Effective and efficient performance management in local government, with reference to the Cacadu District Municipality
- Authors: Asmah-Andoh, Kwame
- Date: 2012
- Subjects: Performance -- Management , Performance standards -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape , Employees -- Rating of -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:8161 , http://hdl.handle.net/10948/1633 , Performance -- Management , Performance standards -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape , Employees -- Rating of -- South Africa
- Description: This study examined the existing levels of effectiveness and efficiency in local government with the application of performance management systems in the provision of municipal services. The provision of district-wide water services in Cacadu District Municipality in the Province of the Eastern Cape, South Africa is used for particular reference. Local government reforms after 1994 led to the creation of the district municipality (which groups together a number of local municipalities) to drive district-wide services provision, the introduction of systematic services provision standards and performance management as part of management reforms in municipalities. The problem for the research deals with how the Cacadu District Council and the councils of the local municipalities within the district are collaborating in using performance management systems, what effects this could have on programmes and services provision and how communication of performance information would improve service provision. Conceptual and practical difficulties encountered in effective and efficient utilisation and some obstacles that contribute to impeding progress in the use of performance management systems in municipalities were analysed. The qualitative research included a review of documents from the public administration and management literature; discourse analysis of interviews with municipal councilors and appointed officials, community members and provincial managers. The document review included a review of municipal documents that incorporated performance management or described development and use of performance management systems. It also included the legal frameworks and statutory requirements for municipal government and administration. All the responding municipal councils within the Cacadu District Municipality reported using performance management over the past five years yet little empirical evidence explains usage for district-wide programmes and services provision. Research shows that a comprehensive performance management approach to programmes and services has a more effective and efficient impact on service improvement than utilisation of personnnel appraisal (Ammons and Rivenbark, 2005). Despite the expected benefits, personnel performance appraisal is often flawed and the need exists in the district municipal model to develop and utilise performance management systems that validly assess the work performance of personnel (Hindo, 2010). Performance management system utilisation in decision making management is more related to the long-term benefits of effectiveness and efficiency than personnel appraisal for performance rewards and reporting. To overcome and address a situation of managing performance without a performance management system the study proposes a programme performance measurement and management system which incorporates information on management inputs, programme-specific data and citizens' feedback for outcomes and impact of the service. The suggested design for district-wide and specific municipal services provision elicit and provide relevant and appropriate performance information for management, decision-making and accountability to community. The effectiveness of the proposed system is to provide information for decision-making, long-term planning, strategic management and accountability reporting. The proposal is built on the exisiting method and thus efficient in the utilisation of resources. This has implications both for the theory of Public Administration and Management and the practical application of performamce management in public institutions. The study explicity provides a Public Administration perspective on management in a multi-municipal district context with different authorities. The study contributes to the theory of administrative policy and management context of the municipality with special attention to functions for which different authorities are responsible and the role of a performance system for better insught into managing overlapping authority, gaps and duplications. A central purpose of public management research is to theorise and influence practice. The practical utilisation of the proposed method is intended to assist managers and politicians with better understanding of a sustainable performance management system.
- Full Text:
- Date Issued: 2012
- Authors: Asmah-Andoh, Kwame
- Date: 2012
- Subjects: Performance -- Management , Performance standards -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape , Employees -- Rating of -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:8161 , http://hdl.handle.net/10948/1633 , Performance -- Management , Performance standards -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape , Employees -- Rating of -- South Africa
- Description: This study examined the existing levels of effectiveness and efficiency in local government with the application of performance management systems in the provision of municipal services. The provision of district-wide water services in Cacadu District Municipality in the Province of the Eastern Cape, South Africa is used for particular reference. Local government reforms after 1994 led to the creation of the district municipality (which groups together a number of local municipalities) to drive district-wide services provision, the introduction of systematic services provision standards and performance management as part of management reforms in municipalities. The problem for the research deals with how the Cacadu District Council and the councils of the local municipalities within the district are collaborating in using performance management systems, what effects this could have on programmes and services provision and how communication of performance information would improve service provision. Conceptual and practical difficulties encountered in effective and efficient utilisation and some obstacles that contribute to impeding progress in the use of performance management systems in municipalities were analysed. The qualitative research included a review of documents from the public administration and management literature; discourse analysis of interviews with municipal councilors and appointed officials, community members and provincial managers. The document review included a review of municipal documents that incorporated performance management or described development and use of performance management systems. It also included the legal frameworks and statutory requirements for municipal government and administration. All the responding municipal councils within the Cacadu District Municipality reported using performance management over the past five years yet little empirical evidence explains usage for district-wide programmes and services provision. Research shows that a comprehensive performance management approach to programmes and services has a more effective and efficient impact on service improvement than utilisation of personnnel appraisal (Ammons and Rivenbark, 2005). Despite the expected benefits, personnel performance appraisal is often flawed and the need exists in the district municipal model to develop and utilise performance management systems that validly assess the work performance of personnel (Hindo, 2010). Performance management system utilisation in decision making management is more related to the long-term benefits of effectiveness and efficiency than personnel appraisal for performance rewards and reporting. To overcome and address a situation of managing performance without a performance management system the study proposes a programme performance measurement and management system which incorporates information on management inputs, programme-specific data and citizens' feedback for outcomes and impact of the service. The suggested design for district-wide and specific municipal services provision elicit and provide relevant and appropriate performance information for management, decision-making and accountability to community. The effectiveness of the proposed system is to provide information for decision-making, long-term planning, strategic management and accountability reporting. The proposal is built on the exisiting method and thus efficient in the utilisation of resources. This has implications both for the theory of Public Administration and Management and the practical application of performamce management in public institutions. The study explicity provides a Public Administration perspective on management in a multi-municipal district context with different authorities. The study contributes to the theory of administrative policy and management context of the municipality with special attention to functions for which different authorities are responsible and the role of a performance system for better insught into managing overlapping authority, gaps and duplications. A central purpose of public management research is to theorise and influence practice. The practical utilisation of the proposed method is intended to assist managers and politicians with better understanding of a sustainable performance management system.
- Full Text:
- Date Issued: 2012
Design of realistic hybrid marine resource management programs in Oceania
- Aswani, Shankar, Ruddle, Kenneth
- Authors: Aswani, Shankar , Ruddle, Kenneth
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70615 , vital:29681 , https://doi.org/10.2984/67.3.11
- Description: This review article synthesizes the authors' several decades of multidisciplinary natural and social science and applied marine resource management experience in the Asia-Pacific region to examine the strengthening of coastal and marine resource management and conservation using alliances between local communities and external institutions. The objective is to assist the design of resource management and conservation programs that enhance the capacity of coastal communities in Oceania to confront both diminishing marine resources and the effects of climate change by providing guidelines for protecting marine biodiversity and vulnerable ecosystem functions. This article describes a management framework that hybridizes local beliefs and institutions expressed in customary management (CM) with such modern management concepts as marine protected areas (MPAs) and ecosystem-based management (EBM). Hybrid management accommodates the social, political, economic, and cultural contexts of Oceanic communities and, compared with recent or conventional management approaches, can therefore better address fundamental local concerns such as coastal degradation, climate change, sea level rise, weak governance, corruption, limited resources and staff to manage and monitor marine resources, and increasing poverty. Research on the hybridization of management systems demonstrates opportunities to establish context-appropriate EBM and/or other managerial arrangements that include terrestrial and adjacent coastal-marine ecosystems. Formal and informal CM systems are widespread in Oceania and in some parts of Southeast Asia, and if appropriate strategies are employed rapid progress toward hybrid CM-EBM could be enabled.
- Full Text:
- Date Issued: 2012
- Authors: Aswani, Shankar , Ruddle, Kenneth
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70615 , vital:29681 , https://doi.org/10.2984/67.3.11
- Description: This review article synthesizes the authors' several decades of multidisciplinary natural and social science and applied marine resource management experience in the Asia-Pacific region to examine the strengthening of coastal and marine resource management and conservation using alliances between local communities and external institutions. The objective is to assist the design of resource management and conservation programs that enhance the capacity of coastal communities in Oceania to confront both diminishing marine resources and the effects of climate change by providing guidelines for protecting marine biodiversity and vulnerable ecosystem functions. This article describes a management framework that hybridizes local beliefs and institutions expressed in customary management (CM) with such modern management concepts as marine protected areas (MPAs) and ecosystem-based management (EBM). Hybrid management accommodates the social, political, economic, and cultural contexts of Oceanic communities and, compared with recent or conventional management approaches, can therefore better address fundamental local concerns such as coastal degradation, climate change, sea level rise, weak governance, corruption, limited resources and staff to manage and monitor marine resources, and increasing poverty. Research on the hybridization of management systems demonstrates opportunities to establish context-appropriate EBM and/or other managerial arrangements that include terrestrial and adjacent coastal-marine ecosystems. Formal and informal CM systems are widespread in Oceania and in some parts of Southeast Asia, and if appropriate strategies are employed rapid progress toward hybrid CM-EBM could be enabled.
- Full Text:
- Date Issued: 2012
Using co-located radars and instruments to analyse ionespheric events over South Africa
- Authors: Athieno, Racheal
- Date: 2012
- Subjects: Ionosphere -- Research -- South Africa , Space environment -- Research -- South Africa , Meteorology -- Research -- South Africa , Ionosondes -- Research -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5493 , http://hdl.handle.net/10962/d1005279 , Ionosphere -- Research -- South Africa , Space environment -- Research -- South Africa , Meteorology -- Research -- South Africa , Ionosondes -- Research -- South Africa
- Description: Space weather and its effect on technological systems are important for scientific research. Developing an understanding of the behaviour, sources and effects of ionospheric events form a basis for improving space weather prediction. This thesis attempts to use co-located radars and instruments for the analysis of ionospheric events over South Africa. The HF Doppler radar, ionosonde, Global Positioning System (GPS) and GPS ionospheric scintillation monitor (GISTM) receivers are co-located in Hermanus (34.4°S, 19.2°E), one of the observatories for the space science directorate of the South African National Space Agency (SANSA). Data was obtained from these radars and instruments and analysed for ionospheric events. Only the Hermanus station was selected for this analysis, because it is currently the only South African station that hosts all the mentioned radars and instruments. Ionospheric events identified include wave-like structures, Doppler spread, sudden frequency deviations and ionospheric oscillations associated with geomagnetic pulsations. For the purpose of this work, ionospheric events are defined as any unusual structures observed on the received signal and inferred from observations made by the HF Doppler radar. They were identified by visual inspection of the Doppler shift spectrograms. The magnitude and nature of the events vary, depending on their source and were observed by all, some or one instrument. This study suggests that the inclusion of a wider data coverage and more stations in South Africa merit consideration, especially since plans are underway to host a co-located radar network similar to that in Hermanus at at least three additional observatory sites in South Africa. This study lays a foundation for multi-station co-located radar and instrument observation and analysis of ionospheric events which should enhance the accuracy of space weather and HF communication prediction.
