https://commons.ufh.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28506 Wed 31 May 2023 15:41:19 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41933 Wed 28 Sep 2022 14:29:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5148 Wed 26 Oct 2022 10:09:09 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:26750 Wed 20 Jul 2022 08:42:27 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27975 Wed 17 May 2023 13:00:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28308 Wed 15 Sep 2021 12:38:53 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41611 Wed 13 Mar 2024 14:10:26 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28757 Wed 13 Mar 2024 14:10:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:39508 Wed 13 Mar 2024 14:03:23 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35643 Wed 13 Mar 2024 11:50:28 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35510 Wed 13 Mar 2024 11:43:34 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:31348 Wed 13 Mar 2024 11:29:23 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:29807 Wed 13 Mar 2024 10:05:29 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4639 Wed 12 Oct 2022 12:31:41 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5127 30kg.m-2), as well as according to measures of waist circumference (WC) and body composition. Hypertension, hypercholesterolemia and type II diabetes, were grouped as cardiovascular (CV) risks. Hypertension was defined as a blood pressure greater than 140/90mmHg (JNC-7); hypercholesterolemia, as total cholesterol greater than 6.2mmol.L-1 (NCEP); and type II diabetes, as total glucose greater than 12mmol.L-1 (WHO). Physical activity, diet, tobacco use, and alcohol consumption and dependence were grouped as lifestyle-related risks. These were assessed by means of self-reporting through the use of various validated questionnaires. Finally, self-reporting of obesity, hypertension, hypercholesterolemia and type II diabetes was assessed, in addition to perception questions on individuals’ perceived body shape and size (Ziebland figures). Self-reported and perceived responses were then compared to actual measures. Females were significantly (p<0.001) heavier than the males (92.7kg compared to 72.1kg) and had significantly (p<0.001) higher BMIs than their male counterparts (37.6kg.m-2 compared to 25.7 kg.-2). They also recorded significantly (p<0.001) higher waist circumference (WC) values and had significantly (p<0.001) higher percentage and total body fat. Significantly (p<0.001) more females were obese (81%) compared to males (17%). While a higher percentage of males (25 % compared to 22%) presented with stage I hypertension (≥140/90mmHg, <160/95mmHg), significantly (p<0.05) more females (14% compared to 8%) presented with stage II hypertension (>160/95mmHg). The prevalence of hypercholesterolemia at a high level of risk (>6.2mmol.L-1) was relatively low (2.1 % of males, 3.4% of females), but notably more participants (22% of males and 26% of females) presented with the condition at a moderate level of risk (>5mmol.L-1). Type II diabetes was the least prevalent CV risk factor, with no males and only 3% of females presenting with the condition. Males consumed significantly (p<0.05) more in terms of total energy intake (9024 vs. 7234 kJ) and were significantly (p<0.05) more active (3315 compared to 2660 MET-mins.week). A significantly (p<0.05) higher percentage of males smoked (51.1% compared to 3.4%), consumed alcohol (73.4% compared to 46.6%) and were alcohol dependent (40% compared to 33.5%). Both males and females tended to be ignorant of their health status, with both samples under-reporting obesity, hypertension and hypercholesterolemia, while over-reporting type II diabetes. Furthermore, obesity was significantly (p<0.05) underestimated, with both male and female individuals perceiving themselves to be notably smaller than they actually were. Physical activity and diet were important determinants of CVD risk in this black urban sample of individuals. Obesity, in particular central adiposity, was the most notable risk (particularly in females), followed by hypertension (particularly in males). Although some risks presented at a moderate level of risk, a clustering of risk factors was evident in both samples, with 12.6% and 41.2% of males and females presenting with two risk factors, and 2.8% and 8.1% of males and females respectively presenting with three risks.]]> Wed 12 Oct 2022 12:08:41 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5100 Wed 12 Oct 2022 11:53:52 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5565 Wed 12 Oct 2022 08:26:31 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20351 Wed 12 Jul 2023 19:04:25 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4850 Wed 10 Aug 2022 06:00:16 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:30794 Wed 08 Feb 2023 09:51:50 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:30778 Wed 08 Feb 2023 09:41:49 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:3242 Wed 05 Apr 2023 08:08:59 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:26641 Wed 03 May 2023 13:21:12 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28488 Wed 03 May 2023 13:07:26 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28390 Tue 27 Jul 2021 16:09:02 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:3851 Tue 24 May 2022 16:01:37 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5809 Tue 24 Aug 2021 16:43:49 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4759 Tue 22 Nov 2022 10:03:40 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:21257 Tue 19 Jul 2022 11:57:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28387 Tue 16 May 2023 14:59:05 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28199 