https://commons.ufh.ac.za/vital/access/manager/Index en-us 5 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65806 Wed 24 Jan 2024 20:21:09 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65793 Wed 10 Jan 2024 11:15:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70518 Wed 07 Feb 2024 08:13:03 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70519 Wed 07 Feb 2024 08:12:51 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65773 Tue 30 Jan 2024 21:24:39 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65777 Tue 30 Jan 2024 21:24:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65807 Tue 30 Jan 2024 21:24:10 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65808 Tue 30 Jan 2024 21:24:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72818 Tue 28 May 2024 16:09:35 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72817 Tue 28 May 2024 16:01:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72816 Tue 28 May 2024 15:46:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72815 Tue 28 May 2024 15:27:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72814 Tue 28 May 2024 15:20:36 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72812 Tue 28 May 2024 15:20:25 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72813 Tue 28 May 2024 15:12:51 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72810 Tue 28 May 2024 14:38:37 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72809 Tue 28 May 2024 14:31:15 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72808 Tue 28 May 2024 13:08:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72807 Tue 28 May 2024 12:53:34 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72806 Tue 28 May 2024 12:42:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72805 Tue 28 May 2024 12:33:16 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72798 Tue 28 May 2024 12:10:59 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72796 Tue 28 May 2024 11:57:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72792 Tue 28 May 2024 11:02:00 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72791 Tue 28 May 2024 10:46:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65843 Tue 14 May 2024 21:17:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71627 Tue 14 May 2024 19:46:24 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71629 Tue 14 May 2024 19:32:24 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65775 100 kDa through ultracentrifugation. Mass spectrometry also detected the most abundant peak for all fucoidans to be around 700 Da (m/z). Extracted fucoidans inhibited the activity of α-glucosidase more strongly than the commercial anti-diabetic agent acarbose but were inactive on α-amylase. Fucoidans were also shown to be mixed inhibitors of α-glucosidase. Compellingly, fucoidans synergistically inhibited α-glucosidase in combination with the anti-diabetic agent acarbose, highlighting prospects for combination therapy. Finally, fucoidans demonstrated some anti-proliferative characteristics on HCT116 cancer cells by inhibiting their ability to adhere to the tissue culture plate matrix. Furthermore, some fucoidan extracts inhibited the migration of HCT116 cancer cells from 3D spheroids. Some of our fucoidan extracts also inhibited HCT116 colony formation, demonstrating inhibition of long-term cell survival. The E. maxima water extract also inhibited glucose uptake by HCT116 cells, thereby influencing the glycolytic flux. In conclusion, biologically active fucoidans were successfully extracted from South African brown seaweeds. These fucoidans demonstrated anti-diabetic and anti-cancer properties, revealing their relevance as potential drugs for these diseases.]]> Thu 11 Jan 2024 18:08:05 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65763 200 km). These characteristics provide opportunities for high levels of connectivity, and as such, the stock structure is not well understood. We applied an integrated, multidisciplinary approach to provide an improved understanding of the complex stock structure dynamics for Patagonian toothfish on the Patagonian Shelf, specifically in relation to the shelf, slope, and deep-sea plains around the Falkland Islands. Research results were focused on aspects pertaining to (1) geographic variation in phenotypic characters (otolith shape); (2) a description of the spatial-temporal distribution patterns; (3) the active movements of deep-sea adults (tag-recapture study); and (4) the identification of early life-history dispersal through otolith microstructure and microchemical chronologies. Results from the study indicate high regional connectivity during the early life-history stages derived from at least two spawning contingents into spatially discrete nursery areas (cohort groups) on the Falklands Shelf. Fish followed distinct ontogenetic pathways into deeper waters adjacent to the areas wherein juvenile settlement into a demersal habitat occurred. There is little to no evidence of mixing among cohort groups during their ontogenetic migration into deep-sea adult habitats, reflecting a mixed population based on oceanographically defined egg and larval dispersal. The majority of the adult component of the population continue to display high site fidelity. However, between 9 and 25% of the population, consisting predominantly of larger reproductively capable adults undertake