- Full Text:
- Date Issued: 2012
- Authors: Athieno, Racheal
- Date: 2012
- Subjects: Ionosphere -- Research -- South Africa , Space environment -- Research -- South Africa , Meteorology -- Research -- South Africa , Ionosondes -- Research -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5493 , http://hdl.handle.net/10962/d1005279 , Ionosphere -- Research -- South Africa , Space environment -- Research -- South Africa , Meteorology -- Research -- South Africa , Ionosondes -- Research -- South Africa
- Description: Space weather and its effect on technological systems are important for scientific research. Developing an understanding of the behaviour, sources and effects of ionospheric events form a basis for improving space weather prediction. This thesis attempts to use co-located radars and instruments for the analysis of ionospheric events over South Africa. The HF Doppler radar, ionosonde, Global Positioning System (GPS) and GPS ionospheric scintillation monitor (GISTM) receivers are co-located in Hermanus (34.4°S, 19.2°E), one of the observatories for the space science directorate of the South African National Space Agency (SANSA). Data was obtained from these radars and instruments and analysed for ionospheric events. Only the Hermanus station was selected for this analysis, because it is currently the only South African station that hosts all the mentioned radars and instruments. Ionospheric events identified include wave-like structures, Doppler spread, sudden frequency deviations and ionospheric oscillations associated with geomagnetic pulsations. For the purpose of this work, ionospheric events are defined as any unusual structures observed on the received signal and inferred from observations made by the HF Doppler radar. They were identified by visual inspection of the Doppler shift spectrograms. The magnitude and nature of the events vary, depending on their source and were observed by all, some or one instrument. This study suggests that the inclusion of a wider data coverage and more stations in South Africa merit consideration, especially since plans are underway to host a co-located radar network similar to that in Hermanus at at least three additional observatory sites in South Africa. This study lays a foundation for multi-station co-located radar and instrument observation and analysis of ionospheric events which should enhance the accuracy of space weather and HF communication prediction.
- Full Text:
- Date Issued: 2012
An investigation into the relationship between leadership and cognitive styles of supervisory employees in the automotive industry
- Authors: Attwell, Terry-Anne
- Date: 2012
- Subjects: Supervisors, Industrial , Cognitive styles , Leadership , Automobile industry and trade
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9403 , http://hdl.handle.net/10948/d1009320 , Supervisors, Industrial , Cognitive styles , Leadership , Automobile industry and trade
- Description: Human attributes that constitute a good leader in terms of leadership qualities and thinking styles are somewhat limited. The latter situation makes it difficult to employ the right person with the right leadership qualities in the continuously changing world of work (Lussier & Achua, 2000). The researcher investigated the relationship between cognitive styles and leadership styles of individuals who are employed in the automotive industry and in a supervisory position. A quantitative research methodology was employed for the study of (n= 115) using the Cognitive-Style Indicator (COSI) developed by Cools and van den Broeck (2007) and the Leadership-style questionnaire developed by Clark (2007). Leadership styles have been researched throughout the world, but a dearth of research specifically pertaining to cognitive styles was rather limiting in the context of the research that was undertaken. On the one hand, leadership focuses on three main dimensions, namely: Authoritarian, Participative and Delegative Leadership Styles. According to Clark (2007), the above three dimensions are the core styles that are used within the workplace. On the other hand, a three-dimensional cognitive style model, as proposed by Cools and Van den Broeck (2007) incorporates three dimensions with specific characteristics pertaining to each style. These three dimensions were labelled as: Knowing (K), Planning (P), and Creating (C) styles, which were utilised to find a significant relationship between the various leadership styles. Significant relationships were found between the Cognitive-Planning style and the Participative Leadership style, the Delegative Leadership style and the Knowing-Cognitive style, the Creative-Cognitive style and the Delegative Leadership style, and the Knowing-and-Planning Cognitive style. Similarities were also found between the Coloured and African groups, as the Delegative style is relevant to both the Coloured and African groups, while the participative style is more prominent in the White racial group. No significant correlations were produced for the Asian group, however. Organisations are rapidly changing and adapting to various types of change; and it is essential for all employees – and not only those within a leadership position – but it is imperative that leaders should not only understand and know their cognitive and leadership style, but also of those individuals who are reporting to them.
- Full Text:
- Date Issued: 2012
- Authors: Attwell, Terry-Anne
- Date: 2012
- Subjects: Supervisors, Industrial , Cognitive styles , Leadership , Automobile industry and trade
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9403 , http://hdl.handle.net/10948/d1009320 , Supervisors, Industrial , Cognitive styles , Leadership , Automobile industry and trade
- Description: Human attributes that constitute a good leader in terms of leadership qualities and thinking styles are somewhat limited. The latter situation makes it difficult to employ the right person with the right leadership qualities in the continuously changing world of work (Lussier & Achua, 2000). The researcher investigated the relationship between cognitive styles and leadership styles of individuals who are employed in the automotive industry and in a supervisory position. A quantitative research methodology was employed for the study of (n= 115) using the Cognitive-Style Indicator (COSI) developed by Cools and van den Broeck (2007) and the Leadership-style questionnaire developed by Clark (2007). Leadership styles have been researched throughout the world, but a dearth of research specifically pertaining to cognitive styles was rather limiting in the context of the research that was undertaken. On the one hand, leadership focuses on three main dimensions, namely: Authoritarian, Participative and Delegative Leadership Styles. According to Clark (2007), the above three dimensions are the core styles that are used within the workplace. On the other hand, a three-dimensional cognitive style model, as proposed by Cools and Van den Broeck (2007) incorporates three dimensions with specific characteristics pertaining to each style. These three dimensions were labelled as: Knowing (K), Planning (P), and Creating (C) styles, which were utilised to find a significant relationship between the various leadership styles. Significant relationships were found between the Cognitive-Planning style and the Participative Leadership style, the Delegative Leadership style and the Knowing-Cognitive style, the Creative-Cognitive style and the Delegative Leadership style, and the Knowing-and-Planning Cognitive style. Similarities were also found between the Coloured and African groups, as the Delegative style is relevant to both the Coloured and African groups, while the participative style is more prominent in the White racial group. No significant correlations were produced for the Asian group, however. Organisations are rapidly changing and adapting to various types of change; and it is essential for all employees – and not only those within a leadership position – but it is imperative that leaders should not only understand and know their cognitive and leadership style, but also of those individuals who are reporting to them.
- Full Text:
- Date Issued: 2012
Factors affecting the retention of employees in auditing firms
- Authors: Axon, Kerry
- Date: 2012
- Subjects: Employee retention -- South Africa -- Port Elizabeth , Labor turnover -- South Africa -- Port Elizabeth , Auditing -- South Africa , Job satisfaction -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9408 , http://hdl.handle.net/10948/d1015728
- Description: The twenty first century has identified knowledge, as opposed to labour, raw materials or capital, as the key resource required by firms. This has created a shift of ownership in relationships between employees and employers since employees own the tools of production through the knowledge they hold (Kinnear & Sutherland, 2000). The employment relationship is undergoing fundamental changes due to international competition, de-regularisation and globalisation which have major implications for attraction, motivation and retention of talented employees (De Vos & Meganck, 2009). Organisations face great challenges and intense competition with almost all strategies being easily replicable by competitors. This has led organisations to begin realising that people are in fact the only real differentiator that can gain the organisation competitive advantage (Munsamy & Bosch Venter, 2009). Turnover of employees costs South Africa millions of rands per annum through decreased productivity, increased accidents and quality problems. Specifically, loss of knowledge workers are identified through costs of hiring and training new employees, loss of institutional knowledge, lower office morale, loss of talent and customer dissatisfaction. It is therefore essential to understand the reasons why employees leave organisations in order to discover how to retain them (Mendes & Stander, 2011; Gaylard, Sutherland & Viedge, 2005). Employee turnover can have several negative consequences. It can be difficult to replace the departed employees and the cost of replacing employees can be exhaustive. Remaining employees can be left feeling demoralised from the loss of valued co-workers and work patterns can be disrupted until replacements are found (Newstrom and Davis, 1997). Bilal, Zia-ur-Rehman, and Raza, (2010) add to this list of negative consequences of turnover as turnover can increase recruitment and training costs, loss of productivity as projects lose continuity, interruption of key activities, increase in mistakes made, or even hiring the wrong person for the position.
- Full Text:
- Date Issued: 2012
- Authors: Axon, Kerry
- Date: 2012
- Subjects: Employee retention -- South Africa -- Port Elizabeth , Labor turnover -- South Africa -- Port Elizabeth , Auditing -- South Africa , Job satisfaction -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9408 , http://hdl.handle.net/10948/d1015728
- Description: The twenty first century has identified knowledge, as opposed to labour, raw materials or capital, as the key resource required by firms. This has created a shift of ownership in relationships between employees and employers since employees own the tools of production through the knowledge they hold (Kinnear & Sutherland, 2000). The employment relationship is undergoing fundamental changes due to international competition, de-regularisation and globalisation which have major implications for attraction, motivation and retention of talented employees (De Vos & Meganck, 2009). Organisations face great challenges and intense competition with almost all strategies being easily replicable by competitors. This has led organisations to begin realising that people are in fact the only real differentiator that can gain the organisation competitive advantage (Munsamy & Bosch Venter, 2009). Turnover of employees costs South Africa millions of rands per annum through decreased productivity, increased accidents and quality problems. Specifically, loss of knowledge workers are identified through costs of hiring and training new employees, loss of institutional knowledge, lower office morale, loss of talent and customer dissatisfaction. It is therefore essential to understand the reasons why employees leave organisations in order to discover how to retain them (Mendes & Stander, 2011; Gaylard, Sutherland & Viedge, 2005). Employee turnover can have several negative consequences. It can be difficult to replace the departed employees and the cost of replacing employees can be exhaustive. Remaining employees can be left feeling demoralised from the loss of valued co-workers and work patterns can be disrupted until replacements are found (Newstrom and Davis, 1997). Bilal, Zia-ur-Rehman, and Raza, (2010) add to this list of negative consequences of turnover as turnover can increase recruitment and training costs, loss of productivity as projects lose continuity, interruption of key activities, increase in mistakes made, or even hiring the wrong person for the position.