Tue 16 May 2023 12:53:17 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:21330 Tue 15 Aug 2023 11:29:32 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:30710 Tue 15 Aug 2023 11:20:55 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4147 Tue 15 Aug 2023 11:05:20 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5607 Tue 15 Aug 2023 10:51:57 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28605 Tue 13 Jun 2023 12:32:30 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27470 Tue 13 Jun 2023 09:02:08 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27814 Tue 12 Oct 2021 15:49:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:36614 5m). This study aimed to address this information gap. Dive surveys were conducted along 10 m long transects (~3 reps) at three depth zones (<1m; 1-2m; > 2m) for four sites along the span of the ranching concession area. Similar assessments were done at a seeded site at the Noordhoek Ski Boat Club and an unseeded site at the Willows area, in order to reveal whether seeding had any impact on the benthic community. Images from a GoPro mounted in the centre of a framer unit (0.5 m2) were taken every 0.5 m along the transect. Macroalgal and macrofaunal cover was determined from these images, and the benthic community characterised from these data. Seaweed samples were taken for species identification. In the four baseline sites, sampling was done at three depth zones to note any changes with a depth gradient, both in terms of substrate type, as well as community composition. There was a notable trend with substrate type having a significant influence (P<0.05) on the community structure. Seaweed communities were dominated by Plocamium corallorhiza and coralline turf based on substrate types. There was also a significant relationship (P<0.05) between substrate type, dominant seaweed species and abalone presence. A Canonical Correspondence Analysis (CCA) of the community data suggested that the benthic community does not change significantly along the distance of coastline sampled. A hierarchical cluster analysis of Bray-Curtis dissimilarity for transect data also suggested that the four sites do not represent ecologically dissimilar communities. A similar analysis showed that abalone seeding had to date not altered the benthic community in shallow seeded areas from the community described for shallow unseeded areas. The study was used to describe the baseline benthic community in areas west of Cape Recife, examine the natural variability along the coast, and determine whether there are relationships between the benthic community composition and emergent abalone abundance. This information will be useful in selection of habitats for abalone seeding in the future. It is important that monitoring and surveying of the study area are to be continued in so allowing for long term data collection which will help in making informed decisions as well as documenting the impact in seeded areas when compared to unseeded areas.]]> Tue 12 Mar 2024 15:12:54 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27356 Tue 09 May 2023 15:48:03 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27809 Tue 09 May 2023 10:46:58 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20381 Thu 29 Sep 2022 14:28:44 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:26094 Thu 29 Sep 2022 14:21:25 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:25988 Thu 29 Sep 2022 14:20:40 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5324 Thu 29 Sep 2022 14:19:13 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27799 Thu 29 Sep 2022 14:18:31 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5362 Thu 29 Sep 2022 14:15:59 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:29924 0.05), development or the active metabolic (P > 0.05) or metabolic scope (P > 0.05) of fish in the three treatments throughout the study. However, the standard metabolic rate was significantly higher in the year 2068 treatment but only at the flexion/post-flexion stage which could be attributed to differences in developmental rates (including the development of the gills) between the 2068 and the other two treatments. Overall, the metabolic scope was narrowest in the 2090 treatment, but varied according to life stage. Although not significantly different, metabolic scope in the 2090 treatment was noticeably lower at the flexion stage compared to the other two treatments, and the development appeared slower, suggesting that this could be the stage most prone to OA. The study concluded that, in isolation, OA levels predicted to occur between 2050 and 2090 will not negatively affect size-at-hatch, growth, development, and metabolic responses of larval A. japonicus up to 22 DAH (flexion/post-flexion stage). Taken together with the previous studies of the same species, the tipping point of tolerance (where negative impacts will begin) in larvae of the species appears to be between the years 2090 and 2100.]]