https://commons.ufh.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Selection and characterization of suitable lipid excipients for use in the manufacture of didanosine-loaded solid lipid nanoparticles and nanostructured lipid carriers https://commons.ufh.ac.za/vital/access/manager/Repository/vital:44156 Tue 14 May 2024 11:59:25 SAST ]]> Evaluation of the in vitro differential protein adsorption patterns of didanosine-loaded nanostructured lipid carriers (NLCs) for potential targeting to the brain https://commons.ufh.ac.za/vital/access/manager/Repository/vital:44160 Tue 14 May 2024 11:58:13 SAST ]]> The use of hot and cold high pressure homogenization to enhance the loading capacity and encapsulation efficiency of nanostructured lipid carriers for the hydrophilic antiretroviral drug, didanosine for potential administration to paediatric patients https://commons.ufh.ac.za/vital/access/manager/Repository/vital:44170 Tue 14 May 2024 11:57:11 SAST ]]> Short term stability testing of efavirenz-loaded solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) dispersions https://commons.ufh.ac.za/vital/access/manager/Repository/vital:44000 90%. The optimized nanocarriers exhibited biphasic in vitro release patterns with an initial burst release during the initial 0–3 h followed by sustained release over a 24 h period The colloidal systems showed excellent stability in terms of Zeta potential, particle size, polydispersity index and encapsulation efficiency when stored for 8 weeks at 25 °C/60% RH in comparison to when stored at 40 °C/75% RH. The formulations manufactured using the optimized conditions and composition proved to be physically stable as aqueous dispersions.]]> Tue 14 May 2024 11:14:37 SAST ]]> Preformulation studies of efavirenz with lipid excipients using thermal and spectroscopic techniques https://commons.ufh.ac.za/vital/access/manager/Repository/vital:43934 Tue 14 May 2024 11:13:58 SAST ]]> The use of experimental design for the development and validation of an HPLC-ECD method for the quantitation of efavirenz https://commons.ufh.ac.za/vital/access/manager/Repository/vital:44006 Tue 14 May 2024 10:59:25 SAST ]]>