- Full Text:
- Date Issued: 2012
In vitro cytotoxic effects of selected Nigerian medicinal plant extracts on cancer cell lines
- Authors: Baatjies, Lucinda
- Date: 2012
- Subjects: Cancer -- Treatment , Cancer cells , Medicinal plants , Plant extracts , Traditional medicine , Public health
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10316 , http://hdl.handle.net/10948/d1008191 , Cancer -- Treatment , Cancer cells , Medicinal plants , Plant extracts , Traditional medicine , Public health
- Description: Cancer is a disease that imposes a heavy burden on public health and poses a challenge to science. The World Health Organization estimates that 80 percent of people in developing countries of the world rely on traditional medicine for their primary health needs, and about 85 percent of traditional medicine involves the use of plant extracts. This is particularly true in Africa where a large percentage of the population depends upon medicinal plants for health care. Therefore, detailed screening and evaluation of bioactive substances for chemotherapeutic purposes of African plants are urgently warranted. Furthermore, this will serve to validate the efficacy and safety of African traditional medicine. The current study investigated the in vitro cytotoxic effects of 17 ethanolic extracts of the following 16 plants used in traditional anticancer medicine in Nigeria: Sapium ellipticum leaves, Sapium ellipticum stembark, Combretum paniculatum, Celosia trigyna, Pupalia lappacea, Justica extensa, Hedranthera barteri leaves, Alternanthera sessilis, Ethulia conyzoides leaves, Lannea nigritana stembark, Combretum zenkeri root, Combretum molle leaves, Adenanthera parvoniana, Lannea acida, Cyathula achyranthoides, Drymaria cordata, Cyathula prostrata, against HeLa cancer cells. Five of the most promising extracts (Sapium ellipticum leaves, Combretum paniculatum, Celosia trigyna, Drymaria cordata, Cyathula prostrata) were selected for further screening against HT29 and MCF-7 cancer cells. Of the five, the first two were investigated further based on their activities in the screening phase. The S. ellipticum leaf extract yielded IC50 values of 88.60 ± 0.03 and 93.03 ± 0.03 μg/ml against HeLa and MCF-7, respectively. The toxicity was also evaluated on normal cells and an IC50 of 77.66 μg/ml was obtained for peripheral blood mononuclear cells (PBMCs). The IC50 values for proliferating and confluent Chang liver cells were both >125 μg/ml. These results suggest that the extract may be selective for specific cell types. Bio-assay guided fractionation of the S. ellipticum ethanolic extract yielded two active fractions; chloroform and ethyl acetate. Two compounds isolated from the chloroform extract were screened against the three cancer cell lines and found to be inactive. Three compounds were isolated from the ethyl acetate fraction and revealed IC50 values < 62.5 and < 31 μg/ml against MCF-7. Unfortunately these two compounds soon lost activity before any further work could be done on them and work was continued with the crude extract.
- Full Text:
- Date Issued: 2012
- Authors: Baatjies, Lucinda
- Date: 2012
- Subjects: Cancer -- Treatment , Cancer cells , Medicinal plants , Plant extracts , Traditional medicine , Public health
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10316 , http://hdl.handle.net/10948/d1008191 , Cancer -- Treatment , Cancer cells , Medicinal plants , Plant extracts , Traditional medicine , Public health
- Description: Cancer is a disease that imposes a heavy burden on public health and poses a challenge to science. The World Health Organization estimates that 80 percent of people in developing countries of the world rely on traditional medicine for their primary health needs, and about 85 percent of traditional medicine involves the use of plant extracts. This is particularly true in Africa where a large percentage of the population depends upon medicinal plants for health care. Therefore, detailed screening and evaluation of bioactive substances for chemotherapeutic purposes of African plants are urgently warranted. Furthermore, this will serve to validate the efficacy and safety of African traditional medicine. The current study investigated the in vitro cytotoxic effects of 17 ethanolic extracts of the following 16 plants used in traditional anticancer medicine in Nigeria: Sapium ellipticum leaves, Sapium ellipticum stembark, Combretum paniculatum, Celosia trigyna, Pupalia lappacea, Justica extensa, Hedranthera barteri leaves, Alternanthera sessilis, Ethulia conyzoides leaves, Lannea nigritana stembark, Combretum zenkeri root, Combretum molle leaves, Adenanthera parvoniana, Lannea acida, Cyathula achyranthoides, Drymaria cordata, Cyathula prostrata, against HeLa cancer cells. Five of the most promising extracts (Sapium ellipticum leaves, Combretum paniculatum, Celosia trigyna, Drymaria cordata, Cyathula prostrata) were selected for further screening against HT29 and MCF-7 cancer cells. Of the five, the first two were investigated further based on their activities in the screening phase. The S. ellipticum leaf extract yielded IC50 values of 88.60 ± 0.03 and 93.03 ± 0.03 μg/ml against HeLa and MCF-7, respectively. The toxicity was also evaluated on normal cells and an IC50 of 77.66 μg/ml was obtained for peripheral blood mononuclear cells (PBMCs). The IC50 values for proliferating and confluent Chang liver cells were both >125 μg/ml. These results suggest that the extract may be selective for specific cell types. Bio-assay guided fractionation of the S. ellipticum ethanolic extract yielded two active fractions; chloroform and ethyl acetate. Two compounds isolated from the chloroform extract were screened against the three cancer cell lines and found to be inactive. Three compounds were isolated from the ethyl acetate fraction and revealed IC50 values < 62.5 and < 31 μg/ml against MCF-7. Unfortunately these two compounds soon lost activity before any further work could be done on them and work was continued with the crude extract.
- Full Text:
- Date Issued: 2012
An evaluation of changes in capital investment by automotive companies in preparation for the Automotive Production and Development Programme (APDP)
- Authors: Bacela, Bandile Sakhekile
- Date: 2012
- Subjects: Automobile industry and trade -- South Africa , Capital investments -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8797 , http://hdl.handle.net/10948/d1016075
- Description: To thrive, developing countries depend on high levels of protection being given to key industries such as manufacturing; specifically the automotive and textile industries. South Africa, as a developing country and especially under the emergence of globalisation, has followed suit in terms of developing policies and structures to protect certain critical industries. During an era (1980 to 1989) of high political instability, South Africa experienced isolation from the rest of the world, which resulted in declines in industrial revenues as well as the country’s automotive industry undergoing a stage of perilous stagnation. It was through a protection regime that the automotive industry realised growth, a regime which started slowly in 1989 and accelerated in 1995 with the introduction of the Motor Industry Development Programme (MIDP) (Black, 2001). Through this regime the South African government sought to integrate the South African automotive industry into the global market by improving the competitiveness of this industry (The DTI, 2010). This led to the automotive industry becoming one of the most successful export sectors in South African manufacturing and a large net consumer of foreign currency, totalling R20 billion and R10 billion in imports and exports respectively by 1998 (Damoense and Simon, 2004). Reviews of the government legislation called the MIDP were held in year 1999 and 2002 and in 2008, a successor to the MIDP was named, the Automotive Production Development Programme (APDP) and is set to commence in year 2013 until 2020. Unlike its predecessor, the APDP policy promises to bring greater and more inclusive benefits to the automotive industry as a whole, provided organisations have prepared well to receive it. This study investigated whether organisations have prepared for the upcoming 2013 - 2020 APDP, with specific reference to capital investment in equipment. It determined whether automotive organisations have spent and are going to spend resources in securing equipment and technology in preparation for the introduction of the APDP.
- Full Text:
- Date Issued: 2012
- Authors: Bacela, Bandile Sakhekile
- Date: 2012
- Subjects: Automobile industry and trade -- South Africa , Capital investments -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8797 , http://hdl.handle.net/10948/d1016075
- Description: To thrive, developing countries depend on high levels of protection being given to key industries such as manufacturing; specifically the automotive and textile industries. South Africa, as a developing country and especially under the emergence of globalisation, has followed suit in terms of developing policies and structures to protect certain critical industries. During an era (1980 to 1989) of high political instability, South Africa experienced isolation from the rest of the world, which resulted in declines in industrial revenues as well as the country’s automotive industry undergoing a stage of perilous stagnation. It was through a protection regime that the automotive industry realised growth, a regime which started slowly in 1989 and accelerated in 1995 with the introduction of the Motor Industry Development Programme (MIDP) (Black, 2001). Through this regime the South African government sought to integrate the South African automotive industry into the global market by improving the competitiveness of this industry (The DTI, 2010). This led to the automotive industry becoming one of the most successful export sectors in South African manufacturing and a large net consumer of foreign currency, totalling R20 billion and R10 billion in imports and exports respectively by 1998 (Damoense and Simon, 2004). Reviews of the government legislation called the MIDP were held in year 1999 and 2002 and in 2008, a successor to the MIDP was named, the Automotive Production Development Programme (APDP) and is set to commence in year 2013 until 2020. Unlike its predecessor, the APDP policy promises to bring greater and more inclusive benefits to the automotive industry as a whole, provided organisations have prepared well to receive it. This study investigated whether organisations have prepared for the upcoming 2013 - 2020 APDP, with specific reference to capital investment in equipment. It determined whether automotive organisations have spent and are going to spend resources in securing equipment and technology in preparation for the introduction of the APDP.
- Full Text:
- Date Issued: 2012
Welcome Address of the Vice‐Chancellor of Rhodes University, Dr Saleem Badat, to First‐Year students
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7592 , http://hdl.handle.net/10962/d1006583
- Description: From introduction: Our first purpose is to produce knowledge, so that we can better understand our natural and social worlds and also enrich our scientific and cultural heritage. The second purpose of a university is to disseminate knowledge and to develop critical and creative minds. Our goals, yours and ours, must be for you to think imaginatively, ‘effectively and critically;’ to ‘achieve depth in some field of knowledge;’ to appreciate how we ‘gain knowledge and understanding of the universe, of society, and of ourselves;’ to have ‘a broad knowledge of other cultures and other times;’ to critique ideas and views and construct alternatives, and to communicate cogently, orally and in writing. Our final purpose as a university is to undertake community engagement, whether this is as part of academic courses or your voluntary participation in community projects organized by our Community Engagement Office.
- Full Text:
- Date Issued: 2012
Welcome Address of the Vice‐Chancellor of Rhodes University, Dr Saleem Badat, to First‐Year students
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7592 , http://hdl.handle.net/10962/d1006583
- Description: From introduction: Our first purpose is to produce knowledge, so that we can better understand our natural and social worlds and also enrich our scientific and cultural heritage. The second purpose of a university is to disseminate knowledge and to develop critical and creative minds. Our goals, yours and ours, must be for you to think imaginatively, ‘effectively and critically;’ to ‘achieve depth in some field of knowledge;’ to appreciate how we ‘gain knowledge and understanding of the universe, of society, and of ourselves;’ to have ‘a broad knowledge of other cultures and other times;’ to critique ideas and views and construct alternatives, and to communicate cogently, orally and in writing. Our final purpose as a university is to undertake community engagement, whether this is as part of academic courses or your voluntary participation in community projects organized by our Community Engagement Office.