> Thu 29 Sep 2022 12:56:05 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5483 Thu 26 Aug 2021 14:37:41 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28489 Thu 25 May 2023 13:00:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20338 Thu 23 Jun 2022 11:24:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28386 Thu 22 Jul 2021 15:55:21 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27615 Thu 18 May 2023 09:02:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20319 Thu 16 Mar 2023 12:59:53 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:42199 Thu 13 Jul 2023 12:40:08 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27805 Thu 13 Jul 2023 12:34:14 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4624 Thu 07 Jul 2022 20:23:25 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5857 Thu 05 Aug 2021 14:16:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28413 Thu 04 May 2023 11:21:57 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27791 Thu 01 Sep 2022 09:29:45 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28216 Thu 01 Jun 2023 09:58:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:29390 Sat 04 Dec 2021 12:43:33 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5745 Mon 30 Aug 2021 14:30:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28702 Mon 29 Jan 2024 14:44:58 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28417 Mon 22 May 2023 15:47:55 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:37114 Mon 22 Aug 2022 15:05:56 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:37128 Mon 22 Aug 2022 14:58:53 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:20722 Mon 12 Jun 2023 15:48:52 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5656 Mon 12 Jun 2023 15:39:03 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:21262 Mon 12 Jun 2023 12:17:56 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27629 Mon 03 Jul 2023 14:13:59 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4815 Fri 27 Aug 2021 09:43:48 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4885 Fri 23 Jun 2023 05:59:46 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:26997 Fri 23 Jul 2021 11:15:06 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4459 Fri 21 Jan 2022 11:52:32 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27408 Fri 19 May 2023 10:05:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27617 Fri 19 May 2023 09:37:03 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28388 Fri 17 Sep 2021 12:45:46 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27038 Fri 17 Sep 2021 10:11:50 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:5097 Fri 15 Oct 2021 15:17:21 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:39587 Fri 15 Mar 2024 13:12:42 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27316 Fri 15 Mar 2024 13:00:29 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:32614 Fri 15 Mar 2024 13:00:04 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27018 Fri 15 Mar 2024 12:32:30 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:30543 Fri 15 Mar 2024 12:32:16 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40457 Fri 15 Mar 2024 12:25:35 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:27011 Fri 15 Mar 2024 12:25:14 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41607 Fri 15 Mar 2024 12:11:18 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:37087 1, antagonism, respectively. Most combination treatments showed to have an antagonistic effect except for cisplatin:BC-7 (1:3, 1:1, 2:1, 3:1) and cisplatin:A. afra (1:3, 1:2, 1:1, 3:1) combinations that showed synergism. The 1:2 ratio of cisplatin:BC-7 and the 2:1 ratio of cisplatin:A. afra were additive. CI values were also calculated at inhibition of 10, 25 and 75% of HeLa cell growth, for each combination mixture. Antagonistic effects were frequently observed at lower effect levels such as at 10 and 25% inhibition of growth. However, this was not seen for the cisplatin:BC-7 combinations as all the ratios indicated synergism. Some of these ratios, such as the 1:3 and 1:2, even led to a greater degree of synergism being obtained, with noticeable antagonistic effects seen at 50 and 75% inhibition of growth. The current finding is that BC-7 and A. afra could lower the dose of cisplatin in combination to achieve a similar anti-cancer efficacy compared to the higher cisplatin dose when used alone. The lower dosage in combination could result in reduced drug resistance as well as limit the toxicity on normal cells associated with cisplatin treatment. In conclusion, this study shows, for the first time, that A. nemorosa has the potential to induce apoptosis and also has some anti- and pro-inflammatory activity in HeLa cancer cells. This study also enhanced the knowledge of the mechanism of apoptosis induction of BC-7, in a more detailed manner, as well as investigated its inflammatory effects for the first time. Results obtained for A. afra correlated nicely to previously reported studies and confirmed that the methods used in this study, although different, leads to the same conclusions. Combination treatments also indicated, for the first time, that BC-7 and A. afra have the ability to function in a synergic manner with cisplatin and proves that, although extensive research may have been done on a plant or compound, more can be discovered. This new information can lead to identification of new compounds in the plants and the integration of signalling pathways that can be targeted for treatment of cancer.]]> Fri 15 Mar 2024 11:56:53 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:37837 Fri 15 Mar 2024 09:30:02 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4131 Fri 10 Dec 2021 08:54:22 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:26596 Fri 09 Jun 2023 15:34:31 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28204 Fri 06 Aug 2021 11:56:45 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:3978 Fri 06 Aug 2021 11:41:17 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28490 Fri 06 Aug 2021 11:00:38 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28158 Fri 06 Aug 2021 10:26:50 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:4528 Fri 06 Aug 2021 10:23:42 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:3726 Fri 06 Aug 2021 10:17:09 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28034 Fri 02 Jun 2023 11:43:09 SAST ]]> https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28070 Fri 02 Jun 2023 09:09:15 SAST ]]>