
- Description: This paper describes the use of the neural network (NN) technique for the development of a near-real time global foF2 (NRTNN) empirical model. The data used are hourly daily values of foF2 from 26 worldwide ionospheric stations (based on availability) during the period 1976–1986 for training the NN and between 1977 and 1989 for verifying the prediction accuracy. The training data set includes all periods of quiet and disturbed geomagnetic conditions. Two categories of input parameters were used as inputs to the NN. The first category consists of geophysical parameters that are temporally or spatially related to the training stations. The second category, which is related to the foF2 itself, consists of three recent past observations of foF2 (i.e. real-time foF2 (F0), 2 h (F−2) and 1 h (F−1) prior to F0) from four control stations (i.e. Boulder (40.0°N, 254.7°E), Grahamstown (33.3°S, 26.5°E), Dourbes (50.1°N, 4.6°E) and Port Stanley (51.7°S, 302.2°E). The performance of the NRTNN was verified under both geomagnetically quiet and disturbed conditions with observed data from a few verification stations. A comparison of the root mean square error (RMSE) differences between measured values and the NRTNN predictions with our earlier standard foF2 NN empirical model is also illustrated. The results reveal that NRTNN will predict foF2 in near-real time with about 1 MHz RMSE difference anywhere on the globe, provided real time data is available at the four control stations. From the results it is also evident that in addition to the geophysical information from any geographical location, recent past observations of foF2 from these control stations could be used as inputs to a NN for near-real time foF2 predictions. Results also reveal that there is a temporal correlation between measured foF2 values at different locations.
- Full Text:
- Date Issued: 2006
- Authors: Oyeyemi, E O , McKinnell, Lee-Anne , Poole, Allon W V
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6804 , http://hdl.handle.net/10962/d1004167
- Description: This paper describes the use of the neural network (NN) technique for the development of a near-real time global foF2 (NRTNN) empirical model. The data used are hourly daily values of foF2 from 26 worldwide ionospheric stations (based on availability) during the period 1976–1986 for training the NN and between 1977 and 1989 for verifying the prediction accuracy. The training data set includes all periods of quiet and disturbed geomagnetic conditions. Two categories of input parameters were used as inputs to the NN. The first category consists of geophysical parameters that are temporally or spatially related to the training stations. The second category, which is related to the foF2 itself, consists of three recent past observations of foF2 (i.e. real-time foF2 (F0), 2 h (F−2) and 1 h (F−1) prior to F0) from four control stations (i.e. Boulder (40.0°N, 254.7°E), Grahamstown (33.3°S, 26.5°E), Dourbes (50.1°N, 4.6°E) and Port Stanley (51.7°S, 302.2°E). The performance of the NRTNN was verified under both geomagnetically quiet and disturbed conditions with observed data from a few verification stations. A comparison of the root mean square error (RMSE) differences between measured values and the NRTNN predictions with our earlier standard foF2 NN empirical model is also illustrated. The results reveal that NRTNN will predict foF2 in near-real time with about 1 MHz RMSE difference anywhere on the globe, provided real time data is available at the four control stations. From the results it is also evident that in addition to the geophysical information from any geographical location, recent past observations of foF2 from these control stations could be used as inputs to a NN for near-real time foF2 predictions. Results also reveal that there is a temporal correlation between measured foF2 values at different locations.
- Full Text:
- Date Issued: 2006
Fishes of the deep demersal habitat at Ngazidja (Grand Comoro) Island, Western Indian Ocean
- Heemstra, P C, Hissmann, K, Fricke, H
- Authors: Heemstra, P C , Hissmann, K , Fricke, H
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7158 , http://hdl.handle.net/10962/d1011885
- Description: Underwater observations of the coelacanth, Latimeria chalumnae Smith, 1939, from a research submersible provided opportunities to study the deep demersal fish fauna at the Comoro Islands. The demersal habitat in depths of 150–400 m at the volcanic island of Ngazidja is low in fish diversity and biomass, compared with the shallow-water coral reef habitat of Ngazidja or the deep demersal habitats of other localities in the Indo-Pacific region. The resident deep demersal fish fauna at Ngazidja is dominated by the coelacanth, an ancient predator that is specially adapted for this low-energy environment. Other large fish predators are scarce in this environment, because of the heavy fishing pressure from local fishermen. Eighty-nine fish taxa (including 65 recognizable species) were recorded from videotapes, photographs, visual observations, fishermen’s catches and ancillary attempts to sample the fish fauna with baited fish traps, gill nets, and hook and line. Although no coelacanth feeding events were seen, seven fish species are known from coelacanth stomach contents, and 64 other fish species in this habitat are considered potential prey of this dominant predator.