- Full Text:
- Date Issued: 2012
Remembering Jakes - Chancellor, our chancellor
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7584 , http://hdl.handle.net/10962/d1006574
- Description: From introduction: Gerwel was an exceptional, courageous, gifted and pioneering South African intellectual, scholar, leader and citizen. He had a profound commitment to creating a just and humane society. Through a long and distinguished association with the higher education sector, as an academic, dean, vice-chancellor, chairperson of the Committee of University Principals in the early 1990s, chancellor, and chairperson of the Mandela Rhodes Foundation, Gerwel was an outstanding champion of higher education. As chancellor, he challenged Rhodes to become socially conscious and think critically and imaginatively about access, equity and transformation, and about its role in socioeconomic development issues in South Africa, especially in the Eastern Cape.
- Full Text:
- Date Issued: 2012
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7584 , http://hdl.handle.net/10962/d1006574
- Description: From introduction: Gerwel was an exceptional, courageous, gifted and pioneering South African intellectual, scholar, leader and citizen. He had a profound commitment to creating a just and humane society. Through a long and distinguished association with the higher education sector, as an academic, dean, vice-chancellor, chairperson of the Committee of University Principals in the early 1990s, chancellor, and chairperson of the Mandela Rhodes Foundation, Gerwel was an outstanding champion of higher education. As chancellor, he challenged Rhodes to become socially conscious and think critically and imaginatively about access, equity and transformation, and about its role in socioeconomic development issues in South Africa, especially in the Eastern Cape.
- Full Text:
- Date Issued: 2012
Rhodes University 2012 Graduation Ceremonies Address
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7588 , http://hdl.handle.net/10962/d1006579
- Description: From introduction: We take pride in our striving to ensure that we are an environment in which knowledge, understanding and the intellect can flower; in being a leading postgraduate and research university that takes undergraduate studies seriously; in enjoying among the best pass and graduation rates in South Africa; in our increasing engagement with local communities; in the pursuit of equity and excellence, and in being a cosmopolitan institution with students from some 56 countries.
- Full Text:
- Date Issued: 2012
- Authors: Badat, Saleem
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:7588 , http://hdl.handle.net/10962/d1006579
- Description: From introduction: We take pride in our striving to ensure that we are an environment in which knowledge, understanding and the intellect can flower; in being a leading postgraduate and research university that takes undergraduate studies seriously; in enjoying among the best pass and graduation rates in South Africa; in our increasing engagement with local communities; in the pursuit of equity and excellence, and in being a cosmopolitan institution with students from some 56 countries.
- Full Text:
- Date Issued: 2012
The allelopathic potential of Arctotis Arctotoides (L.f.) O. Hoffm on some vegetables
- Authors: Badmus, Abimbola Adesile
- Date: 2012
- Subjects: Allelopathy , Allelopathic agents , Vegetables -- Microbiology , Enzyme inhibitors
- Language: English
- Type: Thesis , Doctoral , PhD (Botany)
- Identifier: vital:11306 , http://hdl.handle.net/10353/454 , Allelopathy , Allelopathic agents , Vegetables -- Microbiology , Enzyme inhibitors
- Description: Laboratory and greenhouse experiments were conducted to evaluate the allelopathic effects of the extracts and residue Arctotis arctotoides (L.f.) O. Hoffm on selected vegetable crops. The study aimed to address the following specific objectives to (i) examine the ultra structures of the leaf of A. arctotoides using the Scanning Electron Microscope (SEM), (ii) carry out comprehensive qualitative and quantitative phytochemical analysis of the root and shoot materials of the plant, (iii) investigate the allelopathic activities of the root and shoot aqueous extracts of A. arctotoides at concentrations of 10, 8, 6, 4 and 2 mg/ml on germination, radicle and plumule growth of cabbage, carrot, tomato and spinach, (iv) evaluate the inhibitory effects of the dried shoot residue of the plant at 10, 20 and 40 g kg-3 of soil (treatments B, C and D) and the control (treatment A) on the morphology, growth and chlorophyll pigment content of tomato and cabbage transplants at 1, 2, 3 and 4 weeks after transplanting and (v) assess the effects of the dried shoot residue of A. arctotoides on the yield, nutrient uptake by the leaves of tomato and cabbage at 4 and 12 weeks after transplanting. Finally, to analyze the residual mineral content of the soils with tomato and cabbage transplants at 12 weeks after transplanting. The the SEM revealed that anisocytic stomata and glandular trichomes (GTs) were numerous on the abaxial than the adaxial surfaces of A. arctotoides. The non glandular trichomes (NGTs) were also present on both surfaces but lesser on the abaxial. Morphologically, the GTs were peltate, uniseriate and globular head while the NGTs were cylindrical and filamentous with variable number of cells at the basal portion. The energy dispersive X-ray spectroscopy of some crystals showed that Na+ Mg2+ and Ca2+ were the major constituents of the crystal deposit found around the GTs and stomata. The results of the phytochemical composition of the root and shoot extracts of A. arctotoides confirmed the occurrence of alkaloids, flavonoids, phenolics, saponnins, tannins and triterpenes as the common constituents. In addition, cardiac glycosides and steroids were also detected in the shoot of the A. arctotoides. Quantitative estimation of the chemical constituents of the crude extracts further revealed that the alkaloid content in the root higher (0.97 percent) than the shoot (0.64 percent). The quantity of flavonoids detected in the shoot (1.02 percent) was more than that observed in the root (0.35 percent). Others (phenolics and tannins) were marginal in the two plant parts. The results of the inhibitory effects of the root and shoot aqueous extract at the varying concentrations showed that root extract at 10 mg/ml considerably reduced the germination of cabbage, carrot, tomato and spinach seeds by 84.0, 83.2, 72.8 and 37.4 percent respectively. Incubation of the shoot extract at the same concentration resulted in 100 percent inhibition of cabbage and carrot seed germination whereas those of tomato and spinach were suppressed by 91.5 and 61.2 percent respectively. The two extracts at the varying concentrations also had a significant reduction on the radicle and plumule growth of the four vegetables. Addition of the shoot residue to the soil showed massive chlorosis, necrotic lesions and wilting of tomato and cabbage leaves under treatments C and D at 2 weeks after transplanting. The number of leaves, leaf area, dry shoot and root weight of the two vegetables grown in the amended soils were also drastically reduced. The inhibition percentages due to the addition of the three concentrations of A. arctotoides dried shoot residue on the dry shoot weight at 4 weeks after transplanting were 38.6, 45.5 and 70.3. for tomato and 57.5, 73.3 and 87.5 percent for cabbage. Similarly, the declines in the dry root weight of 61.3, 82.9.4 and 83.4 percent for tomato as well as 53.1, 54.7 and 67.2 percent for cabbages were recorded for the two vegetables under treatment B, C and D during the period. The results further showed that the dry fruit yield and shoot weight of tomato under the treatments B, C and D decreased with increase in shoot residue concentrations of A. arctotoides. Relative to treatment A, no significant differences were recorded in the dry head weight of cabbage under the residue treated groups. The reductions in the fruit yield and fresh head weight caused by treatments C and D were 37.2 and 84.8 percent for tomato and 30.9 and 72.4 percent for cabbage. The findings on the mineral contents in the leaves of the two vegetables revealed significant differences in the uptake of N, Mg, Na, Cu and Fe by tomato leaves. The concentrations of N, K, Na and Zn in cabbage leaves also differed. However, the P content was relatively constant in the leaves of the two vegetables at 4 and 12 weeks after transplanting. At 12 weeks after transplanting, the Fe content in soils with tomato and cabbage treatments C and D was greatly enhanced in comparison with the other nutrients. The residual N, P and Zn detected in soils planted to cabbage were similarly equal among all the groups including the control. Thus, under the greenhouse experiment, Arctotis arctotoides (L.f) O. Hoffm has been shown to contain some phytotoxic chemical compounds in its root and shoot materials. The compounds either singly or collectively have demonstrated some inhibitory potentials on the germination, growth and yields of cabbage, carrot, tomato and spinach evaluated in this study.