long-distance dispersal behaviour, identified as home-range relocations from the adult deep-sea habitats towards three of the known southern spawning grounds in the region. Results are suggestive of a requirement for improved collaborative efforts for regionally-based management approaches with careful consideration of local stock contingents. Future monitoring and research priorities should focus on the identification of reproductive potential, dispersal pathways and settlement patterns of stock contingents to inform the dynamics of mixed stock origins across the Patagonian region. While many aspects regarding the stock structure remain unresolved, results derived from the current studies can be used to inform the development of management measures to ensure the continued recovery and sustainable management of Patagonian toothfish within the region.]]> Thu 11 Jan 2024 18:07:47 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70175 Thu 04 Jan 2024 11:00:40 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:69909 Thu 04 Jan 2024 10:53:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71625 Sun 25 Feb 2024 13:35:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65792 Sun 21 Jan 2024 14:23:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72886 Sun 02 Jun 2024 18:00:13 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72882 Sun 02 Jun 2024 13:54:34 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72881 Sun 02 Jun 2024 13:40:35 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72879 Sun 02 Jun 2024 12:43:01 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72877 Sun 02 Jun 2024 10:21:02 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72876 Sun 02 Jun 2024 10:09:50 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72875 Sun 02 Jun 2024 09:57:19 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72874 Sun 02 Jun 2024 09:31:48 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72873 Sun 02 Jun 2024 09:29:13 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72872 Sun 02 Jun 2024 09:14:49 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72871 Sun 02 Jun 2024 09:00:35 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72870 Sun 02 Jun 2024 08:46:34 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72869 Sun 02 Jun 2024 08:29:35 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72868 Sun 02 Jun 2024 08:17:39 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71628 Sat 17 Feb 2024 12:46:41 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:56772 Sat 17 Feb 2024 12:25:24 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71965 Sat 06 Apr 2024 15:13:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71964 Sat 06 Apr 2024 15:13:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71963 Sat 06 Apr 2024 14:59:11 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71962 0.5 mg/ml). The QDs also retained most of their fluorescence and properties and could easily be tracked in cells and visualized around the nucleus, indicating the successful internalization of the QDs in the cytosol. These results shows that encapsulation of CdTe multi-core-shell QDs in liposomes produce better bio-compatibility compared to multi-core-shell QDs and better than CNP coating. These particles therefore show good promise in cell-labelling, drug delivery studies. Their core-shell nanoparticles have also shown good behavior in enhancing the memory of a device which is based on some recent collaborated works.]]> Sat 06 Apr 2024 14:52:11 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71961 Sat 06 Apr 2024 14:42:26 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71960 Sat 06 Apr 2024 14:24:58 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71958 Sat 06 Apr 2024 13:48:43 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71957 Sat 06 Apr 2024 13:33:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71956 4 and Dst_ -50 nT was used as a criterion for geomagnetic disturbed conditions, while the four geomagnetically quiet days were selected each month based on Kp < 3. Observations of TIDs are made using Global Navigational Satellite Systems (GNSS) total electron content derived data. During quiet conditions, seven and two transhemispheric TIDs were identified over the African-European and American sectors, respectively. The observed TIDs originated from the wintertime hemisphere and propagated into the summertime hemisphere. The horizontal velocity, periods, and horizontal wavelengths of TIDs are in range of cH = 120-274 m/s, 48-80 min and _H = 379-1104 km, respectively. These quiet-time equatorward TIDs have been associated with tertiary gravity waves (GWs) from the dissipation of secondary GWs which are in turn generated from the dissipation of mountain waves (MWs) as a result of excited orographic forcing. The poleward TIDs during geomagnetically quiet conditions over the African and American sectors occur mainly during local daytime. Poleward TIDs were observed mostly in the African-European sector than the American sector. Their horizontal propagation velocities and periods range between 129-280 m/s and 39-70 min over African-European and American sectors. Although the mechanisms responsible for launching quiet-time poleward TIDs have not been established in this study, lower atmospheric processes such as convection systems, sudden stratospheric warming and cold