- Full Text:
- Date Issued: 2006
- Authors: Heemstra, P C , Hissmann, K , Fricke, H
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7158 , http://hdl.handle.net/10962/d1011885
- Description: Underwater observations of the coelacanth, Latimeria chalumnae Smith, 1939, from a research submersible provided opportunities to study the deep demersal fish fauna at the Comoro Islands. The demersal habitat in depths of 150–400 m at the volcanic island of Ngazidja is low in fish diversity and biomass, compared with the shallow-water coral reef habitat of Ngazidja or the deep demersal habitats of other localities in the Indo-Pacific region. The resident deep demersal fish fauna at Ngazidja is dominated by the coelacanth, an ancient predator that is specially adapted for this low-energy environment. Other large fish predators are scarce in this environment, because of the heavy fishing pressure from local fishermen. Eighty-nine fish taxa (including 65 recognizable species) were recorded from videotapes, photographs, visual observations, fishermen’s catches and ancillary attempts to sample the fish fauna with baited fish traps, gill nets, and hook and line. Although no coelacanth feeding events were seen, seven fish species are known from coelacanth stomach contents, and 64 other fish species in this habitat are considered potential prey of this dominant predator.
- Full Text:
- Date Issued: 2006
Interactions of fishes with particular reference to coelacanths in the canyons at Sodwana Bay and the St Lucia Marine Protected Area of South Africa
- Heemstra, Phillip C, Frickle, H, Hissmann, K
- Authors: Heemstra, Phillip C , Frickle, H , Hissmann, K
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7130 , http://hdl.handle.net/10962/d1011771
- Description: The deep demersal fish fauna at depths of 100–400min canyons off the St Lucia Marine Protected Area along the north coast of KwaZulu-Natal is compared with similar fish communities at the Comoro Islands and in the Indo-Pacific region. Fifty-four fish species were seen or photographed from the submersible Jago or by the discovery team of scuba divers in the coelacanth, Latimeria chalumnae, habitat of the canyons off Sodwana Bay. An additional 94 fish species known from depths of 100–200 m along the coast of northern KwaZulu-Natal are likely to occur in the canyon habitat. The fish fauna of the Sodwana canyons shares at least 18 species with the deep demersal fish community off tropical coral reefs of the Indo-Pacific region. Thirty-seven of the Sodwana canyon fishes are also known from the coelacanth habitat in the Comoros.
- Full Text:
- Date Issued: 2006
- Authors: Heemstra, Phillip C , Frickle, H , Hissmann, K
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7130 , http://hdl.handle.net/10962/d1011771
- Description: The deep demersal fish fauna at depths of 100–400min canyons off the St Lucia Marine Protected Area along the north coast of KwaZulu-Natal is compared with similar fish communities at the Comoro Islands and in the Indo-Pacific region. Fifty-four fish species were seen or photographed from the submersible Jago or by the discovery team of scuba divers in the coelacanth, Latimeria chalumnae, habitat of the canyons off Sodwana Bay. An additional 94 fish species known from depths of 100–200 m along the coast of northern KwaZulu-Natal are likely to occur in the canyon habitat. The fish fauna of the Sodwana canyons shares at least 18 species with the deep demersal fish community off tropical coral reefs of the Indo-Pacific region. Thirty-seven of the Sodwana canyon fishes are also known from the coelacanth habitat in the Comoros.