- Full Text:
- Date Issued: 2012
- Authors: Badmus, Abimbola Adesile
- Date: 2012
- Subjects: Allelopathy , Allelopathic agents , Vegetables -- Microbiology , Enzyme inhibitors
- Language: English
- Type: Thesis , Doctoral , PhD (Botany)
- Identifier: vital:11306 , http://hdl.handle.net/10353/454 , Allelopathy , Allelopathic agents , Vegetables -- Microbiology , Enzyme inhibitors
- Description: Laboratory and greenhouse experiments were conducted to evaluate the allelopathic effects of the extracts and residue Arctotis arctotoides (L.f.) O. Hoffm on selected vegetable crops. The study aimed to address the following specific objectives to (i) examine the ultra structures of the leaf of A. arctotoides using the Scanning Electron Microscope (SEM), (ii) carry out comprehensive qualitative and quantitative phytochemical analysis of the root and shoot materials of the plant, (iii) investigate the allelopathic activities of the root and shoot aqueous extracts of A. arctotoides at concentrations of 10, 8, 6, 4 and 2 mg/ml on germination, radicle and plumule growth of cabbage, carrot, tomato and spinach, (iv) evaluate the inhibitory effects of the dried shoot residue of the plant at 10, 20 and 40 g kg-3 of soil (treatments B, C and D) and the control (treatment A) on the morphology, growth and chlorophyll pigment content of tomato and cabbage transplants at 1, 2, 3 and 4 weeks after transplanting and (v) assess the effects of the dried shoot residue of A. arctotoides on the yield, nutrient uptake by the leaves of tomato and cabbage at 4 and 12 weeks after transplanting. Finally, to analyze the residual mineral content of the soils with tomato and cabbage transplants at 12 weeks after transplanting. The the SEM revealed that anisocytic stomata and glandular trichomes (GTs) were numerous on the abaxial than the adaxial surfaces of A. arctotoides. The non glandular trichomes (NGTs) were also present on both surfaces but lesser on the abaxial. Morphologically, the GTs were peltate, uniseriate and globular head while the NGTs were cylindrical and filamentous with variable number of cells at the basal portion. The energy dispersive X-ray spectroscopy of some crystals showed that Na+ Mg2+ and Ca2+ were the major constituents of the crystal deposit found around the GTs and stomata. The results of the phytochemical composition of the root and shoot extracts of A. arctotoides confirmed the occurrence of alkaloids, flavonoids, phenolics, saponnins, tannins and triterpenes as the common constituents. In addition, cardiac glycosides and steroids were also detected in the shoot of the A. arctotoides. Quantitative estimation of the chemical constituents of the crude extracts further revealed that the alkaloid content in the root higher (0.97 percent) than the shoot (0.64 percent). The quantity of flavonoids detected in the shoot (1.02 percent) was more than that observed in the root (0.35 percent). Others (phenolics and tannins) were marginal in the two plant parts. The results of the inhibitory effects of the root and shoot aqueous extract at the varying concentrations showed that root extract at 10 mg/ml considerably reduced the germination of cabbage, carrot, tomato and spinach seeds by 84.0, 83.2, 72.8 and 37.4 percent respectively. Incubation of the shoot extract at the same concentration resulted in 100 percent inhibition of cabbage and carrot seed germination whereas those of tomato and spinach were suppressed by 91.5 and 61.2 percent respectively. The two extracts at the varying concentrations also had a significant reduction on the radicle and plumule growth of the four vegetables. Addition of the shoot residue to the soil showed massive chlorosis, necrotic lesions and wilting of tomato and cabbage leaves under treatments C and D at 2 weeks after transplanting. The number of leaves, leaf area, dry shoot and root weight of the two vegetables grown in the amended soils were also drastically reduced. The inhibition percentages due to the addition of the three concentrations of A. arctotoides dried shoot residue on the dry shoot weight at 4 weeks after transplanting were 38.6, 45.5 and 70.3. for tomato and 57.5, 73.3 and 87.5 percent for cabbage. Similarly, the declines in the dry root weight of 61.3, 82.9.4 and 83.4 percent for tomato as well as 53.1, 54.7 and 67.2 percent for cabbages were recorded for the two vegetables under treatment B, C and D during the period. The results further showed that the dry fruit yield and shoot weight of tomato under the treatments B, C and D decreased with increase in shoot residue concentrations of A. arctotoides. Relative to treatment A, no significant differences were recorded in the dry head weight of cabbage under the residue treated groups. The reductions in the fruit yield and fresh head weight caused by treatments C and D were 37.2 and 84.8 percent for tomato and 30.9 and 72.4 percent for cabbage. The findings on the mineral contents in the leaves of the two vegetables revealed significant differences in the uptake of N, Mg, Na, Cu and Fe by tomato leaves. The concentrations of N, K, Na and Zn in cabbage leaves also differed. However, the P content was relatively constant in the leaves of the two vegetables at 4 and 12 weeks after transplanting. At 12 weeks after transplanting, the Fe content in soils with tomato and cabbage treatments C and D was greatly enhanced in comparison with the other nutrients. The residual N, P and Zn detected in soils planted to cabbage were similarly equal among all the groups including the control. Thus, under the greenhouse experiment, Arctotis arctotoides (L.f) O. Hoffm has been shown to contain some phytotoxic chemical compounds in its root and shoot materials. The compounds either singly or collectively have demonstrated some inhibitory potentials on the germination, growth and yields of cabbage, carrot, tomato and spinach evaluated in this study.
- Full Text:
- Date Issued: 2012
The saga of South African POWs in Angola, 1975-82
- Authors: Baines, Gary F
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69882 , vital:29592 , http://dx.doi.org/10.5787/40-2-999
- Description: This article narrates the story of nine soldiers captured during and shortly after Operation Savannah, the codename for the South African Defence Force invasion of Angola in 1975–6. Eight of these soldiers were captured in Angola in three separate incidents by Angolan and/or Cuban forces, whereas the last was abducted from northern Namibia by SWAPO (the South West Africa Peoples’ Organisation). The article then provides a chronological account of the sequels to this story that interweaves a number of threads: first, the account relates the South African government’s attempts to suppress press coverage of these stories for fear of the political ‘fall-out’ that the matter might cause amongst the white electorate and in case it jeopardised secret negotiations to secure the release of the prisoners; and second, it uncovers the role played by intermediaries, especially the International Committee of the Red Cross (ICRC), in the sensitive and fraught negotiation process. It will be shown that the South African authorities adopted divergent approaches when dealing with SWAPO and the Angolans/Cubans to secure the release of prisoners of war (POWs). This is because the South African authorities regarded the former as involved in an internal insurrection whereas the latter were members of the military forces of sovereign states. Accordingly, they paid lip service to the Geneva Conventions in the case of Angolan and Cuban POWs but treated captured SWAPO cadres as ‘terrorists’ or ‘criminals’.
- Full Text:
- Date Issued: 2012
- Authors: Baines, Gary F
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69882 , vital:29592 , http://dx.doi.org/10.5787/40-2-999
- Description: This article narrates the story of nine soldiers captured during and shortly after Operation Savannah, the codename for the South African Defence Force invasion of Angola in 1975–6. Eight of these soldiers were captured in Angola in three separate incidents by Angolan and/or Cuban forces, whereas the last was abducted from northern Namibia by SWAPO (the South West Africa Peoples’ Organisation). The article then provides a chronological account of the sequels to this story that interweaves a number of threads: first, the account relates the South African government’s attempts to suppress press coverage of these stories for fear of the political ‘fall-out’ that the matter might cause amongst the white electorate and in case it jeopardised secret negotiations to secure the release of the prisoners; and second, it uncovers the role played by intermediaries, especially the International Committee of the Red Cross (ICRC), in the sensitive and fraught negotiation process. It will be shown that the South African authorities adopted divergent approaches when dealing with SWAPO and the Angolans/Cubans to secure the release of prisoners of war (POWs). This is because the South African authorities regarded the former as involved in an internal insurrection whereas the latter were members of the military forces of sovereign states. Accordingly, they paid lip service to the Geneva Conventions in the case of Angolan and Cuban POWs but treated captured SWAPO cadres as ‘terrorists’ or ‘criminals’.
- Full Text:
- Date Issued: 2012
Illustrated medicines information for HIV/AIDS patients: influence on adherence,self-efficacy and health outcomes
- Authors: Barford, Kirsty-Lee
- Date: 2012
- Subjects: AIDS (Disease) -- Treatment -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Patients -- South Africa , HIV-positive persons -- South Africa , AIDS (Disease) -- Study and teaching -- South Africa , Antiretroviral agents -- South Africa , Communication in medicine -- South Africa , Communication in public health -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:3863 , http://hdl.handle.net/10962/d1015678
- Description: South Africa has an estimated 920 000 patients on antiretrovirals (ARVs), the largest number of patients in any country. ARV therapy demands adherence levels in excess of 95% to avoid development of drug resistance, but adherence to ARV therapy is estimated to be only between 50% and 70%. Poor medication adherence is acknowledged as a major public health problem, reducing the effectiveness of therapy and promoting resistance to ARVs. More than two thirds of the South African population have marginal reading skills and this significantly influences a patient’s ability to read and understand health-related information. Patient education materials tailored for the South African population could be a useful aid in facilitating communication with patients and perhaps impact positively on their medicine-taking behaviour. This behaviour is influenced by patient knowledge, beliefs, attitudes and expectations and includes self-management, self-efficacy and adherence. Self-efficacy, which refers to patient confidence in the ability to self-manage medicine taking, is a key factor influencing adherence. This study aimed to develop illustrated patient information leaflets (PILs) and medicine labels for all first-line ARV regimens used in the public health sector in South Africa and, using a randomised control study design, to investigate the impact of these illustrated information materials on knowledge, medication-taking behaviours and health outcomes in HIV/AIDS patients taking ARVs. To achieve this aim, the objectives were to assess HIV/AIDS and ARV-related knowledge, as well as self-efficacy and adherence to ARV therapy; to assess the influence of demographic variables on knowledge, adherence and self-efficacy; to assess the influence of the information materials on knowledge, self-efficacy and adherence and to assess the association of knowledge with health outcomes. Medicine labels and PILs, both English and isiXhosa, were developed for ARV regimens 1a, 1b, 1c and 1d. The 8-item Morisky Medication Adherence Scale (MMAS-8) and HIV Treatment Adherence Self Efficacy Scale (HIV-ASES) instruments for measuring respectively adherence and self-efficacy, were modified to optimize clarity, simplicity and cultural acceptability and were translated into isiXhosa using a multi-stage translation-back translation. The questions and the rating scales, for both the MMAS and HIV-ASES, underwent preliminary qualitative evaluation in focus group discussions. Patients were recruited from local Grahamstown clinics. A pilot study to evaluate applicability of the instruments was conducted in 16 isiXhosa AIDS patients on ARVs and the results from this study informed further modifications to the instruments. One hundred and seventeen patients were recruited for the randomised control trial and were randomly allocated to either control group (who received standard care) or experimental group (who received standard care as well as pictogram medicine labels and the illustrated PIL). Interviews were conducted at baseline and at one, three and six months. Data were analysed statistically using the t-test, chi-squared test and ANOVA (Analysis of Variance) at a 5% level of significance. Correlations were determined using Pearson and Spearman rho correlations. Approval was obtained from Rhodes University Ethical Standards Committee, Settlers Hospital Ethics Committee and the Eastern Cape Department of Health. The results of this research showed that illustrated PILs and medicine labels enhanced understanding of HIV/AIDS and ARV information, resulting in a mean overall knowledge score in the experimental group of 96%, which was significantly higher than the 75% measured in the control group. Variable knowledge scores were measured in three areas: baseline knowledge of general HIV/AIDS-related information was good at 87%, whereas knowledge scores relating to ARV-related information (60%) and side-effects (52%) were lower. These scores improved significantly in the experimental group over the 4 interviews during the 6 month trial duration, whereas in the control group, they fluctuated only slightly around the original baseline score. There was no significant influence of gender on knowledge score, whereas health literacy, education level and age tested (at one and three months) had a significant influence on knowledge. Self-efficacy and adherence results were high, indicating that the patients have confidence in their ability to adhere to the ARV therapy and to practice optimal self-care. Age, gender and education, in most cases, significantly influenced self-efficacy, but were found to have no effect on adherence. The CD4 count improved over the trial duration which may have been influenced by a number of factors, including better knowledge of ARVs and improved adherence. No significant parametric correlation was found between knowledge score and change in CD4 count, however, Spearman's rho showed significance (rs=0.498; p=0.022). Both patients and healthcare providers were highly enthusiastic about the illustrated labels and PILs, and indicated their desire for such materials to be routinely available to public sector HIV/AIDS patients. The isiXhosa version of the PIL was preferred by all the patients. These simple, easy-to-read leaflets and illustrated medication labels were shown to increase understanding and knowledge of ARVs and HIV/AIDS in low-literate patients, and their availability in the first-language of the patients was central to making them a highly useful information source.
