https://commons.ufh.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11829 Wed 12 May 2021 23:17:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:3859 Wed 12 May 2021 19:39:20 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11297 Wed 12 May 2021 15:55:31 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:52755 Tue 05 Jul 2022 15:13:11 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:10339 Thu 13 May 2021 07:36:07 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11278 10 mg/ml for the aqueous extract. The minimum bactericidal concentration (MBC) ranges of the extracts were 0.625–10 mg/ml for both the n-hexane and the dichloromethane extract; 5-10 mg/ml for the methanol extract; and those for the aqueous extract were above 10 mg/ml against all the susceptible Listeria isolates. The rate of kill analysis was then determined for the three most active crude extracts that is excluding the aqueous extract and it was assessed against four representative Listeria species namely L. monocytogenes (LAL 8), L. grayi (LAL 15), L. ivanovii (LEL 30) and L. ivanovii (LEL 18). All the three extracts showed a general trend of being concentration and time dependent in their rate of kill profiles such that most bacteria cells were killed at the highest test concentration of 4× MIC value after the maximum exposure time of 2 h. The n-hexane, dichloromethane and methanol extracts were bactericidal against 4, 3 and 1 isolates out of the four test Listeria isolates respectively.]]> Thu 13 May 2021 06:09:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:10316 125 μg/ml. These results suggest that the extract may be selective for specific cell types. Bio-assay guided fractionation of the S. ellipticum ethanolic extract yielded two active fractions; chloroform and ethyl acetate. Two compounds isolated from the chloroform extract were screened against the three cancer cell lines and found to be inactive. Three compounds were isolated from the ethyl acetate fraction and revealed IC50 values < 62.5 and < 31 μg/ml against MCF-7. Unfortunately these two compounds soon lost activity before any further work could be done on them and work was continued with the crude extract.]]> Thu 13 May 2021 05:53:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20498 Thu 13 May 2021 03:37:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11259 Thu 13 May 2021 03:10:48 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11253 Thu 13 May 2021 00:25:49 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:10315 Thu 13 May 2021 00:16:57 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:11336 Thu 13 May 2021 00:09:45 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:70513 Thu 08 Feb 2024 08:26:59 SAST ]]>