- Full Text:
- Date Issued: 2006
A stability-indicating high performance liquid chromatographic assay for the determination of orlistat in capsules
- Mohammadi, Ali, Haririan, I, Rezanour, I, Ghiasi, L, Walker, Roderick B
- Authors: Mohammadi, Ali , Haririan, I , Rezanour, I , Ghiasi, L , Walker, Roderick B
- Date: 2006
- Language: English
- Type: Article , text
- Identifier: vital:6407 , http://hdl.handle.net/10962/d1006480
- Description: A stability-indicating HPLC method was developed and validated for the quantitative determination of orlistat in capsule dosage forms. An isocratic separation was achieved using a Perfectsil® target ODS-3, 250 mm × 4.6 mm i.d., 5 µm particle size column with a flow rate of 0.7 ml/min and using a UV detector to monitor the eluate at 210 nm. The mobile phase consisted of methanol:acetonitrile:trifluoroacetic acid (82.5:17.5:0.01, v/v/v). The drug was subjected oxidation, hydrolysis, photolysis and heat to apply stress conditions. Complete separation was achieved for the parent compound and all degradation products in an overall analytical run time of approximately 15 min with the parent compound orlistat eluting at approximately 9 min. The method was linear over the concentration range of 0.02–0.75 mg/ml (r = 0.9998) with a limit of detection and quantitation 0.006 and 0.02 mg/ml, respectively. The method has the requisite accuracy, selectivity, sensitivity and precision to assay orlistat in capsules. Degradation products resulting from the stress studies did not interfere with the detection of orlistat and the assay is thus stability-indicating.
- Full Text:
- Date Issued: 2006
- Authors: Mohammadi, Ali , Haririan, I , Rezanour, I , Ghiasi, L , Walker, Roderick B
- Date: 2006
- Language: English
- Type: Article , text
- Identifier: vital:6407 , http://hdl.handle.net/10962/d1006480
- Description: A stability-indicating HPLC method was developed and validated for the quantitative determination of orlistat in capsule dosage forms. An isocratic separation was achieved using a Perfectsil® target ODS-3, 250 mm × 4.6 mm i.d., 5 µm particle size column with a flow rate of 0.7 ml/min and using a UV detector to monitor the eluate at 210 nm. The mobile phase consisted of methanol:acetonitrile:trifluoroacetic acid (82.5:17.5:0.01, v/v/v). The drug was subjected oxidation, hydrolysis, photolysis and heat to apply stress conditions. Complete separation was achieved for the parent compound and all degradation products in an overall analytical run time of approximately 15 min with the parent compound orlistat eluting at approximately 9 min. The method was linear over the concentration range of 0.02–0.75 mg/ml (r = 0.9998) with a limit of detection and quantitation 0.006 and 0.02 mg/ml, respectively. The method has the requisite accuracy, selectivity, sensitivity and precision to assay orlistat in capsules. Degradation products resulting from the stress studies did not interfere with the detection of orlistat and the assay is thus stability-indicating.
- Full Text:
- Date Issued: 2006
Oceanographic environment of the Sodwana Bay coelacanths (Latimeria chalumnae), South Africa
- Roberts, M J, Ribbink, Anthony J, Morris, T
- Authors: Roberts, M J , Ribbink, Anthony J , Morris, T
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7156 , http://hdl.handle.net/10962/d1011883
- Description: Trimix scuba divers discovered coelacanths in Jesser Canyon at a depth of 104 m on the northern KwaZulu-Natal (KZN) coast (Sodwana Bay) in October 2000. The existence of these animals at such a shallow depth and in the swift and powerful Agulhas Current led to a suggestion that this might be an isolated group swept well away from the main population in the Comoros, where they live at depths of 200–350 m with little current. Subsequent observations from three manned submersible surveys and one remotely operated vehicle expedition together with recreational diver observations indicate that the South African population of coelacanths has at least 26 individuals, mostly occupying the depth range of 104–140 m in canyons. Seventeen CTD sections collected during four cruises in 2002 and 2003 indicate the temperature range in this habitat to be similar to that found in the Comoros Islands (that is, 15–22°C cf. 15–19°C in the Comoros). However, a 2.5-month-long time series of hourly data collected by a thermistor array deployed near a known coelacanth cave in Wright Canyon indicated greater variation than anticipated, with temperature changes between 16°C and 24°C occurring in a day. Dissolved oxygen levels in this depth zone were found to range between 3.0 ml l[superscript (–1)] and 4.8 ml l[superscript (–1)] compared to 3.5 ml l[superscript (–1)] in the Comoros. The low oxygen values along this coast are a result of the shallow oxygen minimum, which becomes shallower in the southwest Indian Ocean, particularly in the Agulhas Current, than in tropical latitudes. Current velocities measured using a ship-borne ADCP in the depth range 100–140 m at Sodwana were considerably higher than those measured in the Comoros habitat (20–60 cm s[superscript (–1)] cf. 3–4 cm s[superscript (–1)]) and may be an important factor explaining the coelacanths’ occupation of the canyons found along the northern KZN shelf-break.