- Full Text:
- Date Issued: 2012
- Authors: Barford, Kirsty-Lee
- Date: 2012
- Subjects: AIDS (Disease) -- Treatment -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Patients -- South Africa , HIV-positive persons -- South Africa , AIDS (Disease) -- Study and teaching -- South Africa , Antiretroviral agents -- South Africa , Communication in medicine -- South Africa , Communication in public health -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:3863 , http://hdl.handle.net/10962/d1015678
- Description: South Africa has an estimated 920 000 patients on antiretrovirals (ARVs), the largest number of patients in any country. ARV therapy demands adherence levels in excess of 95% to avoid development of drug resistance, but adherence to ARV therapy is estimated to be only between 50% and 70%. Poor medication adherence is acknowledged as a major public health problem, reducing the effectiveness of therapy and promoting resistance to ARVs. More than two thirds of the South African population have marginal reading skills and this significantly influences a patient’s ability to read and understand health-related information. Patient education materials tailored for the South African population could be a useful aid in facilitating communication with patients and perhaps impact positively on their medicine-taking behaviour. This behaviour is influenced by patient knowledge, beliefs, attitudes and expectations and includes self-management, self-efficacy and adherence. Self-efficacy, which refers to patient confidence in the ability to self-manage medicine taking, is a key factor influencing adherence. This study aimed to develop illustrated patient information leaflets (PILs) and medicine labels for all first-line ARV regimens used in the public health sector in South Africa and, using a randomised control study design, to investigate the impact of these illustrated information materials on knowledge, medication-taking behaviours and health outcomes in HIV/AIDS patients taking ARVs. To achieve this aim, the objectives were to assess HIV/AIDS and ARV-related knowledge, as well as self-efficacy and adherence to ARV therapy; to assess the influence of demographic variables on knowledge, adherence and self-efficacy; to assess the influence of the information materials on knowledge, self-efficacy and adherence and to assess the association of knowledge with health outcomes. Medicine labels and PILs, both English and isiXhosa, were developed for ARV regimens 1a, 1b, 1c and 1d. The 8-item Morisky Medication Adherence Scale (MMAS-8) and HIV Treatment Adherence Self Efficacy Scale (HIV-ASES) instruments for measuring respectively adherence and self-efficacy, were modified to optimize clarity, simplicity and cultural acceptability and were translated into isiXhosa using a multi-stage translation-back translation. The questions and the rating scales, for both the MMAS and HIV-ASES, underwent preliminary qualitative evaluation in focus group discussions. Patients were recruited from local Grahamstown clinics. A pilot study to evaluate applicability of the instruments was conducted in 16 isiXhosa AIDS patients on ARVs and the results from this study informed further modifications to the instruments. One hundred and seventeen patients were recruited for the randomised control trial and were randomly allocated to either control group (who received standard care) or experimental group (who received standard care as well as pictogram medicine labels and the illustrated PIL). Interviews were conducted at baseline and at one, three and six months. Data were analysed statistically using the t-test, chi-squared test and ANOVA (Analysis of Variance) at a 5% level of significance. Correlations were determined using Pearson and Spearman rho correlations. Approval was obtained from Rhodes University Ethical Standards Committee, Settlers Hospital Ethics Committee and the Eastern Cape Department of Health. The results of this research showed that illustrated PILs and medicine labels enhanced understanding of HIV/AIDS and ARV information, resulting in a mean overall knowledge score in the experimental group of 96%, which was significantly higher than the 75% measured in the control group. Variable knowledge scores were measured in three areas: baseline knowledge of general HIV/AIDS-related information was good at 87%, whereas knowledge scores relating to ARV-related information (60%) and side-effects (52%) were lower. These scores improved significantly in the experimental group over the 4 interviews during the 6 month trial duration, whereas in the control group, they fluctuated only slightly around the original baseline score. There was no significant influence of gender on knowledge score, whereas health literacy, education level and age tested (at one and three months) had a significant influence on knowledge. Self-efficacy and adherence results were high, indicating that the patients have confidence in their ability to adhere to the ARV therapy and to practice optimal self-care. Age, gender and education, in most cases, significantly influenced self-efficacy, but were found to have no effect on adherence. The CD4 count improved over the trial duration which may have been influenced by a number of factors, including better knowledge of ARVs and improved adherence. No significant parametric correlation was found between knowledge score and change in CD4 count, however, Spearman's rho showed significance (rs=0.498; p=0.022). Both patients and healthcare providers were highly enthusiastic about the illustrated labels and PILs, and indicated their desire for such materials to be routinely available to public sector HIV/AIDS patients. The isiXhosa version of the PIL was preferred by all the patients. These simple, easy-to-read leaflets and illustrated medication labels were shown to increase understanding and knowledge of ARVs and HIV/AIDS in low-literate patients, and their availability in the first-language of the patients was central to making them a highly useful information source.
- Full Text:
- Date Issued: 2012
The social and political identities of coloured women in the northern areas of Port Elizabeth
- Authors: Barker, Celeste Heloise
- Date: 2012
- Subjects: Women, Colored -- South Africa -- Port Elizabeth , Colored people (South Africa) -- Race identity , Ethnicity -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: vital:8261 , http://hdl.handle.net/10948/d1013081
- Description: This treatise explores the social and political identity of coloured women in the Nelson Mandela Bay Metro (NMBM) with the intention of understanding why some stereotypes of coloured women‟s identity have endured since colonialism in South Africa. Topic selection was stimulated by heated public response to a newspaper article (“Jou Ma se Kinders” (Your Mother‟s Children), (Roberts 2011: http://www.lifeissavage.com/) which negatively labeled and pigeon-holed coloured women‟s identity. With the notable exception of the Saartje Baartman story, most text selection in the Literature Review (Chapter 2) was informed by research in the Western Cape because studies have a patriarchal bias and there are scant records of coloured women‟s lives and identity in the East Cape, Port Elizabeth and the NMBM. The study includes select readings of literary theory and South African fiction from which examples were chosen to illustrate the longevity of stereotypes attached to coloured women‟s identity. Commemorative narrative highlights the role coloured women played and continue to play as their alternative histories or counter narratives embed alternative histories in group identity. A comparative historical analysis of racist and gendered policies and practices contextualises the social construction of coloured women‟s identity from the colonial period to the present time and a focus group discussion among ten female evictees from South End and Richmond ] Hill in Port Elizabeth (PE) generated rich details of coloured women‟s lives and experience in Port Elizabeth and the NMBM. Findings are captured in four themes: Living, Loving and Laughing; Religion and Resistance; Hardship and Trauma and Identity and Ambivalence. These themes highlight nostalgia, courage and humour; the special role played by religious affiliation and coloured people‟s successful resistance to the demolition and deconsecration of places of worship in PE together with pride and a sense of achievement which continues to influence coloured women‟s political identity in the NMBM. Police brutality, everyday racism and sexism, the impact of apartheid on matriculants and the influence of petty apartheid on coloured women‟s lives and identity, as well as participants‟ contradictory perceptions of their post-apartheid social and political identity which continue to be defined by a deficit discourse, are discussed and described in Chapter 4. Focus Group findings locate coloured women‟s identity in a milieu of racist and gendered laws, policies and practices. It is suggested that sexualised stereotypes of coloured women‟s commodification and second class status persist regardless of the South African transition to a constitutional democracy. Evidence is presented of coloured women as bounded storytellers who create a counter narrative to apartheid justification of forced removals.It is suggested that the counter narrative is a vehicle for group support, affirmation and the recovery of roots, identity and post apartheid heritage including records and memorabilia displayed in the South End Museum. As the field is under-researched it is recommended that further research should be conducted to include studies of the social and political identity of an expanded sample of coloured women representative of diverse ages and backgrounds in the rural and urban areas of South Africa.
- Full Text:
- Date Issued: 2012
- Authors: Barker, Celeste Heloise
- Date: 2012
- Subjects: Women, Colored -- South Africa -- Port Elizabeth , Colored people (South Africa) -- Race identity , Ethnicity -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: vital:8261 , http://hdl.handle.net/10948/d1013081
- Description: This treatise explores the social and political identity of coloured women in the Nelson Mandela Bay Metro (NMBM) with the intention of understanding why some stereotypes of coloured women‟s identity have endured since colonialism in South Africa. Topic selection was stimulated by heated public response to a newspaper article (“Jou Ma se Kinders” (Your Mother‟s Children), (Roberts 2011: http://www.lifeissavage.com/) which negatively labeled and pigeon-holed coloured women‟s identity. With the notable exception of the Saartje Baartman story, most text selection in the Literature Review (Chapter 2) was informed by research in the Western Cape because studies have a patriarchal bias and there are scant records of coloured women‟s lives and identity in the East Cape, Port Elizabeth and the NMBM. The study includes select readings of literary theory and South African fiction from which examples were chosen to illustrate the longevity of stereotypes attached to coloured women‟s identity. Commemorative narrative highlights the role coloured women played and continue to play as their alternative histories or counter narratives embed alternative histories in group identity. A comparative historical analysis of racist and gendered policies and practices contextualises the social construction of coloured women‟s identity from the colonial period to the present time and a focus group discussion among ten female evictees from South End and Richmond ] Hill in Port Elizabeth (PE) generated rich details of coloured women‟s lives and experience in Port Elizabeth and the NMBM. Findings are captured in four themes: Living, Loving and Laughing; Religion and Resistance; Hardship and Trauma and Identity and Ambivalence. These themes highlight nostalgia, courage and humour; the special role played by religious affiliation and coloured people‟s successful resistance to the demolition and deconsecration of places of worship in PE together with pride and a sense of achievement which continues to influence coloured women‟s political identity in the NMBM. Police brutality, everyday racism and sexism, the impact of apartheid on matriculants and the influence of petty apartheid on coloured women‟s lives and identity, as well as participants‟ contradictory perceptions of their post-apartheid social and political identity which continue to be defined by a deficit discourse, are discussed and described in Chapter 4. Focus Group findings locate coloured women‟s identity in a milieu of racist and gendered laws, policies and practices. It is suggested that sexualised stereotypes of coloured women‟s commodification and second class status persist regardless of the South African transition to a constitutional democracy. Evidence is presented of coloured women as bounded storytellers who create a counter narrative to apartheid justification of forced removals.It is suggested that the counter narrative is a vehicle for group support, affirmation and the recovery of roots, identity and post apartheid heritage including records and memorabilia displayed in the South End Museum. As the field is under-researched it is recommended that further research should be conducted to include studies of the social and political identity of an expanded sample of coloured women representative of diverse ages and backgrounds in the rural and urban areas of South Africa.