weather fronts may have a role in their generation. During geomagnetic storms in the African sector, almost all poleward TIDs (with the exception of two cases) during the main phase were large-scale with horizontal velocities and periods ranging from 250-503 m/s and 30 min to 2 hours. During recovery phase, poleward TIDs fall under the category of medium scale. In the American sector, the majority of poleward TIDs occurred during the storm's main phase, as opposed to the African-European sector, which experienced a significant number of poleward TIDs during the recovery phase. The periods and horizontal velocities of TIDs range from 45 min-1.5 h and 180-296 m/s during main phase. During the recovery phase, the horizontal velocity and period range from 177-271 m/s and 40-1.5 h, respectively. Overall, it has been shown that statistically, changes in equatorial electrodynamics related to enhanced eastward electric _eld and hence increased equatorial electrojet (vertical E_B drift) correlates highly with the reported poleward TIDs.]]> Sat 06 Apr 2024 13:06:52 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71955 Sat 06 Apr 2024 12:42:05 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71954 Sat 06 Apr 2024 12:24:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72867 Sat 01 Jun 2024 20:44:21 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72866 Sat 01 Jun 2024 20:37:20 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72865 Sat 01 Jun 2024 20:28:07 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72864 Sat 01 Jun 2024 20:14:38 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72863 Sat 01 Jun 2024 20:03:32 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72862 Sat 01 Jun 2024 19:46:29 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72861 Sat 01 Jun 2024 19:34:23 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72859 Sat 01 Jun 2024 18:19:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72858 Sat 01 Jun 2024 18:07:33 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72857 Sat 01 Jun 2024 16:51:55 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72856 Sat 01 Jun 2024 16:38:40 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72855 3 Log10 CFU.mL−1 values. The dyes also exhibit moderate activities toward the S. aureus and E. coli biofilm cells, which are lower than for the planktonic cells, as shown by their lower Log10 reduction values. The data demonstrate that the low symmetry corrole, chlorin, and N-confused porphyrin complexes that absorb light strongly within the therapeutic window have significantly enhanced PDT and PACT activities relative to their porphyrin analogs.]]> Sat 01 Jun 2024 16:20:32 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72854 Sat 01 Jun 2024 16:16:17 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72853 Sat 01 Jun 2024 15:48:41 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72852 Sat 01 Jun 2024 12:46:58 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72851 Sat 01 Jun 2024 12:33:20 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72850 Sat 01 Jun 2024 12:24:46 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72849 Sat 01 Jun 2024 12:19:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72848 Sat 01 Jun 2024 12:09:38 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72847 Sat 01 Jun 2024 11:55:55 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70176 Mon 29 Jan 2024 11:36:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72790 Mon 27 May 2024 19:26:03 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72789 Mon 27 May 2024 19:04:37 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72788 Mon 27 May 2024 18:44:26 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72787 Mon 27 May 2024 18:35:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72786 Mon 27 May 2024 18:18:14 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72785 Mon 27 May 2024 18:09:02 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72784 Mon 27 May 2024 17:42:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72783 Mon 27 May 2024 17:19:38 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72782 Mon 27 May 2024 17:12:55 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:72781 Mon 27 May 2024 17:05:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70629 Mon 19 Feb 2024 21:09:31 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70174 Mon 18 Dec 2023 18:08:30 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:71626 Mon 13 May 2024 20:49:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70631 Mon 13 May 2024 20:28:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70630 Mon 13 May 2024 19:46:33 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:61170 Mon 08 Jan 2024 12:35:27 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70177 Mon 05 Feb 2024 08:27:19 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:65804 S0 excitation energies. The small deviation observed between the calculated and experimental spectra arises from the solvent effect. The excitation energies observed in these UV-Vis spectra mostly originated from electron promotion between the highest occupied molecular orbital (HOMO) for the less intense band and the HOMO-1 for the most intense band of the ground states to the lower unoccupied molecular orbital (LUMO) of the excited states.]]> Fri 17 May 2024 16:29:44 SAST ]]>