- Full Text:
- Date Issued: 2006
- Authors: Roberts, M J , Ribbink, Anthony J , Morris, T
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7156 , http://hdl.handle.net/10962/d1011883
- Description: Trimix scuba divers discovered coelacanths in Jesser Canyon at a depth of 104 m on the northern KwaZulu-Natal (KZN) coast (Sodwana Bay) in October 2000. The existence of these animals at such a shallow depth and in the swift and powerful Agulhas Current led to a suggestion that this might be an isolated group swept well away from the main population in the Comoros, where they live at depths of 200–350 m with little current. Subsequent observations from three manned submersible surveys and one remotely operated vehicle expedition together with recreational diver observations indicate that the South African population of coelacanths has at least 26 individuals, mostly occupying the depth range of 104–140 m in canyons. Seventeen CTD sections collected during four cruises in 2002 and 2003 indicate the temperature range in this habitat to be similar to that found in the Comoros Islands (that is, 15–22°C cf. 15–19°C in the Comoros). However, a 2.5-month-long time series of hourly data collected by a thermistor array deployed near a known coelacanth cave in Wright Canyon indicated greater variation than anticipated, with temperature changes between 16°C and 24°C occurring in a day. Dissolved oxygen levels in this depth zone were found to range between 3.0 ml l[superscript (–1)] and 4.8 ml l[superscript (–1)] compared to 3.5 ml l[superscript (–1)] in the Comoros. The low oxygen values along this coast are a result of the shallow oxygen minimum, which becomes shallower in the southwest Indian Ocean, particularly in the Agulhas Current, than in tropical latitudes. Current velocities measured using a ship-borne ADCP in the depth range 100–140 m at Sodwana were considerably higher than those measured in the Comoros habitat (20–60 cm s[superscript (–1)] cf. 3–4 cm s[superscript (–1)]) and may be an important factor explaining the coelacanths’ occupation of the canyons found along the northern KZN shelf-break.
- Full Text:
- Date Issued: 2006
Language and learning science in South Africa
- Authors: Probyn, Margie J
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7023 , http://hdl.handle.net/10962/d1007204 , http://dx.doi.org/10.2167/le554.0
- Description: South Africa is a multilingual country with 11 official languages. However, English dominates as the language of access and power and although the Language-in- Education Policy (1997) recommends school language policies that will promote additive bilingualism and the use of learners' home languages as languages of learning and teaching, there has been little implementation of these recommendations by schools. This is despite the fact that the majority of learners do not have the necessary English language proficiency to successfully engage with the curriculum and that teachers frequently are obliged to resort to using the learners' home language to mediate understanding. This research investigates the classroom language practices of six Grade 8 science teachers, teaching science through the medium of English where they and their learners share a common home language, Xhosa. Teachers' lessons were videotaped, transcribed and analysed for the opportunities they offered learners for language development and conceptual challenge. The purpose of the research is to better understand the teachers' perceptions and problems and to be able to draw on examples of good practice, to inform teacher training and to develop a coherent bilingual approach for teaching science through the medium of English as an additional language.