- Full Text:
- Date Issued: 2012
Using an intelligent self-service solution to support telecommunication service provisioning
- Authors: Barlow, Sherwin Riaan
- Date: 2012
- Subjects: Telecommunication systems -- Management , Electronic commerce -- Computer programs , Web applications
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10484 , http://hdl.handle.net/10948/d1013417
- Description: The increasing competition between telecommunication service providers (TSPs) and the large amounts of human resource costs incurred to provision telecommunication services to small, medium and micro enterprises (SMMEs), highlight the need for effective self-service provisioning methods to reduce costs. Existing service provisioning methods do not effectively support SMMEs in the service provisioning process. The current methods used are manual and Web-based. The manual service provisioning method is labour and time-intensive. TSPs are being forced to cut human resource costs as the profit margins for provisioning services are narrow due to competition. The current web-based systems do not allow SMMEs to effectively purchase services as they provide long textual lists to consult and limited information about services. The objective of this research was to develop an intelligent web-based self-service system to support SMMEs in telecommunication service provisioning, using a Design Science Research methodology. A constraint-based, knowledge-based recommender system was selected as the most appropriate intelligent system to support telecommunication service provisioning. A prototype called SelPro was developed as a solution to address the shortcomings of the current ineffective service provisioning methods available for SMMEs. SelPro incorporates an interactive wizard-style user interface with dynamic recommendations to support novice users as well as an expert interface which provides less user support. An expert review and a user study were conducted to determine if SelPro was usable, useful and effective. SelPro was perceived as being usable for SMMEs wishing to purchase telecommunication services. Expert participants were satisfied with the usability of SelPro and perceived it as being useful, easy to use and easy to learn. SelPro was considered effective because of the high task success ratings provided by the participants using the two interfaces. The research determined that intelligent web-based self-service provisioning can be used to effectively support SMMEs in telecommunication service provisioning. General design recommendations for similar systems were proposed and future work will involve using intelligent systems to support large enterprises in telecommunication service provisioning.
- Full Text:
- Date Issued: 2012
- Authors: Barlow, Sherwin Riaan
- Date: 2012
- Subjects: Telecommunication systems -- Management , Electronic commerce -- Computer programs , Web applications
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10484 , http://hdl.handle.net/10948/d1013417
- Description: The increasing competition between telecommunication service providers (TSPs) and the large amounts of human resource costs incurred to provision telecommunication services to small, medium and micro enterprises (SMMEs), highlight the need for effective self-service provisioning methods to reduce costs. Existing service provisioning methods do not effectively support SMMEs in the service provisioning process. The current methods used are manual and Web-based. The manual service provisioning method is labour and time-intensive. TSPs are being forced to cut human resource costs as the profit margins for provisioning services are narrow due to competition. The current web-based systems do not allow SMMEs to effectively purchase services as they provide long textual lists to consult and limited information about services. The objective of this research was to develop an intelligent web-based self-service system to support SMMEs in telecommunication service provisioning, using a Design Science Research methodology. A constraint-based, knowledge-based recommender system was selected as the most appropriate intelligent system to support telecommunication service provisioning. A prototype called SelPro was developed as a solution to address the shortcomings of the current ineffective service provisioning methods available for SMMEs. SelPro incorporates an interactive wizard-style user interface with dynamic recommendations to support novice users as well as an expert interface which provides less user support. An expert review and a user study were conducted to determine if SelPro was usable, useful and effective. SelPro was perceived as being usable for SMMEs wishing to purchase telecommunication services. Expert participants were satisfied with the usability of SelPro and perceived it as being useful, easy to use and easy to learn. SelPro was considered effective because of the high task success ratings provided by the participants using the two interfaces. The research determined that intelligent web-based self-service provisioning can be used to effectively support SMMEs in telecommunication service provisioning. General design recommendations for similar systems were proposed and future work will involve using intelligent systems to support large enterprises in telecommunication service provisioning.
- Full Text:
- Date Issued: 2012
An investigation into refuge trauma experiences in an ethnic Somali community in Port Elizabeth, South Africa
- Barnwell, Garret Christopher
- Authors: Barnwell, Garret Christopher
- Date: 2012
- Subjects: Refugees -- Legal status, laws, etc. -- South Africa -- Port Elizabeth , Somali diaspora , Forced migration -- South Africa -- Port Elizabeth , Refugees -- Abuse of -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8275 , http://hdl.handle.net/10948/d1016061
- Description: The study aimed to explore and describe the forced migration experiences of Somali refugees living in Port Elizabeth, South Africa and the impact of refugee-specific trauma on this population. A mixed method triangulation research design with a quantitative weighting was employed and purposive snowball, non-probability sampling was used to construct a sample of 30 adult Somali refugees from Port Elizabeth’s Korsten community. Participants were included in the study if they fulfilled the pre-defined inclusion criteria of having successfully applied for refugee status, having resided in South Africa for at least six months and being 18 years or older. A semi-structured interview questionnaire was developed by the researcher to operationalise the constructs being measured. The questionnaire comprised a biographical and antecedent event(s) questionnaires as well as sections of the Harvard Trauma Questionnaire Revised Version. Data was then analysed via exploratory descriptive statistics and correlation coefficients. The research found that the majority of Somali refugees cited conflict, insecurity and instability as the mainn reasons for leaving their country of origin, suggesting the basic need for safety and security was unmet. One third of the sample reported that the main reason for leaving was the same as their most traumatic life event. The average participant had experienced 16 traumatic events and experienced 23 trauma symptoms on average, demonstrating high levels of trauma among the study population. The study recommends that the link between the main reason for forced migration and refugee trauma be explored.
- Full Text:
- Date Issued: 2012
- Authors: Barnwell, Garret Christopher
- Date: 2012
- Subjects: Refugees -- Legal status, laws, etc. -- South Africa -- Port Elizabeth , Somali diaspora , Forced migration -- South Africa -- Port Elizabeth , Refugees -- Abuse of -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8275 , http://hdl.handle.net/10948/d1016061
- Description: The study aimed to explore and describe the forced migration experiences of Somali refugees living in Port Elizabeth, South Africa and the impact of refugee-specific trauma on this population. A mixed method triangulation research design with a quantitative weighting was employed and purposive snowball, non-probability sampling was used to construct a sample of 30 adult Somali refugees from Port Elizabeth’s Korsten community. Participants were included in the study if they fulfilled the pre-defined inclusion criteria of having successfully applied for refugee status, having resided in South Africa for at least six months and being 18 years or older. A semi-structured interview questionnaire was developed by the researcher to operationalise the constructs being measured. The questionnaire comprised a biographical and antecedent event(s) questionnaires as well as sections of the Harvard Trauma Questionnaire Revised Version. Data was then analysed via exploratory descriptive statistics and correlation coefficients. The research found that the majority of Somali refugees cited conflict, insecurity and instability as the mainn reasons for leaving their country of origin, suggesting the basic need for safety and security was unmet. One third of the sample reported that the main reason for leaving was the same as their most traumatic life event. The average participant had experienced 16 traumatic events and experienced 23 trauma symptoms on average, demonstrating high levels of trauma among the study population. The study recommends that the link between the main reason for forced migration and refugee trauma be explored.
- Full Text:
- Date Issued: 2012
Development of molecularly imprinted polymer based solid phase extraction sorbents for the selective cleanup of food and pharmaceutical residue samples
- Authors: Batlokwa, Bareki Shima
- Date: 2012
- Subjects: Sorbents -- Research Nanofibers -- Research Aflatoxins -- Research Electrospinning -- Research Extraction (Chemistry) -- Research
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4309 , http://hdl.handle.net/10962/d1004967
- Description: This thesis presents the development of chlorophyll, cholic acid, aflatoxin B1 molecularly imprinted polymer (MIP) particles and cholic acid MIP nanofibers for application as selective solid phase extraction (SPE) sorbents. The particles were prepared by bulk polymerization and the nanofibers by a novel approach combining molecular imprinting and electrospinning technology. The AFB1 MIP particles were compared with an aflatoxin specific immunoextraction sorbent in cleaning-up and pre-concentrating aflatoxins from nut extracts. They both recorded high extraction efficiencies (EEs) of > 97 % in selectively extracting the aflatoxins (AFB1, AFB2, AFG1 and AFG2). High reproducibility marked by the low %RSDs of < 1% and low LODs of ≤ 0.02 ng/g were calculated in all cases. The LODs were within the monitoring requirements of the European Commission. The results were validated with a peanut butter certified reference material. The chlorophyll MIP on the other hand selectively removed chlorophyll that would otherwise interfere during pesticide residue analysis (PRA) from > 0.6 to <0.09 Au in green plants extracts. The extracted chlorophyll was removed to far below the level of ≥ 0.399 Au that is usually associated with interference during PRA. Furthermore, the MIP demonstrated better selectivity by removing only chlorophyll (> 99%) in the presence of planar pesticides than the currently employed graphitized carbon black (GCB) that removed both the chlorophyll (> 88%) and planar pesticides (> 89%). For the interfering cholic acid during drug residue analysis, cholic acid MIP electrospun nanofibers demonstrated to be more sensitive and possessing higher loading capacity than the MIP particles. 100% cholic acid was removed by the nanofibers from standard solutions relative to 80% by the particles. This showed that the nanofibers have better performance than the micro particles and as such have potential to replace the particle based SPE sorbents that are currently in use. All the templates were optimally removed from the prepared MIPs by employing a novel pressurized hot water extraction template removal method that was used for the first time in this thesis. The method employed only water, an environmentally friendly solvent to remove templates to ≥ 99.6% with template residual bleeding of ≤ 0.02%.
- Full Text:
- Date Issued: 2012
- Authors: Batlokwa, Bareki Shima
- Date: 2012
- Subjects: Sorbents -- Research Nanofibers -- Research Aflatoxins -- Research Electrospinning -- Research Extraction (Chemistry) -- Research
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4309 , http://hdl.handle.net/10962/d1004967
- Description: This thesis presents the development of chlorophyll, cholic acid, aflatoxin B1 molecularly imprinted polymer (MIP) particles and cholic acid MIP nanofibers for application as selective solid phase extraction (SPE) sorbents. The particles were prepared by bulk polymerization and the nanofibers by a novel approach combining molecular imprinting and electrospinning technology. The AFB1 MIP particles were compared with an aflatoxin specific immunoextraction sorbent in cleaning-up and pre-concentrating aflatoxins from nut extracts. They both recorded high extraction efficiencies (EEs) of > 97 % in selectively extracting the aflatoxins (AFB1, AFB2, AFG1 and AFG2). High reproducibility marked by the low %RSDs of < 1% and low LODs of ≤ 0.02 ng/g were calculated in all cases. The LODs were within the monitoring requirements of the European Commission. The results were validated with a peanut butter certified reference material. The chlorophyll MIP on the other hand selectively removed chlorophyll that would otherwise interfere during pesticide residue analysis (PRA) from > 0.6 to <0.09 Au in green plants extracts. The extracted chlorophyll was removed to far below the level of ≥ 0.399 Au that is usually associated with interference during PRA. Furthermore, the MIP demonstrated better selectivity by removing only chlorophyll (> 99%) in the presence of planar pesticides than the currently employed graphitized carbon black (GCB) that removed both the chlorophyll (> 88%) and planar pesticides (> 89%). For the interfering cholic acid during drug residue analysis, cholic acid MIP electrospun nanofibers demonstrated to be more sensitive and possessing higher loading capacity than the MIP particles. 100% cholic acid was removed by the nanofibers from standard solutions relative to 80% by the particles. This showed that the nanofibers have better performance than the micro particles and as such have potential to replace the particle based SPE sorbents that are currently in use. All the templates were optimally removed from the prepared MIPs by employing a novel pressurized hot water extraction template removal method that was used for the first time in this thesis. The method employed only water, an environmentally friendly solvent to remove templates to ≥ 99.6% with template residual bleeding of ≤ 0.02%.
