https://commons.ufh.ac.za/vital/access/manager/Index en-us 5 Synthesis, characterization and biological activity of some Dithiourea Derivatives: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41007 Wed 07 Aug 2024 16:02:19 SAST ]]> A New Synthetic Method for Tetraazatricyclic Derivatives and Evaluation of Their Biological Properties https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35413 Wed 07 Aug 2024 16:02:18 SAST ]]> Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity. https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35362 125 μM) was observed. Similarly, these compounds exhibited moderate activity against the human protozoal pathogen Trichomonas vaginalis with no observed effect on common microbiome bacterial species. The cross-species inhibitory activity presents the possibility of these compounds serving as broad-spectrum antibiotics for these prevalent three human pathogens.]]> Tue 07 May 2024 12:34:59 SAST ]]> Indolyl-3-ethanone-α-thioethers: a promising new class of non-toxic antimalarial agents https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28920 Tue 07 May 2024 12:34:20 SAST ]]> Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28913 Tue 07 May 2024 12:33:27 SAST ]]> Synthesis, in vitro cytotoxicity and trypanocidal evaluation of novel 1, 3, 6-substituted non-fluoroquinolones https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35409 Tue 07 May 2024 12:33:05 SAST ]]> Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35407 50 % was often observed. Except for compound 9o, none of the final compounds exhibited cytotoxic effects against HeLa cells at 20 μM.]]> Tue 07 May 2024 12:31:51 SAST ]]> New thiazolidine-2,4-dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35382 90% viability of the HeLa cell line screened.]]> Tue 07 May 2024 12:31:21 SAST ]]> Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35410 Tue 07 May 2024 12:28:22 SAST ]]> Synthesis, structure and in vitro anti-trypanosomal activity of non-toxic Arylpyrrole-Based Chalcone derivatives: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:40096 Tue 07 May 2024 12:26:20 SAST ]]> Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers. https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35370 Tue 07 May 2024 12:11:09 SAST ]]> Ferrocenyl and organic novobiocin derivatives: synthesis and their in vitro biological activity https://commons.ufh.ac.za/vital/access/manager/Repository/vital:28914 Tue 07 May 2024 11:50:10 SAST ]]> Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41114 Tue 07 May 2024 11:47:49 SAST ]]> Novobiocin–ferrocene conjugates possessing anticancer and antiplasmodial activity independent of HSP90 inhibition. https://commons.ufh.ac.za/vital/access/manager/Repository/vital:35359 Tue 07 May 2024 11:27:40 SAST ]]> The in vitro antiplasmodial and antiproliferative activity of new ferrocene-based α-aminocresols targeting hemozoin inhibition and DNA interaction: https://commons.ufh.ac.za/vital/access/manager/Repository/vital:38827 Tue 07 May 2024 11:21:22 SAST ]]> Repurposing a polymer precursor: Synthesis and in vitro medicinal potential of ferrocenyl 1, 3-benzoxazine derivatives https://commons.ufh.ac.za/vital/access/manager/Repository/vital:41240 Tue 07 May 2024 11:20:07 SAST ]]>