- Full Text:
- Date Issued: 2006
- Authors: Probyn, Margie J
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:7023 , http://hdl.handle.net/10962/d1007204 , http://dx.doi.org/10.2167/le554.0
- Description: South Africa is a multilingual country with 11 official languages. However, English dominates as the language of access and power and although the Language-in- Education Policy (1997) recommends school language policies that will promote additive bilingualism and the use of learners' home languages as languages of learning and teaching, there has been little implementation of these recommendations by schools. This is despite the fact that the majority of learners do not have the necessary English language proficiency to successfully engage with the curriculum and that teachers frequently are obliged to resort to using the learners' home language to mediate understanding. This research investigates the classroom language practices of six Grade 8 science teachers, teaching science through the medium of English where they and their learners share a common home language, Xhosa. Teachers' lessons were videotaped, transcribed and analysed for the opportunities they offered learners for language development and conceptual challenge. The purpose of the research is to better understand the teachers' perceptions and problems and to be able to draw on examples of good practice, to inform teacher training and to develop a coherent bilingual approach for teaching science through the medium of English as an additional language.
- Full Text:
- Date Issued: 2006
Application of reverse-flow micellar electrokinetic chromatography for the simultaneous determination of flavonols and terpene trilactones in Ginkgo biloba dosage forms
- Dubber, Mary-Jean, Kanfer, Isadore
- Authors: Dubber, Mary-Jean , Kanfer, Isadore
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6357 , http://hdl.handle.net/10962/d1006049
- Description:
A reverse-flow micellar electrokinetic chromatographic (RF-MEKC) method was developed for the simultaneous qualitative determination of 10 components consisting of the flavonol glycosides, rutin and quercitrin, the flavonol aglycones, isorhamnetin, kaempferol and quercetin, the terpene trilactones, ginkgolides A, B, C and J and the sesquiterpene, bilobalide. This method was used to fingerprint Ginkgo biloba solid oral dosage forms and validated for the quantitation of the marker compounds, rutin and quercetin in some commercial products. In addition to the usual variables, the influence of some essential background electrolyte (BGE) components such as sodium dodecyl sulphate (SDS) and
-cyclodextrin concentrations were investigated. A polyimide fused-silica square capillary column (75 μm I.D. × 360 μm O.D.) with a total length of 60.0 cm and effective length of 45.0 cm was used for the separation. The final BGE consisted of 20 mM phosphoric acid, 40 mM SDS and 12 mM -cyclodextrin (pH 2.2) using reverse polarity with a voltage of −17.5 kV. Samples were injected electrokinetically at −5 kV for 3 s for the qualitative analysis and hydrodynamically at 20 mbar for 0.6 s for the quantitative assay. The total run time was 22 min and the limits of detection were 3.13 μg/ml and 1.88 μg/ml for rutin and quercetin, respectively. Fingerprint profiles of the solid oral dosage forms and the results of the quantitative analysis indicated that there were major discrepancies in the marker content between products and illustrates the value of this method for use as a procedure to assess product quality of commercially available Ginkgo biloba products. - Full Text:
- Date Issued: 2006
- Authors: Dubber, Mary-Jean , Kanfer, Isadore
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6357 , http://hdl.handle.net/10962/d1006049
- Description:
A reverse-flow micellar electrokinetic chromatographic (RF-MEKC) method was developed for the simultaneous qualitative determination of 10 components consisting of the flavonol glycosides, rutin and quercitrin, the flavonol aglycones, isorhamnetin, kaempferol and quercetin, the terpene trilactones, ginkgolides A, B, C and J and the sesquiterpene, bilobalide. This method was used to fingerprint Ginkgo biloba solid oral dosage forms and validated for the quantitation of the marker compounds, rutin and quercetin in some commercial products. In addition to the usual variables, the influence of some essential background electrolyte (BGE) components such as sodium dodecyl sulphate (SDS) and
-cyclodextrin concentrations were investigated. A polyimide fused-silica square capillary column (75 μm I.D. × 360 μm O.D.) with a total length of 60.0 cm and effective length of 45.0 cm was used for the separation. The final BGE consisted of 20 mM phosphoric acid, 40 mM SDS and 12 mM -cyclodextrin (pH 2.2) using reverse polarity with a voltage of −17.5 kV. Samples were injected electrokinetically at −5 kV for 3 s for the qualitative analysis and hydrodynamically at 20 mbar for 0.6 s for the quantitative assay. The total run time was 22 min and the limits of detection were 3.13 μg/ml and 1.88 μg/ml for rutin and quercetin, respectively. Fingerprint profiles of the solid oral dosage forms and the results of the quantitative analysis indicated that there were major discrepancies in the marker content between products and illustrates the value of this method for use as a procedure to assess product quality of commercially available Ginkgo biloba products. - Full Text:
- Date Issued: 2006
Critical media literacy: a design for the future
- Authors: Prinsloo, Jeanne
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6331 , http://hdl.handle.net/10962/d1008476
- Description: [From OPENSPACE Editor Alice Kanengoni's editorial]: Professor Jeanne Prinsloo notes in her article that "In fact, it has been argued that the significance of the media in people’s lives has increased to the extent that it has been described as their primary curriculum, thereby recasting formal education as the secondary curriculum." This therefore requires an incestment in media literacy; people's ability to to understand the world around them, as represented in the media. Thus, Professor Prinsloo argues for critical media literacy, citing the role that the media played in fuelling the genocide in Rwanda, as an illustrative case in point. She states that "While we can not attribute all blame in the Rwandan scenario to the radio use, it is clear that the media mattered." She indicates that "media representations and engagements play a significant role in the way we understand the world, its people and events, and ourselves therein." As such, societies should invest in building a critical citizenry that can read and deconstruct the various ideologies that are often carries in and through the media.
- Full Text:
- Date Issued: 2006
- Authors: Prinsloo, Jeanne
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6331 , http://hdl.handle.net/10962/d1008476
- Description: [From OPENSPACE Editor Alice Kanengoni's editorial]: Professor Jeanne Prinsloo notes in her article that "In fact, it has been argued that the significance of the media in people’s lives has increased to the extent that it has been described as their primary curriculum, thereby recasting formal education as the secondary curriculum." This therefore requires an incestment in media literacy; people's ability to to understand the world around them, as represented in the media. Thus, Professor Prinsloo argues for critical media literacy, citing the role that the media played in fuelling the genocide in Rwanda, as an illustrative case in point. She states that "While we can not attribute all blame in the Rwandan scenario to the radio use, it is clear that the media mattered." She indicates that "media representations and engagements play a significant role in the way we understand the world, its people and events, and ourselves therein." As such, societies should invest in building a critical citizenry that can read and deconstruct the various ideologies that are often carries in and through the media.
- Full Text:
- Date Issued: 2006
Biogeographic and nearshore–offshore trends in isotope ratios of intertidal mussels and their food sources around the coast of southern Africa
- Hill, Jaclyn M, McQuaid, Christopher D, Kaehler, Sven
- Authors: Hill, Jaclyn M , McQuaid, Christopher D , Kaehler, Sven
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6878 , http://hdl.handle.net/10962/d1011633
- Description: There are broad differences in oceanography and primary production around the southern African coast that are likely to give rise to major differences in trophic pathways. Stable isotope ratios provide integrated information on trophic relationships, yet there has been limited research on geographic variation in isotopic composition of marine consumers and their food. In this study, δ13C and δ15N of suspended particulate matter (SPM), intertidal mussels and common macroalgae along the southern African coastline were explored. Nearshore–offshore isotope trends as well as biogeographic and temporal patterns in isotopic ratios of mussel tissue, macroalgae and SPM were investigated at 12 sites along the coast from Namibia to the Mozambique border. SPM exhibited overall trends of nearshore 13C depletion from south-west to north-east along the coastline and from nearshore (0 km) to offshore (10 km) waters, in both cases suggesting a shift from a nearshore signature strongly influenced by macroalgal detritus to one more representative of oceanic phytoplankton. With one exception it was possible, using discriminant analysis, to categorize mussel populations into 4 geographic groups, on the basis of both carbon and nitrogen signatures: the east coast, the south-east coast, the south-west coast and the west coast. Macroalgae showed no consistent biogeographic trends and need to be examined in greater detail to relate nearshore SPM values to living macroalgal signatures. A linear mixing model indicated that mussels along the entire coastline generally demonstrated more than 50% dependence on nearshore carbon and nitrogen, emphasizing the importance of nearshore primary production to intertidal consumers.
