https://commons.ufh.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide-based inhibitor design: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38735 Wed 12 May 2021 23:42:41 SAST ]]> Role of structural bioinformatics in drug discovery by computational SNP analysis: analyzing variation at the protein level https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35832 Wed 12 May 2021 23:08:21 SAST ]]> Development of Bioinformatics Infrastructure for Genomics Research: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38722 Wed 12 May 2021 23:02:21 SAST ]]> How to establish a bioinformatics postgraduate degree programme—a case study from South Africa https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35641 Wed 12 May 2021 19:45:25 SAST ]]> Bioinformatics education—perspectives and challenges out of Africa https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35420 Wed 12 May 2021 19:35:39 SAST ]]> Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35647 Wed 12 May 2021 19:28:13 SAST ]]> Establishment of “The South African Bioinformatics Student Council” and activity highlights: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38723 Wed 12 May 2021 19:08:01 SAST ]]> Analysis of protein thermostability enhancing factors in industrially important thermus bacteria species https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35404 Wed 12 May 2021 18:42:46 SAST ]]> Bioinformatic characterization of type-specific sequence and structural features in auxiliary activity family 9 proteins: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38732 Wed 12 May 2021 18:29:25 SAST ]]> Analysis of non-peptidic compounds as potential malarial inhibitors against plasmodial cysteine proteases via integrated virtual screening workflow https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35403 Wed 12 May 2021 18:29:01 SAST ]]> Modulation of human Hsp90α conformational dynamics by allosteric ligand interaction at the c-terminal domain: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38736 Wed 12 May 2021 18:14:57 SAST ]]> Hepatitis C and HIV Coinfection in Developing Countries: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38721 Wed 12 May 2021 18:14:14 SAST ]]> Allosteric modulation of conformational dynamics in human Hsp90α: a computational study https://commons.ufh.ac.za/vital/access/manager/Repository/vital:29276 Wed 12 May 2021 17:51:35 SAST ]]> Probing the structural dynamics of the Plasmodium falciparum tunneling-fold enzyme 6-pyruvoyl tetrahydropterin synthase to reveal allosteric drug targeting sites: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41008 Wed 12 May 2021 17:47:32 SAST ]]> No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38725 Wed 12 May 2021 17:25:31 SAST ]]> Homology modeling and docking of AahII-Nanobody complexes reveal the epitope binding site on AahII scorpion toxin https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35637 Wed 12 May 2021 16:48:38 SAST ]]> Plasmodium falciparum Hop: detailed analysis on complex formation with Hsp70 and Hsp90 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35810 Wed 12 May 2021 16:44:52 SAST ]]> Bioinformatics and data analysis in microbiology: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38710 Wed 12 May 2021 16:10:00 SAST ]]> Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41000 Wed 12 May 2021 15:10:52 SAST ]]> In silico study of Plasmodium 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) for identification of novel inhibitors from SANCDB: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40973 Wed 12 May 2021 15:07:02 SAST ]]> Integrated computational approaches and tools for allosteric drug discovery: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41004 Wed 12 May 2021 14:59:07 SAST ]]> Allosteric site modulators: a case study for falcipains as malarial drug targets https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40974 Wed 12 May 2021 14:55:59 SAST ]]> Discorhabdin N, a South African Natural Compound, for Hsp72 and Hsc70 Allosteric Modulation: combined study of molecular modeling and dynamic residue network analysis https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40999 Wed 12 May 2021 14:55:59 SAST ]]> Establishing computational approaches towards identifying malarial allosteric modulators: a case study of plasmodium falciparum hsp70s https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41003 Wed 12 May 2021 14:55:35 SAST ]]> Understanding the Pyrimethamine drug resistance mechanism via combined molecular dynamics and dynamic residue network analysis: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41005 Wed 12 May 2021 14:51:19 SAST ]]> Computational analysis of missense mutations from the human Macrophage Migration Inhibitory Factor (MIF) protein by Molecular Dynamics Simulations and Dynamic Residue Network Analysis: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41021 Wed 12 May 2021 14:50:11 SAST ]]> Novel potential antimalarials through drug repurposing and multitargeting: a Computational Approach https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40972 Wed 12 May 2021 14:42:28 SAST ]]> Mechanism of action of non-synonymous single nucleotide variations associated with α-carbonic anhydrase II deficiency: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40970 Wed 12 May 2021 14:37:44 SAST ]]> Impact of emerging mutations on the dynamic properties the SARS-CoV-2 main protease: an in silico investigation https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41006 Wed 12 May 2021 14:37:26 SAST ]]> South African Abietane Diterpenoids and their analogs as potential antimalarials: novel insights from hybrid computational approaches https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40971 Wed 12 May 2021 14:34:08 SAST ]]> Plasmodium falciparum Hop: detailed analysis on complex formation with Hsp70 and Hsp90 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41046 Wed 12 May 2021 14:25:30 SAST ]]> No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40997 Wed 12 May 2021 14:22:12 SAST ]]> The role of structural bioinformatics in drug discovery via computational SNP analysis–a proposed protocol for analyzing variation at the protein level: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40996 Wed 12 May 2021 14:08:06 SAST ]]> SANCDB: a South African natural compound database https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40994 Wed 12 May 2021 14:03:39 SAST ]]> Impact of early pandemic stage mutations on molecular dynamics