- Full Text:
- Date Issued: 2012
An ion-imprinted polymer for the selective extraction of mercury(II) ions in aqueous media
- Batlokwa, Bareki Shima, Chimuka, Luke, Tshentu, Zenixole, Cukrowska, Ewa, Torto, Nelson
- Authors: Batlokwa, Bareki Shima , Chimuka, Luke , Tshentu, Zenixole , Cukrowska, Ewa , Torto, Nelson
- Date: 2012
- Language: English
- Type: Article
- Identifier: vital:6566 , http://hdl.handle.net/10962/d1004125
- Description: A double-imprinted polymer exhibiting high sensitivity for mercury(II) in aqueous solution is presented. Polymer particles imprinted with mercury(II) were synthesised by copolymerising the functional and cross-linking monomers, N’–[3– (Trimethoxysilyl)–propyl]diethylenetriamine (TPET) and tetraethylorthosilicate (TEOS). A double-imprinting procedure employing hexadecyltrimethylammonium bromide (CTAB), as a second template to improve the efficiency of the polymer, was adopted. The imprinted polymer was characterised by FTIR, scanning electron microscopy (SEM) and the average size determined by screen analysis using standard test sieves. Relative selective coefficients (k`) of the imprinted polymer evaluated from selective binding studies between Hg2+ and Cu2+ or Hg2+ and Cd2+ were 10 588 and 3 147, respectively. These values indicated highly-favoured Hg2+ extractions over the 2 competing ions. The results of spiked and real water samples showed high extraction efficiencies of Hg2+ ions, (over 84%) as evaluated from the detected unextracted Hg2+ ions by ICP-OES. The method exhibited a dynamic response concentration range for Hg2+ between 0.01 and 20 μg/mℓ, with a detection limit (LOD, 3σ) of 0.000036 μg/mℓ (36 ng/ℓ) that meets the monitoring requirements for the USA EPA of 2 000 ng/ℓ for Hg2+ in drinking water. Generally, the data (n=10) had percentage relative standard deviations (%RSD) of less than 4%. Satisfactory results were also obtained when the prepared sorbent was applied for the pre-concentration of Hg2+ from an aqueous certified reference material. These findings indicate that the double-imprinted polymer has potential to be used as an efficient extraction material for the selective pre–concentration of mercury(II) ions in aqueous environments.
- Full Text:
- Date Issued: 2012
- Authors: Batlokwa, Bareki Shima , Chimuka, Luke , Tshentu, Zenixole , Cukrowska, Ewa , Torto, Nelson
- Date: 2012
- Language: English
- Type: Article
- Identifier: vital:6566 , http://hdl.handle.net/10962/d1004125
- Description: A double-imprinted polymer exhibiting high sensitivity for mercury(II) in aqueous solution is presented. Polymer particles imprinted with mercury(II) were synthesised by copolymerising the functional and cross-linking monomers, N’–[3– (Trimethoxysilyl)–propyl]diethylenetriamine (TPET) and tetraethylorthosilicate (TEOS). A double-imprinting procedure employing hexadecyltrimethylammonium bromide (CTAB), as a second template to improve the efficiency of the polymer, was adopted. The imprinted polymer was characterised by FTIR, scanning electron microscopy (SEM) and the average size determined by screen analysis using standard test sieves. Relative selective coefficients (k`) of the imprinted polymer evaluated from selective binding studies between Hg2+ and Cu2+ or Hg2+ and Cd2+ were 10 588 and 3 147, respectively. These values indicated highly-favoured Hg2+ extractions over the 2 competing ions. The results of spiked and real water samples showed high extraction efficiencies of Hg2+ ions, (over 84%) as evaluated from the detected unextracted Hg2+ ions by ICP-OES. The method exhibited a dynamic response concentration range for Hg2+ between 0.01 and 20 μg/mℓ, with a detection limit (LOD, 3σ) of 0.000036 μg/mℓ (36 ng/ℓ) that meets the monitoring requirements for the USA EPA of 2 000 ng/ℓ for Hg2+ in drinking water. Generally, the data (n=10) had percentage relative standard deviations (%RSD) of less than 4%. Satisfactory results were also obtained when the prepared sorbent was applied for the pre-concentration of Hg2+ from an aqueous certified reference material. These findings indicate that the double-imprinted polymer has potential to be used as an efficient extraction material for the selective pre–concentration of mercury(II) ions in aqueous environments.
- Full Text:
- Date Issued: 2012
The integration of mapwork and environmental issues using local context in FET Geography: an investigation of current pedagogic practices to inform professional development
- Authors: Batyi, Kekeletso Rejoyce
- Date: 2012
- Subjects: Geography -- South Africa -- Grahamstown -- Study and teaching (Secondary) Maps -- Study and teaching (Secondary) -- South Africa -- Grahamstown Environmental education -- Study and teaching (Secondary) -- South Africa -- Grahamstown Teachers -- Training of -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1580 , http://hdl.handle.net/10962/d1003462
- Description: This is an interpretative case study of four Grahamstown Education District Further Education and Training (FET) schools. The study sets out to investigate how Geography teachers integrate mapwork and environmental issues using local context, with the intention of providing insights for future professional development. Data for this study were generated using qualitative methods such as document analysis, semi-structured interviews and lesson observations. Interviews were conducted with geography teachers, the subject advisor and a workshop facilitator. The evidence generated in the study revealed that contrary to the integrative design of the curriculum, there is a superficial integration of mapwork and environmental issues as well as a cursory reference to and use of local context. This was noted in both professional development support workshops and classroom practice. The study finds that efforts to improve performance in geography need to pay closer attention to curriculum policy that calls for an integration and localization of knowledge and skills for coherence and relevance. It also notes that there is a need for a focus on real-world problem solving in social, economic, cultural and physical environments through the use of inquiry-based local fieldwork. Local investigations provide an integrative space for content and skills as well as being an important point of reference from which learners can compare and contrast issues in other places such as provincial, national, continental, and global locations. A professional development programme that emphasizes integration and contextualization alongside the current focus on basic skills training is proposed to improve what teachers are delivering in the classroom and to support enquiry-based fieldwork and research to strengthen a place-based relevance in local, national and international contexts. Finally an exemplar for professional development is briefly developed for the topic of soil erosion.
- Full Text:
- Date Issued: 2012
- Authors: Batyi, Kekeletso Rejoyce
- Date: 2012
- Subjects: Geography -- South Africa -- Grahamstown -- Study and teaching (Secondary) Maps -- Study and teaching (Secondary) -- South Africa -- Grahamstown Environmental education -- Study and teaching (Secondary) -- South Africa -- Grahamstown Teachers -- Training of -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1580 , http://hdl.handle.net/10962/d1003462
- Description: This is an interpretative case study of four Grahamstown Education District Further Education and Training (FET) schools. The study sets out to investigate how Geography teachers integrate mapwork and environmental issues using local context, with the intention of providing insights for future professional development. Data for this study were generated using qualitative methods such as document analysis, semi-structured interviews and lesson observations. Interviews were conducted with geography teachers, the subject advisor and a workshop facilitator. The evidence generated in the study revealed that contrary to the integrative design of the curriculum, there is a superficial integration of mapwork and environmental issues as well as a cursory reference to and use of local context. This was noted in both professional development support workshops and classroom practice. The study finds that efforts to improve performance in geography need to pay closer attention to curriculum policy that calls for an integration and localization of knowledge and skills for coherence and relevance. It also notes that there is a need for a focus on real-world problem solving in social, economic, cultural and physical environments through the use of inquiry-based local fieldwork. Local investigations provide an integrative space for content and skills as well as being an important point of reference from which learners can compare and contrast issues in other places such as provincial, national, continental, and global locations. A professional development programme that emphasizes integration and contextualization alongside the current focus on basic skills training is proposed to improve what teachers are delivering in the classroom and to support enquiry-based fieldwork and research to strengthen a place-based relevance in local, national and international contexts. Finally an exemplar for professional development is briefly developed for the topic of soil erosion.
- Full Text:
- Date Issued: 2012
Savings behaviour in selected poor townships of the Kouga municipal district
- Authors: Baxter, Chad
- Date: 2012
- Subjects: Saving and investment -- South Africa , South Africa -- Economic policy
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9009 , http://hdl.handle.net/10948/d1014540
- Description: This study considers the nature of savings behaviour amongst low income earners residing in the township areas of Kouga Municipal District. It reflects on the popularity and persistence of informal savings and credit associations, also known as stokvels, in these communities in the face of an increase in the availability of formal savings products. This study argues that despite financial deepening taking place within the South African economy, the popularity and widespread usage of stokvels can largely be attributed to the lack of appropraite formal products available for low income earners. This study does not conclude that the usage of informal savings products results in increased savings behaviours amongst this group, but it does conclude that they provide a suitable mechanism in which savings can take place.
- Full Text:
- Date Issued: 2012
- Authors: Baxter, Chad
- Date: 2012
- Subjects: Saving and investment -- South Africa , South Africa -- Economic policy
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9009 , http://hdl.handle.net/10948/d1014540
- Description: This study considers the nature of savings behaviour amongst low income earners residing in the township areas of Kouga Municipal District. It reflects on the popularity and persistence of informal savings and credit associations, also known as stokvels, in these communities in the face of an increase in the availability of formal savings products. This study argues that despite financial deepening taking place within the South African economy, the popularity and widespread usage of stokvels can largely be attributed to the lack of appropraite formal products available for low income earners. This study does not conclude that the usage of informal savings products results in increased savings behaviours amongst this group, but it does conclude that they provide a suitable mechanism in which savings can take place.
- Full Text:
- Date Issued: 2012