- Full Text:
- Date Issued: 2006
- Authors: Hill, Jaclyn M , McQuaid, Christopher D , Kaehler, Sven
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6878 , http://hdl.handle.net/10962/d1011633
- Description: There are broad differences in oceanography and primary production around the southern African coast that are likely to give rise to major differences in trophic pathways. Stable isotope ratios provide integrated information on trophic relationships, yet there has been limited research on geographic variation in isotopic composition of marine consumers and their food. In this study, δ13C and δ15N of suspended particulate matter (SPM), intertidal mussels and common macroalgae along the southern African coastline were explored. Nearshore–offshore isotope trends as well as biogeographic and temporal patterns in isotopic ratios of mussel tissue, macroalgae and SPM were investigated at 12 sites along the coast from Namibia to the Mozambique border. SPM exhibited overall trends of nearshore 13C depletion from south-west to north-east along the coastline and from nearshore (0 km) to offshore (10 km) waters, in both cases suggesting a shift from a nearshore signature strongly influenced by macroalgal detritus to one more representative of oceanic phytoplankton. With one exception it was possible, using discriminant analysis, to categorize mussel populations into 4 geographic groups, on the basis of both carbon and nitrogen signatures: the east coast, the south-east coast, the south-west coast and the west coast. Macroalgae showed no consistent biogeographic trends and need to be examined in greater detail to relate nearshore SPM values to living macroalgal signatures. A linear mixing model indicated that mussels along the entire coastline generally demonstrated more than 50% dependence on nearshore carbon and nitrogen, emphasizing the importance of nearshore primary production to intertidal consumers.
- Full Text:
- Date Issued: 2006
Spatio-temporal variability of larval abundance and settlement of Perna perna: differential delivery of mussels
- Porri, Francesca, McQuaid, Christopher D, Radloff, Sarah E
- Authors: Porri, Francesca , McQuaid, Christopher D , Radloff, Sarah E
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6877 , http://hdl.handle.net/10962/d1011625 , http://dx.doi.org/10.3354/meps315141
- Description: We examined larval availability and settlement of the intertidal mussel Perna perna simultaneously at different spatial and temporal scales using a nested design at 2 sites, 3 km apart on the south coast of South Africa. Each site had 3 locations (300 m apart) where 5 artificial settler collectors were placed about 20 cm apart. Collectors were replaced on temporal scales varying from fortnightly (for 16 mo) to daily (2 series of 15 to 20 d). Each intertidal location was paired with an inshore location (these too were 300 m apart) within 500 m of the shore, where larval availability was measured by 3 vertical plankton hauls collected on the same dates as for settler sampling. There was strong temporal variation in abundances of larvae and settlers, and no correlation (r always < 0.14) was found between the two. Larvae were abundant only at the start of sampling and rare for the rest of the study, while distinct peaks in settler numbers occurred later. No spatial effect was detected for larval availability, while there was strong spatial variation in settlement at the location level. These results indicate that, on scales of 100s of m to km, delivery of larvae from the nearshore water column onto the shore is strongly differential, with some locations consistently receiving more settlers than others. We conclude that, at these sites, the patchiness in settlement observed on scales of 100s of m depends on differential delivery, rather than differential offshore distribution of larvae. We suggest that differential delivery is due to the effect of nearshore bottom topography on local hydrodynamics.