of SARS-CoV-2 Mpro: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40835 Wed 12 May 2021 13:58:21 SAST ]]> JMS: an open source workflow management system and web-based cluster front-end for high performance computing https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40993 Wed 12 May 2021 13:54:24 SAST ]]> Allosteric Modulation of Human Hsp90α Conformational Dynamics: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40998 Wed 12 May 2021 13:47:36 SAST ]]> Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41001 Wed 04 Aug 2021 14:30:33 SAST ]]> AMBER force field parameters for the Zn (II) ions of the tunneling-fold enzymes GTP cyclohydrolase I and 6-pyruvoyl tetrahydropterin synthase: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41009 Tue 09 Aug 2022 05:59:32 SAST ]]> Potential repurposing of four FDA approved compounds with antiplasmodial activity identified through proteome scale computational drug discovery and in vitro assay https://commons.ufh.ac.za/vital/access/manager/Repository/vital:42830 Tue 09 Aug 2022 05:58:00 SAST ]]> The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38708 Tue 06 Jul 2021 09:08:41 SAST ]]> MODE-TASK: Large-scale protein motion tools https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35746 Thu 20 Jul 2023 10:40:02 SAST ]]> Structural Characterization of Carbonic Anhydrase VIII and Effects of Missense Single Nucleotide Variations to Protein Structure and Function: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38873 Thu 13 May 2021 08:22:03 SAST ]]> Structure based docking and molecular dynamic studies of plasmodial cysteine proteases against a South African natural compound and its analogs: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38703 Thu 13 May 2021 06:45:08 SAST ]]> PRIMO: an interactive homology modeling pipeline https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38726 Thu 13 May 2021 06:26:49 SAST ]]> JMS: a workflow management system and web-based cluster front-end for the Torque resource manager https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38705 Thu 13 May 2021 06:17:11 SAST ]]> The development of computational biology in South Africa: successes achieved and lessons learnt https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38731 Thu 13 May 2021 06:06:06 SAST ]]> Sequence and domain conservation of the coelacanth Hsp40 and Hsp90 chaperones suggests conservation of function https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35936 Thu 13 May 2021 05:39:24 SAST ]]> HUMA: A platform for the analysis of genetic variation in humans https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35642 Thu 13 May 2021 04:36:27 SAST ]]> Comparative structural bioinformatics analysis of Bacillus amyloliquefaciens chemotaxis proteins within Bacillus subtilis group https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35521 Thu 13 May 2021 04:14:34 SAST ]]> The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38729 Thu 13 May 2021 04:04:33 SAST ]]> Study of protein complexes via homology modeling, applied to cysteine proteases and their protein inhibitors: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38707 Thu 13 May 2021 03:55:27 SAST ]]> Human, vector and parasite Hsp90 proteins: a comparative bioinformatics analysis https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38704 Thu 13 May 2021 03:52:50 SAST ]]> Determining the unbinding events and conserved motions associated with the pyrazinamide release due to resistance mutations of Mycobacterium tuberculosis pyrazinamidase: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38781 Thu 13 May 2021 03:45:09 SAST ]]> Structure-based analysis of single nucleotide variants in the renin-angiotensinogen complex: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38700 Thu 13 May 2021 02:34:41 SAST ]]> Plasmodium falciparum Hsp70-x : a heat shock protein at the host-parasite interface https://commons.ufh.ac.za/vital/access/manager/Repository/vital:6489 Thu 13 May 2021 02:32:07 SAST ]]> Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38733 Thu 13 May 2021 02:23:22 SAST ]]> Perturbation–Response Scanning reveals key residues for Allosteric Control in Hsp70: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38718 Thu 13 May 2021 01:31:30 SAST ]]> SANCDB: a South African natural compound database https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38730 Thu 13 May 2021 01:19:41 SAST ]]> The determination of CHARMM force field parameters for the Mg2+ containing HIV-1 integrase: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38713 Thu 13 May 2021 00:55:55 SAST ]]> Identification of Selective Novel Hits against Plasmodium falciparum Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using in silico Approaches: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38817 Thu 13 May 2021 00:42:15 SAST ]]> The evaluation and validation of copper (II) force field parameters of the Auxiliary Activity family 9 enzymes: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38719 Thu 13 May 2021 00:03:53 SAST ]]> Improving fold resistance prediction of HIV-1 against protease and reverse transcriptase inhibitors using artificial neural networks: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38724 Thu 11 Aug 2022 06:27:34 SAST ]]> Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38712 Thu 11 Aug 2022 06:27:06 SAST ]]> MD-TASK: a software suite for analyzing molecular dynamics trajectories https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35735 Mon 05 Jul 2021 15:05:38 SAST ]]> Unraveling the Motions behind Enterovirus 71 Uncoating: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38715 Mon 05 Jul 2021 15:05:35 SAST ]]> Interacting motif networks located in hotspots associated with RNA release are conserved in Enterovirus capsids https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35704 Fri 09 Feb 2024 15:20:05 SAST ]]> The In Silico Prediction of hotspot residues that contribute to the structural stability of subunit interfaces of a Picornavirus Capsid: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38919 Fri 09 Feb 2024 15:20:02 SAST ]]> Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38702 Fri 09 Feb 2024 15:20:00 SAST ]]> The generation and characterisation of neutralising antibodies against the Theiler’s murine encephalomyelitis virus (TMEV) GDVII capsid reveals the potential binding site of the host cell co-receptor, heparan sulfate: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38717 Fri 09 Feb 2024 15:20:00 SAST ]]>