- Full Text:
- Date Issued: 2006
- Authors: Porri, Francesca , McQuaid, Christopher D , Radloff, Sarah E
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6877 , http://hdl.handle.net/10962/d1011625 , http://dx.doi.org/10.3354/meps315141
- Description: We examined larval availability and settlement of the intertidal mussel Perna perna simultaneously at different spatial and temporal scales using a nested design at 2 sites, 3 km apart on the south coast of South Africa. Each site had 3 locations (300 m apart) where 5 artificial settler collectors were placed about 20 cm apart. Collectors were replaced on temporal scales varying from fortnightly (for 16 mo) to daily (2 series of 15 to 20 d). Each intertidal location was paired with an inshore location (these too were 300 m apart) within 500 m of the shore, where larval availability was measured by 3 vertical plankton hauls collected on the same dates as for settler sampling. There was strong temporal variation in abundances of larvae and settlers, and no correlation (r always < 0.14) was found between the two. Larvae were abundant only at the start of sampling and rare for the rest of the study, while distinct peaks in settler numbers occurred later. No spatial effect was detected for larval availability, while there was strong spatial variation in settlement at the location level. These results indicate that, on scales of 100s of m to km, delivery of larvae from the nearshore water column onto the shore is strongly differential, with some locations consistently receiving more settlers than others. We conclude that, at these sites, the patchiness in settlement observed on scales of 100s of m depends on differential delivery, rather than differential offshore distribution of larvae. We suggest that differential delivery is due to the effect of nearshore bottom topography on local hydrodynamics.
- Full Text:
- Date Issued: 2006
The importance of phytoplankton size in mediating trophic interactions within the plankton of a southern African estuary
- Authors: Froneman, P William
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6928 , http://hdl.handle.net/10962/d1011944
- Description: The influence of the phytoplankton size composition in mediating the trophic interactions between the bacteria, phytoplankton, microheterotrophs (<200 μm) and mesozooplankton (>200 μm) was investigated on three occasions in a warm temperate, temporarily open/closed estuary situated along the southern African coastline. Results of the investigation indicated that the microheterotrophs represented the most important consumers of bacteria and chlorophyll (chl)-a <5.0 μm. The low impact of the mesozooplankton on the bacteria and chl-a <5.0 μm during the study appeared to be related to the inability of the larger zooplankton to feed efficiently on small particles. During those periods when total chl-a concentration was dominated by picophytoplankton (<2.0 μm) and microphytoplankton (>20 μm), mesozooplankton were unable to feed efficiently on the chl-a due to feeding constraints. In response to the unfavorable size structure of the phytoplankton assemblages, mesozooplankton appeared to consume the microheterotrophs. The negative impact of the mesozooplankton on the microheterotrophs resulted in a decrease in the impact of these organisms on the bacteria and the chl-a <5.0 μm. This result is consistent with the predator-prey cascades. On the other hand, when the total chl-a was dominated by nanophytoplankton (2–20 μm), mesozooplankton were able to feed directly on the phytoplankton. Results of the study indicate that size structure of the phytoplankton assemblages within estuaries plays an important role in mediating the trophic interactions between the various components of the plankton food web.
- Full Text:
- Date Issued: 2006
- Authors: Froneman, P William
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6928 , http://hdl.handle.net/10962/d1011944
- Description: The influence of the phytoplankton size composition in mediating the trophic interactions between the bacteria, phytoplankton, microheterotrophs (<200 μm) and mesozooplankton (>200 μm) was investigated on three occasions in a warm temperate, temporarily open/closed estuary situated along the southern African coastline. Results of the investigation indicated that the microheterotrophs represented the most important consumers of bacteria and chlorophyll (chl)-a <5.0 μm. The low impact of the mesozooplankton on the bacteria and chl-a <5.0 μm during the study appeared to be related to the inability of the larger zooplankton to feed efficiently on small particles. During those periods when total chl-a concentration was dominated by picophytoplankton (<2.0 μm) and microphytoplankton (>20 μm), mesozooplankton were unable to feed efficiently on the chl-a due to feeding constraints. In response to the unfavorable size structure of the phytoplankton assemblages, mesozooplankton appeared to consume the microheterotrophs. The negative impact of the mesozooplankton on the microheterotrophs resulted in a decrease in the impact of these organisms on the bacteria and the chl-a <5.0 μm. This result is consistent with the predator-prey cascades. On the other hand, when the total chl-a was dominated by nanophytoplankton (2–20 μm), mesozooplankton were able to feed directly on the phytoplankton. Results of the study indicate that size structure of the phytoplankton assemblages within estuaries plays an important role in mediating the trophic interactions between the various components of the plankton food web.
- Full Text:
- Date Issued: 2006